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Breast Neoplasms, Male

MedGen UID:
66983
Concept ID:
C0242788
Neoplastic Process
Synonyms: Breast Neoplasm, Male; Breast Tumor, Male; Breast Tumors, Male; Male Breast Neoplasm; Male Breast Neoplasms; Male Breast Tumor; Male Breast Tumors; Neoplasm, Male Breast; Neoplasms, Breast, Male; Neoplasms, Male Breast; Tumor, Male Breast; Tumors, Breast, Male; Tumors, Male Breast

Definition

Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Neoplasms, Male

Professional guidelines

PubMed

Makdissi FBA, Santos SS, Bitencourt A, Campos FAB
Int Braz J Urol 2022 Sep-Oct;48(5):760-770. doi: 10.1590/S1677-5538.IBJU.2021.0828. PMID: 35373955Free PMC Article
Johnson AE, Coopey SB, Spring LM, Horick NK, Leone JP, Lin NU, Dominici LS, Hughes KS, Jimenez RB
Breast Cancer Res Treat 2021 Jul;188(2):561-569. Epub 2021 Apr 8 doi: 10.1007/s10549-021-06174-y. PMID: 33830393
Meijer M, Thygesen LC, Green A, Emneus M, Brasso K, Iversen P, Pukkala E, Bolin K, Stavem K, Ersbøll AK
Cancer Med 2018 Jan;7(1):254-260. Epub 2017 Dec 13 doi: 10.1002/cam4.1273. PMID: 29239131Free PMC Article

Recent clinical studies

Etiology

Bhardwaj PV, Gupta S, Elyash A, Teplinsky E
Curr Oncol Rep 2024 Jan;26(1):34-45. Epub 2024 Jan 2 doi: 10.1007/s11912-023-01489-z. PMID: 38224426
Fox S, Speirs V, Shaaban AM
Virchows Arch 2022 Jan;480(1):85-93. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03190-7. PMID: 34458944
Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F
Breast Cancer Res Treat 2019 Jan;173(1):37-48. Epub 2018 Sep 28 doi: 10.1007/s10549-018-4921-9. PMID: 30267249Free PMC Article
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847
Abdelwahab Yousef AJ
Semin Oncol 2017 Aug;44(4):267-272. Epub 2017 Nov 9 doi: 10.1053/j.seminoncol.2017.11.002. PMID: 29526255

Diagnosis

AlFehaid M
Pol Przegl Chir 2023 Dec 30;95(6):24-30. PMID: 38058163
Lin AP, Huang TW, Tam KW
Br J Surg 2021 Sep 27;108(9):1034-1042. doi: 10.1093/bjs/znab279. PMID: 34476472
Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Aug 1;30(8):1194-1220. doi: 10.1093/annonc/mdz173. PMID: 31161190
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944

Therapy

Turner NC, Im SA, Saura C, Juric D, Loibl S, Kalinsky K, Schmid P, Loi S, Sunpaweravong P, Musolino A, Li H, Zhang Q, Nowecki Z, Leung R, Thanopoulou E, Shankar N, Lei G, Stout TJ, Hutchinson KE, Schutzman JL, Song C, Jhaveri KL
N Engl J Med 2024 Oct 31;391(17):1584-1596. doi: 10.1056/NEJMoa2404625. PMID: 39476340
AlFehaid M
Pol Przegl Chir 2023 Dec 30;95(6):24-30. PMID: 38058163
Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F
Breast Cancer Res Treat 2019 Jan;173(1):37-48. Epub 2018 Sep 28 doi: 10.1007/s10549-018-4921-9. PMID: 30267249Free PMC Article
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847
Wibowo E, Pollock PA, Hollis N, Wassersug RJ
Andrology 2016 Sep;4(5):776-88. Epub 2016 May 6 doi: 10.1111/andr.12197. PMID: 27152880

Prognosis

Pullen RL Jr
Nursing 2025 Mar 1;55(3):18-26. Epub 2025 Feb 21 doi: 10.1097/NSG.0000000000000146. PMID: 39980112
Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Aug 1;30(8):1194-1220. doi: 10.1093/annonc/mdz173. PMID: 31161190
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944
Malani AK
South Med J 2007 Feb;100(2):197. doi: 10.1097/01.smj.0000209277.21066.c2. PMID: 17330691
Loerzel VW, Dow KH
Clin J Oncol Nurs 2004 Apr;8(2):191-2. doi: 10.1188/04.CJON.191-192. PMID: 15108421

Clinical prediction guides

Fentiman IS
Breast J 2021 Dec;27(12):877-882. Epub 2021 Oct 15 doi: 10.1111/tbj.14297. PMID: 34652050
Khan NAJ, Tirona M
Med Oncol 2021 Mar 15;38(4):39. doi: 10.1007/s12032-021-01486-x. PMID: 33721121
Hassett MJ, Somerfield MR, Baker ER, Cardoso F, Kansal KJ, Kwait DC, Plichta JK, Ricker C, Roshal A, Ruddy KJ, Safer JD, Van Poznak C, Yung RL, Giordano SH
J Clin Oncol 2020 Jun 1;38(16):1849-1863. Epub 2020 Feb 14 doi: 10.1200/JCO.19.03120. PMID: 32058842
Narula HS, Carlson HE
Endocrinol Metab Clin North Am 2007 Jun;36(2):497-519. doi: 10.1016/j.ecl.2007.03.013. PMID: 17543732
Ahmed R, Ali SM
J Coll Physicians Surg Pak 2005 Apr;15(4):238-41. PMID: 15857599

Recent systematic reviews

Deldar R, Sayyed AA, Towfighi P, Aminpour N, Sogunro O, Son JD, Fan KL, Song DH
Breast J 2022;2022:5482261. Epub 2022 Mar 29 doi: 10.1155/2022/5482261. PMID: 35711890Free PMC Article
Wang Y, Reulen RC, Kremer LCM, de Vathaire F, Haupt R, Zadravec Zaletel L, Bagnasco F, Demoor-Goldschmidt C, van Dorp WJ, Haddy N, Hjorth L, Jakab Z, Kuehni CE, Lähteenmäki PM, van der Pal HJH, Sacerdote C, Skinner R, Terenziani M, Wesenberg F, Winther JF, van Leeuwen FE, Hawkins MM, Teepen JC, van Dalen EC, Ronckers CM
Eur J Cancer 2022 Apr;165:27-47. Epub 2022 Feb 21 doi: 10.1016/j.ejca.2022.01.001. PMID: 35202973
Chamseddine RS, Wang C, Yin K, Wang J, Singh P, Zhou J, Robson ME, Braun D, Hughes KS
Breast Cancer Res Treat 2022 Jan;191(1):31-38. Epub 2021 Oct 13 doi: 10.1007/s10549-021-06413-2. PMID: 34642874
Hassett MJ, Somerfield MR, Baker ER, Cardoso F, Kansal KJ, Kwait DC, Plichta JK, Ricker C, Roshal A, Ruddy KJ, Safer JD, Van Poznak C, Yung RL, Giordano SH
J Clin Oncol 2020 Jun 1;38(16):1849-1863. Epub 2020 Feb 14 doi: 10.1200/JCO.19.03120. PMID: 32058842
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944

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