U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Heart block

MedGen UID:
42363
•Concept ID:
C0018794
•
Disease or Syndrome; Finding
Synonyms: Block, Heart; Blocks, Heart; Heart Block; Heart Blocks
SNOMED CT: Heart block (233916004); HB - Heart block (233916004)
 
HPO: HP:0012722

Definition

Impaired conduction of cardiac impulse occurring anywhere along the conduction pathway. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHeart block

Conditions with this feature

Meier-Gorlin syndrome 7
MedGen UID:
934705
•Concept ID:
C4310738
•
Disease or Syndrome
Any Meier-Gorlin syndrome in which the cause of the disease is a mutation in the CDC45 gene.
See: Condition Record
Meier-Gorlin syndrome 7

Professional guidelines

PubMed

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
J Am Coll Cardiol 2019 Aug 20;74(7):e51-e156. Epub 2018 Nov 6 doi: 10.1016/j.jacc.2018.10.044. PMID: 30412709
HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis.
Birnie DH, Sauer WH, Bogun F, Cooper JM, Culver DA, Duvernoy CS, Judson MA, Kron J, Mehta D, Cosedis Nielsen J, Patel AR, Ohe T, Raatikainen P, Soejima K
Heart Rhythm 2014 Jul;11(7):1305-23. Epub 2014 May 9 doi: 10.1016/j.hrthm.2014.03.043. PMID: 24819193

Recent clinical studies

Etiology

Congenital Heart Block.
Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Congenital Heart Block.
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Fetal dysrhythmias.
Carvalho JS
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:28-41. Epub 2019 Jan 9 doi: 10.1016/j.bpobgyn.2019.01.002. PMID: 30738635
Cardiac manifestations of systemic lupus erythematosus.
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Neonatal lupus syndrome.
Olson NY, Lindsley CB
Am J Dis Child 1987 Aug;141(8):908-10. doi: 10.1001/archpedi.1987.04460080094037. PMID: 3307387

Diagnosis

Congenital Heart Block.
Steinberg L
Cardiol Clin 2023 Aug;41(3):399-410. doi: 10.1016/j.ccl.2023.03.002. PMID: 37321690
Congenital Heart Block.
Steinberg L
Card Electrophysiol Clin 2021 Dec;13(4):691-702. doi: 10.1016/j.ccep.2021.07.006. PMID: 34689896
Commentary.
Wener MH
Clin Chem 2014 Sep;60(9):1156-7. doi: 10.1373/clinchem.2014.224535. PMID: 25170166
Atrioventricular block revisited.
Barold SS
Compr Ther 2002 Spring;28(1):74-8. doi: 10.1007/s12019-002-0044-6. PMID: 11894446
Peri-infarction block.
GRANT RP
Prog Cardiovasc Dis 1959 Nov;2:237-47. doi: 10.1016/s0033-0620(59)80004-9. PMID: 13828979

Therapy

Electrocautery-Induced Complete Heart Block.
Alghanem H, Patoli D, Greenberg SB, Szokol JW, Silk VL
J Cardiothorac Vasc Anesth 2021 Jul;35(7):2230-2232. Epub 2020 Nov 10 doi: 10.1053/j.jvca.2020.11.018. PMID: 33268040
Beta-blockers for congestive heart failure in children.
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y
Cochrane Database Syst Rev 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. PMID: 32700759Free PMC Article
Hydroxychloroquine to Prevent Recurrent Congenital Heart Block in Fetuses of Anti-SSA/Ro-Positive Mothers.
Izmirly P, Kim M, Friedman DM, Costedoat-Chalumeau N, Clancy R, Copel JA, Phoon CKL, Cuneo BF, Cohen RE, Robins K, Masson M, Wainwright BJ, Zahr N, Saxena A, Buyon JP
J Am Coll Cardiol 2020 Jul 21;76(3):292-302. doi: 10.1016/j.jacc.2020.05.045. PMID: 32674792Free PMC Article
Fetal dysrhythmias.
Carvalho JS
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:28-41. Epub 2019 Jan 9 doi: 10.1016/j.bpobgyn.2019.01.002. PMID: 30738635
Mitral Annulus Calcium Score.
Brodov Y, Konen E, Di Segni M, Samoocha D, Chernomordik F, Barbash I, Regev E, Raanani E, Guetta V, Segev A, Fefer P, Glikson M, Goitein O
Circ Cardiovasc Imaging 2019 Dec;12(1):e007508. doi: 10.1161/CIRCIMAGING.117.007508. PMID: 30636515

Prognosis

Atrioventricular Dissociation during Ventricular Fibrillation.
Salik JR, Thomas SS
N Engl J Med 2020 Jun 4;382(23):e84. doi: 10.1056/NEJMicm1916823. PMID: 32492307
Congenitally corrected transposition.
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article
Wenckebach variant.
Karakozov M, Nikolić G
Heart Lung 2007 Jan-Feb;36(1):85-6. doi: 10.1016/j.hrtlng.2006.09.003. PMID: 17234482
Cough-induced heart block.
Lee D, Beldner S, Pollaro F, Jadonath R, Maccaro P, Goldner B
Pacing Clin Electrophysiol 1999 Aug;22(8):1270-1. doi: 10.1111/j.1540-8159.1999.tb00615.x. PMID: 10461310
Sinus node arrest and sino--atrial block.
Shaw DB, Southall DP
Eur Heart J 1984 Mar;5 Suppl A:83-7. doi: 10.1093/eurheartj/5.suppl_a.83. PMID: 6373289

Clinical prediction guides

Autoimmune-mediated congenital heart block.
Wainwright B, Bhan R, Trad C, Cohen R, Saxena A, Buyon J, Izmirly P
Best Pract Res Clin Obstet Gynaecol 2020 Apr;64:41-51. Epub 2019 Oct 8 doi: 10.1016/j.bpobgyn.2019.09.001. PMID: 31685414
Mitral Annulus Calcium Score.
Brodov Y, Konen E, Di Segni M, Samoocha D, Chernomordik F, Barbash I, Regev E, Raanani E, Guetta V, Segev A, Fefer P, Glikson M, Goitein O
Circ Cardiovasc Imaging 2019 Dec;12(1):e007508. doi: 10.1161/CIRCIMAGING.117.007508. PMID: 30636515
Tale of 2 Orifices.
Vainrib AF, Loulmet DF, Williams MR, Saric M
Circ Cardiovasc Imaging 2019 Dec;12(1):e008372. doi: 10.1161/CIRCIMAGING.118.008372. PMID: 30636514
Cardiac manifestations of systemic lupus erythematosus.
Miner JJ, Kim AH
Rheum Dis Clin North Am 2014 Feb;40(1):51-60. doi: 10.1016/j.rdc.2013.10.003. PMID: 24268009
Atrioventricular block.
Cross JA
AACN Clin Issues Crit Care Nurs 1992 Feb;3(1):166-72. doi: 10.4037/15597768-1992-1021. PMID: 1554557

Recent systematic reviews

Maternal and infant outcomes of pregnancy associated with anti-SSA/RO antibodies: a systematic review and meta-analysis.
Sheng X, Song X, Xiong Y, Ren T, Chang X, Wu J, Cao J, Cheng T, Wang M
Pediatr Rheumatol Online J 2023 Mar 4;21(1):22. doi: 10.1186/s12969-023-00803-0. PMID: 36870970Free PMC Article
BRASH Syndrome: A Systematic Review of Reported Cases.
Majeed H, Khan U, Khan AM, Khalid SN, Farook S, Gangu K, Sagheer S, Sheikh AB
Curr Probl Cardiol 2023 Jun;48(6):101663. Epub 2023 Feb 24 doi: 10.1016/j.cpcardiol.2023.101663. PMID: 36842470
Beta-blockers for congestive heart failure in children.
Alabed S, Sabouni A, Al Dakhoul S, Bdaiwi Y
Cochrane Database Syst Rev 2020 Jul 23;7(7):CD007037. doi: 10.1002/14651858.CD007037.pub4. PMID: 32700759Free PMC Article
Fluorinated steroids are not superior to any treatment to ameliorate the outcome of autoimmune mediated congenital heart block: a systematic review of the literature and meta-analysis.
Hoxha A, Mattia E, Zanetti A, Carrara G, Morel N, Costedoat-Chalumeau N, Brucato AL, Ruffatti A
Clin Exp Rheumatol 2020 Jul-Aug;38(4):783-791. Epub 2020 Jun 23 PMID: 32573408
Systematic review of cardiac electrical disease in Kearns-Sayre syndrome and mitochondrial cytopathy.
Kabunga P, Lau AK, Phan K, Puranik R, Liang C, Davis RL, Sue CM, Sy RW
Int J Cardiol 2015 Feb 15;181:303-10. Epub 2014 Dec 13 doi: 10.1016/j.ijcard.2014.12.038. PMID: 25540845

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • ClinVar
      Related medical variations
    • GTR
      Related information in GTR
    • GTR(Clinical)
      Clinical tests in GTR
    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...