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Abnormal intrahepatic bile duct morphology

MedGen UID:
869157
•Concept ID:
C4023577
•
Anatomical Abnormality
Synonym: Abnormality of the intrahepatic bile duct
 
HPO: HP:0011040

Definition

An abnormality of the intrahepatic bile duct. [from HPO]

Professional guidelines

PubMed

Associations between ultrasound screening findings and cholangiocarcinoma diagnosis in an at-risk population.
Thinkhamrop K, Khuntikeo N, Chamadol N, Suwannatrai AT, Phimha S, Kelly M
Sci Rep 2022 Aug 6;12(1):13513. doi: 10.1038/s41598-022-17794-9. PMID: 35933509Free PMC Article
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma.
Aoki S, Inoue K, Klein S, Halvorsen S, Chen J, Matsui A, Nikmaneshi MR, Kitahara S, Hato T, Chen X, Kawakubo K, Nia HT, Chen I, Schanne DH, Mamessier E, Shigeta K, Kikuchi H, Ramjiawan RR, Schmidt TC, Iwasaki M, Yau T, Hong TS, Quaas A, Plum PS, Dima S, Popescu I, Bardeesy N, Munn LL, Borad MJ, Sassi S, Jain RK, Zhu AX, Duda DG
Gut 2022 Jan;71(1):185-193. Epub 2021 Jan 11 doi: 10.1136/gutjnl-2020-322493. PMID: 33431577Free PMC Article
Biliary atresia: new concepts of management.
Hays DM, Kimura K
Curr Probl Surg 1981 Sep;18(9):541-608. doi: 10.1016/s0011-3840(81)80016-0. PMID: 7026179

Recent clinical studies

Etiology

MicroRNAs and benign biliary tract diseases.
Gradilone SA, O'Hara SP, Masyuk TV, Pisarello MJ, LaRusso NF
Semin Liver Dis 2015 Feb;35(1):26-35. Epub 2015 Jan 29 doi: 10.1055/s-0034-1397346. PMID: 25632932Free PMC Article
Imaging features of ductal plate malformations in adults.
Venkatanarasimha N, Thomas R, Armstrong EM, Shirley JF, Fox BM, Jackson SA
Clin Radiol 2011 Nov;66(11):1086-93. Epub 2011 Aug 15 doi: 10.1016/j.crad.2011.05.008. PMID: 21840516
Genetic and molecular abnormalities in cholangiocarcinogenesis.
Hassid VJ, Orlando FA, Awad ZT, Tan D, Khoury T, Ahmed BH, Alrawi SJ
Anticancer Res 2009 Apr;29(4):1151-6. doi: 10.21873/anticanres.16345. PMID: 19414358Free PMC Article
Role of epigenetic alterations in cholangiocarcinoma.
Tischoff I, Wittekind C, Tannapfel A
J Hepatobiliary Pancreat Surg 2006;13(4):274-9. doi: 10.1007/s00534-005-1055-3. PMID: 16858537
Sweet's syndrome: clinicopathologic study of eleven cases.
Chan HL, Lee YS, Kuo TT
Int J Dermatol 1994 Jun;33(6):425-32. doi: 10.1111/j.1365-4362.1994.tb04045.x. PMID: 8056477

Diagnosis

Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Recent advances in the pathogenesis and management of biliary atresia.
Zagory JA, Nguyen MV, Wang KS
Curr Opin Pediatr 2015 Jun;27(3):389-94. doi: 10.1097/MOP.0000000000000214. PMID: 25944310Free PMC Article
Alagille syndrome: an overview.
Vajro P, Ferrante L, Paolella G
Clin Res Hepatol Gastroenterol 2012 Jun;36(3):275-7. Epub 2012 Apr 18 doi: 10.1016/j.clinre.2012.03.019. PMID: 22521120
Biliary cystadenoma.
Hernandez Bartolome MA, Fuerte Ruiz S, Manzanedo Romero I, Ramos Lojo B, Rodriguez Prieto I, Gimenez Alvira L, Granados Carreño R, Limones Esteban M
World J Gastroenterol 2009 Jul 28;15(28):3573-5. doi: 10.3748/wjg.15.3573. PMID: 19630118Free PMC Article
Intrahepatic cholestasis.
Balistreri WF
J Pediatr Gastroenterol Nutr 2002;35 Suppl 1:S17-23. doi: 10.1097/00005176-200207001-00006. PMID: 12151816

Therapy

Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinoma.
DiPeri TP, Zhao M, Evans KW, Varadarajan K, Moss T, Scott S, Kahle MP, Byrnes CC, Chen H, Lee SS, Halim AB, Hirai H, Wacheck V, Kwong LN, Rodon J, Javle M, Meric-Bernstam F
J Hepatol 2024 Feb;80(2):322-334. Epub 2023 Nov 14 doi: 10.1016/j.jhep.2023.10.041. PMID: 37972659
IgG4-related disease coexisting with autoimmune haemolytic anaemia.
Wang KC, Liao HT, Tsai CY
BMJ Case Rep 2018 Jul 6;2018 doi: 10.1136/bcr-2018-224814. PMID: 29982182Free PMC Article
Portal biliopathy.
Khuroo MS, Rather AA, Khuroo NS, Khuroo MS
World J Gastroenterol 2016 Sep 21;22(35):7973-82. doi: 10.3748/wjg.v22.i35.7973. PMID: 27672292Free PMC Article
Minocycline-induced liver injury.
Malcolm A, Heap TR, Eckstein RP, Lunzer MR
Am J Gastroenterol 1996 Aug;91(8):1641-3. PMID: 8759678
Severe familial intrahepatic cholestasis.
Odiévre M, Gautier M, Hadchouel M, Alagille D
Arch Dis Child 1973 Oct;48(10):806-12. doi: 10.1136/adc.48.10.806. PMID: 4749685Free PMC Article

Prognosis

Recent advances in the pathogenesis and management of biliary atresia.
Zagory JA, Nguyen MV, Wang KS
Curr Opin Pediatr 2015 Jun;27(3):389-94. doi: 10.1097/MOP.0000000000000214. PMID: 25944310Free PMC Article
MicroRNAs and benign biliary tract diseases.
Gradilone SA, O'Hara SP, Masyuk TV, Pisarello MJ, LaRusso NF
Semin Liver Dis 2015 Feb;35(1):26-35. Epub 2015 Jan 29 doi: 10.1055/s-0034-1397346. PMID: 25632932Free PMC Article
Genetic and molecular abnormalities in cholangiocarcinogenesis.
Hassid VJ, Orlando FA, Awad ZT, Tan D, Khoury T, Ahmed BH, Alrawi SJ
Anticancer Res 2009 Apr;29(4):1151-6. doi: 10.21873/anticanres.16345. PMID: 19414358Free PMC Article
Surgery for biliary atresia.
Ohi R
Liver 2001 Jun;21(3):175-82. doi: 10.1034/j.1600-0676.2001.021003175.x. PMID: 11422780
Caroli's disease.
Mercadier M, Chigot JP, Clot JP, Langlois P, Lansiaux P
World J Surg 1984 Feb;8(1):22-9. doi: 10.1007/BF01658359. PMID: 6367232

Clinical prediction guides

Generation of human iPSC-derived 3D bile duct within liver organoid by incorporating human iPSC-derived blood vessel.
Carolina E, Kuse Y, Okumura A, Aoshima K, Tadokoro T, Matsumoto S, Kanai E, Okumura T, Kasai T, Yamabe S, Nishikawa Y, Yamaguchi K, Furukawa Y, Tanimizu N, Taniguchi H
Nat Commun 2024 Aug 28;15(1):7424. doi: 10.1038/s41467-024-51487-3. PMID: 39198465Free PMC Article
Circular RNAs in cholangiocarcinoma.
Liao W, Feng Q, Liu H, Du J, Chen X, Zeng Y
Cancer Lett 2023 Jan 28;553:215980. Epub 2022 Nov 4 doi: 10.1016/j.canlet.2022.215980. PMID: 36336149
Anatomic variations of intrahepatic bile ducts in a European series and meta-analysis of the literature.
Cucchetti A, Peri E, Cescon M, Zanello M, Ercolani G, Zanfi C, Bertuzzo V, Di Gioia P, Pinna AD
J Gastrointest Surg 2011 Apr;15(4):623-30. Epub 2011 Feb 12 doi: 10.1007/s11605-011-1447-4. PMID: 21318444
Idiopathic adulthood ductopenia.
Nakano I, Fukuda Y, Koyama Y, Urano F, Yamada M, Katano Y, Marui A, Imada K, Hayakawa T, Ito M, Yamashita Y, Imoto M, Nakanuma Y
J Gastroenterol Hepatol 1996 Apr;11(4):411-5. doi: 10.1111/j.1440-1746.1996.tb01392.x. PMID: 8713711
del(20p) with manifestations of arteriohepatic dysplasia.
Byrne JL, Harrod MJ, Friedman JM, Howard-Peebles PN
Am J Med Genet 1986 Aug;24(4):673-8. doi: 10.1002/ajmg.1320240411. PMID: 3740100

Recent systematic reviews

Association of mucin family members with prognostic significance in pancreatic cancer patients: A meta-analysis.
Xu W, Zhang M, Liu L, Yin M, Xu C, Weng Z
PLoS One 2022;17(6):e0269612. Epub 2022 Jun 16 doi: 10.1371/journal.pone.0269612. PMID: 35709153Free PMC Article
Risk of malignancy in Caroli disease and syndrome: A systematic review.
Fahrner R, Dennler SG, Inderbitzin D
World J Gastroenterol 2020 Aug 21;26(31):4718-4728. doi: 10.3748/wjg.v26.i31.4718. PMID: 32884228Free PMC Article
The role of imaging in determining prognosis for primary sclerosing cholangitis: A systematic review.
Segal D, Marotta P, Mosli M, Zou G, Feagan BG, Al-Judaibi B
Saudi J Gastroenterol 2019 May-Jun;25(3):152-158. doi: 10.4103/sjg.SJG_478_18. PMID: 31044745Free PMC Article
Meta-analysis of risk of developing malignancy in congenital choledochal malformation.
Ten Hove A, de Meijer VE, Hulscher JBF, de Kleine RHJ
Br J Surg 2018 Apr;105(5):482-490. Epub 2018 Feb 26 doi: 10.1002/bjs.10798. PMID: 29480528Free PMC Article
Therapeutic approaches for portal biliopathy: A systematic review.
Franceschet I, Zanetto A, Ferrarese A, Burra P, Senzolo M
World J Gastroenterol 2016 Dec 7;22(45):9909-9920. doi: 10.3748/wjg.v22.i45.9909. PMID: 28018098Free PMC Article

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