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Breast sarcoma

MedGen UID:
87613
•Concept ID:
C0349667
•
Neoplastic Process
Synonyms: Breast Sarcoma; breast sarcoma; PBS; Sarcoma of breast; Sarcoma of Breast; sarcoma of breast; Sarcoma of the Breast; sarcoma of the breast
SNOMED CT: Sarcoma of breast (278050001)
 
Monarch Initiative: MONDO:0002490

Definition

A malignant mesenchymal neoplasm that arises from the breast. Representative examples include angiosarcoma, liposarcoma, leiomyosarcoma, rhabdomyosarcoma, and extraskeletal osteosarcoma. [from NCI]

Professional guidelines

PubMed

Clinical and Molecular Insights of Radiation-Induced Breast Sarcomas: Is There Hope on the Horizon for Effective Treatment of This Aggressive Disease?
Kokkali S, Moreno JD, Klijanienko J, Theocharis S
Int J Mol Sci 2022 Apr 8;23(8) doi: 10.3390/ijms23084125. PMID: 35456944Free PMC Article
Management of Breast Sarcoma.
Hsu C, McCloskey SA, Peddi PF
Surg Clin North Am 2016 Oct;96(5):1047-58. doi: 10.1016/j.suc.2016.05.004. PMID: 27542642
Primary female breast sarcoma: clinicopathological features, treatment and prognosis.
Yin M, Mackley HB, Drabick JJ, Harvey HA
Sci Rep 2016 Aug 11;6:31497. doi: 10.1038/srep31497. PMID: 27510467Free PMC Article

Recent clinical studies

Etiology

Phyllodes tumours of the breast: a consensus review.
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, Calvo JP, Dabbs DJ, Ellis IO, Eusebi V, Farshid G, Fox SB, Ichihara S, Lakhani SR, Rakha EA, Reis-Filho JS, Richardson AL, Sahin A, Schmitt FC, Schnitt SJ, Siziopikou KP, Soares FA, Tse GM, Vincent-Salomon A, Tan PH
Histopathology 2016 Jan;68(1):5-21. doi: 10.1111/his.12876. PMID: 26768026Free PMC Article
Sarcoma of the breast: an update on a rare entity.
Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013
Sarcomas of the breast.
Lahat G, Lev D, Gerstenhaber F, Madewell J, Le-Petross H, Pollock RE
Expert Rev Anticancer Ther 2012 Aug;12(8):1045-51. doi: 10.1586/era.12.82. PMID: 23030224
Radiation-induced breast sarcoma.
Blanchard DK, Reynolds C, Grant CS, Farley DR, Donohue JH
Am J Surg 2002 Oct;184(4):356-8. doi: 10.1016/s0002-9610(02)00943-1. PMID: 12383902
Sarcoma of the breast.
Gogas JG, Kotsianos G, Gogas KG
Am Surg 1976 Nov;42(11):812-6. PMID: 185930

Diagnosis

Sarcomas of the Breast.
Duncan MA, Lautner MA
Surg Clin North Am 2018 Aug;98(4):869-876. Epub 2018 May 21 doi: 10.1016/j.suc.2018.03.013. PMID: 30005780
Phyllodes tumours of the breast: a consensus review.
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, Calvo JP, Dabbs DJ, Ellis IO, Eusebi V, Farshid G, Fox SB, Ichihara S, Lakhani SR, Rakha EA, Reis-Filho JS, Richardson AL, Sahin A, Schmitt FC, Schnitt SJ, Siziopikou KP, Soares FA, Tse GM, Vincent-Salomon A, Tan PH
Histopathology 2016 Jan;68(1):5-21. doi: 10.1111/his.12876. PMID: 26768026Free PMC Article
Sarcoma of the breast: an update on a rare entity.
Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013
Sarcomas of the breast.
Lahat G, Lev D, Gerstenhaber F, Madewell J, Le-Petross H, Pollock RE
Expert Rev Anticancer Ther 2012 Aug;12(8):1045-51. doi: 10.1586/era.12.82. PMID: 23030224
Primary breast sarcoma.
Lum YW, Jacobs L
Surg Clin North Am 2008 Jun;88(3):559-70, vi. doi: 10.1016/j.suc.2008.03.009. PMID: 18514698

Therapy

Reconstruction options and outcomes for breast sarcoma patients.
Carl HM, Calotta NA, Siotos C, Bos TJ, Foster DG III,, Manahan MA, Cooney CM, Sacks JM, Rosson GD
Breast J 2019 Jul;25(4):702-705. Epub 2019 Apr 25 doi: 10.1111/tbj.13243. PMID: 31025484
Sarcoma of the breast: an update on a rare entity.
Lim SZ, Ong KW, Tan BK, Selvarajan S, Tan PH
J Clin Pathol 2016 May;69(5):373-81. Epub 2016 Jan 4 doi: 10.1136/jclinpath-2015-203545. PMID: 26729013
Sarcomas of the breast.
Lahat G, Lev D, Gerstenhaber F, Madewell J, Le-Petross H, Pollock RE
Expert Rev Anticancer Ther 2012 Aug;12(8):1045-51. doi: 10.1586/era.12.82. PMID: 23030224
A rare case of breast sarcoma brain metastases.
Esquerdo G, Llorca C, Cervera JM, Briceño H
J Neurooncol 2005 Apr;72(2):123. doi: 10.1007/s11060-004-4594-6. PMID: 15925991
Radiation-induced breast sarcoma.
Blanchard DK, Reynolds C, Grant CS, Farley DR, Donohue JH
Am J Surg 2002 Oct;184(4):356-8. doi: 10.1016/s0002-9610(02)00943-1. PMID: 12383902

Prognosis

Sarcomas of the Breast.
Duncan MA, Lautner MA
Surg Clin North Am 2018 Aug;98(4):869-876. Epub 2018 May 21 doi: 10.1016/j.suc.2018.03.013. PMID: 30005780
Phyllodes tumours of the breast: a consensus review.
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, Calvo JP, Dabbs DJ, Ellis IO, Eusebi V, Farshid G, Fox SB, Ichihara S, Lakhani SR, Rakha EA, Reis-Filho JS, Richardson AL, Sahin A, Schmitt FC, Schnitt SJ, Siziopikou KP, Soares FA, Tse GM, Vincent-Salomon A, Tan PH
Histopathology 2016 Jan;68(1):5-21. doi: 10.1111/his.12876. PMID: 26768026Free PMC Article
Sarcomas of the breast.
Lahat G, Lev D, Gerstenhaber F, Madewell J, Le-Petross H, Pollock RE
Expert Rev Anticancer Ther 2012 Aug;12(8):1045-51. doi: 10.1586/era.12.82. PMID: 23030224
Primary breast sarcoma.
Lum YW, Jacobs L
Surg Clin North Am 2008 Jun;88(3):559-70, vi. doi: 10.1016/j.suc.2008.03.009. PMID: 18514698
Breast sarcoma.
Moore MP, Kinne DW
Surg Clin North Am 1996 Apr;76(2):383-92. doi: 10.1016/s0039-6109(05)70445-x. PMID: 8610270

Clinical prediction guides

Total autologous breast reconstruction with the Kiss Latissimus Dorsi Flap.
Brunetti B, Salzillo R, Tenna S, Cagli B, Coppola M M, Petrucci V, Camilloni C, Zhang YX, Persichetti P
J Plast Reconstr Aesthet Surg 2022 Oct;75(10):3673-3682. Epub 2022 Jun 28 doi: 10.1016/j.bjps.2022.06.078. PMID: 36055926
Primary and Secondary Breast Sarcoma: Clinical and Pathological Characteristics, Prognostic Factors, and Nomograms for Predicting Survival.
Osman MH, Rabie NA, Elmehrath AO, Bedair HM, Fala SY, Ghaith HS, Refaat MA
Clin Breast Cancer 2022 Oct;22(7):e753-e763. Epub 2022 Jul 23 doi: 10.1016/j.clbc.2022.07.006. PMID: 35963779
Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study.
Karlsson F, Granath F, Smedby KE, Zedenius J, Bränström R, Nilsson IL
Breast Cancer Res Treat 2020 Oct;183(3):669-675. Epub 2020 Jul 21 doi: 10.1007/s10549-020-05802-3. PMID: 32696318Free PMC Article
Phyllodes tumours of the breast: a consensus review.
Tan BY, Acs G, Apple SK, Badve S, Bleiweiss IJ, Brogi E, Calvo JP, Dabbs DJ, Ellis IO, Eusebi V, Farshid G, Fox SB, Ichihara S, Lakhani SR, Rakha EA, Reis-Filho JS, Richardson AL, Sahin A, Schmitt FC, Schnitt SJ, Siziopikou KP, Soares FA, Tse GM, Vincent-Salomon A, Tan PH
Histopathology 2016 Jan;68(1):5-21. doi: 10.1111/his.12876. PMID: 26768026Free PMC Article
Comparison of the clinical and prognostic features of primary breast sarcomas and malignant phyllodes tumor.
Wang F, Jia Y, Tong Z
Jpn J Clin Oncol 2015 Feb;45(2):146-52. Epub 2014 Nov 11 doi: 10.1093/jjco/hyu177. PMID: 25387733

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