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FMO3 activity, decreased

MedGen UID:
864537
Concept ID:
C4016100
Finding
Synonym: FMO3 ACTIVITY, DECREASED
 
OMIM®: 136132

Recent clinical studies

Etiology

Borrego-Soto G, Perez-Paramo YX, Hernández-Cabrera F, Alvarado-Monroy FM, Borrego G, Robles-Zamora A, Lazarus P, Rojas-Martinez A
Pharmacol Res Perspect 2023 Oct;11(5):e01142. doi: 10.1002/prp2.1142. PMID: 37787014Free PMC Article
Cleary Y, Kletzl H, Grimsey P, Heinig K, Ogungbenro K, Silber Baumann HE, Frey N, Aarons L, Galetin A, Gertz M
Clin Pharmacokinet 2023 Jun;62(6):891-904. Epub 2023 May 6 doi: 10.1007/s40262-023-01241-7. PMID: 37148485Free PMC Article
Wang X, Zhao J, Wen T, Liao X, Luo B
Pharmacology 2021;106(3-4):202-210. Epub 2020 Sep 30 doi: 10.1159/000510327. PMID: 32998136
Morandi A, Zusi C, Corradi M, Olivieri F, Piona C, Fornari E, Maffeis C
Int J Obes (Lond) 2018 Jun;42(6):1243-1248. Epub 2018 May 24 doi: 10.1038/s41366-018-0100-7. PMID: 29795455
Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, Schuetz E, Rettie AE, Leeder JS, Thummel KE, Prasad B
J Pharmacol Exp Ther 2017 Nov;363(2):265-274. Epub 2017 Aug 17 doi: 10.1124/jpet.117.243113. PMID: 28819071Free PMC Article

Diagnosis

Yamada T, Mino Y, Naito T, Kawakami J
J Infect Chemother 2019 Dec;25(12):1019-1025. Epub 2019 Jun 22 doi: 10.1016/j.jiac.2019.05.032. PMID: 31239195
Morandi A, Zusi C, Corradi M, Olivieri F, Piona C, Fornari E, Maffeis C
Int J Obes (Lond) 2018 Jun;42(6):1243-1248. Epub 2018 May 24 doi: 10.1038/s41366-018-0100-7. PMID: 29795455
Wilson A, Teft WA, Morse BL, Choi YH, Woolsey S, DeGorter MK, Hegele RA, Tirona RG, Kim RB
Dig Dis Sci 2015 Dec;60(12):3620-30. Epub 2015 Jul 10 doi: 10.1007/s10620-015-3797-3. PMID: 26160437
D'Angelo R, Scimone C, Esposito T, Bruschetta D, Rinaldi C, Ruggeri A, Sidoti A
J Med Case Rep 2014 Oct 6;8:328. doi: 10.1186/1752-1947-8-328. PMID: 25288227Free PMC Article
Cashman JR, Bi YA, Lin J, Youil R, Knight M, Forrest S, Treacy E
Chem Res Toxicol 1997 Aug;10(8):837-41. doi: 10.1021/tx9700533. PMID: 9282831

Therapy

Cleary Y, Kletzl H, Grimsey P, Heinig K, Ogungbenro K, Silber Baumann HE, Frey N, Aarons L, Galetin A, Gertz M
Clin Pharmacokinet 2023 Jun;62(6):891-904. Epub 2023 May 6 doi: 10.1007/s40262-023-01241-7. PMID: 37148485Free PMC Article
Wang X, Zhao J, Wen T, Liao X, Luo B
Pharmacology 2021;106(3-4):202-210. Epub 2020 Sep 30 doi: 10.1159/000510327. PMID: 32998136
Tanino T, Bando T, Komada A, Nojiri Y, Okada Y, Ueda Y, Sakurai E
Drug Metab Dispos 2017 Nov;45(11):1189-1196. Epub 2017 Jul 31 doi: 10.1124/dmd.117.076570. PMID: 28760731
Taghavi T, St Helen G, Benowitz NL, Tyndale RF
Pharmacogenet Genomics 2017 Apr;27(4):143-154. doi: 10.1097/FPC.0000000000000269. PMID: 28178031Free PMC Article
Lattard V, Zhang J, Tran Q, Furnes B, Schlenk D, Cashman JR
Drug Metab Dispos 2003 Jul;31(7):854-60. doi: 10.1124/dmd.31.7.854. PMID: 12814961

Prognosis

Cleary Y, Kletzl H, Grimsey P, Heinig K, Ogungbenro K, Silber Baumann HE, Frey N, Aarons L, Galetin A, Gertz M
Clin Pharmacokinet 2023 Jun;62(6):891-904. Epub 2023 May 6 doi: 10.1007/s40262-023-01241-7. PMID: 37148485Free PMC Article
Lv S, Wang Y, Zhang W, Shang H
Heart 2022 May 25;108(12):917-922. doi: 10.1136/heartjnl-2021-320054. PMID: 34611047
Wang X, Zhao J, Wen T, Liao X, Luo B
Pharmacology 2021;106(3-4):202-210. Epub 2020 Sep 30 doi: 10.1159/000510327. PMID: 32998136
Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, Schuetz E, Rettie AE, Leeder JS, Thummel KE, Prasad B
J Pharmacol Exp Ther 2017 Nov;363(2):265-274. Epub 2017 Aug 17 doi: 10.1124/jpet.117.243113. PMID: 28819071Free PMC Article
Phillips IR, Shephard EA
Trends Pharmacol Sci 2008 Jun;29(6):294-301. Epub 2008 Apr 16 doi: 10.1016/j.tips.2008.03.004. PMID: 18423897

Clinical prediction guides

Borrego-Soto G, Perez-Paramo YX, Hernández-Cabrera F, Alvarado-Monroy FM, Borrego G, Robles-Zamora A, Lazarus P, Rojas-Martinez A
Pharmacol Res Perspect 2023 Oct;11(5):e01142. doi: 10.1002/prp2.1142. PMID: 37787014Free PMC Article
Kong L, Chen J, Ji X, Qin Q, Yang H, Liu D, Li D, Sun M
J Exp Clin Cancer Res 2021 Jan 7;40(1):18. doi: 10.1186/s13046-020-01782-w. PMID: 33413501Free PMC Article
Perez-Paramo YX, Chen G, Ashmore JH, Watson CJW, Nasrin S, Adams-Haduch J, Wang R, Gao YT, Koh WP, Yuan JM, Lazarus P
Cancer Epidemiol Biomarkers Prev 2019 Feb;28(2):311-320. Epub 2018 Oct 31 doi: 10.1158/1055-9965.EPI-18-0669. PMID: 30381441Free PMC Article
Ramana P, Schejbal J, Houthoofd K, Martens J, Adams E, Augustijns P, Glatz Z, Van Schepdael A
Electrophoresis 2018 Apr;39(7):981-988. Epub 2018 Jan 19 doi: 10.1002/elps.201700434. PMID: 29315710
Xu M, Bhatt DK, Yeung CK, Claw KG, Chaudhry AS, Gaedigk A, Pearce RE, Broeckel U, Gaedigk R, Nickerson DA, Schuetz E, Rettie AE, Leeder JS, Thummel KE, Prasad B
J Pharmacol Exp Ther 2017 Nov;363(2):265-274. Epub 2017 Aug 17 doi: 10.1124/jpet.117.243113. PMID: 28819071Free PMC Article

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