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Breast pericanalicular fibroadenoma

MedGen UID:
90794
•Concept ID:
C0334497
•
Neoplastic Process
Synonyms: Breast Pericanalicular Fibroadenoma; breast pericanalicular fibroadenoma; Pericanalicular Breast Fibroadenoma; pericanalicular breast fibroadenoma; Pericanalicular Fibroadenoma; Pericanalicular fibroadenoma; pericanalicular fibroadenoma; pericanalicular fibroadenoma (morphologic abnormality); Pericanalicular Fibroadenoma of Breast; pericanalicular fibroadenoma of breast; Pericanalicular Fibroadenoma of the Breast; pericanalicular fibroadenoma of the breast
SNOMED CT: Pericanalicular fibroadenoma (41382006)
 
Monarch Initiative: MONDO:0002371

Definition

A morphologic variant of breast fibroadenoma without clinical significance. It is characterized by circumferential proliferation of stromal cells around the ducts. This results in the formation of rounded ductal-epithelial structures. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast pericanalicular fibroadenoma

Recent clinical studies

Etiology

Fibroepithelial Neoplasm with Hybrid Features of Benign Phyllodes Tumor, Juvenile Papillomatosis, and Juvenile Fibroadenoma: A Case Report.
Liu BL, Mehrotra M, Kowtha L, Guan M, Houldsworth J, Baskovich B, Harigopal M
Int J Surg Pathol 2025 Feb;33(1):220-228. Epub 2024 Jun 5 doi: 10.1177/10668969241256112. PMID: 38839253
Main Traits of Breast Fibroadenoma Among Adolescent Girls.
Sun C, Zhang W, Ma H, Han N, Qi M, Li D, Wang X, Wang X, Yang J
Cancer Biother Radiopharm 2020 May;35(4):271-276. Epub 2020 Apr 8 doi: 10.1089/cbr.2019.3209. PMID: 32267738
Ultrasonic elastography features of phyllodes tumors of the breast: a clinical research.
Li LJ, Zeng H, Ou B, Luo BM, Xiao XY, Zhong WJ, Zhao XB, Zhao ZZ, Yang HY, Zhi H
PLoS One 2014;9(1):e85257. Epub 2014 Jan 15 doi: 10.1371/journal.pone.0085257. PMID: 24454830Free PMC Article
Fine needle aspiration cytology of fibroadenoma with multinucleated stromal giant cells. A review of cases in a six-year period.
Ng WK
Acta Cytol 2002 May-Jun;46(3):535-9. doi: 10.1159/000326873. PMID: 12040649

Diagnosis

Fibroepithelial Neoplasm with Hybrid Features of Benign Phyllodes Tumor, Juvenile Papillomatosis, and Juvenile Fibroadenoma: A Case Report.
Liu BL, Mehrotra M, Kowtha L, Guan M, Houldsworth J, Baskovich B, Harigopal M
Int J Surg Pathol 2025 Feb;33(1):220-228. Epub 2024 Jun 5 doi: 10.1177/10668969241256112. PMID: 38839253
Fibroepithelial tumours of the breast-a review.
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197
Main Traits of Breast Fibroadenoma Among Adolescent Girls.
Sun C, Zhang W, Ma H, Han N, Qi M, Li D, Wang X, Wang X, Yang J
Cancer Biother Radiopharm 2020 May;35(4):271-276. Epub 2020 Apr 8 doi: 10.1089/cbr.2019.3209. PMID: 32267738
Ultrasonic elastography features of phyllodes tumors of the breast: a clinical research.
Li LJ, Zeng H, Ou B, Luo BM, Xiao XY, Zhong WJ, Zhao XB, Zhao ZZ, Yang HY, Zhi H
PLoS One 2014;9(1):e85257. Epub 2014 Jan 15 doi: 10.1371/journal.pone.0085257. PMID: 24454830Free PMC Article
Phyllodes tumors and fibroadenoma common beginning and different ending.
Oprić S, Oprić D, Gugić D, Granić M
Coll Antropol 2012 Mar;36(1):235-41. PMID: 22816226

Therapy

Fine needle aspiration cytology of fibroadenoma with multinucleated stromal giant cells. A review of cases in a six-year period.
Ng WK
Acta Cytol 2002 May-Jun;46(3):535-9. doi: 10.1159/000326873. PMID: 12040649

Prognosis

Fibroepithelial tumours of the breast-a review.
Lerwill MF, Lee AHS, Tan PH
Virchows Arch 2022 Jan;480(1):45-63. Epub 2021 Sep 10 doi: 10.1007/s00428-021-03175-6. PMID: 34505197

Clinical prediction guides

Variation in glycosaminoglycan components of breast tumors.
Takeuchi J, Sobue M, Sato E, Shamoto M, Miura K
Cancer Res 1976 Jul;36(7 PT 1):2133-9. PMID: 179697

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