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</div><div><span>Muscle function loss</span></div></div>
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</a><h1 class="with-also" itemprop="name">Muscle function loss</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Muscle function loss is when a muscle does not work or move normally. The medical term for complete loss of muscle function is paralysis.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Considerations</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Loss of muscle function may be caused by:</p><ul><li>A disease of the muscle itself (myopathy)</li><li>A disease of the area where the muscle and nerve meet (neuromuscular junction)</li><li>A disease of the nervous system: Nerve damage (neuropathy), spinal cord injury (myelopathy), or brain damage (<a test="test" href="./000726.htm">stroke</a> or other brain injury) </li></ul><p>The loss of muscle function after some of these types of events can be severe. In some cases, muscle strength may not completely return, even with treatment.</p><p>Paralysis can be temporary or permanent. It can affect a small area (localized or focal) or be widespread (generalized). It may affect one side (unilateral) or both sides (bilateral).</p><p>If the paralysis affects the lower half of the body and both legs it is called paraplegia. If it affects both arms and legs, it is called quadriplegia. If the paralysis affects the muscles that cause breathing, it is quickly life threatening.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Diseases of the muscles that cause muscle-function loss include:</p><ul><li>Alcohol-associated myopathy</li><li>Congenital myopathies (most often due to a genetic disorder)</li><li><a test="test" href="./000839.htm">Dermatomyositis</a> and <a test="test" href="./000428.htm">polymyositis</a></li><li>Drug-induced myopathy (statins, steroids)</li><li><a test="test" href="./001190.htm">Muscular dystrophy</a></li></ul><p>Diseases of the nervous system that cause muscle function loss include:</p><ul><li><a test="test" href="./000688.htm">Amyotrophic lateral sclerosis</a> (ALS, or Lou Gehrig disease)</li><li><a test="test" href="./000773.htm">Bell palsy</a></li><li><a test="test" href="./000598.htm">Botulism</a></li><li><a test="test" href="./000684.htm">Guillain-Barré syndrome</a></li><li><a test="test" href="./000712.htm">Myasthenia gravis</a> or Lambert-Eaton Syndrome</li><li>Neuropathy</li><li>Paralytic <a test="test" href="./002851.htm">shellfish</a> poisoning</li><li>Periodic paralysis</li><li>Focal nerve injury</li><li><a test="test" href="./001402.htm">Polio</a> or other viruses</li><li><a test="test" href="./001066.htm">Spinal cord or brain injury</a></li><li>Stroke </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Home Care</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>Sudden loss of muscle function is a medical emergency. Get medical help right away.</p><p>After you have received medical treatment, your health care provider may recommend some of the following measures:</p><ul><li>Follow your prescribed therapy.</li><li>If the nerves to your face or head are damaged, you may have difficulty chewing and swallowing or closing your eyes. In these cases, a soft diet may be recommended. You will also need some form of eye protection, such as a patch over the eye while you are asleep.</li><li>Long-term immobility can cause serious complications. Change positions often and take care of your skin. Range-of-motion exercises may help to maintain some muscle tone.</li><li><a test="test" href="./000040.htm">Splints</a> may help prevent muscle contractures, a condition in which a muscle becomes permanently shortened. </li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Muscle paralysis always requires immediate medical attention. If you notice gradual weakening or problems with a muscle, get medical attention as soon as possible.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>What to Expect at Your Office Visit</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>The provider will perform a <a test="test" href="./002274.htm">physical exam</a> and ask questions about your medical history and symptoms, including:</p><p>Location: </p><ul><li>What part(s) of your body are affected?</li><li>Does it affect one or both sides of your body?</li><li>Did it develop in a top-to-bottom pattern (descending paralysis), or a bottom-to-top pattern (ascending paralysis)?</li><li>Do you have difficulty getting out of a chair or climbing stairs?</li><li>Do you have difficulty lifting your arm above your head?</li><li>Do you have problems extending or lifting your wrist (wrist drop)?</li><li>Do you have difficulty gripping (grasping)? </li></ul><p>Symptoms: </p><ul><li>Do you have pain?</li><li>Do you have <a test="test" href="./003206.htm">numbness</a>, <a test="test" href="./003206.htm">tingling</a>, or <a test="test" href="./003206.htm">loss of sensation</a>?</li><li>Do you have difficulty controlling your bladder or bowels?</li><li>Do you have shortness of breath?</li><li>What other symptoms do you have? </li></ul><p>Time pattern: </p><ul><li>Do episodes occur repeatedly (recurrent)?</li><li>How long do they last?</li><li>Is the muscle function loss getting worse (progressive)?</li><li>Is it progressing slowly or quickly?</li><li>Does it become worse over the course of the day? </li></ul><p>Aggravating and relieving factors: </p><ul><li>What, if anything, makes the paralysis worse?</li><li>Does it get worse after you take potassium supplements or other medicines?</li><li>Is it better after you rest? </li></ul><p>
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Tests that may be performed include:</p><ul><li>Blood tests (such as <a test="test" href="./003642.htm">CBC</a>, <a test="test" href="./003657.htm">white blood cell differential</a>, blood chemistry levels, and muscle enzyme levels)</li><li><a test="test" href="./003786.htm">CT scan of the head</a> or spine</li><li><a test="test" href="./003791.htm">MRI of the head</a> or spine</li><li>Lumbar puncture (spinal tap)</li><li>Muscle or nerve <a test="test" href="./003416.htm">biopsy</a></li><li>
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Myelography
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</li><li>Muscle ultrasound</li><li>Nerve conduction studies and <a test="test" href="./003929.htm">electromyography</a></li></ul><p><a test="test" href="./002383.htm">Intravenous</a> feeding or feeding tubes may be required in severe cases. Physical therapy, occupational therapy, or speech therapy may be recommended.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Paralysis; Paresis; Loss of movement; Motor dysfunction</p></div></div></section><section><div class="section sec-mb"><div class="section-header"><div class="section-title"><h2>Images</h2></div><div class="section-button"><button type="submit" aria-controls="section-tnails" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/9678t.jpg" alt="Superficial anterior muscles" title="Superficial anterior muscles" class="side-img"/><a href="../imagepages/9678.htm">Superficial anterior muscles</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/9676t.jpg" alt="Deep anterior muscles" title="Deep anterior muscles" class="side-img"/><a href="../imagepages/9676.htm">Deep anterior muscles</a></li>
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<li><img src="//medlineplus.gov/ency/images/ency/tnails/8956t.jpg" alt="Tendons and muscles" title="Tendons and muscles" class="side-img"/><a href="../imagepages/8956.htm">Tendons and muscles</a></li>
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</ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Kaminski HJ. Disorders of neuromuscular transmission. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 390.</p><p>Selcen D. Muscle diseases. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine</em>. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 389.</p><p>Warner WC, Sawyer JR. Neuromuscular disorders. In: Azar FM, Beaty JH, eds. <em>Campbell's Operative Orthopaedics.</em> 14th ed. Philadelphia, PA: Elsevier; 2021:chap 35.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 3/31/2024</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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