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Generalized opacification of the cornea

MedGen UID:
866795
Concept ID:
C4021147
Anatomical Abnormality
Synonym: Generalised opacification of the cornea
 
HPO: HP:0011494

Definition

Generalized reduced transparency of the stroma of the cornea. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Generalized opacification of the cornea

Professional guidelines

PubMed

Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177
Ramona BI, Catalina C, Andrei M, Daciana S, Calin T
Rom J Ophthalmol 2016 Jan-Mar;60(1):28-30. PMID: 27220229Free PMC Article
Amon M
Nepal J Ophthalmol 2011 Jan-Jun;3(1):3-8. doi: 10.3126/nepjoph.v3i1.4270. PMID: 21505539

Recent clinical studies

Etiology

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Chameettachal S, Venuganti A, Parekh Y, Prasad D, Joshi VP, Vashishtha A, Basu S, Singh V, Bokara KK, Pati F
Acta Biomater 2023 Nov;171:289-307. Epub 2023 Sep 7 doi: 10.1016/j.actbio.2023.09.002. PMID: 37683964
Salik I, Gupta A, Tara A, Zaidman G, Barst S
Paediatr Anaesth 2020 May;30(5):577-583. Epub 2020 Mar 16 doi: 10.1111/pan.13843. PMID: 32107814
Hossain P, Tourkmani AK, Kazakos D, Jones M, Anderson D; NHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists
Br J Ophthalmol 2018 Jan;102(1):26-30. Epub 2017 May 11 doi: 10.1136/bjophthalmol-2016-309870. PMID: 28495906
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Diagnosis

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Lin HY, Chan WC, Chen LJ, Lee YC, Yeh SI, Niu DM, Chiu PC, Tsai WH, Hwu WL, Chuang CK, Lin SP
Mol Genet Genomic Med 2019 May;7(5):e00617. Epub 2019 Mar 8 doi: 10.1002/mgg3.617. PMID: 30848093Free PMC Article
Hossain P, Tourkmani AK, Kazakos D, Jones M, Anderson D; NHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists
Br J Ophthalmol 2018 Jan;102(1):26-30. Epub 2017 May 11 doi: 10.1136/bjophthalmol-2016-309870. PMID: 28495906
Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177

Therapy

Riedl JC, Misirkhanova A, Wasielica-Poslednik J, Schuster AK, Schmidtmann I, Beutel ME, Pfeiffer N, Gericke A
Acta Ophthalmol 2024 Sep;102(6):e956-e960. Epub 2024 Mar 27 doi: 10.1111/aos.16680. PMID: 38536709
Kumar R, Sinha NR, Mohan RR
Ocul Surf 2023 Jul;29:279-297. Epub 2023 May 25 doi: 10.1016/j.jtos.2023.05.007. PMID: 37244594
Vrijman V, van der Linden JW, van der Meulen IJE, Mourits MP, Lapid-Gortzak R
J Cataract Refract Surg 2018 Apr;44(4):466-470. Epub 2018 Apr 22 doi: 10.1016/j.jcrs.2018.01.030. PMID: 29685778
Ramona BI, Catalina C, Andrei M, Daciana S, Calin T
Rom J Ophthalmol 2016 Jan-Mar;60(1):28-30. PMID: 27220229Free PMC Article
Casprini F, Balestrazzi A, Tosi GM, Miracco F, Martone G, Cevenini G, Caporossi A
Acta Ophthalmol Scand 2005 Feb;83(1):20-5. doi: 10.1111/j.1600-0420.2005.00378.x. PMID: 15715552

Prognosis

Braddock FL, Gardner JC, Bhattacharyya N, Sanchez-Pintado B, Costa M, Zarouchlioti C, Szabo A, Lišková P, Cheetham ME, Young RD, Thaung C, Davidson AE, Tuft SJ, Hardcastle AJ
Eur J Hum Genet 2024 Dec;32(12):1583-1589. Epub 2024 Aug 21 doi: 10.1038/s41431-024-01687-8. PMID: 39169229Free PMC Article
Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Hossain P, Tourkmani AK, Kazakos D, Jones M, Anderson D; NHS Blood and Transplant Ocular Tissue Advisory Group and Contributing Ophthalmologists
Br J Ophthalmol 2018 Jan;102(1):26-30. Epub 2017 May 11 doi: 10.1136/bjophthalmol-2016-309870. PMID: 28495906
Ramona BI, Catalina C, Andrei M, Daciana S, Calin T
Rom J Ophthalmol 2016 Jan-Mar;60(1):28-30. PMID: 27220229Free PMC Article
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Clinical prediction guides

Moustardas P, Abbasi M, Javidjam D, Asamoah CS, Schweitzer-Chaput A, Cisternino S, Bremond-Gignac D, Aberdam D, Lagali N
Ocul Surf 2024 Oct;34:225-234. Epub 2024 Aug 8 doi: 10.1016/j.jtos.2024.08.008. PMID: 39127390
Williams D, Chung DD, Hovakimyan A, Davtyan A, Glasgow BJ, Aldave AJ
Cornea 2023 Apr 1;42(4):464-469. Epub 2022 Dec 19 doi: 10.1097/ICO.0000000000003167. PMID: 36534610
Santos-Bueso E
Arch Soc Esp Oftalmol (Engl Ed) 2019 Oct;94(10):471-477. Epub 2019 Aug 1 doi: 10.1016/j.oftal.2019.06.006. PMID: 31378388
Kivelä T, Uusitalo M
Prog Retin Eye Res 1998 Jul;17(3):385-428. doi: 10.1016/s1350-9462(98)00001-9. PMID: 9695798
Krumeich JH, Daniel J, Knülle A
J Cataract Refract Surg 1998 Apr;24(4):456-63. doi: 10.1016/s0886-3350(98)80284-8. PMID: 9584238

Recent systematic reviews

Jawaheer L, Anijeet D, Ramaesh K
Surv Ophthalmol 2017 Jul-Aug;62(4):522-532. Epub 2016 Nov 14 doi: 10.1016/j.survophthal.2016.11.003. PMID: 27856177

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