1471 lines
46 KiB
Text
1471 lines
46 KiB
Text
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<img src="/sites/default/files/24-0591%20AoU%20Research%20Highlight%20Graphics%20January%202025_dev6_highlightSP_1980x855px.png" width="1980" height="855" alt="Una ilustración muestra dos notas autoadhesivas de diferentes colores, representando a dos medicamentos distintos que pueden ser tomados al mismo tiempo (nota verde) y dos que no deberían tomarse juntos (nota roja). Dos manos muestran a alguien a punto de tomar dos medicamentos diferentes con un vaso de agua. Un texto dice: “Los registros de salud de los participantes ayudan a revelar combinaciones inseguras de medicamentos”. El logo del Programa Científico All of Us está en la esquina inferior izquierda. " loading="lazy" typeof="foaf:Image" class="img-fluid" />
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<h2><strong>Puntos clave</strong></h2>
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<ul>
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<li>A veces, un medicamento afecta el funcionamiento de otro. Tomar ambos al mismo tiempo podría causar un problema de salud.</li>
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<li>Los investigadores científicos buscaron en informes públicos para encontrar medicamentos que podrían no ser seguros de tomar al mismo tiempo.</li>
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<li>La información de <em>All of Us</em> ayudó a confirmar que cinco pares de medicamentos podrían estar vinculados a problemas de salud potencialmente mortales.</li>
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<li>Sin embargo, estos son resultados de investigación científica y no deberían usarse para tomar decisiones médicas. Se necesita más investigación para verificar estos hallazgos.</li>
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<h2><strong>En pocas palabras</strong></h2>
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<p>A veces, tomar dos medicamentos al mismo tiempo puede causar problemas de salud. Por ejemplo, usted podría ya saber que no puede tomar aspirina si ya está tomando un medicamento anticoagulante (por ejemplo, la warfarina). Juntos, pueden provocar graves problemas de sangramiento.</p>
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<p>Hay tantos medicamentos en el mundo, y no sabemos sobre todas las combinaciones seguras o inseguras.</p>
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<p>Los investigadores científicos analizaron la información de <em>All of Us</em> y otra gran base de datos de salud para ver si podían encontrar combinaciones inseguras sobre las que no teníamos conocimiento. Encontraron cinco pares de medicamentos que podrían causar graves problemas de salud cuando se toman juntos.</p>
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<p>Los hallazgos están publicados en la revista <em>Journal of Biomedical Informatics*</em>.</p>
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<h2><strong>Buscando combinaciones inseguras</strong></h2>
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<p>Casi la mitad de las personas que viven en los Estados Unidos toman medicamentos recetados por un doctor. Muchas toman más de uno. Sin embargo, algunos medicamentos pueden afectar cómo otros medicamentos funcionan en el cuerpo. Estos efectos son conocidos como “<a href="https://medlineplus.gov/spanish/drugreactions.html">interacciones de medicamentos</a>”. Tomar dos medicamentos que interactúan entre ellos puede causar problemas de salud. Por eso, es importante saber qué medicamentos se afectan mutuamente y los problemas de salud que esto puede provocar.</p>
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<p>Para estudiar este tema, los investigadores científicos comenzaron por buscar <a href="https://www.fda.gov/drugs/fdas-adverse-event-reporting-system-faers/fda-adverse-event-reporting-system-faers-public-dashboard">informes</a> (en inglés) sobre efectos en la salud provocados por medicamentos. Buscaron los casos en que dos medicamentos tomados al mismo tiempo parecían causar un problema de salud. La búsqueda encontró docenas de pares de medicamentos que se vinculaban a problemas graves de salud.</p>
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<p>Los investigadores científicos querían revisar nuevamente los resultados. Redirigieron su atención a la información de registros electrónicos de salud (EHR, por sus siglas en inglés) de <em>All of Us</em> y del Centro Médico de la Universidad Vanderbilt (VUMC, por sus siglas en inglés). <strong>Esto incluyó información de cerca de 250,000 participantes de <em>All of Us.</em></strong></p>
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<p>Los registros electrónicos de salud contienen información sobre los medicamentos que las personas toman y sobre sus problemas de salud. Los investigadores científicos encontraron participantes que tomaban dos medicamentos al mismo tiempo y participantes que tomaban sólo uno de ellos. Luego, los investigadores científicos revisaron si los participantes que tomaban ambos medicamentos tenían más probabilidad de tener problemas de salud en comparación con aquellos que tomaban solo uno.</p>
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<p><strong>Cinco de los pares de medicamentos se vincularon con problemas de salud potencialmente mortales cuando se tomaban al mismo tiempo.</strong> Por ejemplo, un par consistió en un medicamento llamado tacrolimus, que se usa después de trasplantes de órganos, y un medicamento para el virus de inmunodeficiencia humana (VIH, o HIV, por sus siglas en inglés) llamado ritonavir. Los participantes que tomaban ambos medicamentos tenían más probabilidad de tener problemas graves en los riñones que los participantes que tomaban solo uno.</p>
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<p>Los investigadores ahora tienen una nueva forma de analizar la seguridad de los medicamentos, porque muchos participantes compartieron sus registros electrónicos de salud. Con más estudios, estos hallazgos podrían cambiar la manera en que los doctores seleccionan los medicamentos que recetan.</p>
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<h2><strong>Investigación científica para una medicina más segura</strong></h2>
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<p>Descubrir estas combinaciones perjudiciales de medicamentos es una excelente noticia. Sin embargo, el trabajo no está terminado. Este estudio no analizó medicamentos que usted puede conseguir sin receta médica. Además, otros factores (como la genética, otros problemas de salud, y opciones de estilo de vida, como el consumo de tabaco) podrían afectar la manera en que nuestros cuerpos reaccionan a los medicamentos. Estudios futuros con más información de participantes podrían tomar en cuenta estos detalles.</p>
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<p>Es importante recordar que estos son resultados de investigación científica y no deberían ser usados para tomar decisiones sobre su propio cuidado médico. <strong>Si usted tiene preguntas sobre sus medicamentos, hable con su proveedor de cuidado de salud antes de realizar cualquier cambio.</strong></p>
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<p>*Las actualizaciones para alinear esta publicación con las políticas del Programa Científico <em>All of Us </em>están aún en proceso. <em>All of Us</em> agregará un enlace a la publicación actualizada una vez que esta esté disponible.</p>
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