From HPO
ACTH-producing pituitary gland adenoma- MedGen UID:
- 266291
- •Concept ID:
- C1306214
- •
- Neoplastic Process
A type of pituitary adenoma that produces adrenocorticotropic hormone (ACTH).
Pituitary growth hormone cell adenoma- MedGen UID:
- 866320
- •Concept ID:
- C4018860
- •
- Neoplastic Process
A type of pituitary adenoma that produces growth hormone.
Acral overgrowth- MedGen UID:
- 1789172
- •Concept ID:
- C1735881
- •
- Disease or Syndrome
Excessive growth of hands and feet (predominantly due to soft tissue swelling). Typical manifestations include shoe size increase, foot enlargement, glove tightness, and hand enlargement.
Increased circulating prolactin concentration- MedGen UID:
- 1702649
- •Concept ID:
- C5200994
- •
- Finding
The presence of abnormally increased levels of prolactin in the blood. Prolactin is a peptide hormone produced by the anterior pituitary gland that plays a role in breast development and lactation during pregnancy.
Hyperpigmentation of the skin- MedGen UID:
- 57992
- •Concept ID:
- C0162834
- •
- Pathologic Function
A darkening of the skin related to an increase in melanin production and deposition.
Elevated circulating growth hormone concentration- MedGen UID:
- 66732
- •Concept ID:
- C0235986
- •
- Finding
Acromegaly is a condition resulting from overproduction of growth hormone by the pituitary gland in persons with closed epiphyses, and consists chiefly in the enlargement of the distal parts of the body. The circumference of the skull increases, the nose becomes broad, the tongue becomes enlarged, the facial features become coarsened, the mandible grows excessively, and the teeth become separated. The fingers and toes grow chiefly in thickness.
Increased circulating ACTH level- MedGen UID:
- 867375
- •Concept ID:
- C4021740
- •
- Finding
An abnormal increased in the concentration of corticotropin, also known as adrenocorticotropic hormone (ACTH), in the blood.
Increased circulating cortisol level- MedGen UID:
- 871175
- •Concept ID:
- C4025651
- •
- Finding
Overproduction of the hormone of cortisol by the adrenal cortex, resulting in a characteristic combination of clinical symptoms termed Cushing syndrome, with truncal obesity, a round, full face, striae atrophicae and acne, muscle weakness, and other features.
- Abnormality of the endocrine system
- Abnormality of the integument
- Abnormality of the nervous system
- Growth abnormality
- Neoplasm