7K27: Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ATR inhibitor AZ20

PDB ID: 7K27Download
MMDB ID: 206747
PDB Deposition Date: 2020/9/8
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 7K27: monomeric; determined by author and by software (PISA)
Molecular Components in 7K27
Label Count Molecule
Protein (1 molecule)
1
Transcription Initiation Factor Tfiid Subunit 1
(Gene symbol: TAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303