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</div><div><span>Gadolinium-based Contrast Agents</span></div></div><span class="page-url print-only">URL of this page: https://medlineplus.gov/druginfo/meds/a624076.html</span><!-- Article --><article><div class="page-info"><div class="page-title"><a name="start" id="start">
</a><h1 class="with-also">Gadolinium-based Contrast Agents</h1><span class="alsocalled" id="d-pronunciation">pronounced as (ga
duh
nee
uhm)
</span>
</div><div class="page-actions">
</div>
<noscript><span class="js-disabled-message">To use the sharing features on this page, please enable JavaScript.</span></noscript></div><div id="toc-box"><ul role="navigation" class="group"><li><a href="#why">Why is this medication prescribed?</a>
</li><li><a href="#how">How should this medicine be used?</a>
</li><li><a href="#other-uses">Other uses for this medicine</a>
</li><li><a href="#precautions">What special precautions should I follow?</a>
</li><li><a href="#side-effects">What side effects can this medication cause?</a>
</li><li><a href="#other-information">What other information should I know?</a>
</li><li><a href="#other-name">Other names</a>
</li></ul></div><section><div id="boxed-warning" class="section"><div class="section-header"><div class="section-title"><h2>IMPORTANT WARNING: </h2></div><div class="section-button"><button type="submit" aria-controls="section-warning" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-warning"><p>Gadolinium-based contrast agents (GBCAs) may cause problems with your skin, muscles, and other organs in your body.
Tell your doctor if you have or have ever had kidney problems or have previously had a magnetic resonance imaging (MRI) scan.
If you experience any of the following symptoms, call your doctor immediately: burning, itching, swelling, scaling, hardening and tightening of the skin; red or dark patches on the skin; stiffness in joints with trouble moving, bending or straightening the arms, hands, legs or feet; pain in the hip bones or ribs; or muscle weakness.</p><p>GBCAs must not be given by intrathecal (into the space around the spinal cord) injection.</p><p>Keep all appointments with your doctor and the laboratory.</p><p/><p/><p>Your healthcare provider will give you the manufacturer's patient information sheet (Medication Guide) before you begin the MRI test with a GBCA. You can also visit the Food and Drug Administration (FDA) website (<a target="_blank" href="https://www.fda.gov/Drugs/DrugSafety/ucm085729.htm">https://www.fda.gov/Drugs/DrugSafety/ucm085729.htm</a>) or the manufacturer's website to obtain the Medication Guide. </p><p>Talk to your doctor about the risks of receiving GBCAs.</p></div></div></section><section><div id="why" class="section"><div class="section-header"><div class="section-title"><h2>Why is this medication prescribed?</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-1"><p>GBCAs are used at the time of a magnetic resonance imaging (MRI; a test that creates clear images of the structures inside your body using a large magnet, radio waves and a computer) scan to allow your doctor to see images of your brain,
spine,
heart, liver, breast(s), certain blood vessels,
and other areas inside your body.
Gadolinium-based contrast agents are in a class of medications called paramagnetic contrast agents.
It works to improve the quality of the images seen by a MRI scan.</p></div></div></section><section><div id="how" class="section"><div class="section-header"><div class="section-title"><h2>How should this medicine be used?</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-2"><p> GBCAs come as a solution (liquid) to be injected into a vein at the time of your MRI scan by a healthcare provider.
Your doctor will give a dose of the medication that is best for you.</p></div></div></section><section><div id="other-uses" class="section"><div class="section-header"><div class="section-title"><h2>Other uses for this medicine</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-3"><p>This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.</p></div></div></section><section><div id="precautions" class="section"><div class="section-header"><div class="section-title"><h2>What special precautions should I follow?</h2></div><div class="section-button"><button type="submit" aria-controls="section-precautions" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-precautions"><h3>Before receiving a GBCA </h3><ul><li> tell your doctor and pharmacist if you are allergic to dyes or any GBCA, any other medications, or any of the ingredients in the injection.
Ask your pharmacist or check the Medication Guide for a list of the ingredients.</li><li> tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.</li><li>tell your doctor if you are over 60 years of age or if you have or have ever had high blood pressure, diabetes, or kidney disease.</li><li>tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.</li></ul></div></div></section><section><div id="side-effects" class="section"><div class="section-header"><div class="section-title"><h2>What side effects can this medication cause?</h2></div><div class="section-button"><button type="submit" aria-controls="section-side-effects" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-side-effects"><h3>Gadolinium-based contrast agents may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
</h3><ul><li>burning, pain, or feeling of warmth or coldness at or around the injection site</li><li>headache</li><li>nausea</li></ul><h3>Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:
</h3><ul><li>rash, itching, hives, dizziness, or difficulty breathing or swallowing</li></ul><p>GBCAs may stay in certain areas of your body such as the brain, bones, and skin in small amounts for months or years, especially if you have kidney problems.
Talk to your doctor about the risks of taking this medication.</p><p>GBCAs may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.</p><p>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (<a target="_blank" href="https://www.fda.gov/Safety/MedWatch">https://www.fda.gov/Safety/MedWatch</a>) or by phone (<a href="tel:1-800-332-1088">1-800-332-1088</a>).</p></div></div></section><section><div id="other-information" class="section"><div class="section-header"><div class="section-title"><h2>What other information should I know?</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-6"><p>Keep all appointments with your doctor.</p><p>It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.</p><p/></div></div></section><section><div id="other-name" class="section"><div class="section-header"><div class="section-title"><h2>Other names</h2></div><div class="section-button"><button type="submit" aria-controls="section-other-name" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
</div></div><div class="section-body" id="section-other-name"><ul><li>Clariscan<sup>®</sup></li><li>Dotarem<sup>®</sup></li><li>Elucirem<sup>®</sup></li><li>Eovist<sup>®</sup></li><li>Gadavist<sup>®</sup></li><li>Magnevist<sup>®</sup><a href="#discontinued"><sup></sup></a></li><li>MultiHance <sup>®</sup><a href="#discontinued"><sup></sup></a></li><li>Omniscan<sup>®</sup></li><li>OptiMark<sup>®</sup><a href="#discontinued"><sup></sup></a></li><li>Prohance<sup>®</sup></li><li>gadoterate meglumine</li><li>gadopiclenol</li><li>gadoxetate disodium</li><li>gadobutrol</li><li>gadopentetate dimeglumine</li><li>gadodiamide</li><li>gadoversetamide</li><li>gadoteridol</li></ul></div></div></section><div id="footnote"><p><sup id="discontinued"></sup> This branded product is no longer on the market. Generic alternatives may be available.</p></div><span>Last Revised - </span><span>12/15/2024</span>
</p>
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