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</div><div><span>Yaws</span></div></div>
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<article><div id="d-article"><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also" itemprop="name">Yaws</h1>
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</noscript></div><div class="main"><div id="ency_summary"><p>Yaws is a long-term (chronic) bacterial infection that mainly affects the skin, bones, and joints.</p></div><section><div class="section"><div class="section-header"><div class="section-title"><h2>Causes</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Yaws is an infection caused by a form of the <em>Treponema pallidum</em> bacteria. It is closely related to the bacterium that causes syphilis, but this form of the bacterium is not sexually transmitted. Yaws mainly affects children in rural, warm, tropical areas, such as, Africa, Western Pacific islands, and Southeast Asia.</p><p>Yaws is transmitted by direct contact with the skin sores of infected people.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Symptoms</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>About 2 to 4 weeks after infection, the person develops a sore called a "mother yaw" where bacteria enter the skin. The sore may be tan or reddish and looks like a raspberry. It is most often painless, but does cause itching. </p><p>The sores may last for months. More sores may appear shortly before or after the mother yaw heals. Scratching the sore can spread the bacteria from the mother yaw to uninfected skin. Eventually, the skin sores heal.</p><p>Other symptoms include:</p><ul><li><a test="test" href="./003180.htm">Bone pain</a></li><li>
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Scarring of the skin
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</li><li><a test="test" href="./003103.htm">Swelling</a> of the bones and fingers
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</li></ul><p>In the advanced stage, sores on the skin and bones can lead to severe disfigurement and disability. This occurs in up to 1 in 5 people who do not get antibiotic treatment.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Exams and Tests</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>A sample from a skin sore is examined under a special type of microscope (darkfield examination). </p><p>There is no blood test for yaws. However, the blood test for <a test="test" href="./000861.htm">syphilis</a> is often positive in people with yaws because the bacteria that cause these two conditions are closely related.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Treatment</h2></div><div class="section-button"><button type="submit" aria-controls="section-4" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-4"><p>Treatment involves a single dose of penicillin, or 3 weekly doses for later stage disease. It is rare for the disease to return. </p><p>People who live in the same house with someone who is infected should be examined for yaws and treated if they are infected.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Outlook (Prognosis)</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>If treated in its early stages, yaws can be cured. Skin lesions may take several months to heal.</p><p>By its late stage, yaws may have already caused damage to the skin and bones. It may not be fully reversible, even with treatment.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Possible Complications</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-6"><p>Yaws may damage the skin and bones. It can affect a person's appearance and ability to move. It can also cause deformities of the legs, nose, palate, and upper jaw.</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>When to Contact a Medical Professional</h2></div><div class="section-button"><button type="submit" aria-controls="section-7" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-7"><p>Contact your health care provider if:</p><ul><li>You or your child has sores on the skin or bone that don't go away. </li><li>You have stayed in tropical areas where yaws is known to occur.</li></ul></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>Alternative Names</h2></div><div class="section-button"><button type="submit" aria-controls="section-Alt" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Alt"><p>Frambesia tropica</p></div></div></section><section><div class="section"><div class="section-header"><div class="section-title"><h2>References</h2></div><div class="section-button"><button type="submit" aria-controls="section-Ref" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-Ref"><p>Dionne JA, Ghanem KG. Syphilis and nonsyphilitic treponematoses. In: Goldman L, Cooney KA, eds. <em>Goldman-Cecil Medicine.</em> 27th ed. Philadelphia, PA: Elsevier; 2024:chap 295.</p><p>Obaro SK, Davies HD. Nonvenereal treponemal infections. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. <em>Nelson Textbook of Pediatrics.</em> 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 265.</p></div></div></section>
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<section><div class="section"><div class="section-header"><div class="section-title"><h2>Review Date 12/31/2023</h2></div><div class="section-button"><button type="submit" aria-controls="section-version" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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<div id="section-version" class="section-body"><p>Updated by: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.</p>
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