I - Lipid transport and metabolism
Stats
| COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
|---|---|---|---|---|
| 135 | 2,291 | 290,846 | 309.0 | 128 |
| Organism | Protein | COG | Cat | Annotation |
|---|---|---|---|---|
| 2223 | 2665 | COG0020 | I | Undecaprenyl pyrophosphate synthase |
| 1464 | 1584 | COG0109 | H I | Polyprenyltransferase (heme O synthase) |
| 1713 | 8003 | COG0183 | I | Acetyl-CoA acetyltransferase |
| 2045 | 6642 | COG0204 | I | 1-acyl-sn-glycerol-3-phosphate acyltransferase |
| 2027 | 6872 | COG0236 | I | Acyl carrier protein |
| 1741 | 1745 | COG0245 | I | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| 1971 | 4902 | COG0304 | I Q | 3-oxoacyl-(acyl-carrier-protein) synthase |
| 1894 | 12280 | COG0318 | I | O-succinylbenzoic acid-CoA ligase MenE or related acyl-CoA synthetase (AMP-forming) |
| 1955 | 2368 | COG0331 | I | Malonyl CoA-acyl carrier protein transacylase |
| 1926 | 3628 | COG0332 | I | 3-oxoacyl-[acyl-carrier-protein] synthase III |
| 1513 | 1770 | COG0344 | I | Phospholipid biosynthesis protein PlsY, probable glycerol-3-phosphate acyltransferase |
| 1747 | 4807 | COG0365 | I | Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase |
| 1133 | 1522 | COG0386 | V I | Thioredoxin/glutathione peroxidase BtuE, reduces lipid peroxides |
| 1563 | 1662 | COG0416 | I | Acyl-ACP:phosphate acyltransferase (fatty acid/phospholipid biosynthesis) |
| 1085 | 1579 | COG0439 | I | Biotin carboxylase |
| 1763 | 2591 | COG0511 | I | Biotin carboxyl carrier protein |
| 2065 | 3742 | COG0558 | I | Phosphatidylglycerophosphate synthase |
| 1925 | 1930 | COG0575 | I | CDP-diglyceride synthetase |
| 1748 | 3650 | COG0584 | I | Glycerophosphoryl diester phosphodiesterase |
| 1425 | 1856 | COG0623 | I | Enoyl-[acyl-carrier-protein] reductase FabI |
| 1495 | 5288 | COG0657 | I | Acetyl esterase/lipase |
| 1572 | 2692 | COG0671 | I | Membrane-associated phospholipid phosphatase |
| 1444 | 1610 | COG0688 | I | Phosphatidylserine decarboxylase |
| 1519 | 1593 | COG0736 | I | Phosphopantetheinyl transferase (holo-ACP synthase) |
| 1706 | 1716 | COG0743 | I | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| 1754 | 1859 | COG0761 | I | 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH |
| 1744 | 3018 | COG0764 | I | 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase |
| 1642 | 1810 | COG0777 | I | Acetyl-CoA carboxylase beta subunit |
| 1190 | 1279 | COG0818 | I | Diacylglycerol kinase |
| 1742 | 1767 | COG0821 | I | 4-hydroxy-3-methylbut-2-enyl diphosphate synthase IspG/GcpE |
| 1835 | 4867 | COG0824 | I | Acyl-CoA thioesterase FadM |
| 1639 | 1702 | COG0825 | I | Acetyl-CoA carboxylase alpha subunit |
| 2054 | 15634 | COG1012 | I | Acyl-CoA reductase or other NAD-dependent aldehyde dehydrogenase |
| 1247 | 2306 | COG1022 | I | Long-chain acyl-CoA synthetase (AMP-forming) |
| 1613 | 12715 | COG1024 | I | Enoyl-CoA hydratase/carnithine racemase |
| 2182 | 35218 | COG1028 | I | NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family |
| 748 | 1302 | COG1075 | I | Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold |
| 1794 | 1913 | COG1154 | H I | Deoxyxylulose-5-phosphate synthase |
| 1387 | 1722 | COG1183 | I | Phosphatidylserine synthase |
| 1766 | 1935 | COG1211 | I | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
| 345 | 410 | COG1213 | I | Choline kinase |
| 1556 | 4678 | COG1250 | I | 3-hydroxyacyl-CoA dehydrogenase |
| 561 | 612 | COG1257 | I | Hydroxymethylglutaryl-CoA reductase |
| 452 | 534 | COG1260 | I | Myo-inositol-1-phosphate synthase |
| 995 | 1057 | COG1267 | I | Phosphatidylglycerophosphatase A |
| 1328 | 2098 | COG1304 | C I R | FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase |
| 627 | 1721 | COG1307 | I | Fatty acid-binding protein DegV |
| 633 | 985 | COG1398 | I | Fatty-acid desaturase |
| 839 | 1020 | COG1443 | I | Isopentenyldiphosphate isomerase |
| 582 | 646 | COG1461 | I | Fatty acid kinase |
| 1811 | 3879 | COG1502 | I | Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase |
| 1293 | 2059 | COG1560 | I | Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) |
| 1183 | 1862 | COG1562 | I | Phytoene/squalene synthetase |
| 475 | 743 | COG1577 | I | Mevalonate kinase |
| 1444 | 2616 | COG1597 | I R | Phosphatidylglycerol kinase, diacylglycerol kinase family |
| 1307 | 2033 | COG1607 | I | Acyl-CoA hydrolase |
| 197 | 202 | COG1608 | I | Isopentenyl phosphate kinase |
| 398 | 430 | COG1646 | I | Glycerol-1-phosphate heptaprenyltransferase |
| 329 | 418 | COG1657 | I | Terpene cyclase SqhC |
| 228 | 252 | COG1679 | I | Mevalonate 5-phosphate dehydratase subunit 1, aconitase superfamily (modified mevalonate pathway) |
| 229 | 249 | COG1786 | I | Mevalonate 5-phosphate dehydratase subunit 2, swiveling domain (modified mevalonate pathway) |
| 1009 | 1572 | COG1788 | I | Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit |
| 1053 | 4577 | COG1804 | I | Crotonobetainyl-CoA:carnitine CoA-transferase CaiB and related acyl-CoA transferases |
| 1055 | 2228 | COG1884 | I | Methylmalonyl-CoA mutase, N-terminal domain/subunit |
| 451 | 881 | COG1887 | M I | CDP-glycerol glycerophosphotransferase, TagB/SpsB family |
| 508 | 993 | COG1924 | I | Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) |
| 650 | 969 | COG1946 | I | Acyl-CoA thioesterase |
| 1797 | 1808 | COG1947 | I | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase |
| 1715 | 16202 | COG1960 | I | Acyl-CoA dehydrogenase related to the alkylation response protein AidB |
| 277 | 309 | COG1964 | H I | Archaeal tetraether lipid synthase/C-terminal domain of the GTP 3',8'-cyclase MoaA, radical SAM superfamily |
| 1993 | 2211 | COG1968 | I | Undecaprenyl pyrophosphate phosphatase |
| 1250 | 4509 | COG2030 | I | Acyl-CoA dehydratase PaaZ |
| 273 | 308 | COG2031 | I | Short chain fatty acids transporter |
| 1017 | 1589 | COG2057 | I | Acyl-CoA:acetate/3-ketoacid CoA transferase, beta subunit |
| 834 | 1396 | COG2067 | I | Long-chain fatty acid transport protein |
| 71 | 81 | COG2074 | G I | 2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase |
| 1459 | 3779 | COG2084 | I | 3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase |
| 94 | 104 | COG2134 | I | CDP-diacylglycerol pyrophosphatase |
| 1095 | 2024 | COG2185 | I | Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) |
| 1362 | 3019 | COG2230 | I | Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases |
| 948 | 1340 | COG2246 | I | Putative flippase GtrA (transmembrane translocase of bactoprenol-linked glucose) |
| 1627 | 3847 | COG2267 | I | Lysophospholipase, alpha-beta hydrolase superfamily |
| 463 | 957 | COG2272 | I | Carboxylesterase type B |
| 1147 | 3832 | COG2303 | I R | Choline dehydrogenase or related flavoprotein |
| 317 | 326 | COG2324 | I | Carotenoid 2',3'-hydratase CruF |
| 1694 | 5757 | COG2755 | D I | Lysophospholipase L1 or related esterase. Includes spore coat protein LipC/YcsK |
| 476 | 616 | COG2898 | I | Bifunctional lysylphosphatidylglycerol synthetase/flippase MprF |
| 401 | 486 | COG2930 | I | Phosphatidylinositol-binding SYLF domain, Ysc84/FYVE family |
| 371 | 413 | COG2937 | I | Glycerol-3-phosphate O-acyltransferase |
| 784 | 1845 | COG3000 | I | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily |
| 243 | 251 | COG3007 | I | Trans-2-enoyl-CoA reductase |
| 372 | 374 | COG3124 | I | Acyl carrier protein phosphodiesterase |
| 925 | 2054 | COG3239 | I | Fatty acid desaturase |
| 286 | 408 | COG3240 | I | Phospholipase/lecithinase/hemolysin, may have acyltransferase activity |
| 662 | 1299 | COG3243 | I | Poly-beta-hydroxybutyrate synthase |
| 430 | 559 | COG3255 | I | Putative sterol carrier protein, contains SCP2 domain |
| 118 | 121 | COG3356 | I | Predicted membrane-associated lipid hydrolase, neutral ceramidase superfamily |
| 356 | 371 | COG3407 | I | Mevalonate pyrophosphate decarboxylase |
| 441 | 526 | COG3425 | I | 3-hydroxy-3-methylglutaryl CoA synthase |
| 245 | 333 | COG3433 | I Q | Acyl carrier protein/domain |
| 137 | 142 | COG3470 | M I | Uncharacterized conserved protein probably involved in high-affinity Fe2+ transport |
| 169 | 260 | COG3475 | I | Phosphorylcholine metabolism protein LicD |
| 50 | 56 | COG3675 | I | Predicted lipase |
| 159 | 171 | COG3697 | H I | Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) |
| 305 | 314 | COG3714 | I | Membrane lysoplasmalogenase (glycerophospholipid hydrolase), YhhN family |
| 209 | 259 | COG3777 | I | Hydroxyacyl-ACP dehydratase HTD2, hotdog domain |
| 917 | 3268 | COG3832 | I | Chalcone/flavanone-binding protein YndB, AHSA1/START/SRPBCC domain |
| 190 | 226 | COG3882 | I | Predicted enzyme involved in methoxymalonyl-ACP biosynthesis |
| 322 | 342 | COG3884 | I | Acyl-ACP thioesterase |
| 13 | 13 | COG3890 | I | Phosphomevalonate kinase |
| 372 | 468 | COG3963 | I | Phosphatidylethanolamine N-methyltransferase |
| 230 | 276 | COG3967 | M I | Short-chain dehydrogenase involved in D-alanine esterification of teichoic acids |
| 223 | 233 | COG4247 | I | 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) |
| 220 | 224 | COG4281 | I | Acyl-CoA-binding protein |
| 592 | 717 | COG4395 | I | Predicted lipid-binding transport protein, Tim44 family |
| 213 | 222 | COG4539 | I | 2-hydroxy fatty acid dioxygenase MPO1 (alpha-oxidation of fatty acids) |
| 343 | 410 | COG4553 | I | Poly-beta-hydroxyalkanoate depolymerase |
| 429 | 510 | COG4667 | I | Predicted phospholipase, patatin/cPLA2 family |
| 348 | 467 | COG4670 | I | Acyl CoA:acetate/3-ketoacid CoA transferase |
| 216 | 355 | COG4677 | G I | Pectin methylesterase and related acyl-CoA thioesterases |
| 270 | 291 | COG4706 | I | Predicted 3-hydroxylacyl-ACP dehydratase, HotDog domain |
| 73 | 106 | COG4750 | M I | CTP:phosphocholine cytidylyltransferase LicC |
| 1868 | 3964 | COG4770 | I | Acetyl/propionyl-CoA carboxylase, alpha subunit |
| 79 | 86 | COG4781 | I | Membrane-anchored glycerophosphoryl diester phosphodiesterase (GDPDase), membrane domain |
| 1395 | 3025 | COG4799 | I | Acetyl-CoA carboxylase, carboxyltransferase component |
| 309 | 368 | COG4850 | I | Phosphatidate phosphatase APP1 |
| 196 | 220 | COG4894 | I | Putative phospholipid scramblase YxjI, Tubby2 superfamily |
| 39 | 40 | COG4981 | I | Enoyl reductase domain of yeast-type fatty acid synthase |
| 41 | 42 | COG4982 | I | 3-oxoacyl-ACP reductase domain of yeast-type fatty acid synthase FAS1 |
| 41 | 46 | COG5029 | O I | Prenyltransferase, beta subunit |
| 34 | 35 | COG5050 | I | sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases |
| 21 | 22 | COG5083 | I | Phosphatidate phosphatase PAH1, contains Lipin and LNS2 domains. can be involved in plasmid maintenance |
| 52 | 56 | COG5274 | C I | Cytochrome b involved in lipid metabolism |
| 174 | 202 | COG5331 | O I | Predicted lipid metabolism protein, MAPEG family |
| 162 | 171 | COG5379 | I | S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase |