Name: rs11202592
Published: September 21, 2022
License: Open Access

Welcome to the Reference SNP (rs) Report

All alleles are reported in the Forward orientation. Click on the Variant Details tab for details on Genomic Placement, Gene, and Amino Acid changes. HGVS names are in the HGVS tab.

Reference SNP (rs) Report

This page reports data for a single dbSNP Reference SNP variation (RefSNP or rs) from the new redesigned dbSNP build.
Top of the page reports a concise summary for the rs, with more specific details included in the corresponding tabs below.
All alleles are reported in the Forward orientation. Use the Genomic View to inspect the nucleotides flanking the variant, and its neighbors.
For more information see Help documentation.

rs11202592

Current Build 156

Released September 21, 2022

Organism: Homo sapiens
Position: chr10:87864461 (GRCh38.p14) Help
The anchor position for this RefSNP. Includes all nucleotides potentially affected by this change, thus it can differ from HGVS, which is right-shifted. See here for details.
Alleles: C>G / C>T
Variation Type: SNV Single Nucleotide Variation
Frequency: G=0.002509 (664/264690, TOPMED)
G=0.003821 (961/251482, GnomAD_exome)
G=0.001390 (195/140278, GnomAD) (+ 15 more)
G=0.003624 (440/121404, ExAC)
G=0.00020 (10/49260, ALFA)
G=0.03564 (1007/28258, 14KJPN)
G=0.03508 (588/16760, 8.3KJPN)
G=0.00015 (2/13006, GO-ESP)
G=0.0097 (62/6404, 1000G_30x)
G=0.0110 (55/5008, 1000G)
G=0.0002 (1/4480, Estonian)
G=0.0003 (1/3854, ALSPAC)
G=0.0000 (0/3708, TWINSUK)
G=0.0407 (119/2922, KOREAN)
G=0.0251 (46/1832, Korea1K)
G=0.073 (45/613, Vietnamese)
C=0.50 (7/14, SGDP_PRJ)
G=0.50 (7/14, SGDP_PRJ)

Clinical Significance: Reported in ClinVar
Gene : Consequence: PTEN : Missense Variant
KLLN : 2KB Upstream Variant
Publications: 7 citations
Genomic View: See rs on genome

ALFA Allele Frequency
The ALFA project provide aggregate allele frequency from dbGaP. More information is available on the project page including descriptions, data access, and terms of use.

Release Version: 20231103111315

Population	Group	Sample Size	Ref Allele	Alt Allele	Ref HMOZ	HTRZ	HWEP
Total	Global	49260	C=0.99980	G=0.00020	0.999594	0.000406	0
European	Sub	37246	C=0.99992	G=0.00008	0.999839	0.000161	0
African	Sub	3560	C=1.0000	G=0.0000	1.0	0.0	N/A
African Others	Sub	122	C=1.000	G=0.000	1.0	0.0	N/A
African American	Sub	3438	C=1.0000	G=0.0000	1.0	0.0	N/A
Asian	Sub	168	C=0.976	G=0.024	0.952381	0.047619	0
East Asian	Sub	112	C=0.973	G=0.027	0.946429	0.053571	0
Other Asian	Sub	56	C=0.98	G=0.02	0.964286	0.035714	0
Latin American 1	Sub	500	C=1.000	G=0.000	1.0	0.0	N/A
Latin American 2	Sub	628	C=1.000	G=0.000	1.0	0.0	N/A
South Asian	Sub	98	C=0.99	G=0.01	0.979592	0.020408	0
Other	Sub	7060	C=0.9997	G=0.0003	0.999433	0.000567	0

Frequency tab displays a table of the reference and alternate allele frequencies reported by various studies and populations. Table lines, where Population="Global" refer to the entire study population, whereas lines, where Group="Sub", refer to a study-specific population subgroupings (i.e. AFR, CAU, etc.), if available. Frequency for the alternate allele (Alt Allele) is a ratio of samples observed-to-total, where the numerator (observed samples) is the number of chromosomes in the study with the minor allele present (found in "Sample size", where Group="Sub"), and the denominator (total samples) is the total number of all chromosomes in the study for the variant (found in "Sample size", where Group="Study-wide" and Population="Global").

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Study	Population	Group	Sample Size	Ref Allele	Alt Allele
TopMed	Global	Study-wide	264690	C=0.997491	G=0.002509
gnomAD - Exomes	Global	Study-wide	251482	C=0.996179	G=0.003821
gnomAD - Exomes	European	Sub	135408	C=0.999897	G=0.000103
gnomAD - Exomes	Asian	Sub	49010	C=0.98088	G=0.01912
gnomAD - Exomes	American	Sub	34592	C=0.99997	G=0.00003
gnomAD - Exomes	African	Sub	16254	C=1.00000	G=0.00000
gnomAD - Exomes	Ashkenazi Jewish	Sub	10080	C=1.00000	G=0.00000
gnomAD - Exomes	Other	Sub	6138	C=0.9985	G=0.0015
gnomAD - Genomes	Global	Study-wide	140278	C=0.998610	G=0.001390
gnomAD - Genomes	European	Sub	75960	C=0.99988	G=0.00012
gnomAD - Genomes	African	Sub	42042	C=0.99998	G=0.00002
gnomAD - Genomes	American	Sub	13670	C=0.99971	G=0.00029
gnomAD - Genomes	Ashkenazi Jewish	Sub	3322	C=1.0000	G=0.0000
gnomAD - Genomes	East Asian	Sub	3132	C=0.9425	G=0.0575
gnomAD - Genomes	Other	Sub	2152	C=0.9995	G=0.0005
ExAC	Global	Study-wide	121404	C=0.996376	G=0.003624
ExAC	Europe	Sub	73354	C=0.99989	G=0.00011
ExAC	Asian	Sub	25160	C=0.98303	G=0.01697
ExAC	American	Sub	11578	C=0.99983	G=0.00017
ExAC	African	Sub	10404	C=1.00000	G=0.00000
ExAC	Other	Sub	908	C=0.997	G=0.003
Allele Frequency Aggregator	Total	Global	49260	C=0.99980	G=0.00020
Allele Frequency Aggregator	European	Sub	37246	C=0.99992	G=0.00008
Allele Frequency Aggregator	Other	Sub	7060	C=0.9997	G=0.0003
Allele Frequency Aggregator	African	Sub	3560	C=1.0000	G=0.0000
Allele Frequency Aggregator	Latin American 2	Sub	628	C=1.000	G=0.000
Allele Frequency Aggregator	Latin American 1	Sub	500	C=1.000	G=0.000
Allele Frequency Aggregator	Asian	Sub	168	C=0.976	G=0.024
Allele Frequency Aggregator	South Asian	Sub	98	C=0.99	G=0.01
14KJPN	JAPANESE	Study-wide	28258	C=0.96436	G=0.03564
8.3KJPN	JAPANESE	Study-wide	16760	C=0.96492	G=0.03508
GO Exome Sequencing Project	Global	Study-wide	13006	C=0.99985	G=0.00015
GO Exome Sequencing Project	European American	Sub	8600	C=0.9998	G=0.0002
GO Exome Sequencing Project	African American	Sub	4406	C=1.0000	G=0.0000
1000Genomes_30x	Global	Study-wide	6404	C=0.9903	G=0.0097
1000Genomes_30x	African	Sub	1786	C=1.0000	G=0.0000
1000Genomes_30x	Europe	Sub	1266	C=1.0000	G=0.0000
1000Genomes_30x	South Asian	Sub	1202	C=0.9967	G=0.0033
1000Genomes_30x	East Asian	Sub	1170	C=0.9504	G=0.0496
1000Genomes_30x	American	Sub	980	C=1.000	G=0.000
1000Genomes	Global	Study-wide	5008	C=0.9890	G=0.0110
1000Genomes	African	Sub	1322	C=1.0000	G=0.0000
1000Genomes	East Asian	Sub	1008	C=0.9494	G=0.0506
1000Genomes	Europe	Sub	1006	C=1.0000	G=0.0000
1000Genomes	South Asian	Sub	978	C=0.996	G=0.004
1000Genomes	American	Sub	694	C=1.000	G=0.000
Genetic variation in the Estonian population	Estonian	Study-wide	4480	C=0.9998	G=0.0002
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.9997	G=0.0003
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=1.0000	G=0.0000
KOREAN population from KRGDB	KOREAN	Study-wide	2922	C=0.9593	G=0.0407
Korean Genome Project	KOREAN	Study-wide	1832	C=0.9749	G=0.0251
A Vietnamese Genetic Variation Database	Global	Study-wide	613	C=0.927	G=0.073
SGDP_PRJ	Global	Study-wide	14	C=0.50	G=0.50

Variant Details tab shows known variant placements on genomic sequences: chromosomes (NC_), RefSeqGene, pseudogenes or genomic regions (NG_), and in a separate table: on transcripts (NM_) and protein sequences (NP_). The corresponding transcript and protein locations are listed in adjacent lines, along with molecular consequences from Sequence Ontology. When no protein placement is available, only the transcript is listed. Column "Codon[Amino acid]" shows the actual base change in the format of "Reference > Alternate" allele, including the nucleotide codon change in transcripts, and the amino acid change in proteins, respectively, allowing for known ribosomal slippage sites. To view nucleotides adjacent to the variant use the Genomic View at the bottom of the page - zoom into the sequence until the nucleotides around the variant become visible.

Genomic Placements

Sequence name	Change
GRCh38.p14 chr 10	NC_000010.11:g.87864461C>G
GRCh38.p14 chr 10	NC_000010.11:g.87864461C>T
GRCh37.p13 chr 10	NC_000010.10:g.89624218C>G
GRCh37.p13 chr 10	NC_000010.10:g.89624218C>T
PTEN RefSeqGene (LRG_311)	NG_007466.2:g.6023C>G
PTEN RefSeqGene (LRG_311)	NG_007466.2:g.6023C>T
GRCh38.p14 chr 10 fix patch HG2334_PATCH	NW_013171807.1:g.80284C>G
GRCh38.p14 chr 10 fix patch HG2334_PATCH	NW_013171807.1:g.80284C>T
KLLN RefSeqGene (LRG_1087)	NG_033079.1:g.3977G>C
KLLN RefSeqGene (LRG_1087)	NG_033079.1:g.3977G>A

Gene: PTEN, phosphatase and tensin homolog (plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
PTEN transcript variant 3	NM_001304718.2:c.-714=	N/A	5 Prime UTR Variant
PTEN transcript variant 1	NM_000314.8:c.-9=	N/A	5 Prime UTR Variant
PTEN transcript variant 2	NM_001304717.5:c.511C>G	L [CTC] > V [GTC]	Coding Sequence Variant
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN-L	NP_001291646.4:p.Leu171Val	L (Leu) > V (Val)	Missense Variant
PTEN transcript variant 2	NM_001304717.5:c.511C>T	L [CTC] > F [TTC]	Coding Sequence Variant
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN-L	NP_001291646.4:p.Leu171Phe	L (Leu) > F (Phe)	Missense Variant

Gene: KLLN, killin, p53 regulated DNA replication inhibitor (minus strand) : 2KB Upstream Variant

Molecule type	Change	Amino acid[Codon]	SO Term
KLLN transcript	NM_001126049.2:c.	N/A	Upstream Transcript Variant

Clinical Significance tab shows a list of clinical significance entries from ClinVar associated with the variation, per allele. Click on the RCV accession (i.e. RCV000001615.2) or Allele ID (i.e. 12274) to access full ClinVar report.

Allele: G (allele ID: 98715 )

ClinVar Accession	Disease Names	Clinical Significance
RCV000078600.18	not specified	Benign
RCV000131696.3	Hereditary cancer-predisposing syndrome	Benign
RCV000203697.10	PTEN hamartoma tumor syndrome	Benign
RCV000409463.2	Cowden syndrome 1	Benign
RCV001357743.2	Malignant tumor of breast	Benign
RCV001647049.3	not provided	Benign

Allele: T (allele ID: 1320716 )

ClinVar Accession	Disease Names	Clinical Significance
RCV001801050.1	not provided	Uncertain-Significance

Aliases tab displays HGVS names representing the variant placements and allele changes on genomic, transcript and protein sequences, per allele. HGVS name is an expression for reporting sequence accession and version, sequence type, position, and allele change. The column "Note" can have two values: "diff" means that there is a difference between the reference allele (variation interval) at the placement reported in HGVS name and the reference alleles reported in other HGVS names, and "rev" means that the sequence of this variation interval at the placement reported in HGVS name is in reverse orientation to the sequence(s) of this variation in other HGVS names not labeled as "rev".

Placement	C=	G	T
GRCh38.p14 chr 10	NC_000010.11:g.87864461=	NC_000010.11:g.87864461C>G	NC_000010.11:g.87864461C>T
GRCh37.p13 chr 10	NC_000010.10:g.89624218=	NC_000010.10:g.89624218C>G	NC_000010.10:g.89624218C>T
PTEN RefSeqGene (LRG_311)	NG_007466.2:g.6023=	NG_007466.2:g.6023C>G	NG_007466.2:g.6023C>T
PTEN transcript variant 1	NM_000314.8:c.-9=	NM_000314.8:c.-9C>G	NM_000314.8:c.-9C>T
PTEN transcript variant 1	NM_000314.7:c.-9=	NM_000314.7:c.-9C>G	NM_000314.7:c.-9C>T
PTEN transcript variant 1	NM_000314.6:c.-9=	NM_000314.6:c.-9C>G	NM_000314.6:c.-9C>T
PTEN transcript variant 1	NM_000314.5:c.-9=	NM_000314.5:c.-9C>G	NM_000314.5:c.-9C>T
PTEN transcript	NM_000314.4:c.-9=	NM_000314.4:c.-9C>G	NM_000314.4:c.-9C>T
PTEN transcript variant 2	NM_001304717.5:c.511=	NM_001304717.5:c.511C>G	NM_001304717.5:c.511C>T
PTEN transcript variant 1	NM_001304717.4:c.511=	NM_001304717.4:c.511C>G	NM_001304717.4:c.511C>T
PTEN transcript variant 1	NM_001304717.3:c.511=	NM_001304717.3:c.511C>G	NM_001304717.3:c.511C>T
PTEN transcript variant 1	NM_001304717.2:c.511=	NM_001304717.2:c.511C>G	NM_001304717.2:c.511C>T
PTEN transcript variant 1	NM_001304717.1:c.511=	NM_001304717.1:c.511C>G	NM_001304717.1:c.511C>T
PTEN transcript variant 3	NM_001304718.2:c.-714=	NM_001304718.2:c.-714C>G	NM_001304718.2:c.-714C>T
PTEN transcript variant 2	NM_001304718.1:c.-714=	NM_001304718.1:c.-714C>G	NM_001304718.1:c.-714C>T
GRCh38.p14 chr 10 fix patch HG2334_PATCH	NW_013171807.1:g.80284=	NW_013171807.1:g.80284C>G	NW_013171807.1:g.80284C>T
KLLN RefSeqGene (LRG_1087)	NG_033079.1:g.3977=	NG_033079.1:g.3977G>C	NG_033079.1:g.3977G>A
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform PTEN-L	NP_001291646.4:p.Leu171=	NP_001291646.4:p.Leu171Val	NP_001291646.4:p.Leu171Phe

Submissions tab displays variations originally submitted to dbSNP, now supporting this RefSNP cluster (rs). We display Submitter handle, Submission identifier, Date and Build number, when the submission appeared for the first time. Direct submissions to dbSNP have Submission ID in the form of an ss-prefixed number (ss#). Other supporting variations are listed in the table without ss#.

44 SubSNP, 17 Frequency, 7 ClinVar submissions

No	Submitter	Submission ID	Date (Build)
1	SC_SNP	ss16023862	Feb 27, 2004 (120)
2	SC_SNP	ss18430194	Feb 27, 2004 (120)
3	IMCJ-GDT	ss28503391	Sep 24, 2004 (126)
4	EGP_SNPS	ss38349671	Mar 10, 2006 (126)
5	SNP500CANCER	ss48296534	Mar 10, 2006 (126)
6	1000GENOMES	ss336288984	May 09, 2011 (134)
7	GMI	ss475759981	May 04, 2012 (137)
8	ILLUMINA	ss534648741	Sep 08, 2015 (146)
9	NHLBI-ESP	ss712961380	Apr 25, 2013 (138)
10	JMKIDD_LAB	ss1067514454	Aug 21, 2014 (142)
11	1000GENOMES	ss1338437068	Aug 21, 2014 (142)
12	EVA_UK10K_ALSPAC	ss1625093241	Apr 01, 2015 (144)
13	EVA_UK10K_TWINSUK	ss1668087274	Apr 01, 2015 (144)
14	EVA_EXAC	ss1689987190	Apr 01, 2015 (144)
15	HUMAN_LONGEVITY	ss2176762875	Dec 20, 2016 (150)
16	GRF	ss2698815670	Nov 08, 2017 (151)
17	GNOMAD	ss2738382452	Nov 08, 2017 (151)
18	GNOMAD	ss2748430598	Nov 08, 2017 (151)
19	GNOMAD	ss2891600731	Nov 08, 2017 (151)
20	ILLUMINA	ss3021260730	Nov 08, 2017 (151)
21	ILLUMINA	ss3626499341	Oct 12, 2018 (152)
22	OMUKHERJEE_ADBS	ss3646412915	Oct 12, 2018 (152)
23	ILLUMINA	ss3651618436	Oct 12, 2018 (152)
24	EGCUT_WGS	ss3674298544	Jul 13, 2019 (153)
25	ILLUMINA	ss3725175696	Jul 13, 2019 (153)
26	EVA	ss3748411500	Jul 13, 2019 (153)
27	KHV_HUMAN_GENOMES	ss3813778969	Jul 13, 2019 (153)
28	EVA	ss3824535866	Apr 26, 2020 (154)
29	SGDP_PRJ	ss3874732512	Apr 26, 2020 (154)
30	KRGDB	ss3922848181	Apr 26, 2020 (154)
31	KOGIC	ss3968369668	Apr 26, 2020 (154)
32	TOPMED	ss4860996997	Apr 26, 2021 (155)
33	TOMMO_GENOMICS	ss5198760000	Apr 26, 2021 (155)
34	1000G_HIGH_COVERAGE	ss5284926897	Oct 16, 2022 (156)
35	TRAN_CS_UWATERLOO	ss5314429170	Oct 16, 2022 (156)
36	EVA	ss5395032269	Oct 16, 2022 (156)
37	HUGCELL_USP	ss5480403035	Oct 16, 2022 (156)
38	1000G_HIGH_COVERAGE	ss5579321440	Oct 16, 2022 (156)
39	SANFORD_IMAGENETICS	ss5649794713	Oct 16, 2022 (156)
40	TOMMO_GENOMICS	ss5744915685	Oct 16, 2022 (156)
41	YY_MCH	ss5811752600	Oct 16, 2022 (156)
42	EVA	ss5879897544	Oct 16, 2022 (156)
43	EVA	ss5936027900	Oct 16, 2022 (156)
44	EVA	ss5941075481	Oct 16, 2022 (156)
45	1000Genomes	NC_000010.10 - 89624218	Oct 12, 2018 (152)
46	1000Genomes_30x	NC_000010.11 - 87864461	Oct 16, 2022 (156)
47	The Avon Longitudinal Study of Parents and Children	NC_000010.10 - 89624218	Oct 12, 2018 (152)
48	Genetic variation in the Estonian population	NC_000010.10 - 89624218	Oct 12, 2018 (152)
49	ExAC	NC_000010.10 - 89624218	Oct 12, 2018 (152)
50	gnomAD - Genomes	NC_000010.11 - 87864461	Apr 26, 2021 (155)
51	gnomAD - Exomes	NC_000010.10 - 89624218	Jul 13, 2019 (153)
52	GO Exome Sequencing Project	NC_000010.10 - 89624218	Oct 12, 2018 (152)
53	KOREAN population from KRGDB	NC_000010.10 - 89624218	Apr 26, 2020 (154)
54	Korean Genome Project	NC_000010.11 - 87864461	Apr 26, 2020 (154)
55	SGDP_PRJ	NC_000010.10 - 89624218	Apr 26, 2020 (154)
56	8.3KJPN	NC_000010.10 - 89624218	Apr 26, 2021 (155)
57	14KJPN	NC_000010.11 - 87864461	Oct 16, 2022 (156)
58	TopMed	NC_000010.11 - 87864461	Apr 26, 2021 (155)
59	UK 10K study - Twins	NC_000010.10 - 89624218	Oct 12, 2018 (152)
60	A Vietnamese Genetic Variation Database	NC_000010.10 - 89624218	Jul 13, 2019 (153)
61	ALFA	NC_000010.11 - 87864461	Apr 26, 2021 (155)
62	ClinVar	RCV000078600.18	Oct 16, 2022 (156)
63	ClinVar	RCV000131696.3	Oct 16, 2022 (156)
64	ClinVar	RCV000203697.10	Oct 16, 2022 (156)
65	ClinVar	RCV000409463.2	Oct 16, 2022 (156)
66	ClinVar	RCV001357743.2	Oct 16, 2022 (156)
67	ClinVar	RCV001647049.3	Oct 16, 2022 (156)
68	ClinVar	RCV001801050.1	Oct 16, 2022 (156)

History tab displays RefSNPs (Associated ID) from previous builds (Build) that now support the current RefSNP, and the dates, when the history was updated for each Associated ID (History Updated).

Associated ID	History Updated (Build)
rs17849089	Mar 10, 2006 (126)

Added to this RefSNP Cluster:

Submission IDs	Observation SPDI	Canonical SPDI	Source RSIDs
ss475759981	NC_000010.9:89614197:C:G	NC_000010.11:87864460:C:G	(self)
50861369, 28232193, 20036792, 214591, 7581372, 993552, 30025575, 26749492, 56729307, 28232193, 6269821, ss336288984, ss534648741, ss712961380, ss1067514454, ss1338437068, ss1625093241, ss1668087274, ss1689987190, ss2698815670, ss2738382452, ss2748430598, ss2891600731, ss3021260730, ss3626499341, ss3646412915, ss3651618436, ss3674298544, ss3748411500, ss3824535866, ss3874732512, ss3922848181, ss5198760000, ss5395032269, ss5649794713, ss5936027900, ss5941075481	NC_000010.10:89624217:C:G	NC_000010.11:87864460:C:G	(self)
RCV000078600.18, RCV000131696.3, RCV000203697.10, RCV000409463.2, RCV001357743.2, RCV001647049.3, 66847375, 359381869, 24747669, 78752789, 76542652, 8339095084, ss2176762875, ss3725175696, ss3813778969, ss3968369668, ss4860996997, ss5284926897, ss5314429170, ss5480403035, ss5579321440, ss5744915685, ss5811752600, ss5879897544	NC_000010.11:87864460:C:G	NC_000010.11:87864460:C:G	(self)
ss16023862, ss18430194	NT_030059.11:8372733:C:G	NC_000010.11:87864460:C:G	(self)
ss28503391, ss38349671, ss48296534	NT_030059.13:40428681:C:G	NC_000010.11:87864460:C:G	(self)
RCV001801050.1	NC_000010.11:87864460:C:T	NC_000010.11:87864460:C:T

Publications tab displays PubMed articles citing the variation as a listing of PMID, Title, Author, Year, Journal, ordered by Year, descending.

7 citations for rs11202592

PMID	Title	Author	Year	Journal
14623110	Association of the polymorphisms in the 5'-untranslated region of PTEN gene with type 2 diabetes in a Japanese population.	Ishihara H et al.	2003	FEBS letters
23315997	RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs.	Sabarinathan R et al.	2013	Human mutation
23757202	Free the data: one laboratory's approach to knowledge-based genomic variant classification and preparation for EMR integration of genomic data.	Bean LJ et al.	2013	Human mutation
24632578	Combined effects of genetic variants of the PTEN, AKT1, MDM2 and p53 genes on the risk of nasopharyngeal carcinoma.	Zhang X et al.	2014	PloS one
25741868	Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.	Richards S et al.	2015	Genetics in medicine
26695147	PTEN polymorphisms contribute to clinical outcomes of advanced lung adenocarcinoma patients treated with platinum-based chemotherapy.	Yang Y et al.	2016	Tumour biology
33082400	MLH1 single-nucleotide variant in circulating tumor DNA predicts overall survival of patients with hepatocellular carcinoma.	Kim SS et al.	2020	Scientific reports

The Flanks tab provides retrieving flanking sequences of a SNP on all molecules that have placements.

Genome context:

Select flank length:

Genomic regions, transcripts, and products
Top▲ Help
NCBI Graphical Sequence Viewer display of the genomic region, transcripts and protein products for the reported RefSNP (rs).
Use the zoom option to view the nucleotides around the RefSNP and find other neighboring RefSNPs.
Visit Sequence Viewer for help with navigating inside the display and modifying the selection of displayed data tracks.

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dbSNP Short Genetic Variations

Welcome to the Reference SNP (rs) Report

Reference SNP (rs) Report

rs11202592