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Unresectable Breast Carcinoma

MedGen UID:
1702294
Concept ID:
C5203936
Neoplastic Process

Definition

Breast carcinoma that is not amenable to surgical resection. [from NCI]

Professional guidelines

PubMed

Pierre ME, Manneh R, Hernández A, Rodríguez J, Fletcher AV, Ramírez HM, Niño OM, Gómez DA, Sanabria D, Contreras F, Pieschacón JR, Calderón PH
Rev Colomb Obstet Ginecol 2024 Jun 14;75(1) doi: 10.18597/rcog.4094. PMID: 39013199Free PMC Article
Rugo HS, Bianchini G, Cortes J, Henning JW, Untch M
ESMO Open 2022 Aug;7(4):100553. Epub 2022 Aug 11 doi: 10.1016/j.esmoop.2022.100553. PMID: 35964548Free PMC Article
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393

Recent clinical studies

Etiology

André F, Hee Park Y, Kim SB, Takano T, Im SA, Borges G, Lima JP, Aksoy S, Gavila Gregori J, De Laurentiis M, Bianchini G, Roylance R, Miyoshi Y, Armstrong A, Sinha R, Ruiz Borrego M, Lim E, Ettl J, Yerushalmi R, Zagouri F, Duhoux FP, Fehm T, Gambhire D, Cathcart J, Wu C, Chu C, Egorov A, Krop I
Lancet 2023 May 27;401(10390):1773-1785. Epub 2023 Apr 20 doi: 10.1016/S0140-6736(23)00725-0. PMID: 37086745
Hurvitz SA, Hegg R, Chung WP, Im SA, Jacot W, Ganju V, Chiu JWY, Xu B, Hamilton E, Madhusudan S, Iwata H, Altintas S, Henning JW, Curigliano G, Perez-Garcia JM, Kim SB, Petry V, Huang CS, Li W, Frenel JS, Antolin S, Yeo W, Bianchini G, Loi S, Tsurutani J, Egorov A, Liu Y, Cathcart J, Ashfaque S, Cortés J
Lancet 2023 Jan 14;401(10371):105-117. Epub 2022 Dec 7 doi: 10.1016/S0140-6736(22)02420-5. PMID: 36495879
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im SA, Shaw Wright G, Henschel V, Molinero L, Chui SY, Funke R, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Trial Investigators
N Engl J Med 2018 Nov 29;379(22):2108-2121. Epub 2018 Oct 20 doi: 10.1056/NEJMoa1809615. PMID: 30345906
Bennouna J, Sastre J, Arnold D, Österlund P, Greil R, Van Cutsem E, von Moos R, Viéitez JM, Bouché O, Borg C, Steffens CC, Alonso-Orduña V, Schlichting C, Reyes-Rivera I, Bendahmane B, André T, Kubicka S; ML18147 Study Investigators
Lancet Oncol 2013 Jan;14(1):29-37. Epub 2012 Nov 16 doi: 10.1016/S1470-2045(12)70477-1. PMID: 23168366

Diagnosis

Pierre ME, Manneh R, Hernández A, Rodríguez J, Fletcher AV, Ramírez HM, Niño OM, Gómez DA, Sanabria D, Contreras F, Pieschacón JR, Calderón PH
Rev Colomb Obstet Ginecol 2024 Jun 14;75(1) doi: 10.18597/rcog.4094. PMID: 39013199Free PMC Article
Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y
JAMA Oncol 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074. PMID: 36301572Free PMC Article
Ohba A, Morizane C, Ueno M, Kobayashi S, Kawamoto Y, Komatsu Y, Ikeda M, Sasaki M, Okano N, Furuse J, Hiraoka N, Yoshida H, Kuchiba A, Sadachi R, Nakamura K, Matsui N, Nakamura Y, Okamoto W, Yoshino T, Okusaka T
Future Oncol 2022 Jun;18(19):2351-2360. Epub 2022 May 5 doi: 10.2217/fon-2022-0214. PMID: 35510484
Dickson MA
Curr Treat Options Oncol 2014 Sep;15(3):476-81. doi: 10.1007/s11864-014-0299-z. PMID: 24968875
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815

Therapy

Dri A, Arpino G, Bianchini G, Curigliano G, Danesi R, De Laurentiis M, Del Mastro L, Fabi A, Generali D, Gennari A, Guarneri V, Santini D, Simoncini E, Zamagni C, Puglisi F
Cancer Treat Rev 2024 Feb;123:102672. Epub 2023 Dec 14 doi: 10.1016/j.ctrv.2023.102672. PMID: 38118302
Hurvitz SA, Hegg R, Chung WP, Im SA, Jacot W, Ganju V, Chiu JWY, Xu B, Hamilton E, Madhusudan S, Iwata H, Altintas S, Henning JW, Curigliano G, Perez-Garcia JM, Kim SB, Petry V, Huang CS, Li W, Frenel JS, Antolin S, Yeo W, Bianchini G, Loi S, Tsurutani J, Egorov A, Liu Y, Cathcart J, Ashfaque S, Cortés J
Lancet 2023 Jan 14;401(10371):105-117. Epub 2022 Dec 7 doi: 10.1016/S0140-6736(22)02420-5. PMID: 36495879
Rugo HS, Bianchini G, Cortes J, Henning JW, Untch M
ESMO Open 2022 Aug;7(4):100553. Epub 2022 Aug 11 doi: 10.1016/j.esmoop.2022.100553. PMID: 35964548Free PMC Article
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im SA, Shaw Wright G, Henschel V, Molinero L, Chui SY, Funke R, Husain A, Winer EP, Loi S, Emens LA; IMpassion130 Trial Investigators
N Engl J Med 2018 Nov 29;379(22):2108-2121. Epub 2018 Oct 20 doi: 10.1056/NEJMoa1809615. PMID: 30345906

Prognosis

Vidal-Jove J, Serres X, Vlaisavljevich E, Cannata J, Duryea A, Miller R, Merino X, Velat M, Kam Y, Bolduan R, Amaral J, Hall T, Xu Z, Lee FT Jr, Ziemlewicz TJ
Int J Hyperthermia 2022;39(1):1115-1123. doi: 10.1080/02656736.2022.2112309. PMID: 36002243
Kwapisz D
Cancer Immunol Immunother 2021 Mar;70(3):607-617. Epub 2020 Oct 5 doi: 10.1007/s00262-020-02736-z. PMID: 33015734Free PMC Article
Diéras V, Miles D, Verma S, Pegram M, Welslau M, Baselga J, Krop IE, Blackwell K, Hoersch S, Xu J, Green M, Gianni L
Lancet Oncol 2017 Jun;18(6):732-742. Epub 2017 May 16 doi: 10.1016/S1470-2045(17)30312-1. PMID: 28526536Free PMC Article
Mavrogenis AF, Mimidis G, Kokkalis ZT, Karampi ES, Karampela I, Papagelopoulos PJ, Armaganidis A
Eur J Orthop Surg Traumatol 2014 Apr;24(3):279-83. Epub 2013 Sep 8 doi: 10.1007/s00590-013-1311-1. PMID: 24013815
Bennouna J, Sastre J, Arnold D, Österlund P, Greil R, Van Cutsem E, von Moos R, Viéitez JM, Bouché O, Borg C, Steffens CC, Alonso-Orduña V, Schlichting C, Reyes-Rivera I, Bendahmane B, André T, Kubicka S; ML18147 Study Investigators
Lancet Oncol 2013 Jan;14(1):29-37. Epub 2012 Nov 16 doi: 10.1016/S1470-2045(12)70477-1. PMID: 23168366

Clinical prediction guides

Hua Y, Sun Z, Xiao Y, Li H, Ma X, Luo X, Tan W, Xie Z, Zhang Z, Tang C, Zhuang H, Xu W, Zhu H, Chen Y, Shang C
J Immunother Cancer 2024 Jul 18;12(7) doi: 10.1136/jitc-2024-008953. PMID: 39029924Free PMC Article
Loap P, Loirat D, Berger F, Rodrigues M, Bazire L, Pierga JY, Vincent-Salomon A, Laki F, Boudali L, Raizonville L, Mosseri V, Jochem A, Eeckhoutte A, Diallo M, Stern MH, Fourquet A, Kirova Y
JAMA Oncol 2022 Dec 1;8(12):1802-1808. doi: 10.1001/jamaoncol.2022.5074. PMID: 36301572Free PMC Article
Vidal-Jove J, Serres X, Vlaisavljevich E, Cannata J, Duryea A, Miller R, Merino X, Velat M, Kam Y, Bolduan R, Amaral J, Hall T, Xu Z, Lee FT Jr, Ziemlewicz TJ
Int J Hyperthermia 2022;39(1):1115-1123. doi: 10.1080/02656736.2022.2112309. PMID: 36002243
Rugo HS, Bianchini G, Cortes J, Henning JW, Untch M
ESMO Open 2022 Aug;7(4):100553. Epub 2022 Aug 11 doi: 10.1016/j.esmoop.2022.100553. PMID: 35964548Free PMC Article
Emens LA, Molinero L, Loi S, Rugo HS, Schneeweiss A, Diéras V, Iwata H, Barrios CH, Nechaeva M, Nguyen-Duc A, Chui SY, Husain A, Winer EP, Adams S, Schmid P
J Natl Cancer Inst 2021 Aug 2;113(8):1005-1016. doi: 10.1093/jnci/djab004. PMID: 33523233Free PMC Article

Recent systematic reviews

Ciapponi A, Bardach A, Colaci C, Rodríguez Cairoli F, Argento F, Korbenfeld E, García Martí S
Rev Peru Med Exp Salud Publica 2024 May 27;41(1):7-18. doi: 10.17843/rpmesp.2024.411.13351. PMID: 38808848Free PMC Article
Haiderali A, Huang M, Pan W, Akers KG, Maciel D, Frederickson AM
Future Oncol 2024;20(22):1587-1600. Epub 2024 Apr 10 doi: 10.2217/fon-2023-0301. PMID: 38597713Free PMC Article
Dai Y, Liang P, Yu J
Curr Oncol Rep 2022 Nov;24(11):1443-1459. Epub 2022 Jun 14 doi: 10.1007/s11912-022-01290-4. PMID: 35699836
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Nishikawa G, Luo J, Prasad V
Eur J Cancer 2018 Sep;101:143-151. Epub 2018 Jul 27 doi: 10.1016/j.ejca.2018.06.010. PMID: 30059818

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