1258 lines
42 KiB
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1258 lines
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<p>The <em>All of Us</em> Research Program is building a dataset to help transform the future of health research by equipping researchers with expansive health data shared by a diverse participant cohort. The <em>All of Us</em> dataset is disease agnostic and can support research on many aspects of health. </p>
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<p>Thousands of health researchers are already leveraging this one-of-a-kind dataset to improve understanding of health and disease, identify opportunities to reduce disparities, and enable more precise approaches to care.</p>
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<hr>
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<p><strong>On this page:</strong></p>
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<p><a href="#Aboutresearch-hub">About the Research Hub</a><br>
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<a href="#Benefitsfor-researchers">Benefits for Researchers</a><br>
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<a href="#Guidelinesfor-applicants">Guidelines for Applicants</a><br>
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<a href="#Fundingopportunities">Funding Opportunities</a></p>
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<h2 id="Aboutresearch-hub">About the Research Hub</h2>
|
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<p>The <a href=" https://www.researchallofus.org"><i>All of Us</i> Research Hub</a> stores health data from a diverse group of participants from across the United States. Visit the Research Hub to:</p>
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<ul>
|
||
<li><strong>Use the interactive</strong> <a href="https://databrowser.researchallofus.org/">Data Browser</a>. The Data Browser provides interactive views of the publicly available <em>All of Us</em> Research Program participant data. Currently, participant-provided information, including data from surveys, wearables, physical measurements taken at the time of participant enrollment, and electronic health records (EHRs), is available.</li>
|
||
<li><strong>View</strong> <a href="https://www.researchallofus.org/data/data-snapshots/">Data Snapshots</a>. These aggregated, public-facing data snapshots provide an overview of <em>All of Us </em>Research Program participant characteristics and the types of data that the program collects from participants.</li>
|
||
<li><strong>Read about </strong><em><strong>All of Us</strong> </em><a href="https://www.researchallofus.org/data-tools/data-sources/">data sources</a> and <a href="https://www.researchallofus.org/data-tools/methods/">methods of data curation</a>.</li>
|
||
<li><strong>Find information</strong> about <a href="https://www.researchallofus.org/about/privacy-security-protocols/">privacy and security processes</a> that help keep participant data safe.</li>
|
||
</ul>
|
||
</div>
|
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<div class="col-md-4">
|
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<div class="row info-card hidden-sm hidden-xs">
|
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<h2>Get the Latest Researcher Updates</h2>
|
||
<p><a href="https://cdn.forms-content.sg-form.com/e793377f-2e71-11ef-a9aa-c6289830c400">Subscribe to the monthly <em>All of Us</em> Research Roundup newsletter</a> to stay connected with all things <em>All of Us</em> research. You’ll receive the latest <em>All of Us</em> news, funding opportunities, and more!</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
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|
||
</div>
|
||
<p><strong>The Research Hub also houses the</strong> <a href="https://www.researchallofus.org/data/workbench/">Researcher Workbench</a> <strong>platform and its suite of custom tools. </strong>The Workbench offers access to additional levels of data, workspaces, a cohort builder, and an interactive notebook environment. These tools are available to registered <em>All of Us</em> researchers.</p>
|
||
<p>Only researchers whose institutions have signed a <strong>Data Use and Registration Agreement (DURA)</strong> may register for the Researcher Workbench. This agreement must be signed by an institutional signing official. You can check if your institution has access by visiting the <a href="https://www.researchallofus.org/institutional-agreements/">Research Hub.</a> </p>
|
||
<p><a href="https://www.researchallofus.org/register/">Register for access</a>.</p>
|
||
<h2 id="Benefitsfor-researchers">Benefits for Researchers</h2>
|
||
<p>The <i>All of Us</i> Research Program’s centralized, secure, cloud-based platform allows researchers across a wide range of settings and institutions and at all stages of their careers (e.g., students, early-stage investigators) to execute rapid, hypothesis-driven research with just a computer and an Internet connection.</p>
|
||
<p><i>All of Us</i> facilitates equity in access in a deliberately inclusive way, creating a demographically diverse researcher cohort.</p>
|
||
<h3>Researcher Access to Genomic Data</h3>
|
||
<p>Within the Researcher Workbench's Controlled Tier, genomic data are integrated alongside data from surveys, physical measurements, EHRs, and wearables. The data and tools are available only to registered researchers who have taken additional steps and training to access these data. Using these datasets, researchers have opportunities to:</p>
|
||
<ul>
|
||
<li><strong>Make associations</strong> through an integrated dataset by cross-referencing biologic data with data related to participants’ environment and life circumstances</li>
|
||
<li><strong>Build upon</strong> the traditional longitudinal study model by layering dense, omic data from a large, diverse population</li>
|
||
<li><strong>Come together</strong> with other researchers from different disciplines around project-specific data analysis (through collaborative workspaces, cohort-building tools, interactive notebooks, etc.)</li>
|
||
<li><strong>Learn</strong> from sample cohorts for replicability and to help get started</li>
|
||
<li><strong>Leverage innovations</strong> of other studies and cohorts</li>
|
||
</ul>
|
||
<h2 id="Guidelinesfor-applicants">Guidelines for Applicants to Funding Opportunities</h2>
|
||
<p>To help promote equal opportunity for researchers to use <em>All of Us </em>resources, a <a href="/about/core-values">core value</a> of the program, we’ve assembled guidance for prospective applicants.</p>
|
||
<h3>Data Resources</h3>
|
||
<p>Participants share data from multiple sources. The <em>All of Us</em> <a href="https://www.researchallofus.org/data-tools/data-sources/">Research Program’s Data and Research Center</a> curates and validates these data as part of the data collection process. An NIH Letter of Support from <em>All of Us</em> is NOT necessary if a researcher is seeking funding to use the data available on the Researcher Workbench.</p>
|
||
<h3><em>All of Us</em> Resources Beyond Data</h3>
|
||
<h4><strong>Access to Biospecimens and Contact with Participants for Partnered Research Studies</strong></h4>
|
||
<p>Access to biospecimens and contact with participants for partnered research studies, or ancillary studies, are currently available only to researchers affiliated with NIH Institutes, Centers, and Offices whose proposals have been approved by the program.</p>
|
||
<p>
|
||
Researchers outside of NIH will be eligible to submit proposals in the future. At that time, <em>All of Us</em> will share guidance on how to apply and request a letter of support for funding applications. For more information about our partnered research studies, please click <a href="/funding-and-program-partners/partnered-research-studies">here</a>.</p>
|
||
<p>Questions? Contact <a href="mailto:AoUAncillaryStudies@od.nih.gov">AoUAncillaryStudies@od.nih.gov</a>.</p>
|
||
<h4><strong>Access to All of Us Operations</strong></h4>
|
||
<p>Studying the <em>All of U</em>s Research Program's structure and/or programmatic activities is not currently supported. The approximate date range when requests for access will start to be considered will be announced to help researchers prepare, along with more information on the procedures, policies, and requirements for access.</p>
|
||
<h4 id="Fundingopportunities"><strong>Funding Opportunities</strong></h4>
|
||
<p><a href="/funding-and-program-partners/funding-opportunities"><em>All of Us</em> Funding Opportunities</a></p>
|
||
<p><a href="/funding-and-program-partners/nih-funding-opportunities-researchers">NIH Funding for <em>All of Us </em>Researchers</a></p>
|
||
<p>Learn more through the <a href="https://www.researchallofus.org/discover/">research projects and publications made possible by <em>All of Us</em> data and tools</a>.</p>
|
||
<p>Questions? <a href="/about/contact-us#Researchanddatainquires">Contact us</a>.</p>
|
||
|
||
|
||
</div>
|
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|
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<span class=" related-content-title">Related Links</span>
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||
<ul>
|
||
<li><a href="https://www.nih.gov/sites/default/files/research-training/initiatives/pmi/pmi-working-group-report-20150917-2.pdf">Precision Medicine Initiative Working Group Final Report.</a></li>
|
||
<li><a href="https://www.nejm.org/doi/full/10.1056/NEJMsr1809937">NEJM Special Report: The <em>All of Us</em> Research Program</a></li>
|
||
<li><a href="/about/diversity-and-inclusion/all-us-tribal-engagement"><em>All of Us</em> Tribal Engagement</a></li>
|
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<span><strong>Last Reviewed: </strong>December 5, 2024</span>
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