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</div><div><span>Tasimelteon</span></div></div><span class="page-url print-only">URL of this page: https://medlineplus.gov/druginfo/meds/a615004.html</span><!-- Article --><article><div class="page-info"><div class="page-title"><a name="start" id="start">
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</a><h1 class="with-also">Tasimelteon</h1><span class="alsocalled" id="d-pronunciation">pronounced as (tas'' i mel' tee on)
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</span>
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</div><div class="page-actions">
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<noscript><span class="js-disabled-message">To use the sharing features on this page, please enable JavaScript.</span></noscript></div><div id="toc-box"><ul role="navigation" class="group"><li><a href="#why">Why is this medication prescribed?</a>
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</li><li><a href="#how">How should this medicine be used?</a>
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</li><li><a href="#other-uses">Other uses for this medicine</a>
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</li><li><a href="#precautions">What special precautions should I follow?</a>
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</li><li><a href="#special-dietary">What special dietary instructions should I follow?</a>
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</li><li><a href="#if-i-forget">What should I do if I forget a dose?</a>
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</li><li><a href="#side-effects">What side effects can this medication cause?</a>
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</li><li><a href="#storage-conditions">What should I know about storage and disposal of this medication?</a>
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</li><li><a href="#overdose">In case of emergency/overdose</a>
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</li><li><a href="#other-information">What other information should I know?</a>
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</li><li><a href="#brand-name-1">Brand names</a>
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</li></ul></div><section><div id="why" class="section"><div class="section-header"><div class="section-title"><h2>Why is this medication prescribed?</h2></div><div class="section-button"><button type="submit" aria-controls="section-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-1"><p>Tasimelteon is used to treat non-24-hour sleep-wake disorder (non-24; a condition that occurs mainly in people who are blind in which the body's natural clock is out of sync with the normal day-night cycle and causes a disrupted sleep schedule) in adults. It is also used to treat nighttime sleep problems in adults and children 3 years of age and older with Smith-Magenis Syndrome (SMS; a developmental disorder). Tasimelteon is in a class of medications called melatonin receptor agonists. It works similarly to melatonin, a natural substance in the brain that is needed for sleep.</p></div></div></section><section><div id="how" class="section"><div class="section-header"><div class="section-title"><h2>How should this medicine be used?</h2></div><div class="section-button"><button type="submit" aria-controls="section-2" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-2"><p>Tasimelteon comes as a capsule and as an suspension to take by mouth. It is usually taken without food once a day, 1 hour before bedtime. Take tasimelteon at the same time every night. If you or your child are unable to take tasimelteon around the same time on a given night, skip that dose and take the next dose as scheduled. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take tasimelteon exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.</p><p>Swallow the capsules whole; do not open, crush, or chew them.</p><h3>If you or your child are taking the suspension, follow these steps to prepare and measure the dose:
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</h3><ol><li>Remove the tasimelteon bottle, bottle adapter, and oral dosing syringe from the carton.</li><li>Shake the bottle up and down for at least 30 seconds to mix the medication evenly before each administration.</li><li>Press down on the child-resistant cap and twist it counterclockwise to open the bottle; do not discard the cap.</li><li>Before you open the tasimelteon bottle for the first time, remove the seal from bottle and insert the press-in bottle adapter into the bottle. Press on the bottle adapter until it is even with the top of the bottle; after the bottle adapter is in place, do not remove it. Then, replace the cap by turning clockwise and shake well again for 30 seconds.</li><li>Push the plunger of the oral dosing syringe completely down. Insert the oral dosing syringe into the opening of the press-in bottle adapter as far as it will go.</li><li>With the oral dosing syringe in the bottle adapter, carefully turn the bottle upside down. Pull the plunger back to withdraw the amount of suspension prescribed by the doctor. If you are not sure how to correctly measure the dose, ask your doctor or pharmacist. If you see more than a few air bubbles in the oral dosing syringe, fully push in the plunger so that the liquid flows back into the bottle until the air bubbles are mostly gone.</li><li>Leave the oral dosing syringe in the bottle adapter and turn the bottle upright. Carefully remove the oral dosing syringe from the bottle adapter. Replace the child-resistant cap securely.</li><li>Remove the dosing dispenser and slowly squirt the suspension directly into your mouth or your child's mouth and toward the inside of their cheek. Slowly push the plunger all the way in to give the entire dose. Make sure the child has time to swallow the medication.</li><li>Remove the plunger from the barrel of the oral dosing syringe. Rinse the oral dosing syringe barrel and plunger with water and when dry, put the plunger back into the oral dosing syringe. Do not wash the oral dosing syringe in the dishwasher.</li><li>Do not discard the oral dosing syringe. Always use the oral dosing syringe that comes with tasimelteon to measure your child's dose.</li><li>Refrigerate the suspension after each use.</li></ol><p>You may become sleepy soon after you take tasimelteon. After you take tasimelteon, you should complete any necessary bedtime preparations and go to bed. Do not plan any other activities for this time.</p><p>Tasimelteon controls certain sleep disorders, but does not cure them. It may take several weeks or months before you feel the full benefit of tasimelteon. Continue to take tasimelteon even if you feel well. Do not stop taking tasimelteon without talking to your doctor.</p><p>Tasimelteon is not available in pharmacies. You can only get tasimelteon through the mail from a specialty pharmacy. Ask your doctor if you have any questions about receiving your medication.</p><p>Tasimelteon capsules and suspension may not be able to be substituted for one another. Ask your pharmacist if you have any questions about the type of tasimelteon product your doctor has prescribed.</p></div></div></section><section><div id="other-uses" class="section"><div class="section-header"><div class="section-title"><h2>Other uses for this medicine</h2></div><div class="section-button"><button type="submit" aria-controls="section-3" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-3"><p>This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.</p></div></div></section><section><div id="precautions" class="section"><div class="section-header"><div class="section-title"><h2>What special precautions should I follow?</h2></div><div class="section-button"><button type="submit" aria-controls="section-precautions" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-precautions"><h3>Before taking tasimelteon,</h3><ul><li>tell your doctor and pharmacist if you are allergic to tasimelteon, any other medications, or any of the ingredients in tasimelteon capsules and suspension. Ask your pharmacist for a list of the ingredients.</li><li>tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking tasimelteon.Your doctor may need to change the doses of your medications or monitor you carefully for side effects.</li><li>tell your doctor if you have or have ever had liver disease.</li><li>tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking tasimelteon, call your doctor.</li><li>you should know that tasimelteon may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.</li><li>ask your doctor about the safe use of alcoholic beverages while you are taking tasimelteon. Alcohol can make the side effects from tasimelteon worse.</li><li>tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.</li></ul></div></div></section><section><div id="special-dietary" class="section"><div class="section-header"><div class="section-title"><h2>What special dietary instructions should I follow?</h2></div><div class="section-button"><button type="submit" aria-controls="section-5" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-5"><p>Unless your doctor tells you otherwise, continue your normal diet.</p></div></div></section><section><div id="if-i-forget" class="section"><div class="section-header"><div class="section-title"><h2>What should I do if I forget a dose?</h2></div><div class="section-button"><button type="submit" aria-controls="section-6" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</span></button></div><div class="sm-live-area hide-offscreen" aria-live="polite">
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</div></div><div class="section-body" id="section-6"><p>Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.</p></div></div></section><section><div id="side-effects" class="section"><div class="section-header"><div class="section-title"><h2>What side effects can this medication cause?</h2></div><div class="section-button"><button type="submit" aria-controls="section-side-effects" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-side-effects"><h3>Tasimelteon may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
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</h3><ul><li>headache</li><li>nightmares or unusual dreams</li><li>fever or painful, difficult, or frequent urination</li><li>fever, cough, shortness of breath, or other signs of infection</li></ul><p>Tasimelteon may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.</p><p>If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (<a target="_blank" href="https://www.fda.gov/Safety/MedWatch">https://www.fda.gov/Safety/MedWatch</a>) or by phone (1-800-332-1088).</p></div></div></section><section><div id="storage-conditions" class="section"><div class="section-header"><div class="section-title"><h2>What should I know about storage and disposal of this medication?</h2></div><div class="section-button"><button type="submit" aria-controls="section-8" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-8"><p>Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom). Refrigerate the suspension. After opening the suspension bottle, discard any unused liquid medication after 5 weeks (for the 48 mL bottle) and after 8 weeks (for the 158 mL bottle).</p><p>It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. <a target="_blank" href="https://www.upandaway.org">https://www.upandaway.org</a></p><p>Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (<a target="_blank" href="https://goo.gl/c4Rm4p">https://goo.gl/c4Rm4p</a>) for more information if you do not have access to a take-back program.</p></div></div></section><section><div id="overdose" class="section"><div class="section-header"><div class="section-title"><h2>In case of emergency/overdose</h2></div><div class="section-button"><button type="submit" aria-controls="section-9" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-9"><p>In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at <a target="_blank" href="https://www.poisonhelp.org/help">https://www.poisonhelp.org/help</a>. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.</p></div></div></section><section><div id="other-information" class="section"><div class="section-header"><div class="section-title"><h2>What other information should I know?</h2></div><div class="section-button"><button type="submit" aria-controls="section-10" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-10"><p>Keep all appointments with your doctor.</p><p>Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.</p><p>It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.</p></div></div></section><section><div id="brand-name-1" class="section"><div class="section-header"><div class="section-title"><h2>Brand names</h2></div><div class="section-button"><button type="submit" aria-controls="section-brandname-1" role="button" title="Expand/Collapse section"><span class="icon icon-section-action">
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</div></div><div class="section-body" id="section-brandname-1"><ul><li>Hetlioz<sup>®</sup></li></ul></div></div></section><span>Last Revised - </span><span>05/15/2021</span>
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</p>
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