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Abnormal vena cava morphology

MedGen UID:
1391621
•Concept ID:
C4476886
•
Anatomical Abnormality
Synonym: Abnormality of the vena cava
 
HPO: HP:0005345

Definition

An abnormality of the structure of the veins that return deoxygenated blood from the body into the heart, i.e., the superior vena cava and the inferior vena cava. [from HPO]

Professional guidelines

PubMed

Unroofed coronary sinus syndrome: diagnosis, classification, and surgical treatment.
Ootaki Y, Yamaguchi M, Yoshimura N, Oka S, Yoshida M, Hasegawa T
J Thorac Cardiovasc Surg 2003 Nov;126(5):1655-6. doi: 10.1016/s0022-5223(03)01019-5. PMID: 14666054
Diagnosis and treatment of retrocaval ureter.
Zhang XD, Hou SK, Zhu JH, Wang XF, Meng GD, Qu XK
Eur Urol 1990;18(3):207-10. doi: 10.1159/000463911. PMID: 2261934
Dextrocardia: systematic approach to differential diagnosis.
Rao PS
Am Heart J 1981 Sep;102(3 Pt 1):389-403. doi: 10.1016/0002-8703(81)90315-x. PMID: 7023216

Recent clinical studies

Etiology

Diagnosis of fetal non-chromosomal abnormalities on routine ultrasound examination at 11-13 weeks' gestation.
Syngelaki A, Hammami A, Bower S, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2019 Oct;54(4):468-476. doi: 10.1002/uog.20844. PMID: 31408229
Safety, feasibility, tips and tricks of permanent pacemaker implantation in patients with isolated persistent left superior vena cava.
Sinha SK, Krishna V, Thakur R, Kumar A, Singh K, Jha MJ, Razi M, Mishra V, Asif M, Abdali N, Khanra D, Goel A, Pandey U, Varma CM
Minerva Cardioangiol 2017 Aug;65(4):446-449. doi: 10.23736/S0026-4725.16.04207-9. PMID: 28635248
Inferior vena cava filter-associated abnormalities: MDCT findings.
Rao B, Duran C, Steigner ML, Rybicki FJ
AJR Am J Roentgenol 2012 Jun;198(6):W605-10. doi: 10.2214/AJR.11.7664. PMID: 22623578
Cavopulmonary assist: (em)powering the univentricular fontan circulation.
Rodefeld MD, Frankel SH, Giridharan GA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2011;14(1):45-54. doi: 10.1053/j.pcsu.2011.01.015. PMID: 21444049Free PMC Article
"Right-sided" May-Thurner syndrome.
Abboud G, Midulla M, Lions C, El Ngheoui Z, Gengler L, Martinelli T, Beregi JP
Cardiovasc Intervent Radiol 2010 Oct;33(5):1056-9. Epub 2009 Jul 24 doi: 10.1007/s00270-009-9654-z. PMID: 19629587

Diagnosis

Identifying Anomalies of Systemic Venous Drainage: Systemic Venous Anomalies; Atrial Morphology.
Maddali MM, Al Kindi HN, Kandachar PS, Al Farqani A, Al Alawi KS, Al Kindi F, Al-Maskari SN, Spicer DE, Anderson RH
World J Pediatr Congenit Heart Surg 2023 Jul;14(4):490-496. Epub 2023 Mar 15 doi: 10.1177/21501351231158539. PMID: 36921325
The mysterious "double" arch.
Gopalakrishnan A, Sivasubramonian S, Valaparambil A
Echocardiography 2019 Feb;36(2):422-423. Epub 2019 Jan 9 doi: 10.1111/echo.14253. PMID: 30628131
Ectopic intracaval liver.
Rafiei P, Sebastian S, Patel RB, Roda MS
Clin Imaging 2012 Nov-Dec;36(6):869-72. Epub 2012 Jun 8 doi: 10.1016/j.clinimag.2012.01.005. PMID: 23154027
Recognition of persistent left superior vena cava in non-congenital patients undergoing cardiac surgery.
Lentini S, Recupero A
Perfusion 2011 Jul;26(4):347-50. Epub 2011 May 10 doi: 10.1177/0267659111408378. PMID: 21558302
Coronary artery fistulae.
Luo L, Kebede S, Wu S, Stouffer GA
Am J Med Sci 2006 Aug;332(2):79-84. doi: 10.1097/00000441-200608000-00005. PMID: 16909054

Therapy

Hepatocellular Carcinoma Extending into the Inferior Vena Cava and Right Atrium.
Kajihara Y
Balkan Med J 2021 Jul;38(4):249-250. doi: 10.5152/balkanmedj.2021.21590. PMID: 34274915Free PMC Article
Acquired systemic-to-pulmonary shunts in a 6-month-old child: case report and review of the literature.
Werner O, Ovaert C, Amedro P
Cardiol Young 2020 Mar;30(3):427-430. Epub 2020 Feb 10 doi: 10.1017/S1047951119003354. PMID: 32036804
Inferior vena cava filter-associated abnormalities: MDCT findings.
Rao B, Duran C, Steigner ML, Rybicki FJ
AJR Am J Roentgenol 2012 Jun;198(6):W605-10. doi: 10.2214/AJR.11.7664. PMID: 22623578
Vena cava filters: current concepts and controversies for the surgeon.
Martin MJ, Blair KS, Curry TK, Singh N
Curr Probl Surg 2010 Jul;47(7):524-618. doi: 10.1067/j.cpsurg.2010.03.004. PMID: 20682152
Neonatal thrombosis.
Clark RA
Neonatal Netw 2004 May-Jun;23(3):57-68. doi: 10.1891/0730-0832.23.3.57. PMID: 15182121

Prognosis

Elderly Man With Sudden Onset Back Pain.
Singh B, Goyal A, Dhanota DS, Ralhan S, Saggar K, Mohan B, Wander GS
Ann Emerg Med 2022 Jan;79(1):e3-e4. doi: 10.1016/j.annemergmed.2021.07.112. PMID: 34949419
Persistent left superior vena cava: Two case reports and a review from nephrologists' perspective.
Sahutoglu T, Sakaci T, Kara E, Ahbap E, Basturk T, Koc Y, Sevinc M, Akgol C, Kayarlar AO, Ucar ZA, Caglayan FB, Hasbal NB, Nazif P, Isleem M, Sahutoglu E, Unsal A
Hemodial Int 2016 Jul;20(3):369-77. Epub 2016 Feb 3 doi: 10.1111/hdi.12389. PMID: 26843030
Cavopulmonary assist: (em)powering the univentricular fontan circulation.
Rodefeld MD, Frankel SH, Giridharan GA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2011;14(1):45-54. doi: 10.1053/j.pcsu.2011.01.015. PMID: 21444049Free PMC Article
"Right-sided" May-Thurner syndrome.
Abboud G, Midulla M, Lions C, El Ngheoui Z, Gengler L, Martinelli T, Beregi JP
Cardiovasc Intervent Radiol 2010 Oct;33(5):1056-9. Epub 2009 Jul 24 doi: 10.1007/s00270-009-9654-z. PMID: 19629587
Coronary artery fistulae.
Luo L, Kebede S, Wu S, Stouffer GA
Am J Med Sci 2006 Aug;332(2):79-84. doi: 10.1097/00000441-200608000-00005. PMID: 16909054

Clinical prediction guides

Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Persistent left superior vena cava: Two case reports and a review from nephrologists' perspective.
Sahutoglu T, Sakaci T, Kara E, Ahbap E, Basturk T, Koc Y, Sevinc M, Akgol C, Kayarlar AO, Ucar ZA, Caglayan FB, Hasbal NB, Nazif P, Isleem M, Sahutoglu E, Unsal A
Hemodial Int 2016 Jul;20(3):369-77. Epub 2016 Feb 3 doi: 10.1111/hdi.12389. PMID: 26843030
Transvenous hepatic biopsy in stable Fontan patients undergoing cardiac catheterization.
Evans WN, Winn BJ, Yumiaco NS, Galindo A, Rothman A, Acherman RJ, Restrepo H
Pediatr Cardiol 2014 Oct;35(7):1273-8. Epub 2014 May 10 doi: 10.1007/s00246-014-0928-0. PMID: 24817681
May-Thurner syndrome: diagnosis and management.
Brazeau NF, Harvey HB, Pinto EG, Deipolyi A, Hesketh RL, Oklu R
Vasa 2013 Mar;42(2):96-105. doi: 10.1024/0301-1526/a000252. PMID: 23485836
Giant coronary sinus.
Nathani S, Parakh N, Chaturvedi V, Tyagi S
Tex Heart Inst J 2011;38(3):310-1. PMID: 21720482Free PMC Article

Recent systematic reviews

Deep venous thrombosis in patients with atresia of the inferior vena cava and right kidney hypoplasia (KILT syndrome): Systematic review of the literature.
Pantic N, Cvetkovic M, Milin-Lazovic J, Vukmirovic J, Pavlovic A, Virijevic M, Pravdic Z, Kozarac S, Sabljic N, Suvajdzic-Vukovic N, Dragas M, Mitrovic M
Vasc Med 2024 Jun;29(3):320-327. Epub 2024 Apr 4 doi: 10.1177/1358863X241240427. PMID: 38573108
Systematic review of electrophysiology procedures in patients with obstruction of the inferior vena cava.
Al-Sinan A, Chan KH, Young GD, Martin A, Sepahpour A, Sy RW
J Cardiovasc Electrophysiol 2022 Jun;33(6):1300-1311. Epub 2022 Apr 30 doi: 10.1111/jce.15505. PMID: 35441755Free PMC Article
Duplication and transposition of inferior vena cava: A meta-analysis of prevalence.
Hostiuc S, Minoiu C, Negoi I, Rusu MC, Hostiuc M
J Vasc Surg Venous Lymphat Disord 2019 Sep;7(5):742-755. Epub 2019 May 5 doi: 10.1016/j.jvsv.2019.01.063. PMID: 31068277
Is supine exercise associated with adverse maternal and fetal outcomes? A systematic review.
Mottola MF, Nagpal TS, Bgeginski R, Davenport MH, Poitras VJ, Gray CE, Davies GA, Adamo KB, Slater LG, Barrowman N, Barakat R, Ruchat SM
Br J Sports Med 2019 Jan;53(2):82-89. Epub 2018 Oct 18 doi: 10.1136/bjsports-2018-099919. PMID: 30337348
Left-sided and duplicate inferior vena cava: a case series and review.
Ang WC, Doyle T, Stringer MD
Clin Anat 2013 Nov;26(8):990-1001. Epub 2012 May 10 doi: 10.1002/ca.22090. PMID: 22576868

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