nih-gov/ncats.nih.gov/news/news-events/deep-learning-model-predicts-best-time-monitor-atrial-fibrillation
2025-02-26 13:17:41 -05:00

441 lines
31 KiB
Text
Raw Permalink Blame History

This file contains ambiguous Unicode characters

This file contains Unicode characters that might be confused with other characters. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

<!DOCTYPE html>
<html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#">
<head>
<meta charset="utf-8" />
<meta name="description" content="A predictive computer model for atrial fibrillation could help clinicians decide when to start long-term monitoring to detect AF missed by a single test." />
<meta name="keywords" content="Atrial fibrillation, machine learning, cardiology" />
<link rel="canonical" href="http://ncats.nih.gov/news-events/news/deep-learning-model-predicts-best-time-monitor-atrial-fibrillation" />
<meta name="google" content="PROqkJCbtNawPO29xzL4ENjcb0_EckySw96i97QXx8s" />
<meta name="google-site-verification" content="PROqkJCbtNawPO29xzL4ENjcb0_EckySw96i97QXx8s" />
<meta property="og:description" content="A computer model could predict when to start long-term monitoring to detect atrial fibrillation missed by a single test." />
<meta name="Generator" content="Drupal 10 (https://www.drupal.org)" />
<meta name="MobileOptimized" content="width" />
<meta name="HandheldFriendly" content="true" />
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
<link rel="icon" href="/themes/custom/d9_subtheme/assets/images/favicon.ico" type="image/vnd.microsoft.icon" />
<title>Deep Learning Model Predicts Best Time to Monitor for Atrial Fibrillation | National Center for Advancing Translational Sciences</title>
<link rel="stylesheet" media="all" href="/libraries/drupal-superfish/css/superfish.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/ajax-progress.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/align.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/autocomplete-loading.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/fieldgroup.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/container-inline.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/clearfix.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/details.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/hidden.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/item-list.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/js.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/nowrap.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/position-container.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/progress.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/reset-appearance.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/resize.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/sticky-header.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-counter.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-report-counters.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-report-general-info.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/tabledrag.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/tablesort.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/system/css/components/tree-child.module.css?srmo5o" />
<link rel="stylesheet" media="all" href="/modules/contrib/extlink/extlink.css?srmo5o" />
<link rel="stylesheet" media="all" href="/core/modules/layout_discovery/layouts/onecol/onecol.css?srmo5o" />
<link rel="stylesheet" media="all" href="https://cdn.jsdelivr.net/npm/@uswds/uswds@3.3.0/dist/css/uswds.min.css" />
<link rel="stylesheet" media="all" href="https://cdn.jsdelivr.net/npm/bootstrap@5.0.2/dist/css/bootstrap.min.css" />
<link rel="stylesheet" media="all" href="https://cdn.jsdelivr.net/npm/bootstrap-icons@1.11.1/font/bootstrap-icons.css" />
<link rel="stylesheet" media="all" href="/themes/custom/d9_subtheme/css/styles.css?srmo5o" />
<script src="https://dap.digitalgov.gov/Universal-Federated-Analytics-Min.js?agency=HHS&amp;subagency=NIH" id="_fed_an_ua_tag" async type="text/javascript"></script>
</head>
<body class="path-node page-node-type-feature">
<a href="#main-content" class="usa-sr-only focusable">
Skip to main content
</a>
<noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-55CGV66V"
height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
<section class="navigation-top">
<div class="container">
<div class="row">
<div class="col-12">
<div class="link-small d-flex">
<a href="http://www.hhs.gov/" title="Go to the hhs.gov" class="" target="_blank">
<img src="/sites/default/files/2023-10/hhs-white.png" alt="HHS Logo">
<span class="d-xl-inline d-lg-inline d-none small">U.S. Department of Health &amp; Human Services</span>
</a>
<a href="http://www.nih.gov/" title="National Institutes of Health | Homepage" class="" target="_blank">
<img src="/sites/default/files/2023-10/nih-logo.png" alt="NIH Logo">
<span class="d-xl-inline d-lg-inline d-none small">National Institutes of Health</span>
</a>
</div>
</div>
</div>
</div>
</section>
<div class="usa-overlay"></div>
<header class="usa-header usa-header--extended usa-header--extended-megamenu" id="header" role="banner">
<div class="region region-header grid-container">
<div class="grid-row grid-gap-1"><div class="desktop:grid-col-3 header-first">
<div class="usa-logo site-logo" id="logo">
<em class="usa-logo__text">
<a class="logo-img" href="/" accesskey="1" title="Home" aria-label="Home">
<img src="/themes/custom/d9_subtheme/logo.png" alt="Home" />
</a>
</em>
</div>
<div class="search-icon d-md-none"><a class="toggle-search" href="#"><i class="bi bi-search"></i></a></div>
</div><div class="desktop:grid-col-7">
<div id="block-navigation" class="block block-superfish block-superfishnavigation">
<ul id="superfish-navigation" class="menu sf-menu sf-navigation sf-horizontal sf-style-none">
<li id="navigation-menu-link-contentaed842ec-f581-4cea-b0b0-4a85c50def86" class="sf-depth-1 menuparent"><a href="/research" class="sf-depth-1 menuparent">Research</a><ul><li id="navigation-menu-link-content5a3b6aac-7ae9-45d7-929f-fbf776db20f0" class="sf-depth-2 sf-no-children"><a href="/research/overview" class="sf-depth-2">Research Overview</a></li><li id="navigation-menu-link-contentd0507d8b-7b88-453c-908a-2b7e961c0479" class="sf-depth-2 sf-no-children"><a href="/research/our-impact" class="sf-depth-2">Our Impact</a></li><li id="navigation-menu-link-contented530d1e-2ec3-46db-a529-9029be3f3fb4" class="sf-depth-2 sf-no-children"><a href="/research/research-activities" class="sf-depth-2">Research Activities</a></li><li id="navigation-menu-link-content2dac8545-38f2-47c0-8993-ea0cae65e123" class="sf-depth-2 sf-no-children"><a href="/research/research-resources" class="sf-depth-2">Research Resources</a></li><li id="navigation-menu-link-content311ec98e-6232-4e22-9966-4a9ac796870a" class="sf-depth-2 sf-no-children"><a href="/research/training-education" class="sf-depth-2">Training &amp; Education</a></li><li id="navigation-menu-link-content52b1ba41-94ea-4d84-9db7-7482b8f78f16" class="sf-depth-2 sf-no-children"><a href="/research/alliances" class="sf-depth-2">Alliances</a></li><li id="navigation-menu-link-contenta185af75-90a5-4cc4-813f-ef66f35e21ea" class="sf-depth-2 sf-no-children"><a href="/research/collaborate-with-ncats" class="sf-depth-2">Collaborate With NCATS</a></li></ul></li><li id="navigation-menu-link-content84a3cc1f-203d-4de6-ab26-d80c256b96dc" class="sf-depth-1 menuparent"><a href="/funding" class="sf-depth-1 menuparent">Funding</a><ul><li id="navigation-menu-link-content0a09bed2-3d99-4faf-b3c5-fc9a4878629a" class="sf-depth-2 sf-no-children"><a href="/funding/overview" class="sf-depth-2">Funding Overview</a></li><li id="navigation-menu-link-contentd85a1f38-7893-4e4a-8514-5b9e767983e2" class="sf-depth-2 sf-no-children"><a href="/funding/funding-opportunities" class="sf-depth-2">Open Funding Opportunities</a></li><li id="navigation-menu-link-content81e84c00-ef73-4aff-a15f-7728cc398801" class="sf-depth-2 sf-no-children"><a href="/funding/small-business-programs" class="sf-depth-2">Small Business Programs</a></li><li id="navigation-menu-link-content631a166b-650b-450f-97b4-9014d14935e9" class="sf-depth-2 sf-no-children"><a href="/funding/funding-policy-operating-guidelines" class="sf-depth-2">Funding Policy &amp; Operating Guidelines</a></li><li id="navigation-menu-link-content5d56ebe7-b3e8-452a-bd30-df92b0deabef" class="sf-depth-2 sf-no-children"><a href="/funding/grant-information" class="sf-depth-2">Grant Information</a></li><li id="navigation-menu-link-content4429fdc9-e911-4022-b3dc-3f6a4980b9ff" class="sf-depth-2 sf-no-children"><a href="/funding/challenges" class="sf-depth-2">Challenges and Prize Competitions</a></li><li id="navigation-menu-link-content943fe682-94ff-4fcf-a6b0-32096d2b2d0e" class="sf-depth-2 sf-no-children"><a href="/funding/scientific-review" class="sf-depth-2">Scientific Review</a></li><li id="navigation-menu-link-content10496705-320e-4437-b2ba-ea2830b293d1" class="sf-depth-2 sf-no-children"><a href="/funding/conference-grant-information" class="sf-depth-2">Conference Grant Information</a></li></ul></li><li id="navigation-menu-link-contentea91f2ef-1b8d-4b1c-83e7-5830769dd505" class="sf-depth-1 menuparent"><a href="/resources" class="sf-depth-1 menuparent">Resources For You</a><ul><li id="navigation-menu-link-content567e64e3-685d-41bc-8bf4-130c7689d6a2" class="sf-depth-2 sf-no-children"><a href="/resources/overview" title="Resources for You" class="sf-depth-2">Resources for You</a></li><li id="navigation-menu-link-content786ce1f5-ff7a-463a-bb05-c01882062426" class="sf-depth-2 sf-no-children"><a href="/resources/for-researchers" title="Resources for Researchers" class="sf-depth-2">Resources for Researchers</a></li><li id="navigation-menu-link-contente737ec67-ecd0-4f18-915d-b61660cb524f" class="sf-depth-2 sf-no-children"><a href="/resources/for-trainees" title="Resources for Trainees" class="sf-depth-2">Resources for Trainees</a></li><li id="navigation-menu-link-content8812fdb6-0fb7-4b27-8401-2fc5b3f41ff1" class="sf-depth-2 sf-no-children"><a href="/resources/for-rare-disease-patients-and-advocates" title="Resources for Rare Disease Patients and Advocates" class="sf-depth-2">Resources for Rare Disease Patients and Advocates</a></li></ul></li><li id="navigation-menu-link-contenta8527040-df23-4117-a5a7-566bd83e2c7f" class="sf-depth-1 menuparent"><a href="/news-events" class="sf-depth-1 menuparent">News &amp; Events</a><ul><li id="navigation-menu-link-contentf6836a81-a42a-4528-b569-18939d8451da" class="sf-depth-2 sf-no-children"><a href="/news-events/overview" class="sf-depth-2">News &amp; Events Overview</a></li><li id="navigation-menu-link-content9f44edc6-e5b7-4a92-bcb3-c0a8777461f4" class="sf-depth-2 sf-no-children"><a href="/news-events/news" class="sf-depth-2">News</a></li><li id="navigation-menu-link-content402cff9f-12b7-459b-9f0f-56606930399c" class="sf-depth-2 sf-no-children"><a href="/news-events/newsletter" class="sf-depth-2">Newsletters</a></li><li id="navigation-menu-link-content6cd76cbe-053e-4e3b-8961-c9f5def57ba6" class="sf-depth-2 sf-no-children"><a href="/news-events/events" class="sf-depth-2">Events</a></li><li id="navigation-menu-link-content0a211675-2fb5-45cc-b443-c7946e7d9120" class="sf-depth-2 sf-no-children"><a href="/news-events/science-publications" class="sf-depth-2">Scientific Publications</a></li><li id="navigation-menu-link-contente6d4ed4f-826f-41b4-a9e2-728c2fb4ca62" class="sf-depth-2 sf-no-children"><a href="/news-events/multimedia" class="sf-depth-2">Multimedia</a></li></ul></li><li id="navigation-menu-link-contentf1eb1fa8-5813-433c-9bcc-dc56f2e258f3" class="sf-depth-1 menuparent"><a href="/about" class="sf-depth-1 menuparent">About NCATS</a><ul><li id="navigation-menu-link-contentada9a195-ae5a-446a-9014-c1232164e6db" class="sf-depth-2 sf-no-children"><a href="/about/ncats-overview" class="sf-depth-2">NCATS Overview</a></li><li id="navigation-menu-link-contentd5e0369a-aded-4348-84f7-463c64498447" class="sf-depth-2 sf-no-children"><a href="/about/about-translational-science" class="sf-depth-2">About Translational Science</a></li><li id="navigation-menu-link-contente298b7b2-724e-408b-9bb9-afcaac57a751" class="sf-depth-2 sf-no-children"><a href="/about/advisory-committees" class="sf-depth-2">Advisory Committees</a></li><li id="navigation-menu-link-contentbc9c91b7-8d3d-4d2c-af65-c25ef894d269" class="sf-depth-2 sf-no-children"><a href="/about/budget" class="sf-depth-2">Budget</a></li><li id="navigation-menu-link-contenta4ed4439-05db-4a41-9357-731c2ff74543" class="sf-depth-2 sf-no-children"><a href="/about/director" class="sf-depth-2">Director&#039;s Corner</a></li><li id="navigation-menu-link-contentb50f96af-3723-4634-8566-4e60c2639491" class="sf-depth-2 sf-no-children"><a href="/about/divisions-and-offices" class="sf-depth-2">Divisions &amp; Offices</a></li><li id="navigation-menu-link-content41d11ad4-c576-46be-a326-1f8cf5059354" class="sf-depth-2 sf-no-children"><a href="/about/our-staff" class="sf-depth-2">Our Staff</a></li></ul></li>
</ul>
</div>
</div>
<div class="desktop:grid-col-2 search-block">
<form class="usa-search usa-search--small" action="/search/node" method="get" id="search-block-form" accept-charset="UTF-8">
<div role="search">
<input class="usa-input" id="extended-search-field-small" type="search" name="keys" />
<button class="usa-button" type="submit">
<img src="/themes/custom/d9_subtheme/node_modules/@uswds/uswds/dist/img/usa-icons-bg/search--white.svg" class="usa-search__submit-icon" alt="Search">
</button>
</div>
</form>
</div></div>
</div>
<nav class="usa-nav" role="navigation">
<div class="usa-nav__inner">
<button type="button" class="usa-nav__close">
<img src="/themes/custom/d9_subtheme/node_modules/@uswds/uswds/dist/img/usa-icons/close.svg" alt="close"/>
</button>
</div>
</nav>
</header>
<main class="main-content usa-layout-docs usa-section " role="main"
id="main-content">
<div class="grid-container-">
<div class="grid-row">
</div>
<div class="">
</div>
<div class="grid-row ">
</div>
<div class="grid-row grid-gap">
<div class="usa-layout-docs__main desktop:grid-col-fill">
<div class="">
<div data-drupal-messages-fallback class="hidden"></div>
<div id="block-d9-subtheme-content" class="block block-system block-system-main-block">
<article data-history-node-id="42680">
<div>
<div class="container layout layout--onecol">
<div class="layout__region layout__region--content">
<div class="block block-system block-system-breadcrumb-block">
<nav class="usa-breadcrumb" role="navigation" aria-labelledby="system-breadcrumb">
<h2 id="system-breadcrumb" class="usa-sr-only">Breadcrumb</h2>
<ol class="usa-breadcrumb__list">
<li class="usa-breadcrumb__list-item">
<a href="/" class="usa-breadcrumb__link"><span>Home</span></a>
</li>
<li class="usa-breadcrumb__list-item">
<a href="/news-events/overview" class="usa-breadcrumb__link"><span>News &amp; Events</span></a>
</li>
<li class="usa-breadcrumb__list-item">
<a href="/news-events/news" class="usa-breadcrumb__link"><span>News</span></a>
</li>
<li class="usa-breadcrumb__list-item">
<span>Deep Learning Model Predicts Best Time To Monitor For Atrial Fibrillation</span>
</li>
</ol>
</nav>
</div>
</div>
</div>
<div class="container layout layout--onecol">
<div class="layout__region layout__region--content">
<div class="block block-layout-builder block-field-blocknodefeaturefield-feature-header-image">
</div>
<div class="block block-layout-builder block-field-blocknodefeaturebody">
<script type="text/javascript" src="https://platform-api.sharethis.com/js/sharethis.js#property=6553a9484ba88b0012e52dfe&amp;product=inline-share-buttons&amp;source=platform" async="async"></script><style>
.img-responsive {
height: auto;
}
</style><h1>CTSA Researchers Use Deep Learning Model to Predict Best Time to Monitor for Atrial Fibrillation</h1><div class="sidebar-right image-box"><img class="img-responsive" src="/sites/default/files/2024-01/NCATS_atrial_fib_feature_900x600.jpg" alt="Doctor checks patients heart." width="900" height="600"><div class="caption-text"><p>A doctor holds a stethoscope to check the heart and lungs of an elderly male patient. <em>(Shutterstock)</em></p></div></div><p>January 25, 2024</p><p>A predictive computer model for atrial fibrillation (AF), the most common form of irregular heartbeat, could help doctors decide when to start long-term monitoring to detect AF that may have been missed by a single test. The approach was developed by scientists supported by the Clinical and Translational Science Awards (CTSA) Program and the National Institute on Aging.</p><p>AF can cause blood clots, stroke, heart failure and other heart-related conditions. About one in three people with AF have an occasional and sudden form called paroxysmal AF. Long-term monitoring can catch paroxysmal AF, but deciding who to test and when to test them is challenging.</p><p>To sharpen predictions, scientists at Scripps Research Translational Institute and their colleagues reviewed information from 446,900 people who wore simple, single-lead electrocardiogram (ECG) devices to detect AF. The research teams computer model studied the ECG readings from periods when patients were not experiencing AF to find factors that helped predict which people were likely to have AF soon after.</p><p>When testing the model against past data, the computer model alone was better at predicting AF within 2 weeks than models that relied only on such factors as a persons age, gender, heart rate variability, odd heartbeats and heart rhythms. Combining the computer model with all those factors delivered the most accurate prediction, although the computer model alone nearly matched that combination model.</p><p>Learn more about the study findings in <a href="https://pubmed.ncbi.nlm.nih.gov/38087028/" target="_blank"><em>NPJ Digital Medicine</em></a>.</p><hr><div class="sharethis-inline-share-buttons">&nbsp;</div>
</div>
<div class="block block-layout-builder block-extra-field-blocknodefeaturecontent-moderation-control">
</div>
</div>
</div>
</div>
</article>
</div>
<div id="block-footercss" class="block block-block-content block-block-content2db33373-6fb7-49c5-be2f-83266eddea39">
<style type="text/css">
ul#superfish-navigation li { line-height:1.25; }
.region-header .block-superfish ul.sf-menu li a {padding-right:40px !important;}
@media (min-width: 1200px) {
ul.sf-menu.sf-navigation li.menuparent ul {width:280px !important;}
}
.main-content article .menu--navigation {
display:flex;
flex-wrap: nowrap;
justify-content: space-between;
align-items: stretch;
}
.main-content article .menu--navigation li {
flex: 1 1 0;
width: 0;
align-items: center;
display: flex;
justify-content: center;
}
.main-content article .menu--navigation li .dropdown-toggle {
white-space: unset;
}
.image-box img,
div.col-md-4.col-lg-2 img {
height: auto;
}
.caption-left-md {
float: left;
width: 50%;
margin: 0 1% 2% 0;
border: 1px solid #ddd;
}
.caption-left-md img {
width: 100%!important;
height: auto;
}
div.block.block-layout-builder.block-field-blocknodestafffield-divisions-office {
display: none
}
@media (max-width: 992px) {
.main-content article .menu--navigation {
flex-direction:column;
}
.main-content article .menu--navigation li {
display:inline-block;
margin:0;
padding:.25rem;
width: auto;
text-align:left;
}
.main-content article .menu--navigation li:hover, .main-content article .menu--navigation li.active {
border-bottom: 4px solid transparent !important;
}
.main-content article .menu--navigation li:hover a, .main-content article .menu--navigation li.active a {
border-bottom:4px solid #00626f !important;
padding-bottom:4px;
}
}
p.last-update-container {
font-size: 15px;
font-style: italic;
}
</style>
</div>
</div>
</div>
</div>
</div>
</main>
<div>
<div id="block-d9-subtheme-lastupdateblock" class="block block-ncats-common block-last-update-block">
<div class="container"><p class="last-update-container">Last updated on February 21, 2024</p></div>
</div>
</div>
<footer class="pt-4 footer mt-4">
<div class="container">
<div class="row">
<div class="col-12 py-4">
<img src="/sites/default/files/2023-10/ncats-logo-footer.png" class="img-fluid" alt="NCATS">
</div>
</div>
<div class="row">
<div class="container">
<div class="row justify-content-between">
<div class="col-xl-4">
<div class="pt-4">
<address>
9609 Medical Center Drive<br>
Rockville, MD 20850-9793<br>
301-594-8966<br>
<a href="mailto:ncatsinfo@nih.gov">ncatsinfo@nih.gov</a>
</address>
</div>
<div class="text-white social-links mt-4">
<h5>Connect with us</h5>
<ul id="social-media-icons" class="list-unstyled d-flex mb-4">
<li><a href="http://www.facebook.com/ncats.nih.gov" title="Visit us on Facebook" target="_blank"><i class="bi bi-facebook"></i></a></li>
<li><a href="https://www.linkedin.com/company/nih-ncats" title="Visit us on LinkedIn" target="_blank"><i class="bi bi-linkedin"></i></a></li>
<li><a href="http://www.twitter.com/ncats_nih_gov" title="Visit us on X" target="_blank"><i class="bi bi-twitter-x"></i></a></li>
<li><a href="http://www.youtube.com/user/ncatsmedia" title="View our videos on YouTube" target="_blank"><i class="bi bi-youtube"></i></a></li>
<li><a href="https://www.flickr.com/photos/64860478@N05/" target="_blank" title="View our photos on Flickr"><img src="/sites/default/files/2023-10/flickr.png" alt="View our photos on Flickr" style="height:24px;"></a></li>
</ul>
<p class="small">For <a href="http://edi.nih.gov/consulting/language-access-program/about" target="_blank">language access assistance</a>, contact the <a href="mailto:ncatsinfo@nih.gov">NCATS Public Information Officer</a></p>
</div>
</div>
<div class="col-xl-3 text-white mt-5 d-lg-none d-sm-none d-none d-xl-block">
<div id="mc_embed_shell">
<div id="mc_embed_signup">
<form action="https://nih.us5.list-manage.com/subscribe/post?u=e06bd55ccbb41f1a362306dff&amp;id=d32fa404b4&amp;f_id=0087b1edf0" method="post" id="mc-embedded-subscribe-form" name="mc-embedded-subscribe-form" class="validate" target="_blank">
<h5>Subscribe to NCATS News</h5>
<p>If you would like to stay up to date with the latest information from us, please sign up for NCATS News.</p>
<div id="mce-responses" class="clear">
<div class="response" id="mce-error-response" style="display: none;"></div>
<div class="response" id="mce-success-response" style="display: none;"></div>
</div>
<div class="input-group mb-3">
<input type="email" name="EMAIL" class="required email form-control" id="mce-EMAIL" required="" value="" placeholder="Enter Email" aria-label="Recipient's username" aria-describedby="button-addon2" tabindex="-1">
<div aria-hidden="true" style="position: absolute; left: -5000px;"><input type="text" name="b_e06bd55ccbb41f1a362306dff_d32fa404b4" tabindex="-1" value=""></div>
<button type="submit" name="subscribe" id="mc-embedded-subscribe" class="button btn" value="Subscribe">Submit</button>
</div>
</form>
</div>
<script type="text/javascript" src="//s3.amazonaws.com/downloads.mailchimp.com/js/mc-validate.js"></script><script type="text/javascript">(function($) {window.fnames = new Array(); window.ftypes = new Array();fnames[0]='EMAIL';ftypes[0]='email';fnames[1]='FNAME';ftypes[1]='text';fnames[2]='LNAME';ftypes[2]='text';fnames[3]='SIGNUP';ftypes[3]='text';}(jQuery));var $mcj = jQuery.noConflict(true);</script></div>
</div>
</div>
</div>
</div>
</div>
<!-- footer menu section -->
<section class="footer-menu py-3 mb-xl-0 mb-lg-0 mb-sm-5 mt-4">
<div class="container">
<div class="row">
<div class="col-12">
<ul class="list-unstyled d-xl-flex d-lg-flex d-sm-block d-block justify-content-center mb-0">
<li><a href="https://ncats.nih.gov/">NCATS Home</a></li>
<li><a href="/sitemap">Site Map</a></li>
<li><a href="/privacy">Privacy Notice</a></li>
<li><a href="/comments">Comment Policy</a></li>
<li><a href="/accessibility">Accessibility</a></li>
<li><a href="/foia">FOIA</a></li>
<li><a href="http://oig.hhs.gov/" target="_blank">OIG</a></li>
<li class="border-0"><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" target="_blank">HHS Vulnerability Disclosure</a></li>
</ul>
</div>
</div>
</div>
</section>
</footer>
</div>
<script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/42680","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJx1j8EOwjAMQ3-o0DNfU2Vt1pWlzdSkbPt7OgkhQONi2c_yweHmpA06YUYLIqhiwgfCTbEWoAt02TV5MR1RKrMNtS1A11c0kTkSOoVoY5fffIU7bN8wG4Kdm7qQxPMD6265oGcy0hasY5LJvt0Zc9OxSkWx6GkvGYjEV8Ry3h-uf5V_7cKSNHFf76KY7QCCpskaxB3WjhUyrlznJ5W4glk","theme":"d9_subtheme","theme_token":null},"ajaxTrustedUrl":[],"gtm":{"tagId":null,"settings":{"data_layer":"dataLayer","include_classes":false,"allowlist_classes":"","blocklist_classes":"","include_environment":false,"environment_id":"","environment_token":""},"tagIds":["GTM-55CGV66V"]},"gtag":{"tagId":"G-ZZQ8H5G8ZX","otherIds":[],"events":[],"additionalConfigInfo":[]},"data":{"extlink":{"extTarget":true,"extTargetNoOverride":false,"extNofollow":false,"extNoreferrer":true,"extFollowNoOverride":false,"extClass":"ext","extLabel":"(link is external)","extImgClass":false,"extSubdomains":true,"extExclude":"","extInclude":"","extCssExclude":"","extCssExplicit":"","extAlert":true,"extAlertText":"You are leaving the NIH website.\r\n\r\nThis external link provides additional information that is consistent with the intended purpose of this site. NIH cannot attest to the accuracy of a non-federal site.\r\n\r\nLinking to a non-federal site does not constitute an endorsement by NIH or any of its employees of the sponsors or the information and products presented on the site. You will be subject to the destination site\u0027s privacy policy when you follow the link.","mailtoClass":"mailto","mailtoLabel":"(link sends email)","extUseFontAwesome":false,"extIconPlacement":"append","extFaLinkClasses":"fa fa-external-link","extFaMailtoClasses":"fa fa-envelope-o","whitelistedDomains":[]}},"superfish":{"superfish-navigation":{"id":"superfish-navigation","sf":{"animation":{"opacity":"show","height":"show"},"speed":"fast"},"plugins":{"smallscreen":{"mode":"window_width","accordionButton":0,"title":"Navigation"},"supposition":true,"supersubs":true}}},"user":{"uid":0,"permissionsHash":"24b2a698a72e7a44d4f2d94d9880a6ba82bfbc8b8200dee23422144335254cbc"}}</script>
<script src="/core/assets/vendor/jquery/jquery.min.js?v=3.7.1"></script>
<script src="/core/assets/vendor/once/once.min.js?v=1.0.1"></script>
<script src="/core/misc/drupalSettingsLoader.js?v=10.2.3"></script>
<script src="/core/misc/drupal.js?v=10.2.3"></script>
<script src="/core/misc/drupal.init.js?v=10.2.3"></script>
<script src="/core/assets/vendor/tabbable/index.umd.min.js?v=6.2.0"></script>
<script src="https://cdn.jsdelivr.net/npm/@uswds/uswds@3.3.0/dist/js/uswds.min.js"></script>
<script src="/core/misc/progress.js?v=10.2.3"></script>
<script src="/core/assets/vendor/loadjs/loadjs.min.js?v=4.2.0"></script>
<script src="/core/misc/debounce.js?v=10.2.3"></script>
<script src="/core/misc/announce.js?v=10.2.3"></script>
<script src="/core/misc/message.js?v=10.2.3"></script>
<script src="/core/misc/ajax.js?v=10.2.3"></script>
<script src="/themes/custom/d9_subtheme/js/script.js?v=10.2.3"></script>
<script src="/modules/contrib/extlink/extlink.js?v=10.2.3"></script>
<script src="/modules/contrib/google_tag/js/gtm.js?srmo5o"></script>
<script src="/modules/contrib/google_tag/js/gtag.js?srmo5o"></script>
<script src="/modules/contrib/google_tag/js/gtag.ajax.js?srmo5o"></script>
<script src="/libraries/drupal-superfish/superfish.js?srmo5o"></script>
<script src="/libraries/drupal-superfish/jquery.hoverIntent.minified.js?srmo5o"></script>
<script src="/libraries/drupal-superfish/sfsmallscreen.js?srmo5o"></script>
<script src="/libraries/drupal-superfish/supposition.js?srmo5o"></script>
<script src="/libraries/drupal-superfish/supersubs.js?srmo5o"></script>
<script src="/modules/contrib/superfish/js/superfish.js?v=2.0"></script>
</body>
</html>