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<h2 class="section-heading">Videos</h2>
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<p>Watch our collection of videos to learn more about NCATS and get a behind-the-scenes look at our research activities.</p>
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<h2 class="section-heading">NCATS Infographics & Fact Sheets</h2>
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<p>View our fact sheets to learn more about us and download them to share our resources and activities with others.</p>
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</style><section class="usa-section" style="padding-bottom:0;padding-top:0;"><div class="grid-container"><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="https://ncats.nih.gov/sites/default/files/2024-02/3-d%20tissue%20models%20factsheet.PNG" target="_blank"><img class="usa-image img-border shadow" src="https://ncats.nih.gov/sites/default/files/2024-02/3-d%20tissue%20models%20factsheet.PNG" alt="The first page of a fact sheet about 3-D tissue models with a banner image at the top followed by text." width="400" height="519"></a></div><div class="grid-col-10"><h3>3-D Tissue Models</h3><p>NCATS designs and helps develop 3-D tissue models to help researchers better predict which promising treatments will move from the lab to success in clinical trials in people.</p><p><a href="/sites/default/files/2024-02/NCATS-2023-3D-Tissue-Models-Fact-Sheet-508.pdf" target="_blank">Read About 3-D Tissue Models</a> (PDF - 222KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/agm-factsheet.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/Program-Initiative-factsheets-image2.png" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="319" height="401"></a></div><div class="grid-col-10"><h3>Assay Guidance Manual</h3><p>The Assay Guidance Manual is a free, best-practices online resource devoted to the successful development of robust, early-stage drug discovery assays.</p><p><a href="/sites/default/files/agm-factsheet.pdf" target="_blank">Read About AGM</a> (PDF - 228KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/translator/projects#biomedical-translator-graphic" title="Biomedical Data Translator"><img class="shadow infographic" src="/sites/default/files/NCATS_TranslatorInfographic_v2%20FINAL.jpg" alt="A researcher types into the computer screen “predict treatments for disease y.” The query is sent to the Translator’s Autonomous Relay Agents (ARAs) to determine how best to answer the query. The ARA will then break the query into smaller tasks that are transmitted to rich, specialty knowledge bases called Knowledge Providers (KPs). This process will be iterative, such that the ARAs and KPs can build on information from the others. The last sequence is the results of the query showing up on the computer screen of the researcher." width="3835" height="1533"></a></div><div class="grid-col-10"><h3>Biomedical Data Translator</h3><p>This program brings together teams of experts from leading universities and research institutions to combine vast amounts of current medical research data and speed the development of new treatments.</p><p><a href="/research/research-activities/translator/projects" title="Biomedical Data Translator">Learn More About Translator Projects</a></p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="https://ncats.nih.gov/sites/default/files/2024-03/NCATS_FY-2025_CJ-Fact-Sheet_508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/2024-04/CJFY2025-graphic.JPG" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="237" height="312"></a></div><div class="grid-col-10"><h3>Congressional Justification</h3><p>The budget for NCATS is based on the fiscal year appropriation provided by Congress and the U.S. President. The Congressional Justification provides Congress detailed estimates and justifications for research.</p><p><a href="/sites/default/files/2024-03/NCATS_FY-2025_CJ-Fact-Sheet_508.pdf" target="_blank">Read About the Congressional Justification</a> (PDF - 843KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/NCATS-Core-Fact-Sheet-508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/Program-Initiative-factsheets-image9.png" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="259" height="334"></a></div><div class="grid-col-10"><h3>Core Technologies</h3><p>NCATS uses state-of-the-art resources and core technologies to enable the ongoing operation of all translational research activities happening at the Center.</p><p><a href="/sites/default/files/NCATS-Core-Fact-Sheet-508.pdf" target="_blank">Read About Core Technologies</a> (PDF - 250KB)</p></div></div></div><!--
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<a href="/sites/default/files/2024-02/NCATS_IDeaS-Fact-Sheet_March-2023_RF508_FV.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/styles/large/public/2024-02/NCATS_IDeaS-Fact-Sheet_March-2023_RF508_FV_thumbnail.png?itok=g5QuZEGi" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="234" height="303"></a>
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Economic Burden of Rare Diseases
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A study led by NCATS estimates the direct medical costs of rare diseases and the lengthy journey some people with rare diseases travel to an accurate diagnosis.
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<a href="/sites/default/files/2024-02/NCATS_IDeaS-Fact-Sheet_March-2023_RF508_FV.pdf" target="_blank">Read About the Economic Burden of Rare Diseases</a> (PDF - 675KB)
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--><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2024-06/NCATS-N3C-One-Pager-508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/2024-06/Program-Initiative-factsheets-image11v2.png" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="416" height="539"></a></div><div class="grid-col-10"><h3>National COVID Cohort Collaborative</h3><p>The National COVID Cohort Collaborative (N3C) maintains one of the largest collections of secure and deidentified clinical data in the United States for COVID-19 research.</p><p><a href="/sites/default/files/2024-06/NCATS-N3C-One-Pager-508.pdf" target="_blank">Read About N3C</a> (PDF - 296KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2023-11/NCATS-2023_Drug-Repurposing-Fact-Sheet-508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/2023-11/NCATS%20Drug%20Repurposing%20fact%20sheet%20thumbnail.PNG" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="640" height="832"></a></div><div class="grid-col-10"><h3>NCATS Drug Repurposing</h3><p>Drug repurposing finds approved drugs and investigational compounds that might be able to treat other diseases and conditions. We use drug repurposing as a key strategy for bringing more treatments for all people more quickly.</p><p><a href="/sites/default/files/2023-11/NCATS-2023_Drug-Repurposing-Fact-Sheet-508.pdf">Read About NCATS Drug Repurposing</a> (PDF - 688KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/expertise/preclinical/npc#NCATS-Pharmaceutical-Collection-Infographic" title="NCATS National Pharmaceutical Collection"><img class="shadow infographic" src="/sites/default/files/NCATS_Pharmaceutical_Collection_thumbnail.png" alt="The NCATS Pharmaceutical Collection (NPC) is a storehouse of approved drugs. Scientists use the collection to identify potential ways to repurpose drugs for new uses. Over the past 10 years, researchers used the NPC to study an array of pathways and disease models, generating an unparalleled amount of data. A number of projects produced drugs with new potential uses that have entered clinical trials, or have shown activity in testing, for several diseases and viruses. The NPC contains nearly 3,000 small molecule drugs. More than 300 requests for collaborations to screen the NPC resulted in 200 plus collaborative projects in such areas as rare and neglected diseases, infectious diseases and cancer. Illustration of a human body surrounded by names of several diseases that point to a specific location in the body." width="797" height="393"></a></div><div class="grid-col-10"><h3>NCATS National Pharmaceutical Collection</h3><p>The NCATS National Pharmaceutical Collection is a complete, publicly available collection of approved molecular parts for high-throughput screening. The collection provides a valuable resource for validating new models of disease and understanding the molecular basis of diseases and interventions better.</p><p><a href="/expertise/preclinical/npc#NCATS-Pharmaceutical-Collection-Infographic" title="NCATS National Pharmaceutical Collection">Learn More About the Pharmaceutical Collection</a> (PDF - 451KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2024-07/NCATS-OpenData-Portal-Fact-Sheet-2024-508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/NCATS-OpenData-Portal-Fact-Sheet-2024-508.jpg" alt width="416" height="538"></a></div><div class="grid-col-10"><h3>NCATS OpenData Portal</h3><p>The OpenData Portal offers real-time information about how individual SARS-CoV-2 variants may respond to known therapeutics. It also focuses on NCATS’ broader drug repurposing findings and other pandemic threats.</p><p><a href="/sites/default/files/2024-07/NCATS-OpenData-Portal-Fact-Sheet-2024-508.pdf" target="_blank">Read About the OpenData Portal</a> (PDF - 241KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2024-09/NCATS-Strategic-Plan-Framework-508.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/inline-images/NCATS_Screenshot.png" alt="NCATS Strategic Framework" width="400" height="513"></a></div><div class="grid-col-10"><h3>NCATS Strategic Plan Framework</h3><p>The Strategic Plan Framework includes 5 goals with supporting objectives to bring more treatments for all people more quickly.</p><p><a href="/sites/default/files/2024-09/NCATS-Strategic-Plan-Framework-508.pdf" target="_blank">View the NCATS Strategic Plan Framework</a> (PDF - 1.22 MB)</p></div></div></div><!--
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Rare Diseases
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NCATS supports a range of innovative approaches for understanding and treating rare diseases, which affect about 30 million people in this country.
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<a href="/sites/default/files/NCATS_RareDiseasesFactSheet.pdf" target="_blank">Read About Rare Diseases</a> (PDF - 330KB)
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--><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2024-11/NCATS-Rare-Diseases-Infographic-November-2024-508.pdf"><img class="usa-image img-border shadow" src="/sites/default/files/2024-11/NCATS-Rare-Diseases-Infographic-November-2024-508_800x640.png" alt="Rare Diseases: Individually Rare, Collectively Common. NCATS is developing new approaches to diagnose and treat people with rare diseases more quickly. NCATS logo. Resources. Providing high-quality, widely used resources like the Genetic and Rare Diseases Information Center (GARD), to educate, engage and empower the rare diseases community. Getting an accurate rare disease diagnosis can take more than 6 years, on average, leading to higher healthcare costs. GARD staff have answered about 120,000 questions. Capabilities. Developing platform technologies like high-throughput drug screening and gene-targeted therapies, that address many rare diseases at a time. Funding. Funding nationwide and international programs, like the Rare Diseases Clinical Research Network (RDCRN), to accelerate medical research across rare diseases. There are more than 10,000 rare diseases and only 5% of them have treatments. The RDCRN has helped move 12 rare disease treatments to the clinic." width="NaN" height="NaN"></a></div><div class="grid-col-10"><h3>Rare Diseases Overview</h3><p>NCATS is developing new approaches to diagnose and treat people with rare diseases more quickly.</p><p><a href="/sites/default/files/2024-11/NCATS-Rare-Diseases-Infographic-November-2024-508.pdf">View the Rare Diseases Infographic</a> (PDF - 110.14 KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/training-education/skills#seven-characteristics-of-a-translational-scientist" title="Seven Characteristics of a Translational Scientist"><img class="shadow infographic" src="/sites/default/files/Seven_Characteristics_Translational_Scientist_thumbnail.png" alt="Seven characteristics of a translational scientist include: boundary crosser, team player, process innovator, domain expert, rigorous researcher, skilled communicator and systems thinker" width="903" height="663"></a></div><div class="grid-col-10"><h3>Seven Characteristics of a Translational Scientist</h3><p>Translational scientists are innovative and collaborative, searching for ways to break down barriers in the translation process.</p><p><a href="/training-education/skills#seven-characteristics-of-a-translational-scientist" title="Seven Characteristics of a Translational Scientist">Learn More About the Characteristics of a Translational Scientist</a></p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/NCATS_SBIR-STTR_FactSheet_December-2022.pdf" target="_blank"><img class="usa-image img-border shadow" src="/sites/default/files/Program-Initiative-factsheets-image14.png" alt="The first page of a fact sheet about rare diseases with a banner image at the top followed by text." width="350" height="453"></a></div><div class="grid-col-10"><h3>Small Business Innovation</h3><p>The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs engage U.S. small businesses and research organizations in research and development that has the potential for commercialization and public benefit.</p><p><a href="/sites/default/files/NCATS_SBIR-STTR_FactSheet_December-2022.pdf" target="_blank">Read About SBIR/STTR Programs</a> (PDF - 250KB)</p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/tissuechip/chip#chip" title="Tissue Chip for Drug Screening"><img class="shadow infographic" src="/sites/default/files/16-540-NCATS_Chip-Organs_900x900.png" alt="Picture of person called “chip” with 13 clickable icons representing tissues and organ systems they represent, 2 icons are not clickable. The clickable icons are: brain; lungs, heart, muscle, liver, kidneys, gastrointestinal system, female reproductive system, blood vessels, fat, joints, skin and disease models. The two unclickable icons represent the ear and male reproductive system." width="900" height="900"></a></div><div class="grid-col-10"><h3>Tissue Chips for Drug Screening</h3><p>Developing new treatments for patients is a long and hard process. Often tests conducted in the early stages of research do not accurately predict how well a treatment will work or if it will cause any harm to humans. This leads to long delays and enormous costs while patients eagerly await effective treatments. The Tissue Chip for Drug Screening program at NCATS brings innovation to the table. By using specialized chips, this program is making exciting advancements in drug testing.</p><p><a href="/tissuechip/chip#chip" title="Tissue Chip for Drug Screening">Learn More About Tissue Chips</a></p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2025-01/TSP_badge_7_400x400.png" title="Translational Science Principles"><img class="shadow infographic" src="/sites/default/files/2025-01/TSP_badge_7_400x400.png" alt="Infographic displaying the badges that represent the seven Translational Science Principles." width="3841" height="3841"></a></div><div class="grid-col-10"><h3>Translational Science Principles</h3><p>Our seven translational science principles describe core approaches for effective translational science.</p><p><a href="/sites/default/files/2025-01/TSP_badge_7_400x400.png" title="Translational Science Principles">View the Translational Science Principles</a></p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/2023-10/NCATS_Translational_Science_Infographic.jpg" title="Translational Science"><img class="shadow infographic" src="/sites/default/files/2023-10/NCATS_Translational_Science_Infographic.jpg" alt="Infographic displaying the badges that represent the eight Translational Science Principles." width="1600" height="3166"></a></div><div class="grid-col-10"><h3>Translational Science</h3><p>Translational science looks at the entire translational research ecosystem to identify common pitfalls and develop innovative solutions.</p><p><a href="/sites/default/files/2023-10/NCATS_Translational_Science_Infographic.jpg" title="Translational Science Infographic">View the Translational Science Infographic</a></p></div></div></div><div class="card"><div class="grid-row table-row"><div class="col-lg"><a href="/sites/default/files/styles/large/public/2023-11/TranslationalScienceSpectrumGraphicStatic_FV_600x634_trans_no-cred.png" title="Translational Science Spectrum"><img class="shadow infographic" src="/sites/default/files/styles/large/public/2023-11/TranslationalScienceSpectrumGraphicStatic_FV_600x634_trans_no-cred.png" alt="Infographic displaying the Translational Science Spectrum." width="480" height="479"></a></div><div class="grid-col-10"><h3>Translational Science Spectrum</h3><p>The translational science spectrum covers all stages of research from basic research to public health.</p><p><a href="/sites/default/files/styles/large/public/2023-11/TranslationalScienceSpectrumGraphicStatic_FV_600x634_trans_no-cred.png" title="Translational Science Spectrum">View the Translational Science Spectrum</a></p></div></div></div></div></section>
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