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We cut through operational barriers so research studies can deliver answers faster.
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</li>
|
||
<li>
|
||
<a href="/research/our-impact/our-impact-clinical-trials" data-drupal-link-system-path="node/27434">Clinical Trials</a>
|
||
</li>
|
||
<li>
|
||
<a href="/research/our-impact/our-impact-drug-discovery-and-development" data-drupal-link-system-path="node/27394">Drug Discovery and Development</a>
|
||
</li>
|
||
<li>
|
||
<a href="/research/our-impact/our-impact-rare-diseases" data-drupal-link-system-path="node/27393">Rare Diseases</a>
|
||
</li>
|
||
<li class="active active-trail">
|
||
<a href="/research/our-impact/our-impact-research-operations" class="active active-trail active-trail is-active" data-drupal-link-system-path="node/27413">Research Operations</a>
|
||
</li>
|
||
<li class="last">
|
||
<a href="/research/our-impact/our-impact-tools-and-technologies" class="last" data-drupal-link-system-path="node/27396">Tools and Technologies</a>
|
||
</li>
|
||
</ul>
|
||
|
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|
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</nav>
|
||
|
||
|
||
</div>
|
||
|
||
<section>
|
||
<div class="container news-content Advancing">
|
||
<h2 class="section-heading">Starting Studies Sooner</h2>
|
||
|
||
|
||
<div class="paragraph paragraph--type--body-content paragraph--view-mode--default">
|
||
|
||
|
||
<div class="sidebar-right"><div class="image-box"><img src="/sites/default/files/styles/large/public/2023-09/Resources%20for%20Trainees%20Section_720x480.png?itok=1nFctA1F" alt="Lab technician"><div class="caption-text"><p>A researcher works in the lab at NCATS. (<em>Daniel Soñé Photography</em>)</p></div></div></div><p>There are many steps that happen before new research projects can start. They can include negotiating agreements, building new infrastructure and bringing in the right expertise. Each step takes time and, as a result, slows start times and ultimately the results.</p><p>We have made these and other steps in the process faster and more efficient – shaving weeks and months off of project timelines. Our solutions include agreement templates that lay out the basic rules in advance, so collaborators can more quickly concur on the details. We also have developed research resources like chemical libraries and large clinical research networks that easily pivot to new research opportunities.</p><p>Because we use these approaches, we were ready – and stand ready – to respond quickly to public health emergencies. During COVID-19, these approaches kick-started therapeutic development efforts, real-world data sharing and major clinical trials. We share what we’ve developed and learned to help others speed their research efforts.</p><p><a href="/research/our-impact">Explore All Areas of Our Impact</a></p>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<hr class="section-divider">
|
||
</div>
|
||
</section>
|
||
<section>
|
||
<div class="container news-content Advancing">
|
||
<h2 class="section-heading">Impact Stories</h2>
|
||
|
||
|
||
<div class="row vertical-line two-col">
|
||
<div class="col-xl-6 col-wrap">
|
||
<div class="pe-lg-4 p-0 col">
|
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|
||
|
||
<h2>National Pharmaceutical Collection (NPC)</h2>
|
||
<img src="/sites/default/files/2023-09/NCATS_PharmDrugInfographic_Concept%20620x275.png" class="w-100 mt-2">
|
||
<div class="description pt-4">
|
||
|
||
<p>The NCATS Pharmaceutical Collection is a comprehensive, publicly accessible collection of approved molecular entities for high-throughput screening that provides a valuable resource for both validating new models of disease and better understanding the molecular basis of diseases and interventions.</p>
|
||
</div>
|
||
|
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<div class="text-center button-wrap">
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<button class="buttons btn-1 mt-4"><a href="/research/research-resources/preclinical-research-toolbox/npc">Read More</a></button>
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|
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<div class="ps-lg-4 p-0 col">
|
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|
||
|
||
<div class="paragraph paragraph--type--body-content paragraph--view-mode--default">
|
||
|
||
|
||
<h2>How NCATS Compound Management Speeds New Therapies</h2><p><iframe width="560" height="315" src="https://www.youtube.com/embed/vrwnMFOImjg" title="YouTube video player" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" allowfullscreen></iframe></p><p>Kelli Wilson, Ph.D., director of Compound Management at NCATS, explains how the NCATS Compound Management group supports researchers via compound storage, registration, shipping and reformatting.</p><p>(video length: 2:48)</p>
|
||
|
||
</div>
|
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<div class="text-center button-wrap">
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<button class="buttons btn-1 mt-4"><a href="https://youtu.be/vrwnMFOImjg">Watch the Video</a></button>
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</div>
|
||
</div>
|
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|
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<hr class="section-divider">
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</div>
|
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</section>
|
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<section>
|
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<div class="container news-content Advancing">
|
||
<h2 class="section-heading">Research Operations Activities</h2>
|
||
<div class="description">
|
||
|
||
<p>We develop programs and resources that overcome operational barriers slowing down research projects.</p>
|
||
</div>
|
||
|
||
|
||
<div class="row mb-4 three-pic-cards">
|
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<div class="col-xl-4 ps-xl-3 mb-4">
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<div class="card border-0 p-0 radius-10 h-100">
|
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<div class="row p-20 g-4 align-items-stretch">
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|
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<img src="/sites/default/files/2023-09/CTSA%20Related%20Research%20card_746x370_0.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">Clinical and Translational Science Awards (CTSA) Program</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p>The CTSA Program addresses the development and implementation of national standards and best practices for translation, from basic discovery to clinical and community-engaged research.</p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
||
<a href="http://drupal9-ncats.scgcorp.com/research/research-activities/clinical-and-translational-science-awards">Learn More</a>
|
||
</div>
|
||
</div>
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|
||
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|
||
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|
||
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|
||
<div class="col-xl-4 ps-xl-3 mb-4">
|
||
<div class="card border-0 p-0 radius-10 h-100">
|
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<div class="row p-20 g-4 align-items-stretch">
|
||
<div class="col-xl-12 col-lg-6">
|
||
<img src="/sites/default/files/2023-09/Forms%20and%20Model%20Agreements_746x370_0.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">Partner Forms and Model Agreements</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p>We provide a full range of services to support NCATS technology development and partnership activities, including negotiating standard forms and model agreements between NCATS and outside parties.</p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
||
<a href="/research/alliances/forms-and-model-agreements">Learn More</a>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
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<div class="col-xl-4 ps-xl-3 mb-4">
|
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<div class="card border-0 p-0 radius-10 h-100">
|
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<div class="row p-20 g-4 align-items-stretch">
|
||
<div class="col-xl-12 col-lg-6">
|
||
<img src="/sites/default/files/2023-09/PaVe-GT%20Related%20Research%20card_746x370.png" class="img-fluid">
|
||
</div>
|
||
<div class="col-xl-12 col-lg-6">
|
||
<div class="card-body px-0 pt-0">
|
||
<h3 class="">Platform Vector Gene Therapy (PaVe-GT)</h3>
|
||
<p class="py-xl-0 py-lg-4 py-md-4 py-sm-4 py-2">
|
||
|
||
<p>Our pilot project is testing the feasibility of increasing the efficiency of gene therapy clinical trials by using the same gene delivery system and manufacturing methods for multiple gene therapies.</p>
|
||
|
||
</p>
|
||
</div>
|
||
<div class="card-footer bg-white border-0 p-0">
|
||
<a href="/research/research-resources/pave-gt">Learn More</a>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
<div class="text-center button-wrap">
|
||
<button class="buttons btn-1 mt-4"><a href="/research/research-activities">See All Research Operations Activities</a></button>
|
||
</div>
|
||
|
||
|
||
<hr class="section-divider">
|
||
</div>
|
||
</section>
|
||
<section>
|
||
<div class="container news-content Advancing">
|
||
<h2 class="section-heading">Research Operations News</h2>
|
||
|
||
|
||
<div class="paragraph paragraph--type--view paragraph--view-mode--default">
|
||
|
||
|
||
<div class="views-element-container"><div class="row col js-view-dom-id-eea0fc2e9b44cd9021b14916bf257ea846220e794b2c5f9d5cfc244c7014ac6b">
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|
||
|
||
|
||
|
||
|
||
<div class="views-element-container"><div class="row col js-view-dom-id-ce8814ece5841376f0d6ac41f3e8396ebd70d8d7f6ace2f32603edf46486b6d7">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="mb-4 featured views-row"><div class="featured usa-card__container mb-4 p-4">
|
||
<div class="row">
|
||
<div class="col-md-4 col-lg-2">
|
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|
||
|
||
<img loading="lazy" src="/sites/default/files/styles/media_library/public/1.png?itok=lVvOERYi" width="220" height="220" alt="NCATS DNA Roadmap" />
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="col-md-8 col-lg-10">
|
||
<h3 class="title">NIH Gene Therapy Team Reveals Its Path to FDA Orphan Drug and Rare Pediatric Disease Designations</h3>
|
||
<p class="m-0"><i>March 29, 2023 - NCATS News</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>Our Impact on Rare Diseases</i></li>
|
||
<li><i>Our Impact on Research Operations</i></li>
|
||
<li><i>Platform Vector Gene Therapy (PaVe-GT)</i></li>
|
||
</ul>
|
||
|
||
|
||
<p>When NCATS received an Orphan Drug Designation (ODD) from the U.S. Food and Drug Administration (FDA), it marked a key accomplishment for researchers in the NIH's Platform Vector Gene Therapy (PaVe-GT) project.</p>
|
||
|
||
<a href="/news/releases/2023/NIH-Gene-Therapy-Team-Reveals-Its-Path-to-FDA-Orphan-Drug-and-Rare-Pediatric-Disease-Designations">Read Article</a>
|
||
</div>
|
||
</div>
|
||
</div></div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
|
||
<div class="usa-card__body">
|
||
<h3 class="title">NIH Gene Therapy Team Reveals Its Path to FDA Orphan Drug and Rare Pediatric Disease Designations</h3>
|
||
<p class="m-0"><i>March 29, 2023 - NCATS News</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>Our Impact on Rare Diseases</i></li>
|
||
<li><i>Our Impact on Research Operations</i></li>
|
||
<li><i>Platform Vector Gene Therapy (PaVe-GT)</i></li>
|
||
</ul>
|
||
|
||
|
||
<p>When NCATS received an Orphan Drug Designation (ODD) from the U.S.</p>
|
||
|
||
</div>
|
||
<div class="usa-card__footer">
|
||
<a href="/news/releases/2023/NIH-Gene-Therapy-Team-Reveals-Its-Path-to-FDA-Orphan-Drug-and-Rare-Pediatric-Disease-Designations">Read Article</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
|
||
<div class="usa-card__body">
|
||
<h3 class="title">Nationwide IRB Reliance Agreement Aimed at Speeding Research Reaches 1,000 Signatories</h3>
|
||
<p class="m-0"><i>August 3, 2022 - NCATS News</i>
|
||
</p>
|
||
<ul class="list-pipe">
|
||
<li><i>Clinical and Translational Science Awards (CTSA) Program</i></li>
|
||
<li><i>Our Impact on Research Operations</i></li>
|
||
</ul>
|
||
|
||
|
||
<p>The Streamlined, Multisite, Accelerated Resources for Trials (SMART) Institutional Review Board (IRB) agreement has reached 1,000 participating sites, making it one of the largest medical research </p>
|
||
|
||
</div>
|
||
<div class="usa-card__footer">
|
||
<a href="/news-events/news/nationwide-IRB-reliance-agreement-aimed-at-speeding-research-reaches-1000-signatories">Read Article</a>
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</div>
|
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|
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<div class="col-sm-4 mb-4 views-row"><div class="usa-card__container">
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<div class="usa-card__body">
|
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<h3 class="title">EPA Holds Meeting on TSCA New Chemicals Collaborative Research Program</h3>
|
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<p class="m-0"><i>April 22, 2022 - Media Coverage</i>
|
||
</p>
|
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<ul class="list-pipe">
|
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<li><i>Our Impact on Research Operations</i></li>
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</ul>
|
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|
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</div>
|
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<div class="usa-card__footer">
|
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<a href="https://www.natlawreview.com/article/epa-holds-meeting-tsca-new-chemicals-collaborative-research-program">Read Article</a>
|
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</div>
|
||
</div>
|
||
</div>
|
||
|
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|
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|
||
|
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|
||
|
||
|
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|
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<button class="buttons btn-1 mt-4"><a href="/news-events/news?program%5B0%5D=Our%20Impact%20on%20Research%20Operations">See More Research Operations News</a></button>
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</article>
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<style type="text/css">
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ul#superfish-navigation li { line-height:1.25; }
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ul.sf-menu.sf-navigation li.menuparent ul {width:280px !important;}
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justify-content: space-between;
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white-space: unset;
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height: auto;
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}
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.caption-left-md {
|
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float: left;
|
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width: 50%;
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margin: 0 1% 2% 0;
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border: 1px solid #ddd;
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}
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width: 100%!important;
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height: auto;
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}
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div.block.block-layout-builder.block-field-blocknodestafffield-divisions-office {
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display: none
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p.last-update-container {
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font-size: 15px;
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font-style: italic;
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}
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<div class="container"><p class="last-update-container">Last updated on April 22, 2024</p></div>
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