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Pulmonary fibrosis, idiopathic, susceptibility to

MedGen UID:
865126
•Concept ID:
C4016689
•
Finding
Synonym: PULMONARY FIBROSIS, IDIOPATHIC, SUSCEPTIBILITY TO
 
OMIM®: 600770

Professional guidelines

PubMed

Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis.
Ghosh AJ, Moll M, Hobbs BD, Cardwell J, Saferali A, Castaldi PJ, Cho MH, Silverman EK, Yang IV, Hersh CP
Am J Respir Crit Care Med 2023 May 15;207(10):1401-1404. doi: 10.1164/rccm.202209-1835LE. PMID: 36952240Free PMC Article
Idiopathic pulmonary fibrosis: pathogenesis and management.
Sgalla G, Iovene B, Calvello M, Ori M, Varone F, Richeldi L
Respir Res 2018 Feb 22;19(1):32. doi: 10.1186/s12931-018-0730-2. PMID: 29471816Free PMC Article
Immunopathology, diagnosis, and management of hypersensitivity pneumonitis.
Selman M, Buendía-Roldán I
Semin Respir Crit Care Med 2012 Oct;33(5):543-54. Epub 2012 Sep 21 doi: 10.1055/s-0032-1325163. PMID: 23001807

Recent clinical studies

Etiology

Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.
Adegunsoye A, Kropski JA, Behr J, Blackwell TS, Corte TJ, Cottin V, Glanville AR, Glassberg MK, Griese M, Hunninghake GM, Johannson KA, Keane MP, Kim JS, Kolb M, Maher TM, Oldham JM, Podolanczuk AJ, Rosas IO, Martinez FJ, Noth I, Schwartz DA
Am J Respir Crit Care Med 2024 Aug 15;210(4):401-423. doi: 10.1164/rccm.202401-0238SO. PMID: 38573068Free PMC Article
Associations of combined phenotypic ageing and genetic risk with incidence of chronic respiratory diseases in the UK Biobank: a prospective cohort study.
Wang T, Duan W, Jia X, Huang X, Liu Y, Meng F, Ni C
Eur Respir J 2024 Feb;63(2) Epub 2024 Feb 22 doi: 10.1183/13993003.01720-2023. PMID: 38061785Free PMC Article
Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis.
Bueno M, Calyeca J, Rojas M, Mora AL
Redox Biol 2020 Jun;33:101509. Epub 2020 Mar 19 doi: 10.1016/j.redox.2020.101509. PMID: 32234292Free PMC Article
Idiopathic pulmonary fibrosis: pathogenesis and management.
Sgalla G, Iovene B, Calvello M, Ori M, Varone F, Richeldi L
Respir Res 2018 Feb 22;19(1):32. doi: 10.1186/s12931-018-0730-2. PMID: 29471816Free PMC Article
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006

Diagnosis

Telomere-mediated lung disease.
Alder JK, Armanios M
Physiol Rev 2022 Oct 1;102(4):1703-1720. Epub 2022 May 9 doi: 10.1152/physrev.00046.2021. PMID: 35532056Free PMC Article
Developmental pathways in the pathogenesis of lung fibrosis.
Chanda D, Otoupalova E, Smith SR, Volckaert T, De Langhe SP, Thannickal VJ
Mol Aspects Med 2019 Feb;65:56-69. Epub 2018 Aug 23 doi: 10.1016/j.mam.2018.08.004. PMID: 30130563Free PMC Article
Idiopathic pulmonary fibrosis: pathogenesis and management.
Sgalla G, Iovene B, Calvello M, Ori M, Varone F, Richeldi L
Respir Res 2018 Feb 22;19(1):32. doi: 10.1186/s12931-018-0730-2. PMID: 29471816Free PMC Article
Idiopathic pulmonary fibrosis.
Martinez FJ, Collard HR, Pardo A, Raghu G, Richeldi L, Selman M, Swigris JJ, Taniguchi H, Wells AU
Nat Rev Dis Primers 2017 Oct 20;3:17074. doi: 10.1038/nrdp.2017.74. PMID: 29052582
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006

Therapy

Rheumatoid arthritis and idiopathic pulmonary fibrosis: a bidirectional Mendelian randomisation study.
Leavy OC, Kawano-Dourado L, Stewart ID, Quint JK, Solomon JJ, Borie R, Crestani B, Wain LV, Jenkins G, Dieudé P, Minelli C
Thorax 2024 May 20;79(6):538-544. doi: 10.1136/thorax-2023-220856. PMID: 38649271Free PMC Article
Air pollutants, genetic susceptibility and risk of incident idiopathic pulmonary fibrosis.
Cui F, Sun Y, Xie J, Li D, Wu M, Song L, Hu Y, Tian Y
Eur Respir J 2023 Feb;61(2) Epub 2023 Feb 2 doi: 10.1183/13993003.00777-2022. PMID: 36137588
Idiopathic pulmonary fibrosis: pathogenesis and management.
Sgalla G, Iovene B, Calvello M, Ori M, Varone F, Richeldi L
Respir Res 2018 Feb 22;19(1):32. doi: 10.1186/s12931-018-0730-2. PMID: 29471816Free PMC Article
The Bleomycin Model of Pulmonary Fibrosis.
Liu T, De Los Santos FG, Phan SH
Methods Mol Biol 2017;1627:27-42. doi: 10.1007/978-1-4939-7113-8_2. PMID: 28836192
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006

Prognosis

Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.
Adegunsoye A, Kropski JA, Behr J, Blackwell TS, Corte TJ, Cottin V, Glanville AR, Glassberg MK, Griese M, Hunninghake GM, Johannson KA, Keane MP, Kim JS, Kolb M, Maher TM, Oldham JM, Podolanczuk AJ, Rosas IO, Martinez FJ, Noth I, Schwartz DA
Am J Respir Crit Care Med 2024 Aug 15;210(4):401-423. doi: 10.1164/rccm.202401-0238SO. PMID: 38573068Free PMC Article
Associations of combined phenotypic ageing and genetic risk with incidence of chronic respiratory diseases in the UK Biobank: a prospective cohort study.
Wang T, Duan W, Jia X, Huang X, Liu Y, Meng F, Ni C
Eur Respir J 2024 Feb;63(2) Epub 2024 Feb 22 doi: 10.1183/13993003.01720-2023. PMID: 38061785Free PMC Article
Telomere-mediated lung disease.
Alder JK, Armanios M
Physiol Rev 2022 Oct 1;102(4):1703-1720. Epub 2022 May 9 doi: 10.1152/physrev.00046.2021. PMID: 35532056Free PMC Article
Idiopathic pulmonary fibrosis: pathogenesis and management.
Sgalla G, Iovene B, Calvello M, Ori M, Varone F, Richeldi L
Respir Res 2018 Feb 22;19(1):32. doi: 10.1186/s12931-018-0730-2. PMID: 29471816Free PMC Article
Bronchiolitis: update 2001.
Schlesinger C, Koss MN
Curr Opin Pulm Med 2002 Mar;8(2):112-6. doi: 10.1097/00063198-200203000-00006. PMID: 11845006

Clinical prediction guides

Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.
Adegunsoye A, Kropski JA, Behr J, Blackwell TS, Corte TJ, Cottin V, Glanville AR, Glassberg MK, Griese M, Hunninghake GM, Johannson KA, Keane MP, Kim JS, Kolb M, Maher TM, Oldham JM, Podolanczuk AJ, Rosas IO, Martinez FJ, Noth I, Schwartz DA
Am J Respir Crit Care Med 2024 Aug 15;210(4):401-423. doi: 10.1164/rccm.202401-0238SO. PMID: 38573068Free PMC Article
Associations of combined phenotypic ageing and genetic risk with incidence of chronic respiratory diseases in the UK Biobank: a prospective cohort study.
Wang T, Duan W, Jia X, Huang X, Liu Y, Meng F, Ni C
Eur Respir J 2024 Feb;63(2) Epub 2024 Feb 22 doi: 10.1183/13993003.01720-2023. PMID: 38061785Free PMC Article
Sex and Gender Differences in Lung Disease.
Silveyra P, Fuentes N, Rodriguez Bauza DE
Adv Exp Med Biol 2021;1304:227-258. doi: 10.1007/978-3-030-68748-9_14. PMID: 34019273Free PMC Article
Dysbiosis, malnutrition and enhanced gut-lung axis contribute to age-related respiratory diseases.
Saint-Criq V, Lugo-Villarino G, Thomas M
Ageing Res Rev 2021 Mar;66:101235. Epub 2020 Dec 13 doi: 10.1016/j.arr.2020.101235. PMID: 33321253
Mechanisms of pulmonary fibrosis.
Thannickal VJ, Toews GB, White ES, Lynch JP 3rd, Martinez FJ
Annu Rev Med 2004;55:395-417. doi: 10.1146/annurev.med.55.091902.103810. PMID: 14746528

Recent systematic reviews

Common single nucleotide polymorphisms associated with idiopathic pulmonary fibrosis: a systematic review.
Dhooria S, Sharma R, Bal A, Sehgal IS, Kashyap D, Muthu V, Prasad KT, Agarwal R, Aggarwal AN
Eur Respir Rev 2024 Jul;33(173) Epub 2024 Sep 25 doi: 10.1183/16000617.0018-2024. PMID: 39322261Free PMC Article
Genetic liability of gut microbiota for idiopathic pulmonary fibrosis and lung function: a two-sample Mendelian randomization study.
Ren Y, Zhang Y, Cheng Y, Qin H, Zhao H
Front Cell Infect Microbiol 2024;14:1348685. Epub 2024 May 22 doi: 10.3389/fcimb.2024.1348685. PMID: 38841114Free PMC Article
Increased frequency of angiotensin converting enzyme D allele in Chinese Han patients with idiopathic pulmonary fibrosis: A systematic review and meta-analysis.
Wu X, Li W, Huang G, Luo Z, Chen Y
Medicine (Baltimore) 2022 Oct 7;101(40):e30942. doi: 10.1097/MD.0000000000030942. PMID: 36221416Free PMC Article
Identifying factors contributing to increased susceptibility to COVID-19 risk: a systematic review of Mendelian randomization studies.
Luo S, Liang Y, Wong THT, Schooling CM, Au Yeung SL
Int J Epidemiol 2022 Aug 10;51(4):1088-1105. doi: 10.1093/ije/dyac076. PMID: 35445260Free PMC Article
Systematic review of drug effects in humans and models with surfactant-processing disease.
Klay D, Hoffman TW, Harmsze AM, Grutters JC, van Moorsel CHM
Eur Respir Rev 2018 Sep 30;27(149) Epub 2018 Jul 11 doi: 10.1183/16000617.0135-2017. PMID: 29997245Free PMC Article

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