1484 lines
98 KiB
Text
1484 lines
98 KiB
Text
<!DOCTYPE html>
|
||
<html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#">
|
||
<head>
|
||
<meta charset="utf-8" />
|
||
<meta name="description" content="Concepts under development are posted here to alert researchers to areas of NIH HEAL Initiative research interest and to give researchers maximal lead time to plan projects." />
|
||
<link rel="canonical" href="https://heal.nih.gov/funding/research-concepts" />
|
||
<link rel="image_src" href="/files/heal-logo-social.png" />
|
||
<meta property="og:site_name" content="NIH HEAL Initiative" />
|
||
<meta property="og:type" content="website" />
|
||
<meta property="og:url" content="https://heal.nih.gov/funding/research-concepts" />
|
||
<meta property="og:description" content="Concepts under development are posted here to alert researchers to areas of NIH HEAL Initiative research interest and to give researchers maximal lead time to plan projects." />
|
||
<meta property="og:image" content="https://heal.nih.gov/files/heal-logo-social.png" />
|
||
<meta property="og:image:url" content="https://heal.nih.gov/files/heal-logo-social.png" />
|
||
<meta property="og:updated_time" content="Wed, 10/23/2024 - 11:23am" />
|
||
<meta property="article:published_time" content="Tue, 11/09/2021 - 11:20am" />
|
||
<meta property="article:modified_time" content="Wed, 10/23/2024 - 11:23am" />
|
||
<meta name="twitter:card" content="summary_large_image" />
|
||
<meta name="twitter:description" content="Concepts under development are posted here to alert researchers to areas of NIH HEAL Initiative research interest and to give researchers maximal lead time to plan projects." />
|
||
<meta name="twitter:creator" content="@NIH" />
|
||
<meta name="twitter:image" content="https://heal.nih.gov/files/heal-logo-social.png" />
|
||
<meta name="Generator" content="Drupal 10 (https://www.drupal.org)" />
|
||
<meta name="MobileOptimized" content="width" />
|
||
<meta name="HandheldFriendly" content="true" />
|
||
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
||
<link rel="icon" href="/files/favicon.ico" type="image/vnd.microsoft.icon" />
|
||
<script>window.a2a_config=window.a2a_config||{};a2a_config.callbacks=[];a2a_config.overlays=[];a2a_config.templates={};</script>
|
||
|
||
<title>Research Concepts | NIH HEAL Initiative</title>
|
||
<link rel="stylesheet" media="all" href="/files/css/css_ptZvjz1DHdENmqKvZE20JWlSxsZK9VJYj5ERnyQccXA.css?delta=0&language=en&theme=particle&include=eJxFylEOwyAMA9ALATlSFZp0oKWAQlDX209IVP2zn41EVrHcgCuEQ2sxR_UqUpE2yeW7CUYWVnjUT_VLvSU-2fHPpgLpaChhVddQ8aPYUn-WV8IobUTJPTHNo-VdGPaq7PrdjU-I2PkPfHY_0g" />
|
||
<link rel="stylesheet" media="all" href="/files/css/css_Kzcx5y8_UgmvOm2su6202zfZz3qqdNhdBCeZjOratTU.css?delta=1&language=en&theme=particle&include=eJxFylEOwyAMA9ALATlSFZp0oKWAQlDX209IVP2zn41EVrHcgCuEQ2sxR_UqUpE2yeW7CUYWVnjUT_VLvSU-2fHPpgLpaChhVddQ8aPYUn-WV8IobUTJPTHNo-VdGPaq7PrdjU-I2PkPfHY_0g" />
|
||
|
||
<link rel="preconnect" href="https://fonts.gstatic.com/" crossorigin="anonymous">
|
||
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/6.5.1/css/solid.min.css">
|
||
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/font-awesome/6.5.1/css/brands.min.css">
|
||
<link href="https://fonts.googleapis.com/css?family=Montserrat:400,600,700&display=swap" rel="stylesheet">
|
||
<!-- Global site tag (gtag.js) - Google Analytics -->
|
||
<script async src="https://www.googletagmanager.com/gtag/js?id=UA-147034615-1"></script>
|
||
<meta name="msvalidate.01" content="C17405549FB53FD60915A09433C78FF3" />
|
||
<meta http-equiv="X-UA-Compatible" content="IE=EmulateIE8">
|
||
<meta name="viewport" content="width=device-width, initial-scale=1, maximum-scale=1">
|
||
<script>
|
||
window.dataLayer = window.dataLayer || [];
|
||
function gtag(){dataLayer.push(arguments);}
|
||
gtag('js', new Date());
|
||
|
||
gtag('config', 'UA-147034615-1');
|
||
</script>
|
||
|
||
<!-- Google Tag Manager -->
|
||
<script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':
|
||
new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],
|
||
j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src=
|
||
'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);
|
||
})(window,document,'script','dataLayer','GTM-W8TVZ6J');</script>
|
||
<!-- End Google Tag Manager -->
|
||
|
||
<!-- DAP -->
|
||
<script language="javascript" id="_fed_an_ua_tag" src="https://dap.digitalgov.gov/Universal-Federated-Analytics-Min.js?agency=HHS&subagency=NIH&exts=doc,docx,xls,xlsx,xlsm,ppt,pptx,exe,zip,pdf,js,txt,csv,dxf,wmv,jpg,wma,mov,avi,mp3,mp4,csv"></script>
|
||
|
||
<!-- End DAP -->
|
||
</head>
|
||
<body class="fout-fix" data-spy="scroll" data-target="#scrollnav">
|
||
<a href="#main-content" class="visually-hidden focusable">
|
||
Skip to main content
|
||
</a>
|
||
<!-- Google Tag Manager (noscript) -->
|
||
<noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-W8TVZ6J"
|
||
height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>
|
||
<!-- End Google Tag Manager (noscript) -->
|
||
|
||
|
||
<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas>
|
||
<div class="mobile-overlay" id="overlay" aria-hidden="true"></div>
|
||
|
||
<div id="header-container" class="header-container">
|
||
|
||
<div class="ribbon fluid-container">
|
||
<div class="container">
|
||
<div class="row">
|
||
<div class="col-sm-12">
|
||
|
||
<div class="ribbon-links">
|
||
<a href="http://www.hhs.gov/" class="">
|
||
<img src="/assets/hhs-logo.png" alt="U.S. Department of Health & Human Services website"/>
|
||
U.S. Department of Health & Human Services
|
||
</a>
|
||
<img src="/assets/delimiter-arrow.png" alt="" role="presentation"/>
|
||
<a href="https://www.nih.gov/">National Institutes of Health</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="layout-container">
|
||
<header class="container navbar navbar-light navbar">
|
||
<div class="navbar-header-btns">
|
||
<button class="menu-btn" type="button" class="" aria-expanded="false">Menu</button>
|
||
<button class='searchBtnMobile' aria-label="search-toggle"></button>
|
||
|
||
</div>
|
||
<a href="/" class="navbar-logo gtm-header-home" title="Navbar Logo Title"><img src="../../../assets/NIH_HEAL_Color.svg" alt="Navbar Logo Alt"></a>
|
||
<form class="search-menu form-inline d-lg-block" action="https://search.usa.gov/search" accept-charset="UTF-8" method="get">
|
||
<input name="utf8" type="hidden" value="✓">
|
||
<input type="hidden" name="affiliate" id="affiliate" value="heal">
|
||
<div class="input-group">
|
||
<input class="search-input form-control" type="search" placeholder="Search" aria-label="Search heal.nih.gov" name="query">
|
||
<div class="input-group-append">
|
||
<button type="submit" class="btn btn gtm-header-search btn-tertiary">Search</button>
|
||
</div>
|
||
</div>
|
||
</form>
|
||
|
||
|
||
|
||
|
||
<nav role="navigation" aria-labelledby="block-particle-mainnavigation-menu" class="container navbar navbar-expand-lg navbar-light primary-navigation">
|
||
|
||
|
||
|
||
<h2 class="visually-hidden" id="block-particle-mainnavigation-menu">Main navigation</h2>
|
||
|
||
|
||
|
||
|
||
<ul class="no-bullets menu-level-0">
|
||
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-0">
|
||
<a href="/about" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/43151">About</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="no-bullets menu-level-1">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/why-heal" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/43131">Why HEAL?</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/opioid-crisis" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/43136">The Opioid Crisis</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/impact" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/42501">Making a Difference</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/nih-heal-initiative-leadership" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/43146">NIH HEAL Initiative Leadership</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/nih-heal-initiative-annual-report-budget" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/43141">Annual Report and Budget</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/about/strategic-plan" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/46921">Strategic Planning</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-0">
|
||
<a href="/research" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/16">Research</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-1 no-bullets">
|
||
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/research-to-practice" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/61">Translation of Research to Practice for the Treatment of Opioid Addiction</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="no-bullets menu-level-2">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/brim" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/106">Behavioral Research to Improve Medication-Based Treatment</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/continuum-care-hospitalized-patients-opioid-use-disorder" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42151">The Continuum of Care in Hospitalized Patients with Opioid Use Disorder and Infectious Complications of Drug Use</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/enhancing-clinical-trials-network" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/96">Enhancing the National Drug Abuse Treatment Clinical Trials Network to Address Opioids</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/harm-reduction-approaches-reduce-overdose-deaths" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/41416">Harm Reduction Research Network</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/healing-communities" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/91">HEALing Communities Study</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/delivery-healthcare-services-polysubstance-use" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42146">Improving Delivery of Healthcare Services for Polysubstance Use</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/jcoin" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/101">Justice Community Opioid Innovation Network</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/native-collective-research-effort-enhance-wellness-overdose-substance-mental-health-pain" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42586">Native Collective Research Effort to Enhance Wellness (N CREW) Program: Addressing Overdose, Substance Use, Mental Health, and Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/optimizing-addiction-services" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44086">Optimizing the Quality, Reach, and Impact of Addiction Services</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/research-to-practice/research-recovery-network" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/39646">Recovery Research Networks</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/new-strategies" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/66">New Strategies to Prevent and Treat Opioid Addiction</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/care-polysubstance-use-primary-care" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42126">Collaborative Care for Polysubstance use in Primary Care Settings (Co-Care)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/optimizing-care" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/111">Optimizing Care for People with Opioid Use Disorder and Mental Health Conditions</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/duration-retention-discontinuation" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/126">Optimizing the Duration, Retention, and Discontinuation of Medication Treatment for Opioid Use Disorder</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/preventing-opioid-use-disorder" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/116">Preventing Opioid Use Disorder</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/prevent-progression" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/131">Prevention of Progression to Moderate or Severe Opioid Use Disorder</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/new-strategies/sleep-dysfunction" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/121">Sleep Dysfunction as a Core Feature of Opioid Use Disorder and Recovery</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/infants-and-children" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/71">Enhanced Outcomes for Infants and Children Exposed to Opioids</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/infants-and-children/act-now" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/136">Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/infants-and-children/opioid-exposure-during-pregnancy" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44096">The Biology of Opioid Exposure During Pregnancy and Effects on Early Neuro-Behavioral Development</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/infants-and-children/healthy-brain" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/141">HEALthy Brain and Child Development Study (HBCD)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/infants-and-children/virtual-assessments-developmental-trajectories" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44101">Virtual Assessments to Understand Developmental Trajectories of Substance Use Exposure</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/therapeutic-options" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/76">Novel Therapeutic Options for Opioid Use Disorder and Overdose</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/therapeutic-options/immunotherapies" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/151">Development of Novel Immunotherapeutics for Opioid Addiction</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/therapeutic-options/focusing-development" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/146">Focusing Medication Development to Prevent and Treat Opioid Use Disorders and Overdose</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/therapeutic-options/oral-complications-buprenorphine" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44106">Oral Complications Arising From Pharmacotherapies to Treat Opioid Use Disorders</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/therapeutic-options/rapid-assessment-emerging-opioid-threats" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44111">Rapidly Assessing the Public Health Impact of Emerging Opioid Threats</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/clinical-research" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/81">Clinical Research in Pain Management</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/health-equity-pain-management" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42106">Advancing Health Equity in Pain Management</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/pain-signatures" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/186">Acute to Chronic Pain Signatures Program</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/back-pain" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/161">Back Pain Consortium Research Program</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/biomarkers" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/191">Discovery and Validation of Biomarkers, Endpoints and Signatures for Pain Conditions</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/eppic-net" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/176">Early Phase Pain Investigation Clinical Network (EPPIC-Net)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/hemodialysis" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/181">Integrated Approach to Pain and Opioid Use in Hemodialysis Patients</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/pain-management-research" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/166">Pain Management Effectiveness Research Network</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/prism" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/171">Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/chronic-pain-rural-populations" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44091">Prevention and Management of Chronic Pain in Rural Populations</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/clinical-research/integrative-management-chronic-pain" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/39621">Reducing Opioid-Related Harms to Treat Chronic Pain (IMPOWR and MIRHIQL)</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/preclinical-translational" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/86">Preclinical and Translational Research in Pain Management</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/optimization-non-addictive-therapies" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/206">Development and Optimization of Non-Addictive Therapies to Treat Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/novel-targets" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/216">Discovery and Validation of Novel Targets for Safe and Effective Treatment of Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/integrated-research" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/44116">Integrated Basic and Clinical Team-Based Research in Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/screening-platform" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/211">Preclinical Screening Platform for Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/restoring-joint-health-function-reduce-pain" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42136">Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN)</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/discoveries-into-devices" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/201">Translating Discoveries into Effective Devices to Treat Pain</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/preclinical-translational/novel-drugs-screening-platforms" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/196">Translational Research to Advance Testing of Novel Drugs and Human Cell-Based Screening Platforms to Treat Pain and Opioid Use Disorder</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-1">
|
||
<a href="/research/cross-cutting-research" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/40331">Cross-Cutting Research</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-2 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/cross-cutting-research/real-time-opioid-pain-management-data" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42116">Leveraging Existing and Real-Time Opioid and Pain Management Data </a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/cross-cutting-research/small-business-programs" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42111">Small Business Programs </a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/cross-cutting-research/stigma-pain-management-opioid-disorder" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/40256">Stigma in Pain Management and Opioid Use Disorder</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-2">
|
||
<a href="/research/cross-cutting-research/translating-data-action-prevent-overdose" class="menu-link gtm-topnav-third" tabindex="0" data-drupal-link-system-path="node/42121">HEAL Data2Action (HD2A)</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/research/training-next-generation-researchers" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/46831">Training the Next Generation of Researchers in HEAL</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-0">
|
||
<a href="/data" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/44206">Data</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="no-bullets menu-level-1">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/heal-data-ecosystem" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/38836">About the HEAL Data Ecosystem</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/complying-heal-data-sharing-policy" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/39216">Complying With the HEAL Data Sharing Policy</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/common-data-elements" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/39116">Common Data Elements (CDEs) Program</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/common-data-elements-repository" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/42871">Common Data Elements (CDEs) Repository</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/ecosystem-events-outreach" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/40321">HEAL Data Ecosystem Events and Outreach</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/public-access-data" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/51">HEAL Public Access and Data Sharing</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/data/data-ecosystem-collective-board" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/40951">HEAL Data Ecosystem Collective Board</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded menu-item--active-trail no-bullets nav-list-item-0">
|
||
<a href="/funding" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/221">Funding</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-1 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/funding/awarded" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/881">Funded Projects</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/funding/open" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/871">Open Funding Opportunities</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/funding/closed" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/876">Closed Funding Opportunities</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--active-trail no-bullets nav-list-item-1">
|
||
<a href="/funding/research-concepts" class="menu-link gtm-topnav-drop is-active" tabindex="0" data-drupal-link-system-path="node/40206" aria-current="page">Research Concepts</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-0">
|
||
<a href="/news" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/226">News & Events</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-1 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/news/news" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/33666">News</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/news/events" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/33671">Events</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/news/events/headliners" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/42551">Headliners Webinar Series</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/news/stories" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/33676">Research Spotlights</a>
|
||
|
||
</li>
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/videos" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/36351">Videos</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
|
||
<li class="menu-item menu-item--expanded no-bullets nav-list-item-0">
|
||
<a href="/resources" class="menu-link gtm-topnav-link" tabindex="0" data-drupal-link-system-path="node/231">Resources</a>
|
||
|
||
<button class="expand-btn" aria-label="expand-button"></button>
|
||
|
||
|
||
<ul class="menu-level-1 no-bullets">
|
||
|
||
|
||
<li class="menu-item no-bullets nav-list-item-1">
|
||
<a href="/resources/engagement" class="menu-link gtm-topnav-drop" tabindex="0" data-drupal-link-system-path="node/43166">Patient and Community Engagement</a>
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
</li>
|
||
</ul>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</nav>
|
||
|
||
|
||
</header>
|
||
|
||
<div data-drupal-messages-fallback class="hidden"></div>
|
||
|
||
|
||
|
||
|
||
<div class="color-gradient"></div>
|
||
|
||
<main role="main">
|
||
<div class="container">
|
||
<a id="main-content" tabindex="-1"></a>
|
||
<div class="row">
|
||
<div class="col-sm-12 breadcrumb-col col-md-7">
|
||
<div id="block-particle-breadcrumbs">
|
||
|
||
|
||
|
||
|
||
<nav aria-label="breadcrumb" role="navigation">
|
||
<ol class="breadcrumb">
|
||
<li class="breadcrumb-item gtm-breadcrumb"><a href="/" class="gtm-breadcrumb">Home</a></li>
|
||
<li class="breadcrumb-item gtm-breadcrumb"><a href="/funding" class="gtm-breadcrumb">Funding</a></li>
|
||
<li class="breadcrumb-item active is-active gtm-breadcrumb" aria-current="page">Research Concepts</li>
|
||
</ol>
|
||
</nav>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
<div class="col-sm-12 col-md-5">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="layout-content">
|
||
<div>
|
||
<div id="block-particle-content">
|
||
|
||
|
||
|
||
|
||
<h1> Research Concepts </h1>
|
||
|
||
|
||
<div>
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<p>A Research Concept describes the basic purpose, scope, and objectives of a potential solicitation of grants or contracts. Current concepts under development are listed below to alert researchers to areas of NIH HEAL Initiative research interest and to give researchers maximal lead time to plan projects. Past concepts that have converted to funding opportunities (NOFOs) can be found at the bottom of the page. Please note that not every concept will lead to a NOFO. The NIH HEAL Initiative bases this determination on scientific and programmatic priorities and the availability of funds, and a NOFO may also differ in certain details from its originating concept. Please visit this page often for updates, <a href="https://public.govdelivery.com/accounts/USNIHNIDA/signup/43013" target="_blank">subscribe to the HEAL Digest</a> for updates, and view <a href="https://heal.nih.gov/funding/open">current</a> (open) and <a href="https://heal.nih.gov/funding/closed">past</a> (closed) HEAL NOFOs.</p><p><strong>Research Concepts on this page</strong>:</p><ul><li><a href="/funding/research-concepts#translation-of-research-to-practice-for-the-treatment-of-opioid-addiction">Translation of Research to Practice for the Treatment of Opioid Addiction</a></li><li><a href="/funding/research-concepts#new-strategies-to-prevent-and-treat-opioid-addiction">New Strategies to Prevent and Treat Opioid Addiction</a></li><li><a href="/funding/research-concepts#enhanced-outcomes-for-infants-and-children-exposed-to-opioids">Enhanced Outcomes for Infants and Children Exposed to Opioids</a></li><li><a href="/funding/research-concepts#novel-medication-options-for-opioid-use-disorder-and-overdose">Novel Therapeutic Options for Opioid Use Disorder and Overdose</a></li><li><a href="/funding/research-concepts#clinical-research-in-pain-management">Clinical Research in Pain Management</a></li><li><a href="/funding/research-concepts#preclinical-and-translational-research-in-pain-management">Preclinical and Translational Research in Pain Management</a></li><li><a href="/funding/research-concepts#past">Past Concepts</a></li></ul>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id="translation-of-research-to-practice-for-the-treatment-of-opioid-addiction"><h2 id="h3--translation-of-research-to-practice-for-the-treatment-of-opioid-addiction-">Translation of Research to Practice for the Treatment of Opioid Addiction</h2></div><h3>American Indian and Alaska Native Collective Research Effort to Enhance Wellness: Addressing Opioid/Drug Misuse and Overdose, Mental Health, and Pain</h3><p>This concept will support Tribes and American Indian/Alaska Native (AI/AN) serving organizations and communities to respond to the opioid/drug overdose crisis by establishing or expanding research infrastructure and capacity for Tribal research entities to conduct research related to all facets of the opioid/overdose crisis, including substance misuse, mental health related factors, and the management of pain. It will address data insufficiencies by providing support to improve data and surveillance of factors that contribute to the opioid/drug overdose crisis at the local level (including local data and connections to state, regional and national data). Increasing research capacity will include supporting the conduct of Tribally or community prioritized research. The concept will fund technical assistance and provide support for the development of any needed partnerships to achieve all program goals. A Tribal Consultation informed the development of this concept. <a href="https://dpcpsi.nih.gov/thro/tribal-consultations/nih-heal-initiative">HEAL Tribal Consultation Report</a></p><p>Contact: <a href="/cdn-cgi/l/email-protection#84efe1f0fec4eaede0e5aaeaedecaae3ebf2">Kathy Etz</a></p><h3 id="workforce">Workforce Interventions to Improve Addiction Care Quality and Patient Outcome</h3><p>This concept aims to design and test workforce interventions that could lead to improved care quality and patient outcomes. It will support research to better understand dynamics that influence workforce recruitment, training, performance, and retention – an important aim since the demand for addiction counselors could dramatically exceed supply by approximately 38% in 2030, a shortage of nearly 35,000 workers.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#1165786279703f66787d7468517f78793f767e67">Tisha Wiley</a>, <a href="/cdn-cgi/l/email-protection#0473616a607d2a7361666176446a6d6c2a636b72">Wendy Weber</a></p><h3 id="career"><strong>Career Development Awards in Addiction Implementation Science</strong></h3><p>This concept will provide an opportunity for early career scientists or early career clinicians with foundational backgrounds in addiction to develop expertise in implementation science, including conducting a research project incorporating at least one of the four priority domains of the <a href="https://www.hhs.gov/overdose-prevention/">HHS Overdose Prevention Strategy</a>: primary prevention (including appropriate opioid prescribing), opioid use disorder treatment, harm reduction, and recovery support services. This research aims to build a cadre of implementation researchers who can contribute to addressing the current overdose crisis, develop research careers that will impact the quality of clinical practice generally, and become the next generation of implementation experts and mentors.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#cbbfa2b8a3aae5bca2a7aeb28ba5a2a3e5aca4bd">Tisha Wiley</a>, <a href="/cdn-cgi/l/email-protection#16617378726f38617374736456787f7e38717960">Wendy Weber</a></p><h3 id="foster">Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On</h3><p>This concept will leverage existing quality measurement efforts to advance the field of addiction science to help patients, families, and payers identify effective providers and promote improvements in patient outcomes. This research will support research centers consisting of partnerships between researchers and payors, health plans, single state agencies/opioid treatment authorities, professional organizations, or other entities who can deploy a quality measurement and management system to inform provider or clinician selection and treatment improvement.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#5e2a372d363f702937323b271e30373670393128">Tisha Wiley</a>, <a href="/cdn-cgi/l/email-protection#b7c0d2d9d3ce99c0d2d5d2c5f7d9dedf99d0d8c1">Wendy Weber</a></p><h3 id="exposure">Addressing Exposure to Violence and Trauma in the Context of Substance Use Disorder Treatment and Recovery Services</h3><p>This concept aims to address exposure to violence and related trauma among individuals with substance use disorders, for whom integrated services are lacking. This research will adapt the <a href="https://heal.nih.gov/research/new-strategies/optimizing-care">Optimizing Care for People with Opioid Use Disorder and Mental Health Conditions</a> research approach that tests the adaptation, effectiveness, adoption, scalability, and sustainability of collaborative care to include exposure to violence and trauma – as well as extend the focus of research beyond primary care settings to include recovery and substance use disorder treatment settings.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#73071a001b125d041a1f160a331d1a1b5d141c05">Tisha Wiley</a>, <a href="/cdn-cgi/l/email-protection#493e2c272d30673e2c2b2c3b09272021672e263f">Wendy Weber</a></p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id="new-strategies-to-prevent-and-treat-opioid-addiction"><h2 id="h3--new-strategies-to-prevent-and-treat-opioid-addiction-">New Strategies to Prevent and Treat Opioid Addiction</h2></div><h3>Sleep and Circadian Predictors of Opioid Use Disorder Treatment Response and Outcomes</h3><p>This concept proposes a data science approach to evaluate and integrate sleep- and circadian-based behavioral, physiological, and molecular phenotypes predictive of opioid use disorder treatment outcomes. The goal is to produce a predictive model of opioid use disorder outcomes based on sleep and circadian indicators that helps to identify potential intervention targets to prevent relapse and enhance the effectiveness of opioid use disorder treatment.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#5a3d3f3f2e323b74292f38283b373b34333b371a343332743d352c">Geetha Subramaniam</a>, <a href="/cdn-cgi/l/email-protection#2d4c4148554c4349485f03594c4146425b5e46546d434445034a425b">Alex Talkovsky</a></p><h3 id="evidence">Evidence Based Prevention Interventions in Community Health Centers</h3><p>This concept aims to develop and test strategies for providing improved access to preventative intervention services for patients served by community health centers (CHCs). These locations are well positioned to serve as a formal point of entry into evidence-based opioid misuse prevention services because they reach large numbers of people affected by the opioid crisis and are situated across the nation in low-resourced areas. The research will focus on primary prevention strategies for opioid misuse as well as enhance risk screening processes in CHCs.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#86e1e3e3f2eee7a8f5f3e4f4e7ebe7e8efe7ebc6e8efeea8e1e9f0">Geetha Subramaniam</a>, <a href="/cdn-cgi/l/email-protection#e2838e879a838c868790cc96838e898d9491899ba28c8b8acc858d94">Alex Talkovsky</a></p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id="enhanced-outcomes-for-infants-and-children-exposed-to-opioids"><h2 id="h3--enhanced-outcomes-for-infants-and-children-exposed-to-opioids-">Enhanced Outcomes for Infants and Children Exposed to Opioids</h2></div><h3>Neonatal and Infant Imaging and Placenta Function<strong> </strong></h3><p>This concept addresses the need to understand how opioid exposure, alone or in combination with other substances (e.g., alcohol, tobacco, and marijuana), during pregnancy can influence placental function and brain development. Brain development during the fetal, neonatal, and infancy periods is highly plastic and susceptible to environmental influences, including maternal substance use, nutrition, and environmental adversity. Despite longstanding knowledge that the placenta is a critical organ in fetal development, there is limited knowledge about how opioid use by pregnant women affects placental function to influence and alter fetal brain development.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#44223621312a20290429252d286a2a2d2c6a232b32">Michelle Freund</a>, <a href="/cdn-cgi/l/email-protection#0968676d7b6c7e276b7b6c646c7b49676061276e667f">Drew Bremer</a></p><h3>Remote Assessments</h3><p>This concept will build upon the pandemic-invoked deployment and acceptance of remote technology interactions, with the goal of transitioning data collection thoughtfully and systematically out of traditional lab-based settings into homes. This research aims to enhance inclusion of study populations by expanding its representativeness and lowering the burden of families to participate in clinical neuroscience research studies. It will establish validated ways to virtually measure sociocultural, biobehavioral, and environmental factors, such as substance use exposures.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#a6c0d4c3d3c8c2cbe6cbc7cfca88c8cfce88c1c9d0">Michelle Freund</a>, <a href="/cdn-cgi/l/email-protection#adccc3c9dfc8da83cfdfc8c0c8dfedc3c4c583cac2db">Drew Bremer</a></p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id=" Novel Therapeutic Options for Opioid Use Disorder and Overdose"><h2 id="h3--novel-therapeutic-options-for-opioid-use-disorder-and-overdose-">Novel Therapeutic Options for Opioid Use Disorder and Overdose</h2></div><h3 id="therapeutics">Therapeutics Development for Comorbid Opioid Use Disorder and Stress-Related Mental Disorders</h3><p>This concept will broaden the scope of addiction treatment development, integrating stress-related psychiatric comorbidities and substance use disorders together into therapeutics development. Stress is common in people who develop substance use disorders and stress-related mental disorders, such as depression and anxiety, including post-traumatic stress disorder. These stress-related comorbidities are not currently integrated into the therapeutics clinical development path. This research will assess standalone treatment options as well as combinations of a pharmacotherapy and neuromodulation, toward meeting the needs of complex patient populations.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#e9808486879d869088a984888085c7878081c78e869f">Ivan Montoya</a>, <a href="/cdn-cgi/l/email-protection#a5cec0cbd1cbc0d78bd6cccbc2c9c0d1cacbe5cbcccd8bc2cad3">Kentner Singleton</a></p><h3>Oral Complications Arising from Oral Buprenorphine Use</h3><p>This concept will support basic science research to understand the oral cavity biochemical environment during oral buprenorphine use. This research also aims to elucidate the role of microbial flora and salivary proteins in the development and progression of reported oral complications to buprenorphine. There is limited scientific literature to describe oral complications of buprenorphine use, and different etiologies may contribute to these reported problems.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#e28b8f8d8c968d9b83a28f838b8ecc8c8b8acc858d94">Ivan Montoya</a>, <a href="/cdn-cgi/l/email-protection#90fbf5fee4fef5e2bee3f9fef7fcf5e4fffed0fef9f8bef7ffe6">Kentner Singleton</a></p><h3>Addressing the Public Health Impact of New and Emerging Opioid Threats <strong> </strong></h3><p>This concept aims to address the urgent need to understand emerging opioid threats, including toxicology of these new substances. The research aims to enlist the help of toxicologists, medical examiners, and biomedical assay developers, in addition to pharmacologists, emergency department physicians, and addiction specialists. This research aims to provide rapidly delivered, actionable information for public health professionals and policy makers about the dangers of new threats and their impact on opioid addiction and overdose treatments, as well as on resulting illness and death.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#c4b4abb6b0a1b6a884aaadaaa0b7eaaaadaceaa3abb2">Linda Porter</a>, <a href="/cdn-cgi/l/email-protection#9af0fbeef1f3f4e9f5daf7fbf3f6b4f4f3f2b4fdf5ec">Jane Atkinson</a></p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id="clinical-research-in-pain-management"><h2 id="h3--clinical-research-in-pain-management-">Clinical Research in Pain Management</h2></div><h3>Coordinated Pain Care in Health Care Systems</h3><p>This proposed concept will support research projects to embed effective coordinated pain care into health care systems. The goal is to improve pain relief and health outcomes through coordinated interventions such as medication or injections provided by a single health care provider. The coordinated care strategy could be centered in primary care settings with an integrated referral system to specialty care or could be centered in specialty care programs and coordinated with primary care.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#b7c7d8c5c3d2c5dbf7d9ded9d3c499d9dedf99d0d8c1">Linda Porter</a>, <a href="/cdn-cgi/l/email-protection#5933382d3230372a36193438303577373031773e362f">Jane Atkinson</a></p><h3 id="chronic">Chronic Pain Management in Rural Populations</h3><p>This concept aims to accelerate the use of evidence-based non-opioid chronic pain interventions in rural and remote communities with health disparities. Compared to people in non-rural areas, rural residents are more likely to be prescribed an opioid pain medication and less likely to use pain self-management approaches. The program will leverage the existing <a href="/research/clinical-research/prism">Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM)</a> Resource Coordinating Center to provide expertise and technical support.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#c9b9a6bbbdacbba589a7a0a7adbae7a7a0a1e7aea6bf">Linda Porter</a>, <a href="/cdn-cgi/l/email-protection#ec868d988785829f83ac818d8580c2828584c28b839a">Jane Atkinson</a> </p><h3 id="multilevel">Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy</h3><p>This concept addresses the needs of individuals on long-term opioid therapy who underwent aggressive tapering beyond federal guideline recommendations. Such patients have become opioid dependent (but don’t meet criteria for opioid use disorder) and do not have sufficient pain relief. With unclear treatment plans, these patients have fallen through the cracks of the American health care system. This research will develop multi-level interventions targeting patients, providers/pharmacists, and health systems. It aims to strengthen the evidence for best for tapering practices that are tailored, flexible, and patient centered.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#88f8e7fafcedfae4c8e6e1e6ecfba6e6e1e0a6efe7fe">Linda Porter</a>, <a href="/cdn-cgi/l/email-protection#a1cbc0d5cac8cfd2cee1ccc0c8cd8fcfc8c98fc6ced7">Jane Atkinson</a></p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--basic-content paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class='basic-content content-align-left padding-bottom--1'>
|
||
<div class='basic-content-grid-container ' style=''>
|
||
<div class="basic-content-grid-no-media">
|
||
<div>
|
||
|
||
<div class="card-header" id="preclinical-and-translational-research-in-pain-management"><h2 id="h3--preclinical-and-translational-research-in-pain-management-">Preclinical and Translational Research in Pain Management</h2></div><h3>Clinical Translation of Diagnostic and Therapeutic Devices via Blueprint MedTech <strong> </strong></h3><p>This concept will facilitate clinical translation of diagnostic and therapeutic devices to treat pain and opioid use disorder. It will operate through the existing <a href="https://neuroscienceblueprint.nih.gov/neurotherapeutics/blueprint-medtech/blueprint-medtech">Blueprint MedTech</a> program, an NIH incubator that catalyzes the translation of novel neurotechnologies from early-stage development to first-in-human clinical studies. The program will support grantees by providing commercialization, verification, and validation resources. The goal is to develop and de-risk technologies to the point where additional investments are warranted from industry partners, investors, and government.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#e4898d878c858188ca8b978c8d8a978f9da48a8d8cca838b92">Michael Oshinsky</a>, <a href="/cdn-cgi/l/email-protection#0e6d667c677d7a67606b206d616278677d4e60676620696178">Christine Colvis</a></p><h3 id="integrated-research">Integrated Basic and Clinical Research in Pain</h3><p>This concept will support both clinical and preclinical pain research within one research study and grant. The goal is to understand the biology of specific human pain conditions as well as pain associated with diverse diseases/disorders, including devising ways to differentiate and stratify patients with specific pain conditions and co-morbidities. This concept will also enhance the pain workforce through investigators’ exposure to multidisciplinary pain research including clinical pain management and research, preclinical/basic pain biology and modeling, human psychology, specific disease and/or pathological conditions, animal behavior, and data science.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#abc6c2c8c3cacec785c4d8c3c2c5d8c0d2ebc5c2c385ccc4dd">Michael Oshinsky</a>, <a href="/cdn-cgi/l/email-protection#e6858e948f95928f8883c885898a908f95a6888f8ec8818990">Christine Colvis</a></p><h3 id="animal-models">Development and Validation of Animal Models and Outcome Measures for Pain</h3><p>This concept will facilitate rigorous validation of animal models and/or endpoints for both pain biology studies and therapeutics development at all stages. Studies on small, medium, and large animal pain models and associated outcome measures will identify species differences in pain biology that could meaningfully inform human pain mechanisms and pain conditions. Through independent replication studies, this research will strengthen confidence in the use of animal models for pain research.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#9ef3f7fdf6fffbf2b0f1edf6f7f0edf5e7def0f7f6b0f9f1e8"><span class="__cf_email__" data-cfemail="107875717c6165756364797f7e507f743e7e79783e777f66">[email protected]</span></a></p><h2 id="past"><strong>Past Concepts</strong></h2><p>These past concepts have converted to funding opportunities (see links).</p>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--accordion paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class="pattern">
|
||
|
||
|
||
|
||
<div id="accordion-875014969" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-875014969-0">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-875014969-0"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-875014969-0">
|
||
Translation of Research to Practice for the Treatment of Opioid Addiction
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-875014969-0"
|
||
class="collapse "
|
||
aria-labelledby="heading-875014969-0"
|
||
data-parent="#accordion-875014969">
|
||
<div class="card-body">
|
||
<h3>Actionable Data to Inform Research‐Driven Decisions (Data2Action)</h3><p>This concept aims to attract researchers who have data in hand and new or existing tools or methods to conduct predictive analyses to 1) use data sources that are accessible and analyzed on a timescale allowing for predictive and proactive responses, and 2) leverage partnerships with key stakeholders to turn research results directly toward decisions and implementation. The goal is to obtain actionable data to provide a precise picture of trends in opioid use and overdose in communities, toward facilitating responses at national, state, and local levels.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#bbcfd2c8d3da95ccd2d7dec2fbd5d2d395dcd4cd">Tisha Wiley</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-049.html">HEAL Data2Action Modeling and Economic Resource Center (U24 Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-050.html">HEAL Data2Action Research Adoption Support Center (U2C Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-051.html">HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-052.html">HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)</a></li></ul><h3>Research Adoption Partnerships</h3><p>This concept aims to build partnerships among researchers and public/private sector stakeholders to help overcome barriers to adopting evidence‐based practices for preventing and treating opioid use disorder. It will establish a national resource center to promote equitable dissemination and implementation of evidence‐based practices addressing the opioid crisis. The concept will leverage partnerships with stakeholders, existing infrastructure, and implementation experts, as well as conduct original trials of implementation strategies within multiple systems of care.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#7105180219105f06181d1408311f18195f161e07">Tisha Wiley</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-049.html">HEAL Data2Action Modeling and Economic Resource Center (U24 Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-050.html">HEAL Data2Action Research Adoption Support Center (U2C Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-051.html">HEAL Data2Action Innovation Projects (R61/R33 Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-052.html">HEAL Data2Action (HD2A) Data Infrastructure Support Center (U24 Clinical Trial Optional)</a></li></ul><h3>Understanding Polysubstance Use and Improving Addiction Service Delivery</h3><p>This concept proposes to support research related to polysubstance use in which individuals use multiple substances and have one or more substance use disorders. The research aims to expand understanding about the dynamics of polysubstance use, examine impacts of existing policies and services on services and treatment outcomes, study personalized treatment and services approaches to address polysubstance use, and develop effective strategies for using existing treatments most effectively to address the needs of polysubstance use patients. This research is timely given trends suggesting that responses to the evolving opioid crisis should more holistically consider the variety of substances people use simultaneously.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#86f2eff5eee7a8f1efeae3ffc6e8efeea8e1e9f0">Tisha Wiley</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/rfa-da-22-047.html">Understanding Polysubstance Use and Improving Service Delivery to Address Polysubstance Use</a></li></ul><h3 id="testing">Recovery Support Services for People Treated with Medications for Opioid Use Disorder </h3><p>This concept aims to build resources for research on recovery support. Areas of interest include infrastructure support to advance the development of efficacy and/or effectiveness research, as well as pilot and preliminary research in preparation for rigorous clinical efficacy or effectiveness trials of recovery support services or combinations of those services for individuals who take medications for the treatment of opioid use disorder. Relevant approaches may address infrastructure gaps or test a wide range of recovery support services (or combinations of those services) where rigorous evidence of efficacy and effectiveness is lacking.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#91e5f8e2f9f0bfe6f8fdf4e8d1fff8f9bff6fee7">Tisha Wiley</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-034.html">Planning Grants for Efficacy or Effectiveness Trials of Recovery Support Services for Individuals Treated with Medications for Opioid Use Disorder (R34 Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-043.html">Research Networks for the Study of Recovery Support Services for Persons Treated with Medications for Opioid Use Disorder (R24 Clinical Trial Optional)</a></li></ul><h3>Harm Reduction Policies, Practices, and Modes of Delivery for People with Substance Use Disorders</h3><p>This concept proposes to support research related to harm reduction. Areas of interest include developing, testing, and implementing new and existing strategies; expanding settings for their use and delivery; and examining the impact of new harm reduction policies implemented at state and local levels. Examples of established harm reduction approaches include naloxone, fentanyl test strips, safer smoking equipment, and sterile syringes, as well as HIV and hepatitis C virus testing.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#394d504a5158174e50555c4079575051175e564f">Tisha Wiley</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/rfa-da-22-046.html">Harm Reduction Policies, Practices, and Modes of Delivery for Persons with Substance Use Disorders</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-042.html">HEAL Initiative: Harm Reduction Policies, Practices, and Modes of Delivery for Persons with Substance Use Disorders: Coordination Center</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-1867945623" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1867945623-1">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1867945623-1"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-1867945623-1">
|
||
New Strategies to Prevent and Treat Opioid Addiction
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-1867945623-1"
|
||
class="collapse "
|
||
aria-labelledby="heading-1867945623-1"
|
||
data-parent="#accordion-1867945623">
|
||
<div class="card-body">
|
||
<h3>Social Determinants of Opioid Use: Opportunities for Community- and System-Level Interventions</h3><p>This concept will leverage existing research programs that target identified social determinants (e.g., housing, employment) and study the effects of adding psychosocial and/or behavioral interventions, with the goal of more directly addressing mechanisms related to opioid misuse and related outcomes. Projects are expected to specify and study mechanistic pathways through which interventions confer their effects. The primary goal of these studies would be to test the impact of multi-level strategies that directly address social determinants of health on risk for opioid use and related outcomes.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#0d6c6e7f78607d4d6364696c23636465236a627b">Aria Davis Crump</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-036.html">Preventing Opioid Misuse and Co-Occurring Conditions by Intervening on Social Determinants (R01 Clinical Trials Optional)</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-409030391" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-409030391-2">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-409030391-2"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-409030391-2">
|
||
Enhanced Outcomes for Infants and Children Exposed to Opioids
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-409030391-2"
|
||
class="collapse "
|
||
aria-labelledby="heading-409030391-2"
|
||
data-parent="#accordion-409030391">
|
||
<div class="card-body">
|
||
<h3>Neonatal and Infant Imaging and Placenta Function <strong> </strong></h3><p>This concept addresses the need to understand how opioid exposure, alone or in combination with other substances (e.g., alcohol, tobacco, and marijuana), during pregnancy can influence placental function and brain development. Brain development during the fetal, neonatal, and infancy periods is highly plastic and susceptible to environmental influences, including maternal substance use, nutrition, and environmental adversity. Despite longstanding knowledge that the placenta is a critical organ in fetal development, there is limited knowledge about how opioid use by pregnant women affects placental function to influence and alter fetal brain development.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#365044534358525b765b575f5a18585f5e18515940">Michelle Freund</a>, <a href="/cdn-cgi/l/email-protection#3e5f505a4c5b49105c4c5b535b4c7e50575610595148">Drew Bremer</a></p><h3>Remote Assessments</h3><p>This concept will build upon the pandemic-invoked deployment and acceptance of remote technology interactions, with the goal of transitioning data collection thoughtfully and systematically out of traditional lab-based settings into homes. This research aims to enhance inclusion of study populations by expanding its representativeness and lowering the burden of families to participate in clinical neuroscience research studies. It will establish validated ways to virtually measure sociocultural, biobehavioral and environmental factors, such as substance use exposures.</p><p>Contacts: <a href="/cdn-cgi/l/email-protection#b6d0c4d3c3d8d2dbf6dbd7dfda98d8dfde98d1d9c0">Michelle Freund</a>, <a href="/cdn-cgi/l/email-protection#fa9b949e889f8dd498889f979f88ba949392d49d958c">Drew Bremer</a></p>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-143887529" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-143887529-3">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-143887529-3"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-143887529-3">
|
||
Novel Therapeutic Options for Opioid Use Disorder and Overdose
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-143887529-3"
|
||
class="collapse "
|
||
aria-labelledby="heading-143887529-3"
|
||
data-parent="#accordion-143887529">
|
||
<div class="card-body">
|
||
<h3>Medications Development for Opioid Use Disorder and Opioid Overdose </h3><p>This concept is to support research to advance development for FDA approval of safe and effective medications to treat and prevent overdose among individuals with concomitant use of opioids with stimulants (methamphetamine and cocaine) and other substances. Treatment for polysubstance use disorder is a public health priority, given the current alarming trends in morbidity and mortality from opioids and other substances, exacerbated by the COVID-19 pandemic. Nearly 40% of opioid-involved overdose deaths also involved stimulants, including methamphetamine or cocaine.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#a7cecac8c9d3c8dec6e7cac6cecb89c9cecf89c0c8d1">Ivan Montoya</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/pa-files/par-20-092.html">Development of Medications to Prevent and Treat Opioid Use Disorders and Overdose (UG3/UH3) (Clinical Trial Optional)</a></li><li><a href="https://grants.nih.gov/grants/guide/notice-files/NOT-DA-22-049.html#:~:text=NOT%2DDA%2D22%2D049,Development%20for%20Stimulant%20Use%20Disorders">Notice of Special interest (NOSI): Medications Development for Stimulant Use Disorders</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-1078470574" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1078470574-4">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1078470574-4"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-1078470574-4">
|
||
Clinical Research in Pain Management
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-1078470574-4"
|
||
class="collapse "
|
||
aria-labelledby="heading-1078470574-4"
|
||
data-parent="#accordion-1078470574">
|
||
<div class="card-body">
|
||
<h3>Enhancing the Clinical Pain Management Workforce Initiative</h3><p>This proposed concept will promote the expansion and enhancement of a diverse workforce of highly trained scientists in clinical pain research through a nationwide mentoring and networking program. It will provide mentoring and skills necessary to support practitioners who seek a career in clinical pain management research. Another goal is to create an environment where early-stage clinical pain researchers can connect and collaborate with early and experienced basic and translational researchers through a centralized network and sponsored events.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#92e2fde0e6f7e0fed2fcfbfcf6e1bcfcfbfabcf5fde4">Linda Porter</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-045.html">National K12 Clinical Pain Career Development Program (K12 Clinical Trial Not Allowed)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-046.html">Coordinating Center for National Pain Scientists Career Development (R24 Clinical Trial Not Allowed)</a></li></ul><p><strong>Advancing Health Equity</strong></p><p>These proposed concepts will support research projects to develop, test, and implement novel, culturally appropriate pain interventions and/or adapt, test, and evaluate efficacy and effectiveness of existing pain interventions, in populations that disproportionately experience negative health outcomes. Desired outcomes of these interventions include reduction of pain and pain-related symptoms, and improvement in overall health outcomes, including function and quality of life. Interventions that target populations that experience health disparities with chronic pain in addition to at least one comorbid condition (opioid use disorder, mental health disorders, and/or chronic health conditions) are of the highest priority.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#b4d7dcd1c6cdc7d19ac7d5dadfd5c6f4dadddc9ad3dbc2">Cheryse Sankar</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-002.html">Advancing Health Equity in Pain Management</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-22-037.html">Advancing Health Equity in Pain and Comorbidities</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-1619941810" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1619941810-5">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1619941810-5"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-1619941810-5">
|
||
Preclinical and Translational Research in Pain Management
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-1619941810-5"
|
||
class="collapse "
|
||
aria-labelledby="heading-1619941810-5"
|
||
data-parent="#accordion-1619941810">
|
||
<div class="card-body">
|
||
<h3>Translational Training Awards in Pain and Addiction Research</h3><p>This concept will provide early- and mid-career scientists who have pain or opioid misuse expertise with hands-on training in translation in industry, academia, or government research laboratories. The jointly prepared research experience plan will be centered around the development of a therapeutic to treat pain or addiction, and the trainee will be expected to receive broad exposure to therapy development, while the translational institution will benefit from the trainee’s pain or addiction domain expertise.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#1b787874776d72685b767a727735757273357c746d">Christine Colvis</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/pa-files/PAR-22-058.html">Translational Science Career Enhancement Awards for Early and Mid-career Investigators (K18 Clinical Trials Not Allowed)</a></li></ul><h3>Pain Target Discovery and Validation Initiative</h3><p>This concept will promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. It focuses on the basic science validation of targets in the peripheral nervous system, central nervous system, immune system, or other tissues in the body that can be used to develop analgesics that have minimal side effects and little to no misuse/addiction liability. Research projects must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. The overall goal of this initiative is to lower the risk of adopting a new pain target in future translational projects to develop small molecules, biologics, natural substances, or devices that interact with this target for new pain treatments.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#c4a9ada7aca5a1a8eaabb7acadaab7afbd84aaadaceaa3abb2">Michael Oshinsky</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/rfa-ns-22-034.html">Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)</a></li></ul><h3>HEAL New Innovator Awards</h3><p>This concept will support scientists with high-impact, outside-the-box ideas to find novel treatments for pain, opioid addiction, and overdose. Because effective treatment will require highly innovative ideas, transformative, boundary-pushing applications are often risky or at a stage too early to fare well in the traditional peer review process. The NIH HEAL Initiative-specific New Innovator Award will encourage fresh and original ideas from young investigators proposing research in areas within the HEAL mission.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#afccccc0c3d9c6dcefc2cec6c381c1c6c781c8c0d9">Christine Colvis</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-22-013.html">New Innovator Award (DP2 Clinical Trial Not Allowed)</a></li></ul><h3>Illuminating the Druggable Genome to Uncover New Targets for Treating Pain and Opioid Use Disorder</h3><p>This concept will promote discovery of “dark” proteins in pain, addiction, and overdose by identifying and validating new targets for pain and opioid use disorder among the understudied proteins of the Druggable Genome. While the number of proteins in the Druggable Genome is upwards of 3,000, the existing clinical pharmacopeia has only a few hundred targets, leaving a huge swath of biology that remains unexplored. Many dark proteins have been linked to pain, pain perception, and opioid dependence.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#0f6c6c606379667c4f626e66632161666721686079">Christine Colvis</a></p><p>Funding Opportunity:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-22-011.html">Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed)</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<div id="accordion-1018237050" class="col-12 accordion">
|
||
|
||
|
||
|
||
<div class="card-header col-12" id="heading-1018237050-6">
|
||
|
||
<h2 class="mb-0">
|
||
<button class="btn btn-link h2 expand-link"
|
||
data-toggle="collapse"
|
||
data-target="#collapse-1018237050-6"
|
||
aria-expanded="false"
|
||
aria-controls="collapse-1018237050-6">
|
||
Other
|
||
</button>
|
||
</h2>
|
||
|
||
</div>
|
||
|
||
<div id="collapse-1018237050-6"
|
||
class="collapse "
|
||
aria-labelledby="heading-1018237050-6"
|
||
data-parent="#accordion-1018237050">
|
||
<div class="card-body">
|
||
<p><strong>Real‐World Data to Address Urgent Opioid Use Disorder/Substance Use Disorder Needs</strong></p><p>This concept will encourage development of new methods and approaches to update and aggregate data from existing sources (e.g., electronic health records, claims data, registry data, pharmacy dispensing, and mortality records). Several challenges prevent efficient linking and leveraging of these existing “real world” data in ways that can be used to provide real‐time or near-real-time understanding of a constantly changing drug overdose epidemic. Increasing visibility of such data could provide new insights into the dynamics of substance use, addiction, recovery, and relapse.</p><p>Contact: <a href="/cdn-cgi/l/email-protection#ea9e8399828bc49d83868f93aa848382c48d859c">Tisha Wiley</a></p><p>Funding Opportunities:</p><ul><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-045.html">Exploratory Data and Methods to Address Urgent Needs to Stem the Opioid Epidemic (R21- Clinical Trial Not Allowed)</a></li><li><a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-044.html">Data and Methods to Address Urgent Needs to Stem the Opioid Epidemic (R01- Clinical Trial Not Allowed)</a></li></ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="paragraph paragraph--type--cards paragraph--view-mode--default">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="container">
|
||
<div class="row card-grid pattern">
|
||
|
||
<div class='col-lg-4 col-md-6 col-sm-12'>
|
||
<div class='border-none card'>
|
||
|
||
|
||
<div class='card-body'>
|
||
<h3 class='card-title'>
|
||
Wanted: New Ideas for a New Year
|
||
</h3>
|
||
<div class='card-text'>
|
||
<p>The NIH HEAL Initiative® announces several new funding opportunities and research concepts in harm reduction, polysubstance use, pain health disparities, recovery, and other areas relevant to the HEAL mission.</p>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-primary gtm-card-button bottom-button mt-2" href=/about/director/new-ideas-new-year>
|
||
Read the Director's Message
|
||
</a>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class='col-lg-4 col-md-6 col-sm-12'>
|
||
<div class='border-none card'>
|
||
|
||
|
||
<div class='card-body'>
|
||
<h3 class='card-title'>
|
||
NIH HEAL Initiative® Research
|
||
</h3>
|
||
<div class='card-text'>
|
||
<p>The NIH HEAL Initiative® is organized into six research focus areas. Within those focus areas are 28 research programs to find scientific solutions to the opioid crisis.</p>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-primary gtm-card-button bottom-button mt-2" href=/research>
|
||
Read Research page
|
||
</a>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class='col-lg-4 col-md-6 col-sm-12'>
|
||
<div class='border-none card'>
|
||
|
||
|
||
<div class='card-body'>
|
||
<h3 class='card-title'>
|
||
NIH HEAL Initiative® Notices of Special Interest (NOSI) and Funding Opportunities
|
||
</h3>
|
||
<div class='card-text'>
|
||
<p>Search for new funding opportunities from the NIH HEAL initiative® and learn more about the more than 600 currently funded awards in HEAL’s 28 research programs.</p>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<a class="btn btn-primary gtm-card-button bottom-button mt-2" href=/funding/open>
|
||
View Funding Opportunities
|
||
</a>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
|
||
</main>
|
||
<div class="container">
|
||
<p class="last-updated">Page last updated
|
||
October 23, 2024</p>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<footer class="fluid-container p-3 footer" role="contentinfo">
|
||
<div class="container">
|
||
<div class="row">
|
||
<div class="col-12 col-md-3">
|
||
<div class="footer-logo"><a href="/"><img alt="NIH HEAL Initiative" src="/assets/HEAL_Initaitive_White.svg" /></a></div>
|
||
|
||
<h2>Contact Us</h2>
|
||
|
||
<p>Please send email to <a href="/cdn-cgi/l/email-protection#034b46424f72766670776a6c6d436c672d6d6a6b2d646c75"><span class="__cf_email__" data-cfemail="531b16121f22263620273a3c3d133c377d3d3a3b7d343c25">[email protected]</span></a></p>
|
||
</div>
|
||
|
||
<div class="col-6 col-md-3">
|
||
<h2><a class="gtm-footer-link" href="/about">About</a></h2>
|
||
|
||
<ul class="list-unstyled">
|
||
<li><a class="gtm-footer-link" href="/about/research-plan">Research Plan</a></li>
|
||
<li><a class="gtm-footer-link" href="/about/nih-heal-initiative-leadership">Leadership</a></li>
|
||
</ul>
|
||
|
||
<h2><a class="gtm-footer-link" href="/funding">Funding</a></h2>
|
||
|
||
<ul class="list-unstyled">
|
||
<li><a class="gtm-footer-link" href="/funding/awarded">Funded Projects</a></li>
|
||
<li><a class="gtm-footer-link" href="/funding/open">Open Opportunities</a></li>
|
||
<li><a class="gtm-footer-link" href="/funding/closed">Closed Opportunities</a></li>
|
||
</ul>
|
||
|
||
<h2><a class="gtm-footer-link" href="/data">Data</a></h2>
|
||
|
||
<h2><a class="gtm-footer-link" href="/news">News</a></h2>
|
||
|
||
<h2><a class="gtm-footer-link" href="/resources">Resources</a></h2>
|
||
</div>
|
||
|
||
<div class="col-6 col-md-3">
|
||
<h2><a class="gtm-footer-link" href="/research">Research</a></h2>
|
||
|
||
<ul class="list-unstyled research-list">
|
||
<li><a class="gtm-footer-link" href="/research/research-to-practice">Translation of Research to Practice for the Treatment of Opioid Addiction</a></li>
|
||
<li><a class="gtm-footer-link" href="/research/new-strategies">New Strategies to Prevent and Treat Opioid Addiction</a></li>
|
||
<li><a class="gtm-footer-link" href="/research/infants-and-children">Enhanced Outcomes for Infants and Children Exposed to Opioids</a></li>
|
||
<li><a class="gtm-footer-link" href="/research/medication-options">Novel Therapeutic Options for Opioid Use Disorder and Overdose</a></li>
|
||
<li><a class="gtm-footer-link" href="/research/clinical-research">Clinical Research in Pain Management</a></li>
|
||
<li><a class="gtm-footer-link" href="/research/preclinical-translational">Preclinical and Translational Research in Pain Management</a></li>
|
||
<li><a href="/research/cross-cutting-research">Cross-Cutting Research</a></li>
|
||
<li><a href="/research/training-next-generation-researchers">Training the Next Generation of Researchers in HEAL</a></li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="col-12 col-md-3">
|
||
<h2>Stay Connected</h2>
|
||
|
||
<p><a href="https://public.govdelivery.com/accounts/USNIHNIDA/signup/43013" target="_blank" class="signup">Sign up for news and updates.</a></p>
|
||
|
||
<div class="footer-social-media">
|
||
<h2>Follow NIH</h2>
|
||
<a aria-label="Follow us on X" class="gtm-social-twitter" href="https://twitter.com/nih" target="_blank">
|
||
<span aria-label="Twitter Icon" class="x-icon"> </span>
|
||
</a>
|
||
<a aria-label="Follow us on Instagram" class="gtm-social-instagram" href="https://www.instagram.com/nihgov" target="_blank">
|
||
<span aria-label="Instagram Icon" class="ig-icon"> </span>
|
||
</a>
|
||
<a aria-label="Follow us on Facebook" class="gtm-social-facebook" href="https://www.facebook.com/nih.gov/" target="_blank">
|
||
<span aria-label="Facebook Icon" class="fb-icon"> </span>
|
||
</a>
|
||
<a aria-label="Visit the HEAL YouTube" class="gtm-social-youtube" href="https://www.youtube.com/playlist?list=PLd_5BzGlfpgpkK12ToGD9VtxF8ClhEusZ" target="_blank">
|
||
<span aria-label="YouTube Icon" class="yt-icon"> </span>
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
<hr class="col-12" />
|
||
<div class="col-md-12 gov-links">
|
||
<ul class="list-inline">
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://www.nih.gov/">NIH Home</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://salud.nih.gov/">En Español</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://www.nih.gov/web-policies-notices">Web Policies and Notices</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html">HHS Vulnerability Disclosure</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office">Freedom of Information Act</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://www.edi.nih.gov/no-fear-act">No Fear Act</a></li>
|
||
<li class="list-inline-item"><a class="gtm-footer-link" href="https://oig.hhs.gov/">Office of Inspector General</a></li>
|
||
</ul>
|
||
|
||
<p><a class="gtm-footer-link" href="https://www.hhs.gov/">U.S. Department of Health and Human Services</a></p>
|
||
</div>
|
||
|
||
<div class="col-md-9 mx-auto gov-links">
|
||
<p>Helping to End Addiction Long-term<sup>®</sup> and NIH HEAL Initiative<sup>®</sup> are registered service marks of the Department of Health and Human Services.</p>
|
||
</div>
|
||
</div>
|
||
</footer>
|
||
|
||
|
||
<script data-cfasync="false" src="/cdn-cgi/scripts/5c5dd728/cloudflare-static/email-decode.min.js"></script><script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/40206","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"data":{"extlink":{"extTarget":true,"extTargetAppendNewWindowLabel":"(opens in a new window)","extTargetNoOverride":false,"extNofollow":false,"extTitleNoOverride":false,"extNoreferrer":false,"extFollowNoOverride":false,"extClass":"ext","extLabel":"(link is external)","extImgClass":false,"extSubdomains":true,"extExclude":"(\\.gov.*?)","extInclude":"","extCssExclude":".footer-social-media, .social-share-button, .twitter-share-button","extCssInclude":"","extCssExplicit":"","extAlert":false,"extAlertText":"This link will take you to an external web site. We are not responsible for their content.","extHideIcons":false,"mailtoClass":"0","telClass":"","mailtoLabel":"(link sends email)","telLabel":"(link is a phone number)","extUseFontAwesome":false,"extIconPlacement":"append","extPreventOrphan":false,"extFaLinkClasses":"fa fa-external-link","extFaMailtoClasses":"fa fa-envelope-o","extAdditionalLinkClasses":"","extAdditionalMailtoClasses":"","extAdditionalTelClasses":"","extFaTelClasses":"fa fa-phone","whitelistedDomains":null,"extExcludeNoreferrer":""}},"user":{"uid":0,"permissionsHash":"af5eece730f2d5aa6b0d43e1d564e85bd63161885787ef00214b14f2707a18ff"}}</script>
|
||
<script src="/themes/contrib/particle/apps/drupal/../../dist/app-drupal/assets/drupal-jquery.js?ss1xuy"></script>
|
||
<script src="/core/misc/drupalSettingsLoader.js?v=10.4.1"></script>
|
||
<script src="/core/misc/drupal.js?v=10.4.1"></script>
|
||
<script src="/core/misc/drupal.init.js?v=10.4.1"></script>
|
||
<script src="https://static.addtoany.com/menu/page.js" defer></script>
|
||
<script src="/modules/contrib/addtoany/js/addtoany.js?v=10.4.1"></script>
|
||
<script src="/modules/contrib/extlink/js/extlink.js?v=10.4.1"></script>
|
||
<script src="/themes/contrib/particle/apps/drupal/funding.js?ss1xuy"></script>
|
||
<script src="/themes/contrib/particle/apps/drupal/../../dist/app-drupal/assets/app.js?ss1xuy"></script>
|
||
<script src="/themes/contrib/particle/apps/drupal/menus.js?ss1xuy"></script>
|
||
|
||
</body>
|
||
</html>
|