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Hypercholesterolemia, susceptibility to

MedGen UID:
865112
Concept ID:
C4016675
Finding
Synonym: HYPERCHOLESTEROLEMIA, SUSCEPTIBILITY TO
 
OMIM®: 604088

Professional guidelines

PubMed

Bigossi M, Siddiqui MK
Eur J Prev Cardiol 2024 May 11;31(7):e59-e61. doi: 10.1093/eurjpc/zwac258. PMID: 36356117
Schwartz MLB, Williams MS, Murray MF
JAMA 2017 Apr 18;317(15):1527-1528. doi: 10.1001/jama.2017.1533. PMID: 28288260
Tichý L, Freiberger T, Zapletalová P, Soška V, Ravčuková B, Fajkusová L
Atherosclerosis 2012 Aug;223(2):401-8. Epub 2012 May 23 doi: 10.1016/j.atherosclerosis.2012.05.014. PMID: 22698793

Recent clinical studies

Etiology

O'Sullivan JW, Raghavan S, Marquez-Luna C, Luzum JA, Damrauer SM, Ashley EA, O'Donnell CJ, Willer CJ, Natarajan P; American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
Circulation 2022 Aug 23;146(8):e93-e118. Epub 2022 Jul 18 doi: 10.1161/CIR.0000000000001077. PMID: 35862132Free PMC Article
Abegaz SB
Biomed Res Int 2021;2021:6629060. Epub 2021 Jan 23 doi: 10.1155/2021/6629060. PMID: 33564677Free PMC Article
Meshkov A, Ershova A, Kiseleva A, Zotova E, Sotnikova E, Petukhova A, Zharikova A, Malyshev P, Rozhkova T, Blokhina A, Limonova A, Ramensky V, Divashuk M, Khasanova Z, Bukaeva A, Kurilova O, Skirko O, Pokrovskaya M, Mikova V, Snigir E, Akinshina A, Mitrofanov S, Kashtanova D, Makarov V, Kukharchuk V, Boytsov S, Yudin S, Drapkina O
Genes (Basel) 2021 Jan 6;12(1) doi: 10.3390/genes12010066. PMID: 33418990Free PMC Article
Schachter M
Fundam Clin Pharmacol 2005 Feb;19(1):117-25. doi: 10.1111/j.1472-8206.2004.00299.x. PMID: 15660968
Libby P
Nature 2002 Dec 19-26;420(6917):868-74. doi: 10.1038/nature01323. PMID: 12490960

Diagnosis

O'Sullivan JW, Raghavan S, Marquez-Luna C, Luzum JA, Damrauer SM, Ashley EA, O'Donnell CJ, Willer CJ, Natarajan P; American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
Circulation 2022 Aug 23;146(8):e93-e118. Epub 2022 Jul 18 doi: 10.1161/CIR.0000000000001077. PMID: 35862132Free PMC Article
Di Taranto MD, Giacobbe C, Palma D, Iannuzzo G, Gentile M, Calcaterra I, Guardamagna O, Auricchio R, Di Minno MND, Fortunato G
Clin Genet 2021 Nov;100(5):529-541. Epub 2021 Aug 3 doi: 10.1111/cge.14036. PMID: 34297352Free PMC Article
Wang J, Dron JS, Ban MR, Robinson JF, McIntyre AD, Alazzam M, Zhao PJ, Dilliott AA, Cao H, Huff MW, Rhainds D, Low-Kam C, Dubé MP, Lettre G, Tardif JC, Hegele RA
Arterioscler Thromb Vasc Biol 2016 Dec;36(12):2439-2445. Epub 2016 Oct 20 doi: 10.1161/ATVBAHA.116.308027. PMID: 27765764
Onorato A, Sturm AC
Circulation 2016 Apr 5;133(14):e587-9. doi: 10.1161/CIRCULATIONAHA.115.020701. PMID: 27045133
Tsao CW, Vasan RS
Int J Epidemiol 2015 Dec;44(6):1800-13. doi: 10.1093/ije/dyv337. PMID: 26705418Free PMC Article

Therapy

O'Sullivan JW, Raghavan S, Marquez-Luna C, Luzum JA, Damrauer SM, Ashley EA, O'Donnell CJ, Willer CJ, Natarajan P; American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
Circulation 2022 Aug 23;146(8):e93-e118. Epub 2022 Jul 18 doi: 10.1161/CIR.0000000000001077. PMID: 35862132Free PMC Article
Ference BA, Ray KK, Catapano AL, Ference TB, Burgess S, Neff DR, Oliver-Williams C, Wood AM, Butterworth AS, Di Angelantonio E, Danesh J, Kastelein JJP, Nicholls SJ
N Engl J Med 2019 Mar 14;380(11):1033-1042. doi: 10.1056/NEJMoa1806747. PMID: 30865797Free PMC Article
Onorato A, Sturm AC
Circulation 2016 Apr 5;133(14):e587-9. doi: 10.1161/CIRCULATIONAHA.115.020701. PMID: 27045133
Bouhairie VE, Goldberg AC
Cardiol Clin 2015 May;33(2):169-79. doi: 10.1016/j.ccl.2015.01.001. PMID: 25939291Free PMC Article
Schachter M
Fundam Clin Pharmacol 2005 Feb;19(1):117-25. doi: 10.1111/j.1472-8206.2004.00299.x. PMID: 15660968

Prognosis

Forrest IS, Duffy Á, Park JK, Vy HMT, Pasquale LR, Nadkarni GN, Cho JH, Do R
Cell Rep Med 2024 May 21;5(5):101518. Epub 2024 Apr 19 doi: 10.1016/j.xcrm.2024.101518. PMID: 38642551Free PMC Article
O'Sullivan JW, Raghavan S, Marquez-Luna C, Luzum JA, Damrauer SM, Ashley EA, O'Donnell CJ, Willer CJ, Natarajan P; American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
Circulation 2022 Aug 23;146(8):e93-e118. Epub 2022 Jul 18 doi: 10.1161/CIR.0000000000001077. PMID: 35862132Free PMC Article
Di Taranto MD, Giacobbe C, Palma D, Iannuzzo G, Gentile M, Calcaterra I, Guardamagna O, Auricchio R, Di Minno MND, Fortunato G
Clin Genet 2021 Nov;100(5):529-541. Epub 2021 Aug 3 doi: 10.1111/cge.14036. PMID: 34297352Free PMC Article
Hadjiphilippou S, Ray KK
Circ Res 2019 Feb;124(3):354-363. doi: 10.1161/CIRCRESAHA.118.313245. PMID: 30702991
Wang J, Dron JS, Ban MR, Robinson JF, McIntyre AD, Alazzam M, Zhao PJ, Dilliott AA, Cao H, Huff MW, Rhainds D, Low-Kam C, Dubé MP, Lettre G, Tardif JC, Hegele RA
Arterioscler Thromb Vasc Biol 2016 Dec;36(12):2439-2445. Epub 2016 Oct 20 doi: 10.1161/ATVBAHA.116.308027. PMID: 27765764

Clinical prediction guides

O'Sullivan JW, Raghavan S, Marquez-Luna C, Luzum JA, Damrauer SM, Ashley EA, O'Donnell CJ, Willer CJ, Natarajan P; American Heart Association Council on Genomic and Precision Medicine; Council on Clinical Cardiology; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; and Council on Peripheral Vascular Disease
Circulation 2022 Aug 23;146(8):e93-e118. Epub 2022 Jul 18 doi: 10.1161/CIR.0000000000001077. PMID: 35862132Free PMC Article
Di Taranto MD, Giacobbe C, Palma D, Iannuzzo G, Gentile M, Calcaterra I, Guardamagna O, Auricchio R, Di Minno MND, Fortunato G
Clin Genet 2021 Nov;100(5):529-541. Epub 2021 Aug 3 doi: 10.1111/cge.14036. PMID: 34297352Free PMC Article
Ference BA, Ray KK, Catapano AL, Ference TB, Burgess S, Neff DR, Oliver-Williams C, Wood AM, Butterworth AS, Di Angelantonio E, Danesh J, Kastelein JJP, Nicholls SJ
N Engl J Med 2019 Mar 14;380(11):1033-1042. doi: 10.1056/NEJMoa1806747. PMID: 30865797Free PMC Article
Hadjiphilippou S, Ray KK
Circ Res 2019 Feb;124(3):354-363. doi: 10.1161/CIRCRESAHA.118.313245. PMID: 30702991
Wang J, Dron JS, Ban MR, Robinson JF, McIntyre AD, Alazzam M, Zhao PJ, Dilliott AA, Cao H, Huff MW, Rhainds D, Low-Kam C, Dubé MP, Lettre G, Tardif JC, Hegele RA
Arterioscler Thromb Vasc Biol 2016 Dec;36(12):2439-2445. Epub 2016 Oct 20 doi: 10.1161/ATVBAHA.116.308027. PMID: 27765764

Recent systematic reviews

Rastogi A, Dogra H, Jude EB
Diabetes Metab Syndr 2021 Sep-Oct;15(5):102204. Epub 2021 Jul 9 doi: 10.1016/j.dsx.2021.102204. PMID: 34303918Free PMC Article
Peng J, Wu X, Wang S, Zhang S, Wang X, Liu Z, Hong J, Ye P, Lin J
Atheroscler Suppl 2019 Mar;36:12-18. Epub 2019 Jan 29 doi: 10.1016/j.atherosclerosissup.2019.01.003. PMID: 30876527
Lee S, Akioyamen LE, Aljenedil S, Rivière JB, Ruel I, Genest J
Eur J Prev Cardiol 2019 Aug;26(12):1262-1270. Epub 2019 Feb 12 doi: 10.1177/2047487319829746. PMID: 30755017
Hong XY, Lin J, Gu WW
J Cell Physiol 2019 Jun;234(6):8221-8232. Epub 2018 Oct 14 doi: 10.1002/jcp.27633. PMID: 30317627
Alhababi D, Zayed H
Atherosclerosis 2018 Dec;279:62-72. Epub 2018 Oct 19 doi: 10.1016/j.atherosclerosis.2018.10.022. PMID: 30415195

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