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Aplastic anemia, susceptibility to

MedGen UID:
394560
•Concept ID:
C2684859
•
Finding
Synonym: APLASTIC ANEMIA, SUSCEPTIBILITY TO
 
Monarch Initiative: MONDO:0800414
OMIM®: 147570; 607444; 609135

Professional guidelines

PubMed

Treatment of Fanconi Anemia-Associated Head and Neck Cancer: Opportunities to Improve Outcomes.
Lee RH, Kang H, Yom SS, Smogorzewska A, Johnson DE, Grandis JR
Clin Cancer Res 2021 Oct 1;27(19):5168-5187. doi: 10.1158/1078-0432.CCR-21-1259. PMID: 34045293Free PMC Article
Management of the refractory aplastic anemia patient: what are the options?
Marsh JC, Kulasekararaj AG
Blood 2013 Nov 21;122(22):3561-7. Epub 2013 Sep 19 doi: 10.1182/blood-2013-05-498279. PMID: 24052548
Clinical utility gene card for: Diamond-Blackfan anemia--update 2013.
Vlachos A, Dahl N, Dianzani I, Lipton JM
Eur J Hum Genet 2013 Oct;21(10) Epub 2013 Mar 6 doi: 10.1038/ejhg.2013.34. PMID: 23463023Free PMC Article

Recent clinical studies

Etiology

How we('ll) treat paroxysmal nocturnal haemoglobinuria: diving into the future.
Risitano AM, Peffault de Latour R
Br J Haematol 2022 Jan;196(2):288-303. Epub 2021 Aug 5 doi: 10.1111/bjh.17753. PMID: 34355382Free PMC Article
Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria.
Colden MA, Kumar S, Munkhbileg B, Babushok DV
Front Immunol 2021;12:830172. Epub 2022 Jan 28 doi: 10.3389/fimmu.2021.830172. PMID: 35154088Free PMC Article
Thrombopoietin receptor agonists: ten years later.
Ghanima W, Cooper N, Rodeghiero F, Godeau B, Bussel JB
Haematologica 2019 Jun;104(6):1112-1123. Epub 2019 May 9 doi: 10.3324/haematol.2018.212845. PMID: 31073079Free PMC Article
How I treat myelodysplastic syndromes of childhood.
Locatelli F, Strahm B
Blood 2018 Mar 29;131(13):1406-1414. Epub 2018 Feb 8 doi: 10.1182/blood-2017-09-765214. PMID: 29438960
Crises in Sickle Cell Disease.
Novelli EM, Gladwin MT
Chest 2016 Apr;149(4):1082-93. Epub 2015 Dec 28 doi: 10.1016/j.chest.2015.12.016. PMID: 26836899Free PMC Article

Diagnosis

Insights Into the Emergence of Paroxysmal Nocturnal Hemoglobinuria.
Colden MA, Kumar S, Munkhbileg B, Babushok DV
Front Immunol 2021;12:830172. Epub 2022 Jan 28 doi: 10.3389/fimmu.2021.830172. PMID: 35154088Free PMC Article
Pathogenesis of aplastic anemia.
Wang L, Liu H
Hematology 2019 Dec;24(1):559-566. doi: 10.1080/16078454.2019.1642548. PMID: 31315542
Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts.
Shallis RM, Ahmad R, Zeidan AM
Eur J Haematol 2018 Dec;101(6):711-720. Epub 2018 Oct 10 doi: 10.1111/ejh.13153. PMID: 30055055
How I treat myelodysplastic syndromes of childhood.
Locatelli F, Strahm B
Blood 2018 Mar 29;131(13):1406-1414. Epub 2018 Feb 8 doi: 10.1182/blood-2017-09-765214. PMID: 29438960
Human parvovirus B19.
Heegaard ED, Brown KE
Clin Microbiol Rev 2002 Jul;15(3):485-505. doi: 10.1128/CMR.15.3.485-505.2002. PMID: 12097253Free PMC Article

Therapy

How we('ll) treat paroxysmal nocturnal haemoglobinuria: diving into the future.
Risitano AM, Peffault de Latour R
Br J Haematol 2022 Jan;196(2):288-303. Epub 2021 Aug 5 doi: 10.1111/bjh.17753. PMID: 34355382Free PMC Article
Thrombopoietin receptor agonists: ten years later.
Ghanima W, Cooper N, Rodeghiero F, Godeau B, Bussel JB
Haematologica 2019 Jun;104(6):1112-1123. Epub 2019 May 9 doi: 10.3324/haematol.2018.212845. PMID: 31073079Free PMC Article
Iron toxicity - Its effect on the bone marrow.
Isidori A, Borin L, Elli E, Latagliata R, Martino B, Palumbo G, Pilo F, Loscocco F, Visani G, Cianciulli P
Blood Rev 2018 Nov;32(6):473-479. Epub 2018 Apr 13 doi: 10.1016/j.blre.2018.04.004. PMID: 29699840
Crises in Sickle Cell Disease.
Novelli EM, Gladwin MT
Chest 2016 Apr;149(4):1082-93. Epub 2015 Dec 28 doi: 10.1016/j.chest.2015.12.016. PMID: 26836899Free PMC Article
Hematopoietic stem cells.
Trigg ME
Pediatrics 2004 Apr;113(4 Suppl):1051-7. PMID: 15060199

Prognosis

Acinetobacter spp. bloodstream infection in hematological patients: a 10-year single-center study.
Li J, Feng X, Wang J, Lin Q, Zheng Y, Zhang F, Mi Y, Zhu X, Jiang E, Xiao Z, Wang J, Feng S
BMC Infect Dis 2023 Nov 14;23(1):796. doi: 10.1186/s12879-023-08789-6. PMID: 37964192Free PMC Article
Post-COVID-19 hematologic complications: a systematic review.
Alahyari S, Moradi M, Rajaeinejad M, Jalaeikhoo H
Expert Rev Hematol 2022 Jun;15(6):539-546. Epub 2022 May 26 doi: 10.1080/17474086.2022.2080051. PMID: 35584541
How we('ll) treat paroxysmal nocturnal haemoglobinuria: diving into the future.
Risitano AM, Peffault de Latour R
Br J Haematol 2022 Jan;196(2):288-303. Epub 2021 Aug 5 doi: 10.1111/bjh.17753. PMID: 34355382Free PMC Article
PNH Clones for Aplastic Anemia with Immunosuppressive Therapy: A Systematic Review and Meta-Analysis.
Tu J, Pan H, Li R, Wang Z, Lian Y, Li W, Shi J, Fang L
Acta Haematol 2021;144(1):34-43. Epub 2020 Sep 2 doi: 10.1159/000506387. PMID: 32877903
Paroxysmal nocturnal haemoglobinuria (PNH): novel therapies for an ancient disease.
Luzzatto L, Karadimitris A
Br J Haematol 2020 Nov;191(4):579-586. doi: 10.1111/bjh.17147. PMID: 33190263

Clinical prediction guides

Post-COVID-19 hematologic complications: a systematic review.
Alahyari S, Moradi M, Rajaeinejad M, Jalaeikhoo H
Expert Rev Hematol 2022 Jun;15(6):539-546. Epub 2022 May 26 doi: 10.1080/17474086.2022.2080051. PMID: 35584541
PNH Clones for Aplastic Anemia with Immunosuppressive Therapy: A Systematic Review and Meta-Analysis.
Tu J, Pan H, Li R, Wang Z, Lian Y, Li W, Shi J, Fang L
Acta Haematol 2021;144(1):34-43. Epub 2020 Sep 2 doi: 10.1159/000506387. PMID: 32877903
How I treat myelodysplastic syndromes of childhood.
Locatelli F, Strahm B
Blood 2018 Mar 29;131(13):1406-1414. Epub 2018 Feb 8 doi: 10.1182/blood-2017-09-765214. PMID: 29438960
Patients with Fanconi anemia and AML have different cytogenetic clones than de novo cases of AML.
Rochowski A, Olson SB, Alonzo TA, Gerbing RB, Lange BJ, Alter BP
Pediatr Blood Cancer 2012 Nov;59(5):922-4. Epub 2012 Apr 19 doi: 10.1002/pbc.24168. PMID: 22517793Free PMC Article
Hematopoietic stem cells.
Trigg ME
Pediatrics 2004 Apr;113(4 Suppl):1051-7. PMID: 15060199

Recent systematic reviews

Longitudinal clinical manifestations of Fanconi anemia: A systematized review.
Hoover A, Turcotte LM, Phelan R, Barbus C, Rayannavar A, Miller BS, Reardon EE, Theis-Mahon N, MacMillan ML
Blood Rev 2024 Nov;68:101225. Epub 2024 Aug 2 doi: 10.1016/j.blre.2024.101225. PMID: 39107201Free PMC Article
Post-COVID-19 hematologic complications: a systematic review.
Alahyari S, Moradi M, Rajaeinejad M, Jalaeikhoo H
Expert Rev Hematol 2022 Jun;15(6):539-546. Epub 2022 May 26 doi: 10.1080/17474086.2022.2080051. PMID: 35584541
Treatment of Fanconi Anemia-Associated Head and Neck Cancer: Opportunities to Improve Outcomes.
Lee RH, Kang H, Yom SS, Smogorzewska A, Johnson DE, Grandis JR
Clin Cancer Res 2021 Oct 1;27(19):5168-5187. doi: 10.1158/1078-0432.CCR-21-1259. PMID: 34045293Free PMC Article
PNH Clones for Aplastic Anemia with Immunosuppressive Therapy: A Systematic Review and Meta-Analysis.
Tu J, Pan H, Li R, Wang Z, Lian Y, Li W, Shi J, Fang L
Acta Haematol 2021;144(1):34-43. Epub 2020 Sep 2 doi: 10.1159/000506387. PMID: 32877903

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