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Hemoglobin H disease, nondeletional

MedGen UID:
481191
Concept ID:
C3279561
Disease or Syndrome
Synonym: Hemoglobin Pakse
 
OMIM®: 141800; 141850; 613978

Professional guidelines

PubMed

Kemper AR, Knapp AA, Metterville DR, Comeau AM, Green NS, Perrin JM
J Pediatr 2011 May;158(5):780-3. Epub 2010 Dec 16 doi: 10.1016/j.jpeds.2010.10.042. PMID: 21167500

Recent clinical studies

Etiology

Abolghasemi H, Kamfar S, Azarkeivan A, Karimi M, Keikhaei B, Abolghasemi F, Radfar MH, Eshghi P, Alavi S
Pediatr Hematol Oncol 2022 Sep;39(6):489-499. Epub 2021 Dec 24 doi: 10.1080/08880018.2021.2017529. PMID: 34951342
Adekile A, Sukumaran J, Thomas D, D'Souza T, Haider M
BMC Med Genet 2020 Aug 24;21(1):170. doi: 10.1186/s12881-020-01105-y. PMID: 32831051Free PMC Article
Vichinsky EP
Cold Spring Harb Perspect Med 2013 May 1;3(5):a011742. doi: 10.1101/cshperspect.a011742. PMID: 23543077Free PMC Article
Mach-Pascual S, Darbellay R, Pilotto PA, Beris P
Eur J Haematol 1996 Jul;57(1):54-61. doi: 10.1111/j.1600-0609.1996.tb00490.x. PMID: 8698132
Peres MJ, Romão L, Carreiro H, Picanço I, Batalha L, Magalhães HA, Martins MC, Lavinha J
Hemoglobin 1995;19(6):343-52. doi: 10.3109/03630269509005826. PMID: 8718693

Diagnosis

Abolghasemi H, Kamfar S, Azarkeivan A, Karimi M, Keikhaei B, Abolghasemi F, Radfar MH, Eshghi P, Alavi S
Pediatr Hematol Oncol 2022 Sep;39(6):489-499. Epub 2021 Dec 24 doi: 10.1080/08880018.2021.2017529. PMID: 34951342
Farashi S, Vakili S, Garous NF, Ashki M, Imanian H, Azarkeivan A, Najmabadi H
Hemoglobin 2015;39(6):398-402. Epub 2015 Sep 2 doi: 10.3109/03630269.2015.1075890. PMID: 26329872
Vichinsky EP
Cold Spring Harb Perspect Med 2013 May 1;3(5):a011742. doi: 10.1101/cshperspect.a011742. PMID: 23543077Free PMC Article
Chan V, Chan VW, Tang M, Lau K, Todd D, Chan TK
Br J Haematol 1997 Feb;96(2):224-8. doi: 10.1046/j.1365-2141.1997.d01-2017.x. PMID: 9029003
Embury SH
Hemoglobin 1988;12(5-6):445-53. doi: 10.3109/03630268808991633. PMID: 3061977

Therapy

Chappell ME, Breda L, Tricoli L, Guerra A, Jarocha D, Castruccio Castracani C, Papp TE, Tanaka N, Hamilton N, Triebwasser MP, Ghiaccio V, Fedorky MT, Gollomp KL, Bochenek V, Roche AM, Everett JK, Cook EJ, Bushman FD, Teawtrakul N, Glentis S, Kattamis A, Mui BL, Tam YK, Weissman D, Abdulmalik O, Parhiz H, Rivella S
Blood 2024 Oct 10;144(15):1633-1645. doi: 10.1182/blood.2023023349. PMID: 38949981Free PMC Article
Qin J, He J, Li Y, Liu N, Tao F, Zhang P, Guo W, Qin Q, Zhou W
J Clin Pathol 2023 Sep;76(9):632-636. Epub 2022 Jun 14 doi: 10.1136/jclinpath-2022-208363. PMID: 35701141
Sirivadhanakul P, Chuansumrit A, Songdej D, Kadegasem P, Wongwerawattanakoon P, Sirachainan N
Ann Hematol 2019 Jul;98(7):1593-1602. Epub 2019 Apr 5 doi: 10.1007/s00277-019-03672-4. PMID: 30953084
Fucharoen S, Viprakasit V
Hematology Am Soc Hematol Educ Program 2009:26-34. doi: 10.1182/asheducation-2009.1.26. PMID: 20008179
Harteveld CL, Yavarian M, Zorai A, Quakkelaar ED, van Delft P, Giordano PC
Am J Hematol 2003 Oct;74(2):99-103. doi: 10.1002/ajh.10385. PMID: 14508795

Prognosis

Ropero P, González FA, Nieto JM, Villegas A, Sevilla J, Pérez G, Alonso JM, Recasens V, Abio M, Vagace JM, Vanegas RJ, González Fernández B, Martínez R
J Clin Pathol 2020 Jan;73(1):14-16. Epub 2019 Aug 21 doi: 10.1136/jclinpath-2019-206004. PMID: 31434698
Vichinsky EP
Cold Spring Harb Perspect Med 2013 May 1;3(5):a011742. doi: 10.1101/cshperspect.a011742. PMID: 23543077Free PMC Article
Kemper AR, Knapp AA, Metterville DR, Comeau AM, Green NS, Perrin JM
J Pediatr 2011 May;158(5):780-3. Epub 2010 Dec 16 doi: 10.1016/j.jpeds.2010.10.042. PMID: 21167500
Fucharoen S, Viprakasit V
Hematology Am Soc Hematol Educ Program 2009:26-34. doi: 10.1182/asheducation-2009.1.26. PMID: 20008179
Peres MJ, Romão L, Carreiro H, Picanço I, Batalha L, Magalhães HA, Martins MC, Lavinha J
Hemoglobin 1995;19(6):343-52. doi: 10.3109/03630269509005826. PMID: 8718693

Clinical prediction guides

Wiromrat P, Rattanathongkom A, Laoaroon N, Suwannaying K, Komwilaisak P, Panamonta O, Wongsurawat N, Nasomyont N
J Clin Densitom 2023 Jul-Sep;26(3):101379. Epub 2023 Apr 26 doi: 10.1016/j.jocd.2023.101379. PMID: 37147222
Farashi S, Vakili S, Garous NF, Ashki M, Imanian H, Azarkeivan A, Najmabadi H
Hemoglobin 2015;39(6):398-402. Epub 2015 Sep 2 doi: 10.3109/03630269.2015.1075890. PMID: 26329872
Chao YH, Wu KH, Wu HP, Liu SC, Peng CT, Lee MS
Biomed Res Int 2014;2014:271070. Epub 2014 Aug 28 doi: 10.1155/2014/271070. PMID: 25309906Free PMC Article
Turbpaiboon C, Siritantikorn A, Thongnoppakhun W, Bunditworapoom D, Limwongse C, Yenchitsomanus PT, Siritanaratkul N, Wilairat P
Int J Hematol 2004 Aug;80(2):136-9. doi: 10.1532/ijh97.a20402. PMID: 15481441
Fisher CA, Premawardhena A, de Silva S, Perera G, Rajapaksa S, Olivieri NA, Old JM, Weatherall DJ; Sri Lanka Thalassaemia Study Group
Br J Haematol 2003 May;121(4):662-71. doi: 10.1046/j.1365-2141.2003.04346.x. PMID: 12752111

Recent systematic reviews

Kemper AR, Knapp AA, Metterville DR, Comeau AM, Green NS, Perrin JM
J Pediatr 2011 May;158(5):780-3. Epub 2010 Dec 16 doi: 10.1016/j.jpeds.2010.10.042. PMID: 21167500

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