nih-gov/medlineplus.gov/ency/article/003876.htm
2025-02-26 13:17:41 -05:00

294 lines
No EOL
32 KiB
HTML
Raw Permalink Blame History

This file contains ambiguous Unicode characters

This file contains Unicode characters that might be confused with other characters. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

<!DOCTYPE html>
<html lang="en" id="article" class="nojs us" data-root="//medlineplus.gov" itemid="https://medlineplus.gov/ency/article/003876.htm" itemtype="http://schema.org/MedicalWebPage" itemscope="">
<head>
<meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"/>
<meta http-equiv="window-target" content="_top"/>
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8"/>
<meta charset="utf-8"/>
<meta property="fb:app_id" content="1042245625821448"/>
<meta name="expires" content="Wed, 05 02 2025"/>
<meta name="ac-dictionary" content="medlineplus-ac-dictionary"/>
<link rel="shortcut icon" href="https://medlineplus.gov/images/favicon.ico" type="image/x-icon"/>
<link rel="apple-touch-icon" href="//medlineplus.gov/images/touch-icon.png"/>
<meta name="viewport" content="width=device-width, initial-scale=1"/>
<link rel="stylesheet" href="https://medlineplus.gov/css/common_new.css?04272023"/>
<!--[if IE 8]> <link rel="stylesheet" href="https://medlineplus.gov/css/ie8/common.css"><![endif]-->
<link rel="stylesheet" href="https://medlineplus.gov/uswds/css/uswds_styles.css"/>
<link rel="stylesheet" href="https://medlineplus.gov/css/ency/ency2.css?07162024"/>
<script type="text/javascript">document.querySelector("html").className = document.querySelector("html").className.replace(/nojs[\s]*/g, '');</script>
<script src="https://medlineplus.gov/uswds/js/uswds-init.min.js" type="text/javascript">
</script>
<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&amp;l='+l:'';j.async=true;j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-MMVM77');</script>
<link rel="canonical" href="https://medlineplus.gov/ency/article/003876.htm" itemprop="url"/>
<link rel="alternative" hreflang="es" href="https://medlineplus.gov/spanish/ency/article/003876.htm"/>
<link rel="alternative" hreflang="en" href="https://medlineplus.gov/ency/article/003876.htm"/><meta property="og:title" content="Coronary angiography: MedlinePlus Medical Encyclopedia"/><meta property="og:url" content="https://medlineplus.gov/ency/article/003876.htm"/><meta property="twitter:title" content="Coronary angiography: MedlinePlus Medical Encyclopedia"/><meta name="twitter:card" content="summary_large_image"/><meta name="description" content="Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. "/><meta itemprop="description" name="description" content="Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. "/><meta property="og:description" content="Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. "/><meta property="twitter:description" content="Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. "/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_1.jpg"/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_2.jpg"/><meta property="og:image" content="https://medlineplus.gov/images/share_ency_3.jpg"/><meta property="twitter:image" content="https://medlineplus.gov/images/share_ency_1.jpg"/>
<title>Coronary angiography: MedlinePlus Medical Encyclopedia</title>
</head>
<body><link href="http://schema.org/Patient" itemprop="audience"/>
<!-- Google Tag Manager -->
<noscript><iframe title="googletagmanager" src="//www.googletagmanager.com/ns.html?id=GTM-MMVM77" height="0" width="0" style="display:none;visibility:hidden">
</iframe>
</noscript>
<!-- End Google Tag Manager -->
<a name="top" id="top">
</a>
<a class="hide-offscreen" href="#start">Skip navigation</a>
<section class="usa-banner" aria-label="Official website of the United States government">
<div class="usa-accordion">
<header class="usa-banner__header">
<div class="usa-banner__inner">
<div class="grid-col-auto">
<img aria-hidden="true" class="usa-banner__header-flag" src="https://medlineplus.gov/uswds/img/us_flag_small.png" alt=""/>
</div>
<div class="grid-col-fill tablet:grid-col-auto" aria-hidden="true">
<p class="usa-banner__header-text">
An official website of the United States government
</p>
<p class="usa-banner__header-action">Heres how you know</p>
</div>
<button type="button" class="usa-accordion__button usa-banner__button" aria-expanded="false" aria-controls="gov-banner-default-default">
<span class="usa-banner__button-text">Heres how you know</span>
</button>
</div>
</header>
<div class="usa-banner__content usa-accordion__content" id="gov-banner-default-default">
<div class="grid-row grid-gap-lg">
<div class="usa-banner__guidance tablet:grid-col-6">
<img class="usa-banner__icon usa-media-block__img" src="https://medlineplus.gov/uswds/img/icon-dot-gov.svg" role="img" alt="" aria-hidden="true"/>
<div class="usa-media-block__body">
<p>
<strong>Official websites use .gov</strong><br/>A
<strong>.gov</strong> website belongs to an official government
organization in the United States.
</p>
</div>
</div>
<div class="usa-banner__guidance tablet:grid-col-6">
<img class="usa-banner__icon usa-media-block__img" src="https://medlineplus.gov/uswds/img/icon-https.svg" role="img" alt="" aria-hidden="true"/>
<div class="usa-media-block__body">
<p>
<strong>Secure .gov websites use HTTPS</strong><br/>A
<strong>lock</strong> (
<span class="icon-lock"><svg xmlns="http://www.w3.org/2000/svg" width="52" height="64" viewBox="0 0 52 64" class="usa-banner__lock-image" role="img" aria-labelledby="banner-lock-description-default" focusable="false">
<title id="banner-lock-title-default">Lock</title>
<desc id="banner-lock-description-default">Locked padlock icon</desc>
<path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z">
</path>
</svg> </span>) or <strong>https://</strong> means youve safely connected to
the .gov website. Share sensitive information only on official,
secure websites.
</p>
</div>
</div>
</div>
</div>
</div>
</section>
<div id="mplus-wrap">
<header>
<div id="mplus-header">
<!-- Orgs
================================================== -->
<div id="mplus-orgs">
<a title="National Institutes of Health" target="_blank" class="nih-org" href="//www.nih.gov/">
<img alt="National Institutes of Health" src="https://medlineplus.gov/images/nihlogo.png" class="nihlogo"/>
</a><a target="_blank" href="https://www.nlm.nih.gov/"> National Library of Medicine </a>
</div>
<!-- Logo
================================================== -->
<div id="mplus-logo" class="years-25">
<a href="https://medlineplus.gov">
<img src="https://medlineplus.gov/images/m_logo_25.png" title="MedlinePlus Trusted Health Information for You" alt="MedlinePlus Trusted Health Information for You"/>
</a>
</div>
<!-- Nav Menu
================================================== -->
<div id="mplus-nav">
<div class="sm-live-area hide-offscreen" aria-live="polite">The navigation menu has been collapsed.</div>
<!-- Menu Button-->
<button type="submit" aria-controls="mplus-menu-list" role="button" title="Menu" class="navmenu-btn" id="sm-menu-btn" aria-pressed="false" tabindex="0">Menu<span class="icon icon-nav-menu">
</span></button><ul class="nav-list" id="mplus-menu-list">
<li><a href="https://medlineplus.gov/healthtopics.html">Health Topics</a></li>
<li><a href="https://medlineplus.gov/druginformation.html">Drugs &amp; Supplements</a></li>
<li><a href="https://medlineplus.gov/genetics/">Genetics</a></li>
<li><a href="https://medlineplus.gov/lab-tests/">Medical Tests</a></li>
<li><a href="https://medlineplus.gov/encyclopedia.html">Medical Encyclopedia</a></li>
<li><a href="https://medlineplus.gov/about/">About MedlinePlus</a></li>
</ul><button type="submit" aria-controls="mplus-search" role="button" title="Search" class="navmenu-btn" id="sm-search-btn" aria-pressed="false" tabindex="0"><span class="hide-offscreen">Show </span>Search<span class="icon icon-nav-search">
</span></button>
<div class="top-1">
<!-- Search
================================================== -->
<form target="_self" title="Search MedlinePlus" action="//vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta" method="get" id="mplus-search">
<input type="hidden" value="medlineplus" name="v:project"/>
<input type="hidden" value="medlineplus-bundle" name="v:sources"/>
<div class="form-box text-combo">
<div class="form-area"><label for="searchtext_primary" class="hide-offscreen">Search MedlinePlus</label>
<span role="status" aria-live="polite" class="ui-helper-hidden-accessible">
</span><input type="text" aria-haspopup="true" aria-autocomplete="list" role="textbox" autocomplete="off" name="query" size="40" maxlength="400" title="Site Search input" alt="Site Search input" placeholder="Search MedlinePlus" class="form-text ui-autocomplete-input" id="searchtext_primary"/>
</div>
<div class="button-area">
<button type="submit" alt="Search MedlinePlus" title="Search MedlinePlus" class="form-btn">GO</button>
</div>
</div>
</form>
<!-- Secondary Nav
================================================== -->
<div class="secondarynav">
<ul class="nav-list">
<li><a href="https://medlineplus.gov/about/"><span>About MedlinePlus</span></a></li>
<li><a href="https://medlineplus.gov/whatsnew/"><span>What's New</span></a></li>
<li><a href="https://medlineplus.gov/sitemap.html"><span>Site Map</span></a></li>
<li><a target="_blank" href="https://support.nlm.nih.gov/knowledgebase/category/?id=CAT-01231&amp;category=medlineplus&amp;from=//medlineplus.gov/ency/article/003876.htm"><span>Customer Support</span></a></li>
</ul>
</div>
</div>
<!-- Nav Bar
================================================== -->
<div id="mplus-nav-bar">
<ul class="nav-list">
<li><a href="https://medlineplus.gov/healthtopics.html">Health Topics</a></li><li><a href="https://medlineplus.gov/druginformation.html">Drugs &amp; Supplements</a></li><li><a href="https://medlineplus.gov/genetics/">Genetics</a></li><li><a href="https://medlineplus.gov/lab-tests/">Medical Tests</a></li><li><a href="https://medlineplus.gov/encyclopedia.html">Medical Encyclopedia</a></li>
</ul>
</div>
<a title="Español" id="mplus-lang-toggle" href="../../spanish/ency/article/003876.htm">Español</a>
</div>
</div>
</header>
<!-- Content
================================================== -->
<div id="mplus-content">
<!-- Breadrcumbs -->
<div id="breadcrumbs"><div itemtype="http://schema.org/BreadcrumbList" itemscope="" itemprop="breadcrumb"><span class="hide-offscreen">You Are Here:</span>
<div itemscope itemprop="itemListElement" itemtype="http://schema.org/ListItem">
<a href="https://medlineplus.gov" itemprop="item"><span itemprop="name">Home</span></a>
&rarr;
<meta itemprop="position" content="1"/>
</div>
<div itemscope itemprop="itemListElement" itemtype="http://schema.org/ListItem">
<a href="https://medlineplus.gov/encyclopedia.html" itemprop="item"><span itemprop="name">Medical Encyclopedia</span></a>
&rarr;
<meta itemprop="position" content="2"/>
</div>
</div><div><span>Coronary angiography</span></div></div>
<span class="page-url print-only">URL of this page: //medlineplus.gov/ency/article/003876.htm
</span>
<!-- Article -->
<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
</a><h1 class="with-also" itemprop="name">Coronary angiography</h1>
</div><div class="page-actions">
</div>
<noscript>
<span class="js-disabled-message">To use the sharing features on this page, please enable JavaScript.</span>
</noscript></div><div class="main"><div id="ency_summary"><p>Coronary angiography is a procedure that uses a special dye (contrast material) and x-rays to see how blood flows through the arteries in your heart. </p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-1"><p>Coronary angiography is sometimes performed with <a test="test" href="./003419.htm">cardiac catheterization</a>. This is a procedure that measures pressures in the heart chambers.</p><p>Before the test starts, you will be given a mild sedative to help you relax.</p><p>An area of your body (the arm or groin) is cleaned and numbed with a local numbing medicine (anesthetic). The cardiologist passes a thin hollow tube, called a catheter, through an artery and carefully moves it up into the heart. X-ray images help the doctor position the catheter.</p><p>Once the catheter is in place, dye (contrast material) is injected into the catheter. X-ray images are taken to see how the dye moves through the artery. The dye helps highlight any blockages in blood flow.</p><p>The procedure most often lasts 30 to 60 minutes.</p><img title="Coronary angiography" alt="Coronary angiography" src="//medlineplus.gov/ency/images/ency/fullsize/18129.jpg" class="img-e" itemprop="image"/></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How to Prepare for the Test</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-2"><p>You should not eat or drink anything for 8 hours before the test starts.</p><p>You will wear a hospital gown. You must sign a consent form before the test. Your health care provider will explain the procedure and its risks.</p><p>Tell your provider if you: </p><ul><li>Are allergic to any medicines or if you have had a bad reaction to contrast material in the past</li><li>Are taking sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis) or other medicines from this class</li><li>Might be pregnant </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>How the Test will Feel</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-3"><p>In most cases, you will be awake during the test. You may feel some pressure at the site where the catheter is placed.</p><p>You may feel a flushing or warm sensation after the dye is injected.</p><p>After the test, the catheter is removed. You might feel a firm pressure being applied at the insertion site to prevent bleeding. If the catheter is placed in your groin, you will be asked to lie flat on your back for a few hours to several hours after the test to avoid bleeding. This may cause some mild back discomfort.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Why the Test is Performed</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-4"><p>Coronary angiography may be done if: </p><ul><li>You have angina for the first time.</li><li>Your angina that is becoming worse, not going away, occurring more often, or happening at rest (called <a test="test" href="./000201.htm">unstable angina</a>).</li><li>You have <a test="test" href="./000178.htm">aortic stenosis</a> or another heart valve problem.</li><li>You have atypical chest pain, when other tests are normal.</li><li>You had an abnormal heart stress test.</li><li>You are going to have surgery on your heart and you are at high risk for coronary artery disease.</li><li>You have <a test="test" href="./000158.htm">heart failure</a>.</li><li>You have been diagnosed as having a heart attack. </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Normal Results</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-5"><p>There is a normal supply of blood to the heart and no blockages.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What Abnormal Results Mean</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-6"><p>An abnormal result may mean you have a blocked artery. The test can show how many coronary arteries are blocked, where they are blocked, and the severity of the blockages.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Risks</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-7"><p>Cardiac catheterization carries a slightly increased risk when compared with other heart tests. However, the test is very safe when performed by an experienced team.</p><p>Generally, the risk for serious complications ranges from 1 in 1,000 to 1 in 500. Risks of the procedure include the following:</p><ul><li><a test="test" href="./000194.htm">Cardiac tamponade</a></li><li>Irregular heartbeats</li><li>Injury to a heart artery</li><li>Low blood pressure</li><li>Allergic reaction to contrast dye or a medicine administered during the exam</li><li><a test="test" href="./000726.htm">Stroke</a></li><li><a test="test" href="./000195.htm">Heart attack</a></li></ul><p>Considerations associated with any type of catheterization include the following:</p><ul><li>In general, there is a risk for bleeding, infection, and pain at the IV or catheter site.</li><li>There is a very small risk that the soft plastic catheters could damage the blood vessels or surrounding structures.</li><li>Blood clots could form on the catheters and later block blood vessels elsewhere in the body.</li><li>The contrast dye could damage the kidneys (particularly in people with diabetes or prior kidney problems). </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Considerations</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-8"><p>If a blockage is found, your cardiologist may perform a percutaneous coronary intervention (PCI) to open the blockage. This can be done during the same procedure, but may be delayed for various reasons. </p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-Alt"><p>Cardiac angiography; Angiography - heart; Angiogram - coronary; Coronary artery disease - angiography; CAD - angiography; Angina - angiography; Heart disease - angiography</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div name="Images" class="section-body" id="section-tnails"><ul class="img-grid group">
<li><img src="//medlineplus.gov/ency/images/ency/tnails/18129t.jpg" alt="Coronary angiography" title="Coronary angiography" class="side-img"/><a href="../imagepages/18129.htm">Coronary angiography</a></li>
</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-Ref"><p>Dangas GD, Mehran R. Coronary angiography and intravascular imaging. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. <em>Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine</em>. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 21.</p><p>Lange RA, Mukherjee D. Acute coronary syndrome: unstable angina and non-ST elevation myocardial infarction. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 57.</p><p>Teirstein PS, Kirtane AJ. Interventional diagnosis and treatment of coronary artery disease. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 59.</p><p>Virani SS, Newby LK, Arnold SV, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the management of patients with chronic coronary disease: A report of the American Heart Association/American College of Cardiology joint committee on clinical practice guidelines. <em>Circulation</em>. 2023;148:e9e119. PMID: 37471501 <a href="https://pubmed.ncbi.nlm.nih.gov/37471501/" target="_blank">pubmed.ncbi.nlm.nih.gov/37471501/</a>.</p></div></div></section>
<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 1/1/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div>
<div id="section-version" class="section-body"><p>Updated by: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Internal review and update on 02/19/2024 by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
</div></div></section><section><div class="section ency-citation"><div class="section-header"><div class="section-title ency-citation"><div id="citation-how-to"><button><span>Learn how to cite this page</span></button></div></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Related MedlinePlus Health Topics</h2></div><div class="section-button"><button type="submit" aria-controls="section-mtp" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div name="Related MedlinePlus Health Topics" class="section-body" id="section-mtp"><ul class="side-nav"><li><a href="https://medlineplus.gov/angina.html">Angina</a></li>
<li><a href="https://medlineplus.gov/coronaryarterydisease.html">Coronary Artery Disease</a></li>
<li><a href="https://medlineplus.gov/hearthealthtests.html">Heart Health Tests</a></li>
</ul></div></div></section></div></div></article>
</div>
<footer>
<div class="provider-box group">
<div class="urac-logo">
<a href="https://accreditnet.urac.org/directory/#/certification/HCP-2/info"><img src="https://medlineplus.gov/images/CertifiedSeal.png"/></a>
<p class="urac-logo-info">Health Content Provider<br>06/01/2025</p>
</div>
<p class="adam-info">
<a href='javascript:urac_open();'>A.D.A.M., Inc. is accredited by URAC</a>, for Health Content Provider (www.urac.org). URAC's <a href='javascript:hwsopen();'>accreditation program</a> is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s <a href='javascript:edpolopen();'>editorial policy, editorial process</a>, and <a href='javascript:ppopen();'>privacy policy</a>. A.D.A.M. is also a founding member of Hi-Ethics. This site complies with the HONcode standard for trustworthy health information: <a href='javascript:honc_open();'>verify here</a>.
</p>
</div>
<p class="adam-info">
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997-2025 A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
</p>
<div class="adam-logo">
<a href="https://www.adam.com/about" target="_blank"><img width="49" height="10" alt="About A.D.A.M." src="https://medlineplus.gov/ency/images/ency/ftrAdamlogo.gif"/></a>
</div>
<div id="mplus-footer">
<div class="footer1">
<ul class="secondarynav">
<li><a href="https://medlineplus.gov/about/">About MedlinePlus</a></li>
<li><a href="https://medlineplus.gov/whatsnew/">What's New</a></li>
<li><a href="https://medlineplus.gov/sitemap.html">Site Map</a></li>
<li><a name="contact" target="_blank" href="https://support.nlm.nih.gov/knowledgebase/category/?id=CAT-01231&amp;category=medlineplus&amp;from="><span>Customer Support</span></a></li>
</ul>
<ul class="follow-footer">
<li><a href="https://medlineplus.gov/rss.html" class="follow-item">Subscribe to RSS<img src="https://medlineplus.gov/images/feed.png" class="social-media-toolkit-icon" alt="RSS" title="RSS"></a></li>
<li><span class="follow-label">Follow us</span>
<a href="https://twitter.com/medlineplus" class="follow-item" target="_blank"><img src="https://medlineplus.gov/images/i_share_twitter.png" class="follow-icon" alt="X" title="X"></a>
<a href="https://facebook.com/Mplus.gov/" class="follow-item" target="_blank"><img src="https://medlineplus.gov/images/i_share_fb.png" class="follow-icon" alt="Facebook" title="Facebook"></a>
<a href="https://www.instagram.com/mplusgov/" class="follow-item" target="_blank"><img src="https://medlineplus.gov/images/Instagram_Glyph_Gradient_RGB.png" class="follow-icon" alt="Instagram" title="Instagram"></a>
</li>
<li><a href="https://medlineplus.gov/social-media-toolkit/" class="social-media-toolkit-item">Social Media Toolkit<img src="https://medlineplus.gov/images/i_social_media_toolkit.png" class="social-media-toolkit-icon" alt="Social Media Toolkit" title="Social Media Toolkit"></a></li>
</ul>
</div>
<div class="footer2">
<ul>
<li><a href="https://www.nlm.nih.gov/web_policies.html" target="_blank">NLM Web Policies</a></li>
<li><a href="https://medlineplus.gov/about/using/usingcontent/" >Copyright</a></li>
<li><a href="//medlineplus.gov/accessibility.html">Accessibility</a></li>
<li><a href="https://medlineplus.gov/about/using/criteria/">Guidelines for Links</a></li>
<li><a href="//medlineplus.gov/plugins.html">Viewers &amp; Players</a></li>
<li><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" target="_blank">HHS Vulnerability Disclosure</a></li>
<li><a href="https://medlineplus.gov/medlineplus-connect/">MedlinePlus Connect for EHRs</a></li>
<li><a href="https://medlineplus.gov/about/developers/">For Developers</a></li>
</ul>
<div class="address">
<a href="//www.nlm.nih.gov" target="_blank">National Library of Medicine</a>
<span>8600 Rockville Pike, Bethesda, MD 20894</span>
<a href="//www.hhs.gov" target="_blank">U.S. Department of Health and Human Services</a>
<a href="//www.nih.gov" target="_blank">National Institutes of Health</a>
</div>
<div class="return-top"><a href="#top" title="Return to top"><img class="return-top-icon" alt="Return to top" src="https://medlineplus.gov/images/return-top.png"></a></div>
</div>
</div>
</footer>
</div><!-- End Wrap -->
<script src="https://medlineplus.gov/jslib/jquery-3.6.0.min.js" type="text/javascript">
</script>
<script src="https://medlineplus.gov/jslib/mplus-frontend-controls.js" type="text/javascript">
</script>
<!--[if lte IE 9]>
<script src="https://medlineplus.gov/jslib/jquery.placeholder.js" type="text/javascript"></script>
<![endif]-->
<script src="https://medlineplus.gov/jslib/mplus-share.js?id=1112022" type="text/javascript">
</script>
<script src="https://medlineplus.gov/jslib/control.js" type="text/javascript">
</script>
<script src="https://medlineplus.gov/uswds/js/uswds.min.js" type="text/javascript">
</script>
<script src="https://medlineplus.gov/jslib/ency/ency.js" type="text/javascript">
</script>
</body>
</html>