U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Increased responsiveness to growth hormone

MedGen UID:
854788
•Concept ID:
C3888131
•
Finding
Synonym: INCREASED RESPONSIVENESS TO GROWTH HORMONE
 
OMIM®: 600946; 604271

Professional guidelines

PubMed

Genetic evaluation in children with short stature.
Zhou E, Hauser BR, Jee YH
Curr Opin Pediatr 2021 Aug 1;33(4):458-463. doi: 10.1097/MOP.0000000000001033. PMID: 34101704Free PMC Article
Glycemic Monitoring and Management in Advanced Chronic Kidney Disease.
Galindo RJ, Beck RW, Scioscia MF, Umpierrez GE, Tuttle KR
Endocr Rev 2020 Oct 1;41(5):756-74. doi: 10.1210/endrev/bnaa017. PMID: 32455432Free PMC Article
Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective.
Collett-Solberg PF, Ambler G, Backeljauw PF, Bidlingmaier M, Biller BMK, Boguszewski MCS, Cheung PT, Choong CSY, Cohen LE, Cohen P, Dauber A, Deal CL, Gong C, Hasegawa Y, Hoffman AR, Hofman PL, Horikawa R, Jorge AAL, Juul A, Kamenický P, Khadilkar V, Kopchick JJ, Kriström B, Lopes MLA, Luo X, Miller BS, Misra M, Netchine I, Radovick S, Ranke MB, Rogol AD, Rosenfeld RG, Saenger P, Wit JM, Woelfle J
Horm Res Paediatr 2019;92(1):1-14. Epub 2019 Sep 12 doi: 10.1159/000502231. PMID: 31514194Free PMC Article

Recent clinical studies

Etiology

Secondary diabetes mellitus in acromegaly.
Moustaki M, Paschou SA, Xekouki P, Kotsa K, Peppa M, Psaltopoulou T, Kalantaridou S, Vryonidou A
Endocrine 2023 Jul;81(1):1-15. Epub 2023 Mar 8 doi: 10.1007/s12020-023-03339-1. PMID: 36882643Free PMC Article
Response to growth hormone treatment in patients with sufficient secretion.
Úbeda Trujillo RM, Escribano Sanz P, García Castellanos MT, de Arriba Muñoz A, Vara Callau M, Labarta Aizpún JI
Endocrinol Diabetes Nutr (Engl Ed) 2023 May;70(5):326-334. Epub 2022 Nov 25 doi: 10.1016/j.endien.2022.02.021. PMID: 36443195
Endocrine responses of the stress system to different types of exercise.
Athanasiou N, Bogdanis GC, Mastorakos G
Rev Endocr Metab Disord 2023 Apr;24(2):251-266. Epub 2022 Oct 15 doi: 10.1007/s11154-022-09758-1. PMID: 36242699Free PMC Article
Growth Hormone and Counterregulation in the Pathogenesis of Diabetes.
Dong X, Su L, Patti ME
Curr Diab Rep 2022 Oct;22(10):511-524. Epub 2022 Aug 24 doi: 10.1007/s11892-022-01488-7. PMID: 36001217Free PMC Article
Growth and development in type 1 diabetes.
Koren D
Curr Opin Endocrinol Diabetes Obes 2022 Feb 1;29(1):57-64. doi: 10.1097/MED.0000000000000694. PMID: 34864760

Diagnosis

Short stature related to Growth Hormone Insensitivity (GHI) in childhood.
Mastromauro C, Giannini C, Chiarelli F
Front Endocrinol (Lausanne) 2023;14:1141039. Epub 2023 Mar 15 doi: 10.3389/fendo.2023.1141039. PMID: 37008935Free PMC Article
Secondary diabetes mellitus in acromegaly.
Moustaki M, Paschou SA, Xekouki P, Kotsa K, Peppa M, Psaltopoulou T, Kalantaridou S, Vryonidou A
Endocrine 2023 Jul;81(1):1-15. Epub 2023 Mar 8 doi: 10.1007/s12020-023-03339-1. PMID: 36882643Free PMC Article
Growth Hormone and Counterregulation in the Pathogenesis of Diabetes.
Dong X, Su L, Patti ME
Curr Diab Rep 2022 Oct;22(10):511-524. Epub 2022 Aug 24 doi: 10.1007/s11892-022-01488-7. PMID: 36001217Free PMC Article
Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective.
Collett-Solberg PF, Ambler G, Backeljauw PF, Bidlingmaier M, Biller BMK, Boguszewski MCS, Cheung PT, Choong CSY, Cohen LE, Cohen P, Dauber A, Deal CL, Gong C, Hasegawa Y, Hoffman AR, Hofman PL, Horikawa R, Jorge AAL, Juul A, Kamenický P, Khadilkar V, Kopchick JJ, Kriström B, Lopes MLA, Luo X, Miller BS, Misra M, Netchine I, Radovick S, Ranke MB, Rogol AD, Rosenfeld RG, Saenger P, Wit JM, Woelfle J
Horm Res Paediatr 2019;92(1):1-14. Epub 2019 Sep 12 doi: 10.1159/000502231. PMID: 31514194Free PMC Article
Detraining: loss of training-induced physiological and performance adaptations. Part I: short term insufficient training stimulus.
Mujika I, Padilla S
Sports Med 2000 Aug;30(2):79-87. doi: 10.2165/00007256-200030020-00002. PMID: 10966148

Therapy

Growth Hormone and Counterregulation in the Pathogenesis of Diabetes.
Dong X, Su L, Patti ME
Curr Diab Rep 2022 Oct;22(10):511-524. Epub 2022 Aug 24 doi: 10.1007/s11892-022-01488-7. PMID: 36001217Free PMC Article
Growth hormone, arginine and exercise.
Kanaley JA
Curr Opin Clin Nutr Metab Care 2008 Jan;11(1):50-4. doi: 10.1097/MCO.0b013e3282f2b0ad. PMID: 18090659
Growth hormone therapy.
Wit JM
Best Pract Res Clin Endocrinol Metab 2002 Sep;16(3):483-503. doi: 10.1053/beem.2002.0206. PMID: 12464230
Growth hormone-releasing peptides.
Ghigo E, Arvat E, Muccioli G, Camanni F
Eur J Endocrinol 1997 May;136(5):445-60. doi: 10.1530/eje.0.1360445. PMID: 9186261
Growth hormone releasing hormone.
Grossman A, Savage MO, Besser GM
Clin Endocrinol Metab 1986 Aug;15(3):607-27. doi: 10.1016/s0300-595x(86)80012-3. PMID: 2429796

Prognosis

Response to growth hormone treatment in patients with sufficient secretion.
Úbeda Trujillo RM, Escribano Sanz P, García Castellanos MT, de Arriba Muñoz A, Vara Callau M, Labarta Aizpún JI
Endocrinol Diabetes Nutr (Engl Ed) 2023 May;70(5):326-334. Epub 2022 Nov 25 doi: 10.1016/j.endien.2022.02.021. PMID: 36443195
Role of growth hormone in hepatic and intestinal triglyceride-rich lipoprotein metabolism.
Maraninchi M, Calabrese A, Nogueira JP, Castinetti F, Mancini J, Mourre F, Piétri L, Bénamo E, Albarel F, Morange I, Dupont-Roussel J, Nicolay A, Brue T, Béliard S, Valéro R
J Clin Lipidol 2021 Sep-Oct;15(5):712-723. Epub 2021 Aug 16 doi: 10.1016/j.jacl.2021.08.003. PMID: 34462238
Individual sensitivity to growth hormone replacement in adults.
Boguszewski CL
Rev Endocr Metab Disord 2021 Mar;22(1):117-124. Epub 2020 Oct 7 doi: 10.1007/s11154-020-09605-1. PMID: 33026599
Growth hormone therapy.
Wit JM
Best Pract Res Clin Endocrinol Metab 2002 Sep;16(3):483-503. doi: 10.1053/beem.2002.0206. PMID: 12464230
Growth hormone and athletes.
Macintyre JG
Sports Med 1987 Mar-Apr;4(2):129-42. doi: 10.2165/00007256-198704020-00004. PMID: 3299611

Clinical prediction guides

Response to growth hormone treatment in patients with sufficient secretion.
Úbeda Trujillo RM, Escribano Sanz P, García Castellanos MT, de Arriba Muñoz A, Vara Callau M, Labarta Aizpún JI
Endocrinol Diabetes Nutr (Engl Ed) 2023 May;70(5):326-334. Epub 2022 Nov 25 doi: 10.1016/j.endien.2022.02.021. PMID: 36443195
Growth Hormone Response to Oral Glucose Load: From Normal to Pathological Conditions.
Hage M, Kamenický P, Chanson P
Neuroendocrinology 2019;108(3):244-255. Epub 2019 Jan 25 doi: 10.1159/000497214. PMID: 30685760
Growth hormone therapy.
Wit JM
Best Pract Res Clin Endocrinol Metab 2002 Sep;16(3):483-503. doi: 10.1053/beem.2002.0206. PMID: 12464230
Growth hormone and athletes.
Macintyre JG
Sports Med 1987 Mar-Apr;4(2):129-42. doi: 10.2165/00007256-198704020-00004. PMID: 3299611
Endorphins and exercise.
Harber VJ, Sutton JR
Sports Med 1984 Mar-Apr;1(2):154-71. doi: 10.2165/00007256-198401020-00004. PMID: 6091217

Recent systematic reviews

Efficacy of intra-ovarian injection of autologous platelet-rich plasma in women with poor responders: a systematic review and meta-analysis.
Vahabi Dastjerdi M, Sheibani S, Taheri M, Hezarcheshmeh FK, Jahangirian J, Jazayeri M, Hosseinirad H, Doohandeh T, Valizadeh R
Arch Gynecol Obstet 2024 Jun;309(6):2323-2338. Epub 2024 Apr 8 doi: 10.1007/s00404-024-07442-0. PMID: 38589612
Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis.
Derakhshan A, Peeters RP, Taylor PN, Bliddal S, Carty DM, Meems M, Vaidya B, Chen L, Knight BA, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan CM, French R, Boucai L, Vafeiadi M, Grineva EN, Pop VJM, Vrijkotte TG, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Rebagliato M, Lu X, Pirzada A, Männistö T, Delles C, Feldt-Rasmussen U, Alexander EK, Nelson SM, Chaker L, Pearce EN, Guxens M, Steegers EAP, Walsh JP, Korevaar TIM
Lancet Diabetes Endocrinol 2020 Jun;8(6):501-510. doi: 10.1016/S2213-8587(20)30061-9. PMID: 32445737Free PMC Article
Vitamin D Supplementation during Pregnancy: An Evidence Analysis Center Systematic Review and Meta-Analysis.
Gallo S, McDermid JM, Al-Nimr RI, Hakeem R, Moreschi JM, Pari-Keener M, Stahnke B, Papoutsakis C, Handu D, Cheng FW
J Acad Nutr Diet 2020 May;120(5):898-924.e4. Epub 2019 Oct 25 doi: 10.1016/j.jand.2019.07.002. PMID: 31669079
Safety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data.
Islam RM, Bell RJ, Green S, Page MJ, Davis SR
Lancet Diabetes Endocrinol 2019 Oct;7(10):754-766. Epub 2019 Jul 25 doi: 10.1016/S2213-8587(19)30189-5. PMID: 31353194
The physiology and clinical utility of anti-Mullerian hormone in women.
Dewailly D, Andersen CY, Balen A, Broekmans F, Dilaver N, Fanchin R, Griesinger G, Kelsey TW, La Marca A, Lambalk C, Mason H, Nelson SM, Visser JA, Wallace WH, Anderson RA
Hum Reprod Update 2014 May-Jun;20(3):370-85. Epub 2014 Jan 14 doi: 10.1093/humupd/dmt062. PMID: 24430863

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • OMIM
      Related records in OMIM
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed
    • PubMed (OMIM)
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...