nih-gov/medlineplus.gov/druginfo/meds/a682549.html
2025-02-26 13:17:41 -05:00

135 lines
No EOL
30 KiB
HTML
Raw Permalink Blame History

This file contains ambiguous Unicode characters

This file contains Unicode characters that might be confused with other characters. If you think that this is intentional, you can safely ignore this warning. Use the Escape button to reveal them.

<!DOCTYPE html>
<html lang="en" id="medmono" class="nojs us" data-root="https://medlineplus.gov"><head><meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"/><meta http-equiv="window-target" content="_top"/><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"/><meta charset="utf-8"/><meta property="fb:app_id" content="1042245625821448"/><meta name="expires" content="2025-03-08T12:59:27+05:00"/><meta name="ac-dictionary" content="medlineplus-ac-dictionary"/><link rel="shortcut icon" href="https://medlineplus.gov/images/favicon.ico" type="image/x-icon"/><meta name="viewport" content="width=device-width, initial-scale=1"/><link rel="stylesheet" href="https://medlineplus.gov/css/common_new.css?tk=1682610665830"/><link rel="stylesheet" href="https://medlineplus.gov/uswds/css/uswds_styles.css?tk=121212"/><!--[if IE 8]> <link rel="stylesheet" href="https://medlineplus.gov/css/ie8/common.css"> <![endif]--><link rel="stylesheet" href="https://medlineplus.gov/css/drug.css"/><!--[if IE 8]> <link rel="stylesheet" href="https://medlineplus.gov/css/ie8/drug_ie8.css"> <![endif]--><script type="text/javascript">document.querySelector("html").className = document.querySelector("html").className.replace(/nojs[\s]*/g, '');</script><script src="https://medlineplus.gov/uswds/js/uswds-init.min.js" type="text/javascript">
</script><script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&amp;l='+l:'';j.async=true;j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-MMVM77');</script><link rel="canonical" href="https://medlineplus.gov/druginfo/meds/a682549.html"/><meta name="description" content="Fludrocortisone Acetate: learn about side effects, dosage, special precautions, and more on MedlinePlus"/><meta property="og:description" content="Fludrocortisone Acetate: learn about side effects, dosage, special precautions, and more on MedlinePlus"/><meta property="twitter:description" content="Fludrocortisone Acetate: learn about side effects, dosage, special precautions, and more on MedlinePlus"/><meta property="og:title" content="Fludrocortisone Acetate: MedlinePlus Drug Information"/><meta property="og:url" content="https://medlineplus.gov/druginfo/meds/a682549.html"/><meta property="twitter:title" content="Fludrocortisone Acetate: MedlinePlus Drug Information"/><meta name="twitter:card" content="summary_large_image"/><meta property="og:image" content="https://medlineplus.gov/images/share_drugs_1.jpg"/><meta property="og:image" content="https://medlineplus.gov/images/share_drugs_2.jpg"/><meta property="twitter:image" content="https://medlineplus.gov/images/share_drugs_1.jpg"/><meta name="twitter:site" content="@medlineplus"/><meta content="@medlineplus" name="twitter:creator"/><link href="https://medlineplus.gov/druginfo/meds/a682549.html" hreflang="en" rel="alternate"/><link href="https://medlineplus.gov/spanish/druginfo/meds/a682549-es.html" hreflang="es" rel="alternate"/><title>Fludrocortisone Acetate: MedlinePlus Drug Information</title></head><body><!-- Google Tag Manager --><noscript><iframe title="googletagmanager" src="//www.googletagmanager.com/ns.html?id=GTM-MMVM77" height="0" width="0" style="display:none;visibility:hidden">
</iframe>
</noscript><a name="top" id="top">
</a><a class="hide-offscreen" href="#start">Skip navigation</a><section class="usa-banner" aria-label="Official website of the United States government"><div class="usa-accordion"><header class="usa-banner__header"><div class="usa-banner__inner"><div class="grid-col-auto"><img aria-hidden="true" class="usa-banner__header-flag" src="https://medlineplus.gov/uswds/img/us_flag_small.png" alt=""/>
</div><div class="grid-col-fill tablet:grid-col-auto" aria-hidden="true"><p class="usa-banner__header-text">
An official website of the United States government
</p><p class="usa-banner__header-action">Heres how you know</p></div><button type="button" class="usa-accordion__button usa-banner__button" aria-expanded="false" aria-controls="gov-banner-default-default"><span class="usa-banner__button-text">Heres how you know</span></button></div></header><div class="usa-banner__content usa-accordion__content" id="gov-banner-default-default"><div class="grid-row grid-gap-lg"><div class="usa-banner__guidance tablet:grid-col-6"><img class="usa-banner__icon usa-media-block__img" src="https://medlineplus.gov/uswds/img/icon-dot-gov.svg" role="img" alt="" aria-hidden="true"/><div class="usa-media-block__body"><p><strong>Official websites use .gov</strong><br/>A
<strong>.gov</strong> website belongs to an official government organization in the United States.
</p></div></div><div class="usa-banner__guidance tablet:grid-col-6"><img class="usa-banner__icon usa-media-block__img" src="https://medlineplus.gov/uswds/img/icon-https.svg" role="img" alt="" aria-hidden="true"/><div class="usa-media-block__body"><p><strong>Secure .gov websites use HTTPS</strong><br/>A
<strong>lock</strong> (
<span class="icon-lock"><svg xmlns="http://www.w3.org/2000/svg" width="52" height="64" viewBox="0 0 52 64" class="usa-banner__lock-image" role="img" aria-labelledby="banner-lock-description-default" focusable="false"><title id="banner-lock-title-default">Lock</title><desc id="banner-lock-description-default">Locked padlock icon</desc><path fill="#000000" fill-rule="evenodd" d="M26 0c10.493 0 19 8.507 19 19v9h3a4 4 0 0 1 4 4v28a4 4 0 0 1-4 4H4a4 4 0 0 1-4-4V32a4 4 0 0 1 4-4h3v-9C7 8.507 15.507 0 26 0zm0 8c-5.979 0-10.843 4.77-10.996 10.712L15 19v9h22v-9c0-6.075-4.925-11-11-11z">
</path></svg></span>) or <strong>https://</strong> means youve safely connected to the .gov website. Share sensitive information only on official, secure websites.
</p></div></div></div></div></div></section><!-- End Google Tag Manager --><div id="mplus-wrap"><header><div id="mplus-header"><div id="mplus-orgs"><a href="http://www.nih.gov/" class="nih-org" target="_blank" title="National Institutes of Health"><img class="nihlogo" src="https://medlineplus.gov/images/nihlogo.png" alt="National Institutes of Health"/>
</a><a href="https://www.nlm.nih.gov/" target="_blank"> National Library of Medicine</a></div><div id="mplus-logo" class="years-25"><a href="https://medlineplus.gov/"><img alt="MedlinePlus Trusted Health Information for You" title="MedlinePlus Trusted Health Information for You" src="https://medlineplus.gov/images/m_logo_25.png"/>
</a>
</div><div id="mplus-nav"><div aria-live="polite" class="sm-live-area hide-offscreen">
</div><button id="sm-menu-btn" class="navmenu-btn" title="Menu" role="button" aria-controls="mplus-menu-list" type="submit">Menu<span class="icon icon-nav-menu">
</span></button><ul id="mplus-menu-list" class="nav-list"><li><a href="https://medlineplus.gov/healthtopics.html">Health Topics</a></li><li><a href="https://medlineplus.gov/druginformation.html">Drugs &amp; Supplements</a></li><li><a href="https://medlineplus.gov/genetics/">Genetics</a></li><li><a href="https://medlineplus.gov/lab-tests/">Medical Tests</a></li><li><a href="https://medlineplus.gov/encyclopedia.html">Medical Encyclopedia</a></li><li><a href="https://medlineplus.gov/about/">About MedlinePlus</a></li></ul><button id="sm-search-btn" class="navmenu-btn" title="Search" role="button" aria-controls="mplus-search" type="submit"><span class="hide-offscreen">
</span>Search<span class="icon icon-nav-search">
</span></button><div class="top-1"><form id="mplus-search" method="get" action="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta" title="Search MedlinePlus" target="_self"><input type="hidden" name="v:project" value="medlineplus"/><input type="hidden" name="v:sources" value="medlineplus-bundle"/><div class="form-box text-combo"><div class="form-area"><label class="hide-offscreen" for="searchtext_primary">Search MedlinePlus</label><input id="searchtext_primary" class="form-text" type="text" placeholder="Search MedlinePlus" alt="#Site Search input" title="Site Search input" maxlength="400" size="40" name="query" autocomplete="off" role="textbox" aria-autocomplete="list" aria-haspopup="true"/></div><div class="button-area"><button class="form-btn" title="Search MedlinePlus" alt="Search MedlinePlus" type="submit">GO</button></div></div></form><div class="secondarynav"><ul class="nav-list"><li><a href="https://medlineplus.gov/about/"><span>About MedlinePlus</span></a></li><li><a href="https://medlineplus.gov/whatsnew/">What's New</a></li><li><a href="https://medlineplus.gov/sitemap.html"><span>Site Map</span></a></li><li><a href="https://support.nlm.nih.gov/knowledgebase/category/?id=CAT-01231&amp;category=medlineplus&amp;from=https%3A//medlineplus.gov/skincancer.html" target="_blank"><span>Customer Support</span></a></li></ul></div></div><div id="mplus-nav-bar"><ul class="nav-list"><li><a href="https://medlineplus.gov/healthtopics.html">Health Topics</a></li><li><a href="https://medlineplus.gov/druginformation.html">Drugs &amp; Supplements</a></li><li><a href="https://medlineplus.gov/genetics/">Genetics</a></li><li><a href="https://medlineplus.gov/lab-tests/">Medical Tests</a></li><li><a href="https://medlineplus.gov/encyclopedia.html">Medical Encyclopedia</a></li></ul></div><a title="Español" id="mplus-lang-toggle" href="../../spanish/druginfo/meds/a682549-es.html">Español</a></div></div></header><div id="mplus-content"><!-- Breadrcumbs --><div id="breadcrumbs"><div itemtype="http://schema.org/BreadcrumbList" itemscope="" itemprop="breadcrumb"><span class="hide-offscreen">You Are Here:</span>
<div itemscope itemprop="itemListElement" itemtype="http://schema.org/ListItem">
<a href="https://medlineplus.gov" itemprop="item"><span itemprop="name">Home</span></a>
&rarr;
<meta itemprop="position" content="1"/>
</div>
<div itemscope itemprop="itemListElement" itemtype="http://schema.org/ListItem">
<a href="https://medlineplus.gov/druginformation.html" itemprop="item"><span itemprop="name">Drugs, Herbs and Supplements</span></a>
&rarr;
<meta itemprop="position" content="2"/>
</div>
</div><div><span>Fludrocortisone Acetate</span></div></div><span class="page-url print-only">URL of this page: https://medlineplus.gov/druginfo/meds/a682549.html</span><!-- Article --><article><div class="page-info"><div class="page-title"><a name="start" id="start">
</a><h1 class="with-also">Fludrocortisone Acetate</h1><span class="alsocalled" id="d-pronunciation">pronounced as (floo droe kor' ti sone)
</span>
</div><div class="page-actions">
</div>
<noscript><span class="js-disabled-message">To use the sharing features on this page, please enable JavaScript.</span></noscript></div><div id="toc-box"><ul role="navigation" class="group"><li><a href="#why">Why is this medication prescribed?</a>
</li><li><a href="#how">How should this medicine be used?</a>
</li><li><a href="#other-uses">Other uses for this medicine</a>
</li><li><a href="#precautions">What special precautions should I follow?</a>
</li><li><a href="#special-dietary">What special dietary instructions should I follow?</a>
</li><li><a href="#if-i-forget">What should I do if I forget a dose?</a>
</li><li><a href="#side-effects">What side effects can this medication cause?</a>
</li><li><a href="#storage-conditions">What should I know about storage and disposal of this medication?</a>
</li><li><a href="#overdose">In case of emergency/overdose</a>
</li><li><a href="#other-information">What other information should I know?</a>
</li><li><a href="#brand-name-1">Brand names</a>
</li></ul></div><section><div id="why" class="section"><div class="section-header"><div class="section-title"><h2>Why is this medication prescribed?</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-1"><p>Fludrocortisone, a corticosteroid, is used to help control the amount of sodium and fluids in your body. It is used to treat Addison's disease and syndromes where excessive amounts of sodium are lost in the urine. It works by decreasing the amount of sodium that is lost (excreted) in your urine.</p><p>This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.</p></div></div></section><section><div id="how" class="section"><div class="section-header"><div class="section-title"><h2>How should this medicine be used?</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-2"><p>Fludrocortisone comes as a tablet to be taken by mouth. Your doctor will prescribe a dosing schedule that is best for you. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take fludrocortisone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.</p><p>Do not stop taking fludrocortisone without talking to your doctor. Stopping the drug abruptly can cause loss of appetite, an upset stomach, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss. If you take large doses for a long time, your doctor probably will decrease your dose gradually to allow your body to adjust before stopping the drug completely. Watch for these side effects if you are gradually decreasing your dose and after you stop taking the tablets. If these problems occur, call your doctor immediately. You may need to increase your dose temporarily or start taking the tablets again.</p></div></div></section><section><div id="other-uses" class="section"><div class="section-header"><div class="section-title"><h2>Other uses for this medicine</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-3"><p>Fludrocortisone is also used to increase blood pressure. Talk to your doctor about the possible risks of using this drug for your condition.</p></div></div></section><section><div id="precautions" class="section"><div class="section-header"><div class="section-title"><h2>What special precautions should I follow?</h2></div><div class="section-button"><button type="submit" aria-controls="section-precautions" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-precautions"><h3>Before taking fludrocortisone,</h3><ul><li>tell your doctor and pharmacist if you are allergic to fludrocortisone, aspirin, tartrazine (a yellow dye in some processed foods and drugs), or any other drugs.</li><li>tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking fludrocortisone. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.</li><li>if you have a fungal infection (other than on your skin), do not take fludrocortisone without talking to your doctor.</li><li>tell your doctor if you have or have ever had liver, kidney, intestinal, or heart disease; diabetes; an underactive thyroid gland; high blood pressure; mental illness; myasthenia gravis; osteoporosis; herpes eye infection; seizures; tuberculosis (TB); or ulcers.</li><li>tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking fludrocortisone, call your doctor.</li><li>if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking fludrocortisone.</li><li>if you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit your consumption of alcoholic beverages while taking this drug. Fludrocortisone makes your stomach and intestines more susceptible to the irritating effects of alcohol, aspirin, and certain arthritis medications. This effect increases your risk of ulcers.</li></ul></div></div></section><section><div id="special-dietary" class="section"><div class="section-header"><div class="section-title"><h2>What special dietary instructions should I follow?</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-5"><p>Your doctor may instruct you to follow a low-sodium, low-salt, potassium-rich, or high-protein diet. Follow these directions.</p><p>Fludrocortisone may cause an upset stomach. Take fludrocortisone with food or milk.</p></div></div></section><section><div id="if-i-forget" class="section"><div class="section-header"><div class="section-title"><h2>What should I do if I forget a dose?</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-6"><p>When you start to take fludrocortisone, ask your doctor what to do if you forget a dose. Write down these instructions so that you can refer to them later.</p><p>If you take fludrocortisone once a day, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.</p></div></div></section><section><div id="side-effects" class="section"><div class="section-header"><div class="section-title"><h2>What side effects can this medication cause?</h2></div><div class="section-button"><button type="submit" aria-controls="section-side-effects" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-side-effects"><h3>Fludrocortisone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
</h3><ul><li>upset stomach</li><li>stomach irritation</li><li>vomiting</li><li>headache</li><li>dizziness</li><li>insomnia</li><li>restlessness</li><li>depression</li><li>anxiety</li><li>acne</li><li>increased hair growth</li><li>easy bruising</li><li>irregular or absent menstrual periods</li></ul><h3>If you experience any of the following symptoms, call your doctor immediately:
</h3><ul><li>skin rash</li><li>swollen face, lower legs, or ankles</li><li>vision problems</li><li>cold or infection that lasts a long time</li><li>muscle weakness</li><li>black or tarry stool</li></ul><p>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (<a target="_blank" href="https://www.fda.gov/Safety/MedWatch">https://www.fda.gov/Safety/MedWatch</a>) or by phone (1-800-332-1088).</p></div></div></section><section><div id="storage-conditions" class="section"><div class="section-header"><div class="section-title"><h2>What should I know about storage and disposal of this medication?</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-8"><p>Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).</p><p>Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (<a target="_blank" href="https://goo.gl/c4Rm4p">https://goo.gl/c4Rm4p</a>) for more information if you do not have access to a take-back program.</p><p>It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. <a target="_blank" href="https://www.upandaway.org">https://www.upandaway.org</a></p></div></div></section><section><div id="overdose" class="section"><div class="section-header"><div class="section-title"><h2>In case of emergency/overdose</h2></div><div class="section-button"><button type="submit" aria-controls="section-9" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-9"><p>In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at <a target="_blank" href="https://www.poisonhelp.org/help">https://www.poisonhelp.org/help</a>. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.</p></div></div></section><section><div id="other-information" class="section"><div class="section-header"><div class="section-title"><h2>What other information should I know?</h2></div><div class="section-button"><button type="submit" aria-controls="section-10" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-10"><p>Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to fludrocortisone. Your blood pressure should be checked regularly to determine your response to fludrocortisone.</p><p>If your condition worsens, call your doctor. Your dose may need to be adjusted.</p><p>Carry an identification card that indicates that you may need to take supplementary doses (write down the full dose you took before gradually decreasing it) of fludrocortisone during periods of stress (injuries, infections, and severe asthma attacks). Ask your pharmacist or doctor how to obtain this card. List your name, medical problems, drugs and dosages, and doctor's name and telephone number on the card.</p><p>This drug makes you more susceptible to illnesses. If you are exposed to chicken pox, measles, or tuberculosis (TB) while taking fludrocortisone, call your doctor. Do not have a vaccination, other immunization, or any skin test while you are taking fludrocortisone unless your doctor tells you that you may.</p><p>Report any injuries or signs of infection (fever, sore throat, pain during urination, and muscle aches) that occur during treatment.</p><p>Your doctor may instruct you to weigh yourself every day. Report any unusual weight gain.</p><p>If your sputum (the matter you cough up during an asthma attack) thickens or changes color from clear white to yellow, green, or gray, call your doctor; these changes may be signs of an infection.</p><p>If you have diabetes, fludrocortisone may increase your blood sugar level. If you monitor your blood sugar (glucose) at home, test your blood or urine more frequently than usual. Call your doctor if your blood sugar is high or if sugar is present in your urine; your dose of diabetes medication and your diet may need to be changed.</p><p>Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.</p><p>It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.</p></div></div></section><section><div id="brand-name-1" class="section"><div class="section-header"><div class="section-title"><h2>Brand names</h2></div><div class="section-button"><button type="submit" aria-controls="section-brandname-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-brandname-1"><ul><li>Florinef<sup>®</sup></li></ul></div></div></section><span>Last Revised - </span><span>08/15/2017</span>
</p>
<div id="bdme"><a href="https://medlineplus.gov/druginformation.html">Browse Drugs and Medicines</a></div><div id="citation-how-to"><button><span>Learn how to cite this page</span></button></div></article></div><footer><div class="provider-box"><img src="https://medlineplus.gov/images/ashpTM_CMYK_small.jpg" alt="ASHP Logo" title="ASHP Logo"/><a href="https://medlineplus.gov/ashpdisclaimer.html">American Society of Health-System Pharmacists, Inc. Disclaimer</a><div><p>AHFS<sup>®</sup> Patient Medication Information™. © Copyright, 2024. The American Society of Health-System Pharmacists<sup>®</sup>, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.</p></div></div>
<div id="mplus-footer">
<div class="footer1">
<ul class="secondarynav">
<li><a href="https://medlineplus.gov/about/">About MedlinePlus</a></li>
<li><a href="https://medlineplus.gov/whatsnew/">What's New</a></li>
<li><a href="https://medlineplus.gov/sitemap.html">Site Map</a></li>
<li><a target="_blank" href="https://support.nlm.nih.gov/knowledgebase/category/?id=CAT-01231&amp;category=medlineplus&amp;from="><span>Customer Support</span></a></li>
</ul>
<ul class="follow-footer">
<li>
<a href="https://medlineplus.gov/rss.html" class="follow-item">Subscribe to RSS<img src="https://medlineplus.gov/images/feed.png" class="social-media-toolkit-icon" alt="RSS" title="RSS"></a>
</li>
<li>
<span class="follow-label">Follow us</span>
<a href="https://twitter.com/medlineplus" class="follow-item" target="_blank">
<img src="https://medlineplus.gov/images/i_share_twitter.png" class="follow-icon" alt="X" title="X">
</a>
<a href="https://facebook.com/Mplus.gov/" class="follow-item" target="_blank">
<img src="https://medlineplus.gov/images/i_share_fb.png" class="follow-icon" alt="Facebook" title="Facebook">
</a>
<a href="https://www.instagram.com/mplusgov/" class="follow-item" target="_blank">
<img src="https://medlineplus.gov/images/Instagram_Glyph_Gradient_RGB.png" class="follow-icon" alt="Instagram" title="Instagram">
</a>
</li>
<li>
<a href="https://medlineplus.gov/social-media-toolkit/" class="social-media-toolkit-item">Social Media Toolkit<img src="https://medlineplus.gov/images/i_social_media_toolkit.png" class="social-media-toolkit-icon" alt="Social Media Toolkit" title="Social Media Toolkit"></a>
</li>
</ul>
</div>
<div class="footer2">
<ul>
<li><a href=" https://www.nlm.nih.gov/web_policies.html" target='_blank'>NLM Web Policies</a></li>
<li><a href="https://medlineplus.gov/about/using/usingcontent/" >Copyright</a></li>
<li><a href="https://medlineplus.gov/accessibility.html">Accessibility</a></li>
<li><a href="https://medlineplus.gov/about/using/criteria/">Guidelines for Links</a></li>
<li><a href="https://medlineplus.gov/plugins.html">Viewers &amp; Players</a></li>
<li><a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" target="_blank">HHS Vulnerability Disclosure</a></li>
<li><a href="https://medlineplus.gov/medlineplus-connect/">MedlinePlus Connect for EHRs</a></li>
<li><a href="https://medlineplus.gov/about/developers/">For Developers</a></li>
</ul>
<div class="address">
<a href="//www.nlm.nih.gov" target="_blank">National Library of Medicine</a>
<span>8600 Rockville Pike, Bethesda, MD 20894</span>
<a href="//www.hhs.gov" target="_blank">U.S. Department of Health and Human Services</a>
<a href="//www.nih.gov" target="_blank">National Institutes of Health</a>
</div>
<div class="return-top"><a href="#top" title="Return to top"><img class="return-top-icon" alt="Return to top" src="https://medlineplus.gov/images/return-top.png"></a></div>
</div>
</div>
</footer></div><!-- End Wrap --><script src="https://medlineplus.gov/jslib/jquery-3.6.0.min.js" type="text/javascript">
</script><script src="https://medlineplus.gov/jslib/mplus-frontend-controls.js" type="text/javascript">
</script><!--[if lte IE 9]>
<script src="https://medlineplus.gov/jslib/jquery.placeholder.js" type="text/javascript"></script>
<![endif]--><script src="https://medlineplus.gov/jslib/mplus-share.js?id=1112022" type="text/javascript">
</script><script src="https://medlineplus.gov/jslib/control.js" type="text/javascript">
</script><script src="https://medlineplus.gov/uswds/js/uswds.min.js" type="text/javascript">
</script><script src="https://medlineplus.gov/jslib/drug.js" type="text/javascript">
</script></body></html>