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83 lines
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<title>Dr. Gerty Theresa Radnitz Cori</title>
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<p class="photoTitle">Dr. Gerty Theresa Radnitz Cori</p>
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<!-- BEGIN DISPLAY OF Transcript -->
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<p>Dr. Gerty Radnitz Cori was the first American woman
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to receive the Nobel Prize in Medicine.
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She and her husband, Dr. Carl Cori,
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shared the prize for their discovery
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of the cycle of carbohydrates in the human body.
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They had been classmates at the German University of Prague,
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where Gerty Cori was one of only a few women students.
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She received her M.D. in 1920. The couple married
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and began to work in clinics in Vienna.
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In 1922, concerned that war would break out in Europe
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for a second time, they immigrated to Buffalo, New York.
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Carl Cori accepted a position at the
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State Institute for the Study of Malignant Diseases.
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Gerty Cori joined him six months later,
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after securing a job as an Assistant Pathologist.
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Although the couple was frequently
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discouraged from working together,
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they had a dynamic research partnership
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that proved immensely profitable in their work.
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Specializing in biochemistry, the husband and wife team
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began to study how glucose is metabolized in the human body.
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In 1929, they developed their theory of
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“the cycle of carbohydrates,” now known as the Cori Cycle.
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The theory explains how carbohydrates
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supply energy to muscles during exercise,
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and then are regenerated and stored
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until needed again by the muscles.
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It was the first time the cycle of carbohydrates in the human body
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had been fully explained and understood,
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and proved especially useful for the treatment of diabetes.
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Despite their collaborative partnership
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in defining the cycle, Carl Cori initially received
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more professional recognition than Gerty Cori. He was encouraged
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to abandon the team approach and work alone.
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He was even offered a job only on the provision
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that he stop working with his wife.
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The Cori’s continued in their successful collaboration, however,
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and in 1931 moved to St. Louis.
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Carl Cori took up the post of Chair of the Pharmacology Department
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at Washington University School of Medicine.
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Over the next sixteen years, Gerty Cori
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worked alongside him as a research assistant.
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Together, they made further discoveries that clarified
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the processes of carbohydrate metabolism,
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that they had originally laid out in
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the description of the Cori Cycle.
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In the mid-1940s, Carl and Gerty Cori
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received great recognition for their work.
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Carl Cori was appointed Chair of the
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new Biochemistry Department in 1946,
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and Gerty Cori was appointed to a full professorship.
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The following year, they were awarded
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the Nobel Prize for the Cori Cycle.
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They were the first married couple
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ever to win the Nobel Prize in Medicine.</p>
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