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LOC127889750 H3K4me1 hESC enhancer GRCh37_chr18:77825575-77826076 [ Homo sapiens (human) ]

Gene ID: 127889750, updated on 12-Sep-2024

Summary

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Gene symbol
LOC127889750
Gene description
H3K4me1 hESC enhancer GRCh37_chr18:77825575-77826076
Gene type
biological region
Feature type(s)
regulatory: enhancer
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K4me1 histone modification. [provided by RefSeq, Dec 2022]
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Genomic context

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See LOC127889750 in Genome Data Viewer
Location:
chromosome: 18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (80065575..80066076)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (80342084..80342585)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (77825575..77826076)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene heat shock factor binding protein 1 like 1 Neighboring gene thioredoxin like 4A Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9585 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9586 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:77762974-77763187 Neighboring gene OCT4 hESC enhancer GRCh37_chr18:77766658-77767159 Neighboring gene Sharpr-MPRA regulatory region 15651 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9587 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:77793921-77794077 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9589 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9590 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr18:77808538-77809737 Neighboring gene ribosome binding factor A Neighboring gene RBFA downstream neighbor Neighboring gene solute carrier family 25 member 6 pseudogene 4 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:77861530-77862273 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77865569-77866070 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:77866897-77867398 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9592 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr18:77876558-77877483 Neighboring gene ADNP homeobox 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_139264.1 

    Range
    101..602
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    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    80065575..80066076
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    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    80342084..80342585
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    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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