U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Body ache

MedGen UID:
1708321
•Concept ID:
C0741585
•
Sign or Symptom
HPO: HP:0033047

Definition

Body ache is a complaint that is often used to denote vague symptoms of mild fatigue, lethargy, or dull aches. We will define it here to mean a dull and poorly localizable pain that is described by the affected individual to affect multiple joints or body parts or even the entire body. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBody ache

Conditions with this feature

Werner syndrome
MedGen UID:
12147
•Concept ID:
C0043119
•
Disease or Syndrome
Werner syndrome is characterized by the premature appearance of features associated with normal aging and cancer predisposition. Individuals with Werner syndrome develop normally until the end of the first decade. The first sign is the lack of a growth spurt during the early teen years. Early findings (usually observed in the 20s) include loss and graying of hair, hoarseness, and scleroderma-like skin changes, followed by bilateral ocular cataracts, type 2 diabetes mellitus, hypogonadism, skin ulcers, and osteoporosis in the 30s. Myocardial infarction and cancer are the most common causes of death; the mean age of death in individuals with Werner syndrome is 54 years.
See: Condition Record
Werner syndrome

Professional guidelines

PubMed

Real-world analysis of safety, tolerability, and adherence to nirmatrelvir-ritonavir (paxlovid) in primary care COVID-19 outpatients.
Zaharuddin Z, Md Hussin NS, Karuppannan M
Sci Rep 2024 Oct 21;14(1):24750. doi: 10.1038/s41598-024-75192-9. PMID: 39433826Free PMC Article
Kratom Dependence and Treatment Options: A Comprehensive Review of the Literature.
Bin Abdullah MFIL
Curr Drug Targets 2020;21(15):1566-1579. doi: 10.2174/1389450121666200719011653. PMID: 32682371
Clozapine for treatment-resistant bipolar disorder: a systematic review.
Li XB, Tang YL, Wang CY, de Leon J
Bipolar Disord 2015 May;17(3):235-47. Epub 2014 Oct 27 doi: 10.1111/bdi.12272. PMID: 25346322

Recent clinical studies

Etiology

Dengue Cases Presenting to the Emergency Department of a Tertiary Care Hospital in Late 2021: A Cross-Sectional Study in Karachi.
Mushtaq S, Abro MT, Hussain HU
Int J Public Health 2024;69:1606753. Epub 2024 Feb 15 doi: 10.3389/ijph.2024.1606753. PMID: 38426186Free PMC Article
COVID-19 vaccination in people with multiple sclerosis, real-life experience.
Alroughani R, Al-Hashel J, Abokalawa F, AlMojel M, Farouk Ahmed S
Clin Neurol Neurosurg 2022 Sep;220:107374. Epub 2022 Jul 19 doi: 10.1016/j.clineuro.2022.107374. PMID: 35961255Free PMC Article
COVID-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods.
Marofi F, Azizi R, Motavalli R, Vahedi G, Nasimi M, Yousefi M, Motavalli Y, Tahmasebi S, Gharibi T, Mohammed RN, Etemadi J, Khiavi FM
Anticancer Agents Med Chem 2021 Oct 28;21(16):2142-2162. doi: 10.2174/1871520621666210201101245. PMID: 33563186
Early recovery patterns of olfactory disorders in COVID-19 patients; a clinical cohort study.
Amer MA, Elsherif HS, Abdel-Hamid AS, Elzayat S
Am J Otolaryngol 2020 Nov-Dec;41(6):102725. Epub 2020 Sep 14 doi: 10.1016/j.amjoto.2020.102725. PMID: 32979666Free PMC Article
Dengue encephalitis: why we need to identify this entity in a dengue-prone region.
Muzaffar J, Venkata Krishnan P, Gupta N, Kar P
Singapore Med J 2006 Nov;47(11):975-7. PMID: 17075667

Diagnosis

Applying symptom dynamics to accurately predict influenza virus infection: An international multicenter influenza-like illness surveillance study.
Li JH, Wu CC, Tseng YJ, Han ST, Pekosz A, Rothman R, Chen KF
Influenza Other Respir Viruses 2023 Jan;17(1):e13081. Epub 2022 Dec 8 doi: 10.1111/irv.13081. PMID: 36480419Free PMC Article
Should COVID-19 symptoms be used to cohort patients in the emergency department? A retrospective analysis.
Bijur PE, Friedman BW, Baron SW, Ramasahayam A, Nerenberg R, Sharpe S, Goldstein DY, Esses D
Am J Emerg Med 2022 Apr;54:274-278. Epub 2022 Feb 6 doi: 10.1016/j.ajem.2022.01.070. PMID: 35220142Free PMC Article
COVID-19: Our Current Knowledge of Epidemiology, Pathology, Therapeutic Approaches, and Diagnostic Methods.
Marofi F, Azizi R, Motavalli R, Vahedi G, Nasimi M, Yousefi M, Motavalli Y, Tahmasebi S, Gharibi T, Mohammed RN, Etemadi J, Khiavi FM
Anticancer Agents Med Chem 2021 Oct 28;21(16):2142-2162. doi: 10.2174/1871520621666210201101245. PMID: 33563186
Tobacco Use and Orofacial Pain: A Meta-analysis.
Alamir AH, Quadri MFA
Nicotine Tob Res 2020 Oct 29;22(11):1957-1963. doi: 10.1093/ntr/ntaa074. PMID: 32374841
Dengue encephalitis: why we need to identify this entity in a dengue-prone region.
Muzaffar J, Venkata Krishnan P, Gupta N, Kar P
Singapore Med J 2006 Nov;47(11):975-7. PMID: 17075667

Therapy

COVID-19 Vaccination Program for Children: An Electronic Assessment of Symptoms.
Kumar N, Khora A, Loomba R, Sharma N, Kumar A, Rana A, Kamboj R, Kamboj S, Guarve K, Guatam SP
Curr Drug Saf 2024;19(1):96-105. doi: 10.2174/1574886318666230331085630. PMID: 36999717
Kratom Dependence and Treatment Options: A Comprehensive Review of the Literature.
Bin Abdullah MFIL
Curr Drug Targets 2020;21(15):1566-1579. doi: 10.2174/1389450121666200719011653. PMID: 32682371
A young woman with oligomenorrohea and dysphagia.
Singha A, Biswas D, Patil M
Eur J Intern Med 2017 Jan;37:e7-e8. Epub 2016 Aug 20 doi: 10.1016/j.ejim.2016.08.009. PMID: 27553698
Clozapine for treatment-resistant bipolar disorder: a systematic review.
Li XB, Tang YL, Wang CY, de Leon J
Bipolar Disord 2015 May;17(3):235-47. Epub 2014 Oct 27 doi: 10.1111/bdi.12272. PMID: 25346322
Efficacy of Lianhuaqingwen capsule compared with oseltamivir for influenza A virus infection: a meta-analysis of randomized, controlled trials.
Zhao P, Yang HZ, Lv HY, Wei ZM
Altern Ther Health Med 2014 Mar-Apr;20(2):25-30. PMID: 24657957

Prognosis

Persistent COVID-19 symptoms at least one month after diagnosis: A national survey.
Tleyjeh IM, Kashour T, Riaz M, Amer SA, AlSwaidan N, Almutairi L, Halwani R, Assiri A
J Infect Public Health 2022 May;15(5):578-585. Epub 2022 Apr 20 doi: 10.1016/j.jiph.2022.04.006. PMID: 35477145Free PMC Article
Should COVID-19 symptoms be used to cohort patients in the emergency department? A retrospective analysis.
Bijur PE, Friedman BW, Baron SW, Ramasahayam A, Nerenberg R, Sharpe S, Goldstein DY, Esses D
Am J Emerg Med 2022 Apr;54:274-278. Epub 2022 Feb 6 doi: 10.1016/j.ajem.2022.01.070. PMID: 35220142Free PMC Article
Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial).
Shaikh N, Khatib MY, Wraidat MAA, Mohamed AS, Al-Assaf AA, Tharayil AGM, Abujaber AA, Nashwan AJ
Medicine (Baltimore) 2022 Jan 28;101(4):e28637. doi: 10.1097/MD.0000000000028637. PMID: 35089202Free PMC Article
Early recovery patterns of olfactory disorders in COVID-19 patients; a clinical cohort study.
Amer MA, Elsherif HS, Abdel-Hamid AS, Elzayat S
Am J Otolaryngol 2020 Nov-Dec;41(6):102725. Epub 2020 Sep 14 doi: 10.1016/j.amjoto.2020.102725. PMID: 32979666Free PMC Article
Tobacco Use and Orofacial Pain: A Meta-analysis.
Alamir AH, Quadri MFA
Nicotine Tob Res 2020 Oct 29;22(11):1957-1963. doi: 10.1093/ntr/ntaa074. PMID: 32374841

Clinical prediction guides

Clinical and hematological profiles of children with dengue residing in a non-endemic zone of Bangladesh.
Islam S, Khan MAS, Badal MFA, Khan MZI, Gozal D, Hasan MJ
PLoS Negl Trop Dis 2022 Oct;16(10):e0010847. Epub 2022 Oct 10 doi: 10.1371/journal.pntd.0010847. PMID: 36215330Free PMC Article
Adverse Events Following COVID-19 Vaccination in Rivers State, Nigeria: A Cross-Sectional Study.
Harry AM, Edet CK, Ekanem NE, Kemdirim CJ, Uduak AE
Niger Postgrad Med J 2022 Apr-Jun;29(2):89-95. doi: 10.4103/npmj.npmj_11_22. PMID: 35488575
Persistent COVID-19 symptoms at least one month after diagnosis: A national survey.
Tleyjeh IM, Kashour T, Riaz M, Amer SA, AlSwaidan N, Almutairi L, Halwani R, Assiri A
J Infect Public Health 2022 May;15(5):578-585. Epub 2022 Apr 20 doi: 10.1016/j.jiph.2022.04.006. PMID: 35477145Free PMC Article
Omicron SARS-CoV-2 new variant: global prevalence and biological and clinical characteristics.
Meo SA, Meo AS, Al-Jassir FF, Klonoff DC
Eur Rev Med Pharmacol Sci 2021 Dec;25(24):8012-8018. doi: 10.26355/eurrev_202112_27652. PMID: 34982465
An outbreak of Japanese encephalitis after two decades in Odisha, India.
Dwibedi B, Mohapatra N, Rathore SK, Panda M, Pati SS, Sabat J, Thakur B, Panda S, Kar SK
Indian J Med Res 2015 Dec;142 Suppl(Suppl 1):S30-2. doi: 10.4103/0971-5916.176609. PMID: 26905239Free PMC Article

Recent systematic reviews

New variants of COVID-19 (XBB.1.5 and XBB.1.16, the "Arcturus"): A review of highly questioned concerns, a brief comparison between different peaks in the COVID-19 pandemic, with a focused systematic review on expert recommendations for prevention, vaccination, and treatment measures in the general population and at-risk groups.
Pourriyahi H, Hajizadeh N, Khosravi M, Pourriahi H, Soleimani S, Hosseini NS, Mohammad AP, Goodarzi A
Immun Inflamm Dis 2024 Jun;12(6):e1323. doi: 10.1002/iid3.1323. PMID: 38938013Free PMC Article
Clozapine for treatment-resistant bipolar disorder: a systematic review.
Li XB, Tang YL, Wang CY, de Leon J
Bipolar Disord 2015 May;17(3):235-47. Epub 2014 Oct 27 doi: 10.1111/bdi.12272. PMID: 25346322

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...