F - Nucleotide transport and metabolism
Stats
| COG definitions |
Organims | Proteins | Median Protein Length |
Genes |
|---|---|---|---|---|
| 133 | 2,296 | 181,529 | 294.0 | 123 |
| Organism | Protein | COG | Cat | Annotation |
|---|---|---|---|---|
| 1623 | 2050 | COG0005 | F | Purine nucleoside phosphorylase |
| 2137 | 2588 | COG0015 | F | Adenylosuccinate lyase |
| 1565 | 1600 | COG0026 | F | Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) |
| 502 | 508 | COG0027 | F | Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) |
| 2059 | 2195 | COG0034 | F | Glutamine phosphoribosylpyrophosphate amidotransferase |
| 1669 | 1733 | COG0035 | F | Uracil phosphoribosyltransferase |
| 2066 | 2107 | COG0041 | F | Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase |
| 1962 | 3539 | COG0044 | F | Dihydroorotase or related cyclic amidohydrolase |
| 2043 | 2059 | COG0046 | F | Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain |
| 2049 | 2053 | COG0047 | F | Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain |
| 1825 | 1854 | COG0062 | F | NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate epimerase (NAXE) domain |
| 1999 | 2106 | COG0063 | F | NAD(P)H-hydrate repair enzyme Nnr, NAD(P)H-hydrate dehydratase (NAXD) domain |
| 1305 | 1976 | COG0075 | E F | Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG |
| 2117 | 2217 | COG0104 | F | Adenylosuccinate synthase |
| 1996 | 2040 | COG0105 | F | Nucleoside diphosphate kinase |
| 2041 | 2400 | COG0125 | F | Thymidylate kinase |
| 2180 | 2291 | COG0127 | F | Inosine/xanthosine triphosphate pyrophosphatase, all-alpha NTP-PPase family |
| 2025 | 2177 | COG0138 | F | AICAR transformylase/IMP cyclohydrolase PurH |
| 2057 | 2067 | COG0150 | F | Phosphoribosylaminoimidazole (AIR) synthetase |
| 2053 | 2142 | COG0151 | F | Phosphoribosylamine-glycine ligase |
| 2069 | 2176 | COG0152 | F | Phosphoribosylaminoimidazole-succinocarboxamide synthase |
| 2150 | 2935 | COG0167 | F | Dihydroorotate dehydrogenase |
| 2026 | 2161 | COG0194 | F | Guanylate kinase |
| 1492 | 1557 | COG0207 | F | Thymidylate synthase |
| 1415 | 1670 | COG0208 | F | Ribonucleotide reductase beta subunit, ferritin-like domain |
| 2047 | 2822 | COG0209 | F | Ribonucleotide reductase alpha subunit |
| 1145 | 1221 | COG0213 | F | Thymidine phosphorylase |
| 1488 | 1692 | COG0232 | F | dGTP triphosphohydrolase |
| 1667 | 2480 | COG0248 | T F | Exopolyphosphatase/pppGpp-phosphohydrolase |
| 1430 | 1692 | COG0274 | F | Deoxyribose-phosphate aldolase |
| 1989 | 2000 | COG0283 | F | Cytidylate kinase |
| 2131 | 2197 | COG0284 | F | Orotidine-5'-phosphate decarboxylase |
| 1369 | 1514 | COG0295 | F | Cytidine deaminase |
| 1934 | 1977 | COG0299 | F | Folate-dependent phosphoribosylglycinamide formyltransferase PurN |
| 628 | 812 | COG0369 | F P | Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases |
| 1624 | 4467 | COG0402 | F R | Cytosine/adenosine deaminase or related metal-dependent hydrolase |
| 613 | 617 | COG0418 | F | Dihydroorotase |
| 2042 | 2719 | COG0458 | E F | Carbamoylphosphate synthase large subunit |
| 2141 | 2309 | COG0461 | F | Orotate phosphoribosyltransferase |
| 2205 | 2703 | COG0462 | E F | Phosphoribosylpyrophosphate synthetase |
| 1809 | 2778 | COG0503 | F | Adenine/guanine phosphoribosyltransferase or related PRPP-binding protein |
| 2168 | 2262 | COG0504 | F | CTP synthase (UTP-ammonia lyase) |
| 2021 | 2150 | COG0505 | E F | Carbamoylphosphate synthase small subunit |
| 2092 | 2802 | COG0516 | F | IMP dehydrogenase/GMP reductase |
| 2156 | 3659 | COG0518 | F | GMP synthase, glutamine amidotransferase domain/subunit |
| 2145 | 2209 | COG0519 | F | GMP synthase, PP-ATPase domain/subunit |
| 2213 | 2286 | COG0528 | F | Uridylate kinase |
| 2239 | 4083 | COG0537 | F R | Purine nucleoside phosphoramidase/Ap4A hydrolase, histidine triade (HIT) family |
| 2056 | 2118 | COG0540 | F | Aspartate carbamoyltransferase, catalytic subunit |
| 2188 | 3055 | COG0563 | F | Adenylate kinase or related kinase |
| 1151 | 1622 | COG0572 | F | Uridine kinase |
| 1453 | 2366 | COG0613 | A F | 5'-3' exoribonuclease/diribonuclease TrpH/YciV (RNase AM), contains PHP domain |
| 1622 | 1737 | COG0634 | F | Hypoxanthine-guanine phosphoribosyltransferase |
| 1104 | 1591 | COG0647 | F | Ribonucleotide monophosphatase NagD, HAD superfamily |
| 1488 | 1667 | COG0717 | F | dCTP deaminase |
| 1385 | 2701 | COG0737 | V F | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family |
| 1663 | 1719 | COG0756 | V F | dUTP pyrophosphatase (dUTPase) |
| 1367 | 1924 | COG0775 | F H | Nucleoside phosphorylase/nucleosidase, includes 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase MtnN and futalosine hydrolase MqnB |
| 1110 | 1277 | COG0788 | F | Formyltetrahydrofolate hydrolase |
| 629 | 678 | COG0813 | F | Purine-nucleoside phosphorylase |
| 96 | 101 | COG0856 | F | Orotate phosphoribosyltransferase homolog |
| 721 | 943 | COG1001 | F | Adenine/N6-methyladenosine deaminase |
| 2131 | 9222 | COG1051 | F | ADP-ribose pyrophosphatase YjhB, NUDIX family |
| 993 | 1708 | COG1079 | F | ABC-type guanosine uptake system NupNOPQ, permease subunit NupQ |
| 483 | 724 | COG1102 | F | Cytidylate kinase |
| 1097 | 1626 | COG1146 | F | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit |
| 1160 | 1178 | COG1286 | M F | Colicin V production accessory protein CvpA, regulator of purF expression and biofilm formation |
| 1020 | 1293 | COG1328 | F | Anaerobic ribonucleoside-triphosphate reductase |
| 805 | 825 | COG1351 | F | Thymidylate synthase ThyX, FAD-dependent family |
| 537 | 799 | COG1428 | F | Deoxyadenosine/deoxycytidine kinase |
| 1108 | 1133 | COG1435 | F | Thymidine kinase |
| 736 | 1194 | COG1457 | F | Purine-cytosine permease or related protein |
| 1609 | 1642 | COG1496 | M F | UDP-MurNAc-monopeptide hydrolase/purine nucleoside phosphorylase YfiH, contains laccase domain |
| 1791 | 2885 | COG1611 | F | Nucleotide monophosphate nucleosidase PpnN/YdgH, Lonely Guy (LOG) family |
| 197 | 208 | COG1618 | F | Nucleoside-triphosphatase THEP1 |
| 607 | 745 | COG1683 | F | 2-thiouracil desulfurase TudS/YbbK, DUF523 family |
| 598 | 619 | COG1691 | F | NCAIR mutase (PurE)-related protein |
| 82 | 151 | COG1759 | F | 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase (purine biosynthesis) |
| 317 | 349 | COG1780 | F | Flavodoxin NrdI, NrdF-interacting activator of class Ib ribonucleotide reductase |
| 449 | 450 | COG1781 | F | Aspartate carbamoyltransferase, regulatory subunit |
| 939 | 1360 | COG1816 | F | Adenosine/6-amino-6-deoxyfutalosine deaminase |
| 1117 | 1118 | COG1828 | F | Phosphoribosylformylglycinamidine (FGAM) synthase, PurS subunit |
| 165 | 165 | COG1839 | F | Adenosine/AMP kinase |
| 130 | 131 | COG1860 | L F | Predicted metal-binding protein, contains two cysteine clusters, UPF0179 family |
| 426 | 534 | COG1864 | F | DNA/RNA endonuclease G, NUC1 |
| 896 | 1152 | COG1896 | F R | 5'-deoxynucleotidase YfbR and related HD superfamily hydrolases |
| 242 | 250 | COG1936 | F | Broad-specificity NMP kinase |
| 329 | 430 | COG1953 | F H | Cytosine/uracil/thiamine/allantoin permease |
| 926 | 1605 | COG1957 | F | Inosine-uridine nucleoside N-ribohydrolase |
| 655 | 864 | COG1972 | F | Nucleoside permease NupC |
| 308 | 318 | COG1986 | V F | Non-canonical (house-cleaning) NTP pyrophosphatase, all-alpha NTP-PPase family |
| 114 | 123 | COG2019 | F | Archaeal adenylate kinase |
| 1116 | 1275 | COG2065 | F | Pyrimidine operon attenuation protein PyrR/uracil phosphoribosyltransferase |
| 933 | 969 | COG2131 | J F | dCMP deaminase ComEB or tRNA-C8 deaminase CDAT8 |
| 1143 | 2019 | COG2233 | F | Xanthine/uracil permease |
| 1207 | 1711 | COG2252 | F | Xanthine/guanine/uracil/vitamin C permease GhxP/GhxQ, nucleobase:cation symporter 2 ( NCS2) family |
| 1013 | 1328 | COG2258 | V F | N-hydroxylaminopurine reductase YiiM, contains MOSC domain |
| 122 | 151 | COG2306 | F | NTP/NDPase, contains DUF402 domain |
| 443 | 451 | COG2313 | F | Pseudouridine-5'-phosphate glycosidase (pseudoU degradation) |
| 589 | 651 | COG2351 | F | 5-hydroxyisourate hydrolase (purine catabolism), transthyretin-related family |
| 543 | 759 | COG2357 | T F | ppGpp synthetase catalytic domain (RelA/SpoT-type nucleotidyltranferase) |
| 101 | 112 | COG2429 | F | Archaeal GTP cyclohydrolase III |
| 907 | 957 | COG2759 | F | Formyltetrahydrofolate synthetase |
| 1021 | 1155 | COG2816 | F | NADH pyrophosphatase NudC, Nudix superfamily |
| 681 | 931 | COG2820 | F | Uridine phosphorylase |
| 67 | 68 | COG3097 | F | N4-acylcytosine amidohydrolase YqfB, UPF0267 family |
| 380 | 390 | COG3123 | F | Pyrimidine/purine nucleoside phosphorylase YaiE/PpnP, UPF0345/DUF1255 family |
| 329 | 391 | COG3194 | F | Ureidoglycolate hydrolase (allantoin degradation) |
| 533 | 588 | COG3195 | F | 2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase (uric acid degradation) |
| 294 | 326 | COG3199 | F | NAD kinase |
| 734 | 829 | COG3217 | V F | N-hydroxylaminopurine reductase subunit YcbX, contains MOSC domain |
| 287 | 317 | COG3257 | F | Ureidoglycine aminohydrolase |
| 153 | 153 | COG3363 | F | Archaeal IMP cyclohydrolase |
| 222 | 232 | COG3557 | F | NTP/NDP phosphatase, UPF0374/DUF402 family |
| 307 | 351 | COG3613 | F | Nucleoside 2-deoxyribosyltransferase |
| 1094 | 2423 | COG3845 | F | ABC-type guanosine uptake system NupNOPQ, ATPase component NupO |
| 15 | 17 | COG4027 | F | 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase |
| 169 | 179 | COG4119 | F R | Predicted NTP pyrophosphohydrolase, NUDIX family |
| 153 | 173 | COG4266 | F | Allantoicase |
| 244 | 265 | COG4290 | F | Guanyl-specific ribonuclease Sa |
| 178 | 211 | COG4317 | F | Xanthosine utilization system component, XapX domain |
| 114 | 116 | COG4360 | F | ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) |
| 174 | 178 | COG4502 | F | 5'(3')-deoxyribonucleotidase |
| 140 | 155 | COG4508 | F | Dimeric dUTPase, all-alpha-NTP-PPase (MazG) superfamily |
| 996 | 1706 | COG4603 | F | ABC-type guanosine uptake system NupNOPQ, permease component NupP |
| 409 | 434 | COG4630 | F | Xanthine dehydrogenase, Fe-S cluster and FAD-binding subunit XdhA |
| 403 | 423 | COG4631 | F | Xanthine dehydrogenase, molybdopterin-binding subunit XdhB |
| 167 | 168 | COG4696 | F | NTP pyrophosphatase, MazG superfamily |
| 250 | 266 | COG4708 | J F | Membrane component QueT of the ECF-type transporter of queuosine precursor |
| 40 | 43 | COG4741 | F | Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase |
| 27 | 35 | COG4855 | F | Uncharacterized conserved protein, DUF2180 domain |
| 98 | 123 | COG5042 | F | Purine nucleoside permease |
| 8 | 9 | COG5371 | F | Nucleoside diphosphatase, GDA1/CD39 family |