| COG0042 |
J
|
DusA
|
tRNA-dihydrouridine synthase |
EC 1.3.1.91 |
| COG0324 |
J
|
MiaA
|
tRNA A37 N6-isopentenylltransferase MiaA |
EC 2.5.1.75 |
| COG0621 |
J
|
MiaB
|
tRNA A37 methylthiotransferase MiaB |
EC 2.8.4.3 |
| COG4445 |
J
|
MiaE
|
tRNA A37 isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE |
None |
| COG1214 |
J
|
TsaB
|
tRNA A37 threonylcarbamoyladenosine modification protein TsaB |
None |
| COG0009 |
J
|
TsaC
|
tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC |
EC 2.7.7.87 |
| COG0533 |
J
|
TsaD
|
tRNA A37 threonylcarbamoyltransferase TsaD |
EC 2.3.1.234 |
| COG0802 |
J
|
TsaE
|
tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE |
None |
| COG1179 |
J
|
TcdA
|
tRNA A37 threonylcarbamoyladenosine dehydratase |
None |
| COG3642 |
J
|
Bud32
|
tRNA A37 N6-threonylcarbamoyl transferase component Bud32 |
None |
| COG2892 |
J
|
Pcc1
|
tRNA A37 N6-threonylcarbamoyladenosine modification (KEOPS) complex, Pcc1 subunit |
None |
| COG1041 |
J
|
Trm11
|
tRNA G10 N-methylase Trm11 |
EC 2.1.1.214 |
| COG0220 |
J
|
TrmB
|
tRNA G46 N7-methylase TrmB |
EC 2.1.1.33 |
| COG0336 |
J
|
TrmD
|
tRNA G37 N-methylase TrmD |
EC 2.1.1.228 |
| COG0482 |
J
|
MnmA
|
tRNA U34 2-thiouridine synthase MnmA/TrmU, contains the PP-loop ATPase domain |
EC 2.8.1.13 |
| COG4121 |
J
|
MnmC
|
tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC |
EC 2.1.1.61 |
| COG0486 |
J
|
MnmE
|
tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE |
None |
| COG0445 |
J
|
MnmG
|
tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA |
None |
| COG0617 |
J
|
PcnB
|
tRNA nucleotidyltransferase (CCA-adding enzyme)/poly(A) polymerase |
EC 2.7.7.72 |
| COG0809 |
J
|
QueA
|
S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) |
EC 2.4.99.17 |
| COG0603 |
J
|
QueC
|
7-cyano-7-deazaguanine synthase (queuosine biosynthesis) |
EC 6.3.4.20 |
| COG0720 |
H
|
QueD
|
6-pyruvoyl-tetrahydropterin synthase |
EC 4.1.2.50 |
| COG0602 |
H
|
QueE
|
Organic radical activating enzyme, includes 7-carboxy-7-deazaguanine synthase NrdG/QueE |
EC:4.3.99.3 |
| COG0780 |
J
|
QueFC
|
NADPH-dependent 7-cyano-7-deazaguanine reductase QueF, C-terminal domain, T-fold superfamily |
EC 1.7.1.13 |
| COG1600 |
J
|
QueG
|
Epoxyqueuosine reductase QueG (queuosine biosynthesis) |
EC 1.17.99.6 |
| COG1746 |
J
|
CCA1
|
tRNA nucleotidyltransferase (archaeal CCA-adding enzyme) |
EC 2.7.7.72 |
| COG1617 |
J
|
Cgi121
|
tRNA threonylcarbamoyladenosine modification (KEOPS) complex, Cgi121 subunit |
None |
| COG2519 |
J
|
Gcd14
|
tRNA A57/A58 N1-methylase Trm61 |
EC 2.1.1.220 |
| COG1258 |
J
|
Pus10
|
tRNA U54 and U55 pseudouridine synthase Pus10 |
EC 5.4.99.25 |
| COG1676 |
J
|
SEN2
|
tRNA splicing endonuclease subunit SEN34 |
EC 4.6.1.16 |
| COG2603 |
J
|
SelU
|
tRNA U34 2-selenouridine synthase SelU, contains rhodanese domain |
EC 2.5.1.- |
| COG0566 |
J
|
SpoU
|
tRNA G18 (ribose-2'-O)-methylase SpoU |
EC 2.1.1.34 |
| COG0590 |
J
|
TadA
|
tRNA(Arg) A34 adenosine deaminase TadA |
EC 3.5.4.33 |
| COG1818 |
J
|
Tan1
|
tRNA(Ser,Leu) C12 N-acetylase TAN1, contains THUMP domain |
None |
| COG1187 |
J
|
RluF
|
Pseudouridylate synthase RsuA/RluF, specific for 16S rRNA U516, 23S rRNA U2604/U2605/U2457, and tRNA(Tyr)-35 |
None |
| COG0343 |
J
|
Tgt
|
Queuine/archaeosine tRNA-ribosyltransferase |
EC 2.4.2.29 |
| COG4021 |
J
|
Thg1
|
tRNA(His) 5'-end guanylyltransferase/3'-5' nucleotidyltransferase |
EC 2.7.7.79 |
| COG1571 |
J
|
TiaS
|
tRNA(Ile2) C34 agmatinyltransferase TiaS |
EC 6.3.4.22 |
| COG0037 |
J
|
TilS
|
tRNA-C32 2-thiocytidine or tRNA(Ile)-C34 C2-lysylcytidine synthase TtcA/TilS/MesJ |
EC 6.3.4.19;EC 2.8.1.- |
| COG1444 |
J
|
TmcA
|
tRNA(Met) C34 N-acetyltransferase TmcA |
EC 2.3.1.193 |
| COG1323 |
J
|
TmcAL
|
tRNA-Met C34-N4-acetylcytidine synthase TmcAL |
EC 6.3.4.- |
| COG5324 |
J
|
Trl1
|
tRNA splicing ligase |
None |
| COG0144 |
J
|
Trm4
|
RNA cytosine C5-methylase, RsmB/RsmF/Trm4/Trm9 family, includes 16S rRNA C967/C1407 and tRNA-C34/C48 C5-methylases |
EC:2.1.1.229;EC 2.1.1.- |
| COG2520 |
J
|
Trm5
|
tRNA G37 N1-methylase Trm5 |
EC 2.1.1.228 |
| COG0293 |
J
|
Trm7
|
23S rRNA U2552 or 16S rRNA-U1369 or eukaryotic tRNA-C32/G34 (ribose-2'-O)-methylase RlmE/FtsJ/TRM7 |
EC 2.1.1.205 |
| COG2265 |
J
|
TrmA
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family |
EC 2.1.1.35;EC 2.1.1.189;EC 2.1.1.190 |
| COG1206 |
J
|
TrmFO
|
Folate-dependent tRNA-U54 methylase TrmFO/GidA |
EC 2.1.1.74 |
| COG0565 |
J
|
TrmJ
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase |
EC 2.1.1.200 |
| COG0270 |
J
,
L
|
Dcm
|
DNA-cytosine methylase Dcm or eukaryotic tRNA-C38 C5-methylase, Dcm/DNMT2/TRDMT1 family |
EC 2.1.1.204 |
| COG0500 |
Q
,
R
|
CmoB
|
SAM-dependent methyltransferase SmtA (CmoB moved to COG2228) |
EC 2.5.1.- |
| COG2227 |
H
|
CmoM
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase |
EC:2.1.1.- |
| COG1187 |
J
|
TapT
|
Pseudouridylate synthase RsuA/RluF, specific for 16S rRNA U516, 23S rRNA U2604/U2605/U2457, and tRNA(Tyr)-35 |
EC:2.5.1.25 |
| COG2384 |
J
|
TrmK
|
tRNA A22 N1-methylase |
EC 2.1.1.217 |
| COG0219 |
J
|
TrmL
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain |
EC 2.1.1.207 |
| COG4123 |
J
|
TrmN6
|
tRNA1(Val) A37 N6-methylase TrmN6 |
EC 2.1.1.223 |
| COG1720 |
J
|
TrmO
|
tRNA (Thr-GGU) A37 N6-methylase |
EC 2.1.1.- |
| COG4122 |
J
|
TrmR
|
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM |
EC 2.1.1.- |
| COG1901 |
J
|
TrmY
|
tRNA pseudouridine-54 N-methylase |
EC 2.1.1.257 |
| COG1867 |
J
|
Trm1
|
tRNA G26 N,N-dimethylase Trm1 |
EC 2.1.1.216 |
| COG2419 |
J
|
Trm10
|
tRNA (A,G)9-N1-methylase TRM10 |
EC 2.1.1.218 |
| COG0116 |
J
|
Trm14
|
RNA guanine methylase, includes 23S rRNA G2445 N2-methylase RlmL and tRNA-G6 N2-methylase Trm14 |
EC 2.1.1.256 |
| COG0101 |
J
|
TruA
|
tRNA U38,U39,U40 pseudouridine synthase TruA |
EC 5.4.99.12 |
| COG0130 |
J
|
TruB
|
tRNA U55 pseudouridine synthase TruB, may also work on U342 of tmRNA |
EC 5.4.99.25 |
| COG0585 |
J
|
TruD
|
tRNA(Glu) U13 pseudouridine synthase TruD |
EC 5.4.99.27 |
| COG0731 |
J
|
Tyw1
|
Wyosine [tRNA(Phe)-imidazoG37] synthetase, radical SAM superfamily |
EC 4.1.3.44 |
| COG1590 |
J
|
Tyw3
|
tRNA(Phe) wybutosine-synthesizing methylase Tyw3 |
EC 2.1.1.282 |
| COG2117 |
J
|
|
Adenosine-binding enzyme, AANH-like superfamily |
None |
