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Squamous cell lung carcinoma

MedGen UID:
56202
Concept ID:
C0149782
Neoplastic Process
Synonyms: Lung cancer, squamous cell, somatic; Squamous cell carcinoma of lung
SNOMED CT: Squamous cell carcinoma of lung (254634000); Epidermoid carcinoma of lung (254634000); SCC - Squamous cell carcinoma of lung (254634000)
 
HPO: HP:0030359
Monarch Initiative: MONDO:0005097

Definition

A type of non-small cell lung carcinoma that is derived from stratified squamous epithelial cells. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Squamous cell lung carcinoma

Professional guidelines

PubMed

Lu Y, Tang H, Huang P, Wang J, Deng P, Li Y, Zheng J, Weng L
Int J Epidemiol 2022 Aug 10;51(4):1204-1218. doi: 10.1093/ije/dyac025. PMID: 35218345Free PMC Article
Jiang H, Luo N, Zhang X, Song C, Zang J
Lung Cancer 2020 Jul;145:216-218. Epub 2020 Apr 15 doi: 10.1016/j.lungcan.2020.04.001. PMID: 32345450
Ang YL, Tan HL, Soo RA
Ther Adv Respir Dis 2015 Oct;9(5):224-35. Epub 2015 Apr 22 doi: 10.1177/1753465815581147. PMID: 25902866

Curated

UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023

Recent clinical studies

Etiology

Gorman BR, Ji SG, Francis M, Sendamarai AK, Shi Y, Devineni P, Saxena U, Partan E, DeVito AK, Byun J, Han Y, Xiao X, Sin DD, Timens W, Moser J, Muralidhar S, Ramoni R, Hung RJ, McKay JD, Bossé Y, Sun R, Amos CI; VA Million Veteran Program, Pyarajan S
Nat Commun 2024 Oct 4;15(1):8629. doi: 10.1038/s41467-024-52129-4. PMID: 39366959Free PMC Article
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article
Cheung AH, Tong JH, Chung LY, Chau SL, Ng CS, Wan IYP, To KF
Pathology 2020 Apr;52(3):323-328. Epub 2020 Feb 27 doi: 10.1016/j.pathol.2019.12.003. PMID: 32113673
Denisov EV, Schegoleva AA, Gervas PA, Ponomaryova AA, Tashireva LA, Boyarko VV, Bukreeva EB, Pankova OV, Perelmuter VM
Lung Cancer 2019 Sep;135:21-28. Epub 2019 Jul 5 doi: 10.1016/j.lungcan.2019.07.001. PMID: 31446997

Diagnosis

Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Arandes-Marcocci J, Iglesias-Sancho M, Setó-Torrent N, Fernández-Figueras MT
An Bras Dermatol 2020 Jan-Feb;95(1):67-70. Epub 2019 Dec 31 doi: 10.1016/j.abd.2019.05.004. PMID: 31952995Free PMC Article
Gomes R, Fernandes F, Luís F
Arch Bronconeumol 2015 Dec;51(12):654. Epub 2015 Jul 4 doi: 10.1016/j.arbres.2015.05.015. PMID: 26153562
Kathula SK, Thomas DE, Anstadt MP, Khan AU
J Clin Oncol 2011 Feb 1;29(4):e83-5. Epub 2010 Nov 22 doi: 10.1200/JCO.2010.31.4708. PMID: 21098328
Valdivielso M, Longo I, Suárez R, Huerta M, Lázaro P
J Eur Acad Dermatol Venereol 2005 May;19(3):340-4. doi: 10.1111/j.1468-3083.2005.01083.x. PMID: 15857461

Therapy

Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article
Ang YL, Tan HL, Soo RA
Ther Adv Respir Dis 2015 Oct;9(5):224-35. Epub 2015 Apr 22 doi: 10.1177/1753465815581147. PMID: 25902866
Kathula SK, Thomas DE, Anstadt MP, Khan AU
J Clin Oncol 2011 Feb 1;29(4):e83-5. Epub 2010 Nov 22 doi: 10.1200/JCO.2010.31.4708. PMID: 21098328
Allen TM
Trends Pharmacol Sci 1994 Jul;15(7):215-20. doi: 10.1016/0165-6147(94)90314-x. PMID: 7940982

Prognosis

Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Comandatore A, Franczak M, Smolenski RT, Morelli L, Peters GJ, Giovannetti E
Semin Cancer Biol 2022 Nov;86(Pt 2):93-100. Epub 2022 Sep 9 doi: 10.1016/j.semcancer.2022.09.001. PMID: 36096316
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article
Hoque R, DelRosso L
BMJ Case Rep 2014 Mar 25;2014 doi: 10.1136/bcr-2013-201571. PMID: 24667991Free PMC Article
Kathula SK, Thomas DE, Anstadt MP, Khan AU
J Clin Oncol 2011 Feb 1;29(4):e83-5. Epub 2010 Nov 22 doi: 10.1200/JCO.2010.31.4708. PMID: 21098328

Clinical prediction guides

Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Comandatore A, Franczak M, Smolenski RT, Morelli L, Peters GJ, Giovannetti E
Semin Cancer Biol 2022 Nov;86(Pt 2):93-100. Epub 2022 Sep 9 doi: 10.1016/j.semcancer.2022.09.001. PMID: 36096316
Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article
Cheung AH, Tong JH, Chung LY, Chau SL, Ng CS, Wan IYP, To KF
Pathology 2020 Apr;52(3):323-328. Epub 2020 Feb 27 doi: 10.1016/j.pathol.2019.12.003. PMID: 32113673
Kathula SK, Thomas DE, Anstadt MP, Khan AU
J Clin Oncol 2011 Feb 1;29(4):e83-5. Epub 2010 Nov 22 doi: 10.1200/JCO.2010.31.4708. PMID: 21098328

Recent systematic reviews

Pearson-Stuttard J, Papadimitriou N, Markozannes G, Cividini S, Kakourou A, Gill D, Rizos EC, Monori G, Ward HA, Kyrgiou M, Gunter MJ, Tsilidis KK
Cancer Epidemiol Biomarkers Prev 2021 Jun;30(6):1218-1228. Epub 2021 Mar 18 doi: 10.1158/1055-9965.EPI-20-1245. PMID: 33737302Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

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      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2023
      UK NICE guideline NG122, Lung cancer: diagnosis and management, 2023

    Consumer resources