> Census of bacterial signal transduction proteins Signal transduction proteins encoded in genomes of 555 bacterial and archaeal speciesa

This census is a web supplement to the paper "Interplay of heritage and habitat in the distribution of bacterial signal transduction systems"
by Michael Y. Galperin, Roger Higdon, and Eugene Kolker, published in in Mol. BioSyst. 2010, 6: 721-728. Abstract. Article outline.
It was a part of the Sentra database project (see the Abstract of the 2007 NAR database paper), which is no longer maintained
at the Argonne National Lab. You are welcome to cite either of these publications.

For a more recent update on c-di-GMP-related enzymes and receptors, see the c-di-GMP census.

A previous version of this census, covering genomes of 167 species, was created as a web supplement to the paper "A census
of membrane-bound and intracellular signal transduction proteins in bacteria: Bacterial IQ, extroverts and introverts
"
by M.Y. Galperin, published in BMC Microbiology 2005, 5:35. Abstract. Full text (PDF). In 2007, it was expanded to 330 genomes.

An earlier version of this table, prepared for the review "Bacterial signal transduction network in a genomic perspective"
by M.Y. Galperin, published in Environ. Microbiol. 2004, 6, 552-567. Abstract. Full text (PDF) .

The first variant of this table, prepared for the review "Novel domains of the prokaryotic two-component signal transduction system",
by M.Y. Galperin, A.N. Nikolskaya and E.V. Koonin, published in FEMS Microbiol. Lett. 2001, 203, 11-21. Abstract. Full text (PDF).

Please send your corrections, questions and comments to Michael Galperin.

No.
Organism name
GenBank
entry
All
prot.
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
All
total
IQ
1
Candidatus Koribacter versatilis
CP000360
4777
67
3
6
-
2
10
-
4
1
31
15
99
238
126
2
Candidatus Solibacter usitatus
CP000473
7826
110
4
3
-
1
1
-
3
1
84
16
102
325
93
  Actinobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
3
Acidothermus cellulolyticus
CP000481
2157
16
5
6
7
3
1
-
-
-
6
4
23
71
145
4
Arthrobacter aurescens
CP000474
4587
24
-
3
3
2
-
-
1
0*
8
5
20
67
67
5
Arthrobacter sp. FB24
CP000454
4506
29
-
1
4
4
-
-
1
0*
10
3
28
81
78
6
Bifidobacterium adolescentis
AP009256
1631
12
-
-
-
-
-
-
-
-
6
2
14
34
137
7
Bifidobacterium longum
AE014295
1727
9
-
-
-
-
-
-
-
-
7
2
10
28
121
8
Clavibacter michiganensis
AM711867
3079
27
-
-
-
-
-
-
-
0*
8
6
28
70
109
9
Corynebacterium diphtheriae
BX248353
2272
11
-
-
-
-
-
-
1
0*
4
1
11
29
96
10
Corynebacterium efficiens
BA000035
2950
13
-
-
-
-
-
-
1
0*
4
2
13
34
77
11
Corynebacterium glutamicum
BA000036
2993
13
-
-
1
-
-
-
1
0*
4
1
14
36
79
12
Corynebacterium jeikeium
CR931997
2137
9
-
-
-
-
-
-
1
-
5
1
9
25
94
13
Corynebacterium urealyticum
AM942444
2024
8
-
-
-
-
-
-
1
-
4
1
9
24
98
14
Frankia alni
CT573213
6711
45
-
9
7
6
1
-
2
1*
59
21
47
200
84
15
Frankia sp. CcI3
CP000249
4499
32
-
6
6
4
-
-
3
0*
35
16
31
134
104
16
Frankia sp. EAN1pec
CP000820
7191
64
-
26
10
9
-
-
5
0*
69
20
66
279
94
17
Kineococcus radiotolerans
CP000750
4681
38
22
39
34
10
1
-
-
0*
8
31
41
227
126
18
Kocuria rhizophila
AP009152
2357
13
-
-
-
-
-
-
1
0*
7
2
14
39
107
19
Leifsonia xyli
AE016822
2030
16
-
-
-
-
-
-
-
-
6
2
21
45
129
20
Mycobacterium abscessus
CU458896
4920
17
-
4
-
-
-
-
5
0*
17
1
19
64
58
21
Mycobacterium avium
AE016958
4350
19
-
2
2
1
1
-
12
0*
12
5
18
74
77
22
Mycobacterium bovis
BX248333
3920
13
-
-
1
1
-
-
16
0*
13
2
12
59
76
23
Mycobacterium gilvum
CP000656
5579
27
-
14
8
2
1
-
10
0*
15
8
28
119
76
24
Mycobacterium leprae
AL450380
1605
5
-
2
1
1
-
-
4
-
6
1
5
25
123
25
Mycobacterium marinum
CP000854
5452
19
-
-
-
-
-
-
31
0*
27
6
18
104
72
26
Mycobacterium smegmatis
CP000480
6716
34
-
1
1
-
-
-
8
0*
15
3
34
97
48
27
Mycobacterium sp. JLS
CP000580
5739
30
-
6
4
-
1
-
16
0*
16
8
31
115
72
28
Mycobacterium sp. KMS
CP000518
5975
29
-
5
4
-
1
-
15
0*
19
8
31
113
67
29
Mycobacterium sp. MCS
CP000384
5615
26
-
6
4
-
1
-
13
0*
16
8
28
103
68
30
Mycobacterium tuberculosis H37Rv
AL123456
3989
13
-
-
1
1
-
-
16
0*
13
2
13
60
76
31
Mycobacterium ulcerans
CP000325
4160
12
-
-
-
-
-
-
15
0*
14
3
15
60
71
32
Mycobacterium vanbaalenii
CP000511
5979
37
-
10
4
1
1
-
10
0*
13
6
36
119
69
33
Nocardia farcinica
AP006618
5936
37
-
6
2
-
-
-
4
-
25
7
32
113
67
34
Nocardioides sp. JS614
CP000509
4909
53
5
1
2
-
2
-
2
0*
13
7
46
132
94
35
Propionibacterium acnes
AE017283
2297
12
-
-
-
-
-
-
-
0*
4
2
13
32
99
36
Renibacterium salmoninarum
CP000910
3507
17
-
-
-
-
-
-
1
-
7
1
17
44
73
37
Rhodococcus jostii
CP000431
9145
46
-
4
3
-
1
-
7
0*
43
2
41
150
38
38
Rubrobacter xylanophilus
CP000386
3140
20
-
1
5
1
3
-
-
0*
9
4
19
63
102
39
Saccharopolyspora erythraea
AM420293
7197
49
-
14
11
1
1
-
2
-
25
4
49
157
65
40
Salinispora arenicola
CP000850
4917
33
-
8
6
2
-
-
3
-
11
8
32
103
82
41
Salinispora tropica
CP000667
4536
33
-
6
6
-
-
-
3
-
10
7
31
95
86
42
Streptomyces avermitilis
BA000030
7671
78
-
3
4
1
1
-
1
0*
35
50
67
241
80
43
Streptomyces coelicolor
AL645882
8154
95
-
3
4
-
1
-
1
0*
37
51
82
279
81
44
Streptomyces griseus
AP009493
7136
79
-
2
4
-
-
-
1
0*
38
41
75
240
87
45
Thermobifida fusca
CP000088
3110
28
-
1
2
1
2
-
1
-
25
15
27
102
127
46
Tropheryma whipplei
BX072543
783
2
-
-
-
-
-
-
-
-
4
1
2
9
144
  Aquificae
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
47
Aquifex aeolicus
AE000657
1560
4
-
7
4
3
1
-
-
-
2
2
5
28
131
48
Hydrogenobaculum sp. Y04AAS1
CP001130
1629
6
9
10
6
2
-
-
-
-
1
1
8
43
148
49
Sulfurihydrogenibium sp. YO3AOP1
CP001080
1721
11
4
5
5
2
-
-
-
-
2
-
13
41
141
  Bacteroidetes
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
50
Bacteroides fragilis
AP006841
4625
60
-
-
-
-
-
-
-
-
-
1
27
88
80
51
Bacteroides thetaiotaomicron
AE015928
4816
85
-
-
-
-
-
-
-
-
2
1
26
114
89
52
Bacteroides vulgatus
CP000139
4065
48
-
-
-
-
-
-
-
-
1
-
21
68
80
53
Candidatus Amoebophilus asiaticus
CP001102
1283
3
-
-
-
-
-
-
-
-
6
-
-
6
74
54
Candidatus Azobacteroides pseudotrichonymphae
AP010656
852
-
-
-
-
-
-
-
-
-
-
-
-
0
0
55
Candidatus Sulcia muelleri
CP000770
227
-
-
-
-
-
-
-
-
-
-
-
-
0
0
56
Cytophaga hutchinsonii
CP000383
3785
57
-
-
-
-
-
-
-
-
2
3
34
96
104
57
Flavobacterium johnsoniae
CP000685
5017
69
-
-
-
-
-
-
-
-
-
1
69
133
92
58
Flavobacterium psychrophilum
AM398681
2412
12
-
-
-
-
-
-
-
-
-
-
17
29
90
59
Gramella forsetii
CU207366
3584
31
-
-
-
-
-
-
2
-
2
-
34
71
95
60
Parabacteroides distasonis
CP000140
3850
63
-
-
-
-
-
-
-
-
-
2
28
89
99
61
Porphyromonas gingivalis
AE015924
1909
6
-
-
-
-
-
-
-
-
-
-
6
12
69
62
Salinibacter ruber
CP000159
2833
51
13
-
1
-
-
-
-
-
4
1
26
96
133
  Chlamydiae
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
63
Candidatus Protochlamydia amoebophila
BX908798
2031
2
-
-
-
-
-
-
-
-
4
3
2
11
58
64
Chlamydia muridarum
AE002160
904
1
-
-
-
-
-
-
-
-
3
3
2
9
129
65
Chlamydia trachomatis
AE001273
895
1
-
-
-
-
-
-
-
-
3
3
2
9
130
66
Chlamydophila abortus
CR848038
932
1
-
-
-
-
-
-
-
-
3
3
2
9
126
67
Chlamydophila caviae
AE015925
1005
1
-
-
-
-
-
-
-
-
3
3
2
9
119
68
Chlamydophila felis
AP006861
1013
1
-
-
-
-
-
-
-
-
3
3
2
9
118
69
Chlamydophila pneumoniae
AE001363
1054
1
-
-
-
-
-
-
-
-
3
3
2
9
114
  Chlorobi
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
70
Chlorobaculum parvum
CP001099
2043
10
-
1
-
-
-
-
1
-
-
-
7
30
108
71
Chlorobium chlorochromatii
CP000108
2002
4
-
1
-
-
-
-
-
-
1
-
3
9
50
72
Chlorobium limicola
CP001097
2434
13
-
1
-
-
-
-
1
-
-
1
7
37
101
73
Chlorobium phaeobacteroides
CP000492
2650
13
-
1
-
-
-
-
1
-
-
1
4
20
62
74
Chlorobium phaeovibrioides
CP000607
1753
9
-
1
-
-
1
-
-
-
-
-
6
18
98
75
Chlorobium tepidum
AE006470
2252
8
-
1
-
-
-
-
1
-
-
-
4
14
60
76
Chloroherpeton thalassium
CP001100
2710
35
2
8
-
-
6
-
4
1
-
2
25
108
144
77
Chlorobium luteolum
CP000096
2083
19
-
1
-
-
1
-
-
-
-
3
14
38
118
78
Pelodictyon phaeoclathratiforme
CP001110
2707
20
-
1
-
-
-
-
-
-
2
2
6
51
106
79
Prosthecochloris aestuarii
CP001108
2327
8
-
1
-
-
-
-
1
-
-
-
6
24
84
  Chloroflexi
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
80
Chloroflexus aurantiacus
CP000909
3853
67
2
14
3
-
4
-
-
-
16
15
56
181
134
81
Dehalococcoides ethenogenes
CP000027
1580
19
-
1
-
-
3
-
-
-
-
-
25
48
157
82
Dehalococcoides sp. BAV1
CP000688
1371
15
-
1
-
-
-
-
-
-
-
-
18
33
152
83
Dehalococcoides sp. CBDB1
AJ965256
1458
26
-
1
-
-
3
-
-
-
-
-
28
58
175
84
Herpetosiphon aurantiacus
CP000875
5278
90
1
11
3
-
4
-
-
-
39
22
86
260
121
85
Roseiflexus castenholzii
CP000804
4330
60
3
8
3
-
5
-
-
-
27
12
61
180
122
86
Roseiflexus sp. RS-1
CP000686
4517
62
3
8
3
-
5
-
-
-
29
13
62
184
119
  Cyanobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
87
Acaryochloris marina
CP000828
8383
91
7
26
27
5
-
-
8
-
64
7
81
304
82
88
Anabaena variabilis
CP000117
5657
129
3
8
6
1
2
-
5
-
59
9
65
287
119
89
Cyanothece sp. ATCC 51142
CP000806
5304
50
5
12
18
2
2
-
3
-
26
5
45
165
98
90
Cyanothece sp. PCC 7424
CP001291
5710
72
9
18
14
-
2
-
3
-
35
6
64
217
104
91
Cyanothece sp. PCC 8801
CP001287
4367
43
8
13
10
2
2
-
3
-
22
10
42
155
114
92
Gloeobacter violaceus
BA000045
4430
46
-
1
-
-
1
-
1
1
19
4
38
111
96
93
Microcystis aeruginosa
AP009552
6312
21
1
1
1
-
1
-
1
-
25
6
20
76
42
94
Nostoc punctiforme
CP001037
6690
158
7
11
10
1
2
-
8
-
60
9
84
331
109
95
Nostoc sp. PCC 7120
BA000019
6055
134
3
8
6
1
2
-
6
-
52
9
70
291
113
96
Prochlorococcus marinus
AE017126
1882
5
-
-
-
-
-
-
-
-
3
1
6
15
81
97
Synechococcus elongatus
AP008231
2525
15
2
9
8
1
2
-
2
-
8
3
17
67
127
98
Synechococcus sp. CC9311
CP000435
2892
11
-
1
3
-
-
-
1
-
5
1
16
38
85
99
Synechococcus sp. CC9605
CP000110
2645
6
-
-
-
-
-
-
1
-
4
1
9
21
64
100
Synechococcus sp. CC9902
CP000097
2307
7
-
-
-
-
-
-
-
-
4
1
7
19
73
101
Synechococcus sp. JA-3-3Ab
CP000239
2760
22
3
3
-
1
2
-
1
-
13
3
26
74
123
102
Synechococcus sp. PCC 7002
CP000951
3186
34
3
7
6
2
-
-
1
-
14
7
29
104
126
103
Synechococcus sp. RCC307
CT978603
2525
9
-
-
-
-
-
-
-
-
5
1
10
24
76
104
Synechococcus sp. WH 7803
CT971583
2533
10
-
-
-
-
-
-
-
-
5
1
13
28
83
105
Synechococcus sp. WH 8102
BX548020
2517
6
-
-
-
-
-
-
-
-
3
1
9
19
64
106
Synechocystis sp. PCC 6803
BA000022
3567
46
4
13
9
5
2
-
3
-
12
8
34
136
128
107
Thermosynechococcus elongatus
BA000039
2475
19
4
4
5
-
1
-
2
-
17
5
21
77
136
108
Trichodesmium erythraeum
CP000393
5124
35
3
1
3
-
2
-
13
-
48
10
24
139
93
  Deinococcus/ Thermus
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
109
Deinococcus geothermalis
CP000359
2857
28
-
9
-
-
5
-
1
-
5
1
30
79
123
110
Deinococcus radiodurans
AE000513
3184
21
3
12
4
1
4
-
-
-
9
3
24
81
113
111
Thermus thermophilus
AE017221
2210
11
-
5
1
-
5
-
1
-
4
2
13
42
117
  Dictyoglomi
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
112
Dictyoglomus thermophilum
CP001146
1912
4
-
9
-
-
8
-
1
-
2
1
6
31
116
113
Dictyoglomus turgidum
CP001251
1744
6
-
8
-
-
9
-
1
-
1
1
8
34
130
  Elusimicrobia
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
114
Elusimicrobium minutum
CP001055
1529
6
-
2
-
-
1
-
-
-
3
2
5
19
114
115
Uncultured Termite group 1 bacterium phylotype Rs-D17
AP009510
776
-
-
-
-
-
-
-
-
-
-
-
-
0
0
  Firmicutes
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
116
Alkaliphilus metalliredigens
CP000724
4625
62
25
10
4
1
16
-
-
-
4
6
61
189
118
117
Alkaliphilus oremlandii
CP000853
2836
34
20
9
4
1
3
-
-
-
3
3
36
114
142
118
Anoxybacillus flavithermus
CP000922
2832
23
17
12
6
2
8
-
-
-
3
3
20
97
134
119
Bacillus amyloliquefaciens
CP000560
3693
37
8
4
-
2
-
-
-
-
4
4
36
93
105
120
Bacillus anthracis str. Ames
AE016879
5311
47
13
3
6
1
1
-
-
-
5
4
46
128
85
121
Bacillus cereus
AE016877
5255
53
13
3
4
1
-
-
-
-
5
5
45
129
86
122
Bacillus clausii
AP006627
4096
43
7
1
-
1
1
-
-
-
6
4
41
104
100
123
Bacillus halodurans
BA000004
4066
44
12
3
1
1
2
-
-
-
4
4
46
117
107
124
Bacillus licheniformis
AE017333
4196
36
11
4
-
2
-
-
-
-
3
4
37
97
95
125
Bacillus pumilus
CP000813
3681
31
16
4
1
2
-
-
-
-
3
4
29
95
107
126
Bacillus subtilis
AL009126
4105
36
10
3
1
2
-
-
-
-
4
5
35
97
97
127
Bacillus thuringiensis
AE017355
5117
58
12
3
6
1
1
-
-
-
4
5
50
140
93
128
Bacillus weihenstephanensis
CP000903
5653
65
12
3
6
1
-
-
-
-
5
7
54
152
87
129
Caldicellulosiruptor saccharolyticus
CP000679
2679
23
10
4
3
-
10
-
1
-
2
3
29
84
132
130
Candidatus Desulforudis audaxviator
CP000860
2157
10
4
11
1
-
16
-
-
-
3
3
11
59
136
131
Carboxydothermus hydrogenoformans
CP000141
2620
14
11
10
1
1
13
-
-
-
4
2
19
75
129
132
Clostridium acetobutylicum
AE001437
3848
37
38
7
3
1
9
-
-
1
5
4
43
148
124
133
Clostridium beijerinckii
CP000721
5020
93
61
15
9
1
15
-
-
-
5
5
75
276
129
134
Clostridium botulinum
AM412317
3590
37
24
8
1
1
6
-
-
-
4
3
42
126
123
135
Clostridium difficile
AM180355
3753
50
1
18
18
1
-
-
-
-
3
3
52
146
126
136
Clostridium kluyveri
CP000673
3913
44
37
8
3
4
7
-
-
-
6
2
40
151
124
137
Clostridium novyi
CP000382
2325
22
17
4
3
1
4
-
-
1
5
2
19
78
143
138
Clostridium perfringens
BA000016
2723
27
-
5
1
2
1
-
-
1
3
2
21
63
116
139
Clostridium phytofermentans
CP000885
3902
59
28
9
5
-
7
-
-
-
3
3
62
174
131
140
Clostridium tetani
AE015927
2432
31
20
6
-
1
1
-
-
1
1
2
30
93
147
141
Clostridium thermocellum
CP000568
3189
33
15
9
1
-
8
-
-
-
6
8
30
110
128
142
Coprothermobacter proteolyticus
CP001145
1482
5
3
2
-
-
4
-
-
-
-
1
6
22
124
143
Desulfitobacterium hafniense
AP008230
5060
66
39
16
4
3
15
-
-
-
3
4
71
221
117
144
Desulfotomaculum reducens
CP000612
3276
30
23
13
1
1
15
-
1
-
2
4
30
120
130
145
Enterococcus faecalis
AE016830
3265
16
-
1
-
-
-
-
-
-
1
1
18
37
71
146
Exiguobacterium sibiricum
CP001022
3015
31
12
14
11
3
2
-
-
-
3
2
24
102
130
147
Finegoldia magna
AP008971
1813
12
-
-
-
-
-
-
-
-
2
3
13
31
121
148
Geobacillus kaustophilus
BA000043
3540
26
6
5
3
2
3
-
-
-
5
6
28
84
104
149
Geobacillus thermodenitrificans
CP000557
3445
27
5
5
2
2
2
-
-
-
5
5
28
81
105
150
Heliobacterium modesticaldum
CP000930
3000
28
22
4
3
2
11
-
-
-
3
4
25
103
131
151
Lactobacillus acidophilus
CP000033
1864
8
-
1
-
1
-
-
-
-
1
1
8
20
97
152
Lactobacillus brevis
CP000416
2218
10
-
2
-
3
-
-
-
-
2
1
10
28
96
153
Lactobacillus casei
CP000423
2771
15
-
-
-
-
-
-
-
-
1
1
17
34
84
154
Lactobacillus delbrueckii
CR954253
1562
6
-
3
-
-
-
-
-
-
2
1
6
18
109
155
Lactobacillus fermentum
AP008937
1843
5
-
-
-
-
-
-
-
-
1
1
6
13
76
156
Lactobacillus gasseri
CP000413
1755
5
-
-
-
-
-
-
-
-
1
1
5
12
77
157
Lactobacillus helveticus
CP000517
1610
4
-
-
-
-
-
-
-
-
1
1
4
10
77
158
Lactobacillus johnsonii
AE017198
1821
9
-
-
-
-
-
-
-
-
1
1
9
20
99
159
Lactobacillus plantarum
AL935263
3059
14
-
3
-
5
-
-
-
-
3
1
15
41
83
160
Lactobacillus reuteri
CP000705
1900
7
-
1
-
2
-
-
-
-
1
1
9
21
97
161
Lactobacillus sakei
CR936503
1879
9
-
-
-
-
-
-
-
-
1
1
10
21
98
162
Lactobacillus salivarius
CP000233
2017
8
-
1
-
1
-
-
-
-
-
1
9
20
89
163
Lactococcus lactis
AE005176
2321
7
-
-
-
-
-
-
-
-
1
1
7
16
64
164
Leuconostoc citreum
DQ489736
1820
7
-
1
-
1
-
-
-
-
1
1
7
23
106
165
Leuconostoc mesenteroides
CP000414
2005
10
-
1
-
1
-
-
-
-
1
1
10
24
99
166
Listeria innocua
AL592022
2968
15
2
3
-
3
-
-
-
-
2
3
18
46
92
167
Listeria monocytogenes
AL591824
2846
15
2
3
-
3
-
-
-
-
2
3
15
43
93
168
Listeria welshimeri
AM263198
2774
16
2
4
-
3
-
-
-
-
2
3
19
49
102
169
Lysinibacillus sphaericus
CP000817
4771
47
41
10
8
3
3
-
-
-
5
6
53
180
113
170
Moorella thermoacetica
CP000232
2465
14
6
8
-
1
10
-
-
-
3
4
15
61
125
171
Natranaerobius thermophilus
CP001034
2906
15
13
11
-
-
15
-
2
-
6
4
23
90
128
172
Oceanobacillus iheyensis
BA000028
3500
19
8
2
1
1
2
-
-
-
4
4
21
62
90
173
Oenococcus oeni
CP000411
1691
6
-
1
-
1
-
-
-
-
1
1
6
16
95
174
Pediococcus pentosaceus
CP000422
1755
8
-
1
-
4
-
-
-
-
1
1
9
24
112
175
Pelotomaculum thermopropionicum
AP009389
2920
20
13
8
-
1
14
-
2
-
2
4
25
87
125
176
Staphylococcus aureus
BA000018
2624
17
-
1
-
-
-
-
-
-
2
2
17
39
96
177
Staphylococcus epidermidis
AE015929
2419
15
-
1
-
-
-
-
-
-
2
2
16
36
100
178
Staphylococcus haemolyticus
AP006716
2676
16
-
1
-
-
-
-
-
-
1
2
15
35
89
179
Staphylococcus saprophyticus
AP008934
2514
11
-
1
-
-
-
-
-
-
1
2
11
26
80
180
Streptococcus agalactiae
AE009948
2124
18
-
-
-
-
-
-
-
-
1
1
20
40
118
181
Streptococcus equi
CP001129
1893
13
-
-
-
-
-
-
-
-
1
1
15
30
115
182
Streptococcus gordonii
CP000725
2051
15
-
-
-
-
-
-
-
-
1
1
16
33
112
183
Streptococcus mutans
AE014133
1960
14
-
-
-
-
-
-
-
-
1
1
14
30
112
184
Streptococcus pneumoniae
AE005672
2094
13
-
-
-
-
-
-
-
-
4
1
14
32
109
185
Streptococcus pyogenes
AE004092
1697
12
-
-
-
-
-
-
-
-
1
1
12
26
119
186
Streptococcus sanguinis
CP000387
2270
14
-
-
-
-
-
-
-
-
1
1
15
31
99
187
Streptococcus suis
CP000407
2186
10
-
-
-
-
-
-
-
-
1
1
12
23
88
188
Streptococcus thermophilus
CP000024
1915
9
-
-
-
-
-
-
-
-
4
1
10
24
103
189
Symbiobacterium thermophilum
AP006840
3337
27
13
6
3
-
4
-
-
-
1
3
33
90
114
190
Syntrophomonas wolfei
CP000448
2504
19
9
8
-
-
18
-
1
-
4
4
20
83
138
191
Thermoanaerobacter pseudethanolicus
CP000924
2243
8
5
3
-
1
7
-
-
-
2
3
11
41
114
192
Thermoanaerobacter sp. X514
CP000923
2349
12
3
3
-
1
9
-
-
-
3
3
15
51
120
193
Thermoanaerobacter tengcongensis
AE008691
2588
17
9
5
1
-
6
-
-
-
3
4
18
63
121
  Proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
  Alpha-proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
194
Acidiphilium cryptum
CP000697
3559
17
11
5
4
-
-
-
1
-
2
1
21
71
95
195
Agrobacterium tumefaciens
AE008688
5402
53
20
14
13
1
1
-
3
-
2
1
55
163
95
196
Anaplasma marginale
CP000030
949
3
-
1
-
-
-
-
-
-
1
-
2
7
112
197
Anaplasma phagocytophilum
CP000235
1264
3
-
1
-
-
-
-
-
-
1
-
2
7
83
198
Azorhizobium caulinodans
AP009384
4717
46
42
24
10
4
1
-
1
-
6
3
55
189
116
199
Bartonella bacilliformis
CP000524
1283
10
-
-
1
-
-
-
-
-
1
-
12
23
141
200
Bartonella henselae
BX897699
1488
11
-
-
1
-
-
-
-
-
1
-
11
24
128
201
Bartonella quintana
BX897700
1142
11
-
-
1
-
-
-
-
-
1
-
11
24
155
202
Bartonella tribocorum
AM260525
2092
11
-
-
1
-
-
-
-
-
1
-
11
24
94
203
Beijerinckia indica
CP001016
3784
37
4
1
1
1
-
-
1
-
2
-
37
80
95
204
Bradyrhizobium japonicum
BA000040
8317
92
35
12
23
4
3
-
37
-
4
2
90
302
83
205
Bradyrhizobium sp. BTAi1
CP000494
7622
91
60
15
15
3
4
-
12
-
3
1
75
266
85
206
Bradyrhizobium sp. ORS278
CU234118
6717
80
48
15
15
3
2
-
15
-
4
1
67
239
93
207
Brucella abortus
AE017223
3085
20
-
2
2
2
-
-
-
-
1
-
21
49
91
208
Brucella canis
CP000872
3251
21
-
6
3
2
-
-
-
-
1
-
19
51
88
209
Brucella melitensis
AE008917
3198
22
-
6
3
2
-
-
-
-
1
-
21
56
94
210
Brucella ovis
CP000709
2890
20
-
3
3
-
-
-
-
-
1
-
20
46
95
211
Brucella suis
AE014291
3271
21
-
5
3
2
-
-
-
-
2
-
21
54
90
212
Candidatus Pelagibacter ubique
CP000084
1354
5
-
-
-
-
-
-
-
-
1
4
5
15
114
213
Caulobacter crescentus
AE005673
3737
62
18
4
7
3
-
-
3
-
2
-
43
142
125
214
Caulobacter sp. K31
CP000927
5438
79
16
3
4
3
-
-
-
-
6
-
58
156
92
215
Dinoroseobacter shibae
CP000830
4187
29
-
2
1
1
-
-
-
-
2
1
28
64
74
216
Ehrlichia canis
CP000107
925
3
-
1
-
-
-
-
-
-
1
-
2
7
114
217
Ehrlichia chaffeensis
CP000236
1105
3
-
1
-
-
-
-
-
-
1
-
2
7
97
218
Ehrlichia ruminantium
CR767821
888
3
-
2
-
-
-
-
-
-
1
-
2
8
125
219
Erythrobacter litoralis
CP000157
3011
23
2
3
7
1
-
-
-
-
5
-
23
64
107
220
Gluconacetobacter diazotrophicus
AM889285
3852
21
9
-
-
-
-
-
2
-
2
-
28
85
96
221
Gluconobacter oxydans
CP000009
2664
16
3
2
4
1
-
-
1
-
2
-
19
48
105
222
Granulibacter bethesdensis
CP000394
2437
19
-
-
-
-
-
-
1
-
1
-
20
41
106
223
Hyphomonas neptunium
CP000158
3505
28
-
10
9
2
-
-
-
-
8
1
25
83
105
224
Jannaschia sp. CCS1
CP000264
4283
22
4
2
8
2
-
-
2
-
5
4
24
73
78
225
Magnetospirillum magneticum
AP007255
4559
104
65
29
17
10
16
-
7
-
10
9
77
344
150
226
Maricaulis maris
CP000449
3063
36
8
7
5
3
-
-
1
-
1
1
36
98
127
227
Mesorhizobium loti
BA000012
7275
62
1
16
16
2
1
-
12
-
3
2
55
170
68
228
Mesorhizobium sp. BNC1
CP000390
4543
32
1
4
7
1
-
-
-
-
2
-
34
81
78
229
Methylobacterium chloromethanicum
CP001298
5516
95
32
16
18
5
7
-
6
-
5
3
71
240
112
230
Methylobacterium extorquens
CP000908
4829
82
27
17
14
4
6
-
5
-
4
1
71
213
120
231
Methylobacterium populi
CP001029
5365
104
28
18
11
3
4
-
8
-
4
1
74
237
115
232
Methylobacterium radiotolerans
CP001001
6431
112
48
10
20
4
6
-
15
-
5
3
88
287
106
233
Methylobacterium sp. 4-46
CP000943
6692
101
40
12
17
1
5
-
21
-
5
3
82
268
99
234
Methylocella silvestris
CP001280
3818
40
1
5
4
-
-
-
3
-
6
2
44
101
106
235
Neorickettsia sennetsu
CP000237
932
3
-
1
-
1
-
-
-
-
1
-
1
7
114
236
Nitrobacter hamburgensis
CP000319
4326
41
4
6
5
3
1
-
1
-
2
-
36
99
93
237
Nitrobacter winogradskyi
CP000115
3122
26
2
4
4
2
1
-
2
-
2
-
26
69
107
238
Novosphingobium aromaticivorans
CP000248
3324
33
5
1
7
1
1
-
1
-
2
1
33
85
111
239
Ochrobactrum anthropi
CP000758
4799
32
-
13
6
-
-
-
-
-
1
-
30
78
70
240
Oligotropha carboxidovorans
CP001196
3722
31
10
13
7
1
1
-
1
-
1
-
32
97
107
241
Orientia tsutsugamushi Boryong
AM494475
1182
38
-
1
-
1
-
-
-
-
1
-
2
31
164
242
Orientia tsutsugamushi str. Ikeda
AP008981
1967
29
-
1
-
1
-
-
-
-
1
-
2
34
118
243
Paracoccus denitrificans
CP000489
5077
34
-
2
-
2
-
-
1
-
2
2
37
80
66
244
Parvibaculum lavamentivorans
CP000774
3636
42
-
4
3
2
-
-
-
-
2
1
38
93
107
245
Phenylobacterium zucineum
CP000747
3854
56
8
4
3
2
-
-
1
-
2
-
47
117
112
246
Rhizobium etli
CP000133
5963
55
27
14
21
-
1
-
22
-
3
1
64
209
98
247
Rhizobium leguminosarum
AM236086
7150
61
28
16
22
-
3
-
29
-
3
2
65
229
84
248
Rhodobacter sphaeroides
CP000143
4126
45
11
9
7
-
-
-
-
-
6
2
49
129
110
249
Rhodopseudomonas palustris
BX571963
4813
66
29
22
14
4
2
-
7
-
5
1
48
198
117
250
Rhodospirillum centenum
CP000613
4002
55
33
8
6
2
2
-
5
-
3
-
51
161
125
251
Rhodospirillum rubrum
CP000230
3841
55
50
21
15
4
2
-
1
-
4
1
48
201
140
252
Rickettsia akari
CP000847
1259
3
-
1
-
1
-
-
-
-
1
-
3
10
101
253
Rickettsia bellii
CP000087
1429
5
-
1
-
1
-
-
-
-
1
-
3
11
93
254
Rickettsia canadensis
CP000409
1093
3
-
1
-
1
-
-
-
-
1
-
3
9
110
255
Rickettsia conorii
AE006914
1374
5
-
1
-
1
-
-
-
-
1
-
3
11
97
256
Rickettsia felis
CP000053
1532
5
-
1
-
1
-
-
-
-
1
-
3
11
86
257
Rickettsia massiliae
CP000683
980
4
-
1
-
1
-
-
-
-
1
-
3
6
101
258
Rickettsia prowazekii
AJ235269
835
4
-
1
-
1
-
-
-
-
1
-
3
10
142
259
Rickettsia rickettsii
CP000766
1384
4
-
1
-
1
-
-
-
-
1
-
3
9
87
260
Rickettsia typhi
AE017197
838
4
-
1
-
1
-
-
-
-
1
-
3
10
142
261
Roseobacter denitrificans
CP000362
4129
25
6
2
6
1
-
-
3
-
2
1
29
75
83
262
Silicibacter pomeroyi
CP000031
4252
23
-
4
1
1
-
-
11
-
2
2
24
68
75
263
Silicibacter sp. TM1040
CP000377
3864
40
19
5
6
2
-
-
7
-
2
2
32
115
111
264
Sinorhizobium medicae
CP000738
6213
51
9
5
13
1
-
-
25
-
1
1
62
162
81
265
Sinorhizobium meliloti
AL591688
6205
48
9
6
11
2
-
-
28
-
2
1
56
163
81
266
Sphingomonas wittichii
CP000699
5345
45
5
12
7
1
1
-
2
-
3
2
50
126
83
267
Sphingopyxis alaskensis
CP000356
3195
19
3
6
6
1
-
-
1
-
1
-
25
62
99
268
Wolbachia endosymbiont of Culex quinquefasciatus Pel
AM999887
1275
2
-
1
-
-
-
-
-
-
1
-
1
5
65
269
Wolbachia endosymbiont of Drosophila melanogaster
AE017196
1195
2
-
1
-
-
-
-
-
-
1
-
1
5
72
270
Wolbachia endosymbiont strain TRS of Brugia malayi
AE017321
805
2
-
1
-
-
-
-
-
-
1
-
1
5
111
271
Xanthobacter autotrophicus
CP000781
5035
49
-
11
7
-
-
-
1
-
5
3
51
124
89
272
Zymomonas mobilis
AE008692
1998
15
3
2
2
1
-
-
-
-
1
-
13
37
121
  Beta-proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
273
Acidovorax citrulli
CP000512
4709
58
40
23
17
4
2
-
3
-
6
6
53
210
122
274
Acidovorax sp. JS42
CP000539
4155
32
19
13
9
3
3
-
-
-
5
3
35
120
106
275
Aromatoleum aromaticum
CR555306
4590
41
2
7
19
4
5
-
1
-
7
4
42
132
101
276
Azoarcus sp. BH72
AM406670
3989
63
24
23
24
4
8
-
3
-
13
7
57
226
142
277
Bordetella avium
AM167904
3381
22
10
8
6
4
1
-
-
-
2
1
27
83
108
278
Bordetella bronchiseptica
BX470250
4994
25
8
10
5
4
2
-
-
-
4
1
32
91
74
279
Bordetella parapertussis
BX470249
4185
22
6
8
5
4
2
-
-
-
4
1
28
80
85
280
Bordetella pertussis
BX470248
3436
18
5
5
2
1
1
-
-
-
3
1
22
58
89
281
Bordetella petrii
AM902716
5027
29
7
-
2
-
-
-
-
-
5
1
34
77
65
282
Burkholderia ambifaria
CP000440
6617
50
18
13
7
7
1
-
1
1
5
-
58
161
74
283
Burkholderia cenocepacia
CP000458
6477
50
21
13
5
6
2
-
-
1
4
-
64
166
78
284
Burkholderia mallei
CP000011
4764
36
17
4
4
4
2
-
-
-
3
-
35
105
86
285
Burkholderia multivorans
CP000869
6259
55
16
9
7
6
-
-
-
2
2
-
61
211
93
286
Burkholderia phymatum
CP001043
7496
87
28
19
18
10
1
-
3
1
5
3
88
257
85
287
Burkholderia phytofirmans
CP001052
7241
76
27
18
16
8
3
-
-
1
6
2
87
241
85
288
Burkholderia pseudomallei
BX571965
5728
45
21
5
5
6
2
-
-
1
4
-
36
125
76
289
Burkholderia sp. 383
CP000150
7717
62
18
14
7
7
1
-
3
1
4
-
73
190
67
290
Burkholderia thailandensis
CP000086
5634
46
20
6
4
4
2
-
1
1
4
-
56
144
85
291
Burkholderia vietnamiensis
CP000616
7617
63
26
21
10
8
1
-
-
1
3
-
68
199
71
292
Burkholderia xenovorans
CP000271
8702
46
33
15
17
12
-
-
1
1
6
2
65
198
57
293
Chromobacterium violaceum
AE016825
4407
50
42
27
16
10
11
-
-
-
4
4
49
213
129
294
Cupriavidus taiwanensis
CU633749
5897
55
13
11
6
2
1
-
3
1
6
2
62
158
85
295
Dechloromonas aromatica
CP000089
4171
103
25
29
28
3
15
-
3
-
9
7
76
298
151
296
Delftia acidovorans
CP000884
6040
75
31
24
17
6
6
-
2
-
6
6
69
242
104
297
Herminiimonas arsenicoxydans
CU207211
3325
36
13
20
14
2
3
-
-
-
3
3
41
134
134
298
Janthinobacterium sp. Marseille
CP000269
3697
45
21
20
13
4
2
-
2
-
4
4
54
166
134
299
Leptothrix cholodnii
CP001013
4363
74
25
20
24
-
8
-
3
-
11
5
66
233
134
300
Methylibium petroleiphilum
CP000555
4449
53
13
11
11
1
3
-
1
-
10
4
47
150
110
301
Methylobacillus flagellatus
CP000284
2753
27
7
9
13
5
2
-
2
-
5
3
37
110
143
302
Neisseria gonorrhoeae
AE004969
2002
4
-
-
-
-
-
-
-
-
1
-
2
7
37
303
Neisseria meningitidis
AE002098
2079
5
-
-
-
-
-
-
-
-
1
-
5
11
56
304
Nitrosomonas europaea
AL954747
2461
15
3
2
4
5
-
-
3
-
2
-
16
50
115
305
Nitrosomonas eutropha
CP000450
2550
15
3
3
4
3
1
-
2
-
2
-
16
49
110
306
Nitrosospira multiformis
CP000103
2805
24
1
6
11
3
1
-
-
-
2
1
22
71
119
307
Polaromonas naphthalenivorans
CP000529
4929
66
1
-
1
-
-
-
2
-
10
4
50
130
93
308
Polaromonas sp. JS666
CP000316
5453
49
4
3
3
1
-
-
4
-
7
5
58
134
84
309
Polynucleobacter necessarius
CP000655
2077
8
-
3
-
-
2
-
-
-
2
-
8
23
93
310
Ralstonia eutropha
CP000090
6446
59
23
17
11
2
3
-
7
1
3
3
65
194
86
311
Ralstonia metallidurans
CP000352
6319
53
16
18
13
10
2
-
-
1
3
2
84
202
90
312
Ralstonia pickettii
CP001068
4952
54
15
12
14
4
3
-
-
1
5
1
58
165
105
313
Ralstonia solanacearum
AL646052
5116
44
22
12
10
4
2
-
-
1
3
1
62
161
100
314
Rhodoferax ferrireducens
CP000267
4418
63
24
25
30
-
14
-
1
-
7
3
69
236
134
315
Thiobacillus denitrificans
CP000116
2827
31
7
15
16
4
2
-
2
-
6
2
32
117
143
316
Verminephrobacter eiseniae
CP000542
4947
19
3
4
4
1
-
-
-
-
2
2
23
57
51
  Gamma-proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
317
Acidithiobacillus ferrooxidans
CP001132
2826
13
-
-
3
-
-
-
-
-
1
3
16
37
86
318
Acinetobacter baumannii
CP000521
3368
17
1
7
3
2
-
-
2
-
3
1
18
51
84
319
Acinetobacter sp. ADP1
CR543861
3325
18
-
7
3
1
-
-
1
-
6
1
18
55
89
320
Actinobacillus pleuropneumoniae
CP000569
2012
5
-
-
-
-
-
1
-
-
1
-
5
12
64
321
Actinobacillus succinogenes
CP000746
2079
5
-
-
-
-
-
1
-
-
1
-
5
12
60
322
Aeromonas hydrophila
CP000462
4122
46
43
32
13
10
14
1
-
1
4
2
48
214
136
323
Aeromonas salmonicida
CP000644
4437
34
33
31
10
7
10
1
-
1
2
2
38
169
117
324
Alcanivorax borkumensis
AM286690
2755
30
1
9
3
-
1
-
2
-
6
1
29
82
128
325
Aliivibrio salmonicida
FM178379
3911
29
15
25
6
5
5
1
-
1
5
4
30
125
114
326
Alkalilimnicola ehrlichei
CP000453
2865
25
5
23
18
3
1
-
1
-
3
2
32
113
140
327
Alteromonas macleodii
CP001103
4072
54
16
25
22
5
7
1
2
-
4
3
52
191
131
328
Baumannia cicadellinicola
CP000238
595
-
-
-
-
-
-
-
-
-
-
-
-
0
0
329
Buchnera aphidicola
BA000003
574
-
-
-
-
-
-
-
-
-
-
-
-
0
0
330
Candidatus Blochmannia floridanus
BX248583
583
-
-
-
-
-
-
-
-
-
1
-
-
1
0
331
Candidatus Blochmannia pennsylvanicus
CP000016
610
-
-
-
-
-
-
-
-
-
1
-
-
1
0
332
Candidatus Carsonella ruddii
AP009180
182
-
-
-
-
-
-
-
-
-
-
-
-
0
0
333
Candidatus Ruthia magnifica
CP000488
976
2
-
-
-
-
-
-
-
-
2
1
3
8
116
334
Candidatus Vesicomyosocius okutanii
AP009247
937
2
-
-
-
-
-
-
-
-
2
1
3
8
120
335
Cellvibrio japonicus
CP000934
3754
38
16
20
21
3
5
1
3
-
6
7
36
157
130
336
Chromohalobacter salexigens
CP000285
3298
21
13
11
9
2
2
-
-
-
3
2
29
92
116
337
Citrobacter koseri
CP000822
5026
33
14
10
7
12
-
1
-
-
-
-
37
114
85
338
Colwellia psychrerythraea
CP000083
4910
56
23
34
26
5
3
-
-
-
9
2
59
217
119
339
Coxiella burnetii
AE016828
2046
7
-
-
-
-
-
-
1
-
4
-
8
20
87
340
Dichelobacter nodosus
CP000513
1280
6
1
-
-
1
-
-
-
-
1
-
9
16
123
341
Cronobacter sakazakii
CP000783
4434
26
26
12
9
12
-
1
-
-
2
2
33
124
101
342
Enterobacter sp. 638
CP000653
4240
30
18
16
10
10
1
1
-
-
-
-
29
115
102
343
Erwinia carotovora
BX950851
4472
28
36
13
4
7
1
1
-
1
2
1
28
122
100
344
Erwinia tasmaniensis
CU468135
3622
22
12
5
4
5
-
1
-
-
2
2
26
79
99
345
Escherichia coli K12
U00096
4132
30
5
12
7
10
-
1
-
-
2
-
32
99
97
346
Escherichia coli O157:H7
BA000007
5253
30
5
12
7
9
-
1
-
-
2
-
33
100
74
347
Escherichia fergusonii
CU928158
4266
29
3
12
8
8
-
1
-
-
2
-
36
102
95
348
Francisella novicida
CP000439
1719
2
-
-
2
-
-
-
-
-
1
-
2
8
59
349
Francisella philomiragia
CP000937
1915
3
-
-
-
-
-
-
-
-
1
-
4
9
54
350
Francisella tularensis
AJ749949
1804
2
-
-
-
-
-
-
-
-
1
-
2
5
31
351
Haemophilus ducreyi
AE017143
1717
1
-
-
-
-
-
1
-
-
1
-
3
6
45
352
Haemophilus influenzae
L42023
1711
4
-
-
-
-
-
1
-
-
1
-
6
12
80
353
Haemophilus somnus
CP000436
1792
1
-
-
-
-
-
1
-
-
2
-
3
7
48
354
Hahella chejuensis
CP000155
6778
80
35
31
33
6
9
1
4
-
20
12
87
318
106
355
Halorhodospira halophila
CP000544
2407
27
12
10
9
3
5
-
-
-
3
3
20
93
148
356
Idiomarina loihiensis
AE017340
2640
26
15
16
17
3
1
-
-
-
2
1
28
109
147
357
Klebsiella pneumoniae 342
CP000964
5768
32
-
14
7
12
1
1
-
-
3
1
32
102
65
358
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
CP000647
5187
33
-
13
6
14
1
1
-
-
1
-
34
102
76
359
Legionella pneumophila
AE017354
2942
12
-
8
11
3
-
-
5
-
5
-
12
56
103
360
Mannheimia succiniciproducens
AE016827
2384
5
-
-
-
-
-
1
-
-
1
-
5
12
47
361
Marinobacter aquaeolei
CP000514
4272
43
21
30
19
5
8
1
1
-
3
3
42
177
123
362
Marinomonas sp. MWYL1
CP000749
4439
51
51
42
15
8
6
-
1
1
3
4
51
237
134
363
Methylococcus capsulatus
AE017282
2959
17
2
5
11
1
1
-
-
-
3
5
18
63
108
364
Nitrosococcus oceani
CP000127
2974
19
1
2
12
-
1
-
1
-
1
4
23
64
108
365
Pasteurella multocida
AE004439
2015
9
-
-
-
-
-
1
-
-
1
-
9
20
89
366
Photobacterium profundum
CR354531
5480
53
39
22
10
6
2
1
-
1
8
2
54
198
104
367
Photorhabdus luminescens
BX470251
4683
18
2
-
-
-
-
1
-
-
1
1
20
43
43
368
Proteus mirabilis
AM942759
3662
18
9
1
-
-
-
1
-
1
1
1
21
53
78
369
Pseudoalteromonas atlantica
CP000388
4281
55
10
33
27
3
5
-
2
-
6
3
48
192
127
370
Pseudoalteromonas haloplanktis
CR954246
3486
38
14
21
17
7
3
-
-
-
4
1
38
143
132
371
Pseudomonas aeruginosa
AE004091
5567
63
26
17
16
6
3
1
1
-
8
6
64
210
105
372
Pseudomonas entomophila
CT573326
5134
61
32
19
19
2
-
1
-
-
6
4
64
208
113
373
Pseudomonas fluorescens
CP000076
6137
80
42
21
19
10
4
1
-
-
5
3
78
263
106
374
Pseudomonas mendocina
CP000680
4594
51
30
28
20
4
6
1
1
-
5
6
52
204
123
375
Pseudomonas putida
AE015451
5350
67
27
19
17
3
2
1
-
-
5
3
67
211
109
376
Pseudomonas stutzeri
CP000304
4128
66
33
19
14
3
2
1
1
-
6
7
47
199
132
377
Pseudomonas syringae
AE016853
5608
69
48
16
19
2
1
1
-
-
6
4
63
231
109
378
Psychrobacter arcticus
CP000082
2120
13
1
-
1
-
-
-
-
-
3
1
14
33
109
379
Psychrobacter cryohalolentis
CP000323
2511
18
1
1
2
-
-
-
1
-
5
2
17
47
110
380
Psychrobacter sp. PRwf-1
CP000713
2385
13
1
-
-
-
-
-
-
-
4
1
14
30
92
381
Psychromonas ingrahamii
CP000510
3541
24
-
23
32
5
5
1
-
-
6
3
23
123
123
382
Saccharophagus degradans
CP000282
4008
61
13
25
18
2
9
1
3
-
11
8
53
204
136
383
Salmonella enterica serovar Paratyphi
CP000026
4093
26
6
6
7
8
-
1
-
-
1
-
33
88
92
384
Salmonella enterica serovar Typhi
AL513382
4758
30
6
5
7
9
-
1
-
-
3
1
32
94
80
385
Salmonella typhimurium LT2
AE006468
4527
32
9
5
7
8
-
1
-
-
1
-
33
96
86
386
Serratia proteamaculans
CP000826
4942
36
6
11
5
5
-
-
-
-
2
1
38
104
82
387
Shewanella amazonensis
CP000507
3645
45
29
44
24
5
8
1
1
-
3
-
48
208
147
388
Shewanella baltica
CP000563
4489
41
39
35
24
6
11
-
1
1
4
1
45
207
126
389
Shewanella denitrificans
CP000302
3754
28
19
34
22
4
8
-
1
-
7
1
35
159
130
390
Shewanella frigidimarina
CP000447
4029
39
24
33
30
-
8
1
1
1
6
3
42
190
132
391
Shewanella halifaxensis
CP000931
4278
36
18
31
18
4
5
1
1
1
5
4
42
166
119
392
Shewanella loihica
CP000606
3859
44
23
32
21
2
9
1
1
1
3
-
48
185
135
393
Shewanella oneidensis
AE014299
4467
46
26
30
22
5
9
1
1
1
7
1
48
197
124
394
Shewanella pealeana
CP000851
4241
38
19
30
17
4
5
1
1
1
5
4
44
166
120
395
Shewanella piezotolerans
CP000472
4933
43
23
27
17
3
6
1
1
1
6
4
47
178
109
396
Shewanella putrefaciens
CP000681
3972
39
37
21
21
4
6
1
1
1
3
-
44
177
130
397
Shewanella sediminis
CP000821
4497
57
37
53
21
2
18
1
1
1
5
3
58
256
136
398
Shewanella sp. ANA-3
CP000469
4360
44
36
36
23
5
9
1
1
1
4
2
45
207
129
399
Shewanella sp. MR-4
CP000446
3924
45
32
37
24
4
9
1
1
1
5
1
46
206
139
400
Shewanella sp. MR-7
CP000444
4014
43
33
32
23
5
6
1
1
1
5
1
45
196
134
401
Shewanella sp. W3-18-1
CP000503
4044
37
38
21
22
5
5
1
1
1
5
1
43
179
129
402
Shewanella woodyi
CP000961
4880
56
26
45
22
4
15
1
1
-
7
3
54
231
123
403
Shigella boydii
CP000036
4284
26
2
6
5
6
-
1
-
-
2
-
31
79
82
404
Shigella dysenteriae
CP000034
4497
22
2
7
2
5
-
1
-
-
2
-
27
68
70
405
Shigella flexneri
AE005674
4441
25
4
6
2
6
-
1
-
-
2
-
27
73
75
406
Shigella sonnei
CP000038
4461
29
4
10
5
5
-
1
-
-
1
-
31
86
82
407
Sodalis glossinidius
AP008232
2516
10
-
2
1
1
-
1
-
-
2
-
15
32
90
408
Stenotrophomonas maltophilia
AM743169
4386
60
12
18
10
3
2
-
1
-
4
1
62
173
119
409
Thiomicrospira crunogena
CP000109
2196
20
14
24
17
6
3
-
-
-
2
1
22
109
165
410
Vibrio cholerae
AE003852
3835
43
45
31
10
12
9
1
-
-
1
1
43
196
139
411
Vibrio fischeri
CP000020
3802
36
43
29
9
10
2
1
-
-
5
2
36
173
133
412
Vibrio harveyi
CP000789
6055
42
25
31
12
14
5
-
-
1
4
1
45
178
88
413
Vibrio parahaemolyticus
BA000031
4832
50
30
28
16
13
5
1
-
1
6
2
52
204
118
414
Vibrio splendidus
FM954972
4431
49
31
27
18
7
10
1
-
-
5
1
47
192
123
415
Vibrio vulnificus
AE016795
5024
51
52
46
20
13
13
1
-
-
4
3
50
253
124
416
Wigglesworthia glossinidia
BA000021
617
-
-
-
-
-
-
-
-
-
1
-
1
2
92
417
Xanthomonas axonopodis
AE008923
4427
61
21
20
10
4
3
-
-
-
9
4
49
182
121
418
Xanthomonas campestris
AE008922
4181
55
20
21
10
4
3
-
-
-
5
3
49
171
123
419
Xanthomonas oryzae
AE013598
4637
42
10
12
10
2
3
-
-
-
7
3
42
131
100
420
Xylella fastidiosa
AE003849
2832
14
1
1
2
1
1
-
-
-
2
1
16
39
88
421
Yersinia enterocolitica
AM286415
4051
30
12
10
5
6
1
-
-
2
3
-
34
102
101
422
Yersinia pestis
AL590842
4067
23
6
2
3
3
-
1
-
1
3
-
31
73
83
423
Yersinia pseudotuberculosis
BX936398
4038
26
8
3
3
3
1
1
-
1
4
-
28
78
87
  Delta-proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
424
Anaeromyxobacter dehalogenans
CP000251
4346
85
19
10
-
1
5
-
1
-
19
3
87
230
134
425
Anaeromyxobacter sp. Fw109-5
CP000769
4466
101
12
10
-
1
5
-
1
-
23
4
87
243
134
426
Anaeromyxobacter sp. K
CP001131
4457
90
19
10
-
1
4
-
-
-
20
3
88
235
133
427
Bdellovibrio bacteriovorus
BX842601
3587
49
20
5
-
1
6
-
4
-
5
4
39
133
126
428
Desulfatibacillum alkenivorans
CP001322
5252
131
21
23
2
2
11
-
8
1
12
17
83
310
130
429
Desulfococcus oleovorans
CP000859
3265
40
11
17
1
2
8
-
-
1
11
2
56
144
139
430
Desulfotalea psychrophila
CR522870
3234
31
21
20
3
1
10
-
1
-
4
6
26
123
132
431
Desulfovibrio desulfuricans
CP000112
3865
49
30
24
8
2
14
-
-
1
1
4
55
179
133
432
Desulfovibrio vulgaris
AE017285
3531
64
28
17
9
1
14
-
-
1
1
2
64
201
148
433
Geobacter bemidjiensis
CP001124
4018
126
35
14
7
1
13
-
1
-
2
5
92
295
154
434
Geobacter lovleyi
CP001089
3685
97
29
30
13
4
12
-
2
-
3
6
82
278
160
435
Geobacter metallireducens
CP000148
3634
83
18
13
6
1
12
-
2
-
2
6
63
206
147
436
Geobacter sulfurreducens
AE017180
3446
92
33
20
8
1
10
-
-
-
1
3
74
242
160
437
Geobacter uraniireducens
CP000698
4357
97
26
17
1
2
15
-
1
1
3
7
97
265
141
438
Lawsonia intracellularis
AM180252
1344
5
3
2
-
-
1
-
-
-
-
1
9
21
132
439
Myxococcus xanthus
CP000113
7331
140
21
18
-
2
6
-
12
-
102
5
120
426
113
440
Pelobacter carbinolicus
CP000142
3353
34
15
21
15
-
5
-
1
-
1
3
40
135
134
441
Pelobacter propionicus
CP000482
3576
74
21
20
10
2
9
-
-
-
3
3
52
194
145
442
Sorangium cellulosum
AM746676
9384
149
5
8
1
-
2
-
19
-
323
29
113
642
109
443
Syntrophobacter fumaroxidans
CP000478
4064
73
1
7
2
-
6
-
6
-
9
6
59
169
126
444
Syntrophus aciditrophicus
CP000252
3168
26
5
7
-
-
7
-
3
-
-
3
29
80
113
  Epsilon-proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
445
Arcobacter butzleri
CP000361
2259
37
29
14
10
1
6
-
1
-
1
-
40
136
173
446
Campylobacter concisus
CP000792
1985
11
9
5
6
-
-
-
-
-
-
-
13
45
131
447
Campylobacter curvus
CP000767
1931
13
8
5
6
-
-
-
-
-
-
-
15
47
136
448
Campylobacter fetus
CP000487
1719
12
14
6
3
1
-
-
-
-
-
-
14
50
151
449
Campylobacter hominis
CP000776
1687
8
-
-
1
-
-
-
-
-
-
-
8
16
96
450
Campylobacter jejuni
AL111168
1623
7
10
1
-
-
-
-
-
-
-
-
10
28
127
451
Helicobacter acinonychis
AM260522
1660
4
4
-
-
-
-
-
-
-
-
-
9
17
100
452
Helicobacter hepaticus
AE017125
1875
5
9
1
-
-
-
-
-
-
-
-
10
25
107
453
Helicobacter pylori
AE000511
1576
4
4
-
-
-
-
-
-
-
1
1
9
19
111
454
Nitratiruptor sp. SB155-2
AP009178
1843
15
8
12
22
-
-
-
-
-
3
2
17
80
167
455
Sulfurimonas denitrificans
CP000153
2097
37
13
22
16
-
3
-
1
-
1
1
40
134
180
456
Sulfurovum sp. NBC37-1
AP009179
2438
30
-
6
12
1
-
-
1
-
2
2
27
81
140
457
Wolinella succinogenes
BX571656
2044
39
31
12
9
3
2
-
1
-
2
3
37
139
184
  Unclassified proteobacteria
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
458
Magnetococcus sp. MC-1
CP000471
3716
100
33
25
17
1
16
-
13
-
7
10
57
279
160
  Spirochaetes
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
459
Borrelia afzelii
CP000395
1215
4
5
1
-
1
1
-
-
1
-
-
5
19
137
460
Borrelia burgdorferi
AE001115
1639
4
5
1
-
1
1
-
-
1
-
-
4
17
101
461
Borrelia duttonii
CP000976
1305
4
5
1
-
1
1
-
-
1
-
1
5
19
130
462
Borrelia garinii
CP000013
932
4
5
1
-
1
1
-
-
1
-
-
5
18
161
463
Borrelia hermsii
CP000048
819
4
5
1
-
1
1
-
-
1
-
1
5
19
176
464
Borrelia recurrentis
CP000993
990
4
5
1
-
1
1
-
-
1
-
1
5
19
157
465
Borrelia turicatae
CP000049
818
4
5
1
-
1
1
-
-
1
-
1
5
20
179
466
Leptospira biflexa
CP000777
3600
65
26
6
5
4
3
-
25
-
1
39
37
215
150
467
Leptospira borgpetersenii
CP000348
2945
32
9
6
-
4
3
-
9
-
5
19
23
110
136
468
Leptospira interrogans
AE010300
4727
47
13
10
3
5
2
-
18
-
4
22
28
152
105
469
Treponema denticola
AE017226
2767
7
20
7
2
-
4
-
9
-
-
4
10
63
115
470
Treponema pallidum
AE000520
1036
1
4
1
-
-
3
-
1
-
-
3
3
16
144
  Tenericutes
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
471
Acholeplasma laidlawii
CP000896
1380
2
-
9
4
1
1
-
1
-
-
-
3
21
129
472
Aster yellows witches'-broom phytoplasma
CP000061
693
-
-
-
-
-
-
-
-
-
-
-
-
0
0
473
Candidatus Phytoplasma australiense
AM422018
696
-
-
-
-
-
-
-
-
-
-
-
-
0
0
474
Candidatus Phytoplasma mali
CU469464
479
-
-
-
-
-
-
-
-
-
-
-
-
0
0
475
Mesoplasma florum
AE017263
682
-
-
-
-
-
-
-
-
-
1
1
-
2
82
476
Mycoplasma agalactiae
CU179680
742
-
-
-
-
-
-
-
-
-
-
1
-
1
0
477
Mycoplasma arthritidis
CP001047
631
-
-
-
-
-
-
-
-
-
1
1
-
2
90
478
Mycoplasma capricolum
CP000123
812
-
-
-
-
-
-
-
-
-
1
2
-
3
85
479
Mycoplasma gallisepticum
AE015450
726
-
-
-
-
-
-
-
-
-
1
1
-
2
76
480
Mycoplasma genitalium
L43967
484
-
-
-
-
-
-
-
-
-
1
1
-
2
116
481
Mycoplasma hyopneumoniae
AE017332
691
-
-
-
-
-
-
-
-
-
-
-
-
0
0
482
Mycoplasma mobile
AE017308
633
-
-
-
-
-
-
-
-
-
2
1
-
3
110
483
Mycoplasma mycoides
BX293980
1016
-
-
-
-
-
-
-
-
-
1
1
-
2
42
484
Mycoplasma penetrans
BA000026
1037
-
-
-
-
-
-
-
-
-
2
1
-
3
61
485
Mycoplasma pneumoniae
U00089
689
-
-
-
-
-
-
-
-
-
1
1
-
2
81
486
Mycoplasma pulmonis
AL445566
782
-
-
-
-
-
-
-
-
-
1
1
-
2
68
487
Mycoplasma synoviae
AE017245
672
-
-
-
-
-
-
-
-
-
1
1
-
2
84
488
Onion yellows phytoplasma
AP006628
754
-
-
-
-
-
-
-
-
-
-
-
-
0
0
489
Ureaplasma parvum
AF222894
614
-
-
-
-
-
-
-
-
-
1
1
-
2
93
490
Ureaplasma urealyticum
CP001184
646
-
-
-
-
-
-
-
-
-
1
1
-
2
88
  Thermotogae
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
491
Fervidobacterium nodosum
CP000771
1750
10
8
14
1
-
8
-
1
-
-
4
9
55
154
492
Petrotoga mobilis
CP000879
1898
8
11
4
1
-
2
-
-
-
-
-
8
34
121
493
Thermosipho africanus
CP001185
1913
9
10
14
1
-
12
-
1
-
-
2
10
56
146
494
Thermosipho melanesiensis
CP000716
1879
9
14
13
1
-
12
-
1
-
-
4
11
64
154
495
Thermotoga lettingae
CP000812
2040
8
6
10
-
1
9
-
-
-
-
2
9
46
129
496
Thermotoga maritima
AE000512
1858
8
7
8
-
-
10
-
-
-
-
2
8
43
135
497
Thermotoga petrophila
CP000702
1785
7
6
8
-
-
9
-
-
-
-
2
8
41
137
498
Thermotoga sp. RQ2
CP000969
1819
8
6
8
-
-
7
-
-
-
-
2
8
39
133
  Verrucomicrobia
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
499
Akkermansia muciniphila
CP001071
2138
5
-
-
-
-
-
-
-
-
-
3
5
13
61
500
Methylacidiphilum infernorum
CP000975
2472
9
-
-
-
-
-
-
-
-
-
1
11
21
71
501
Opitutus terrae
CP001032
4612
117
14
1
-
-
1
-
4
-
9
5
79
229
128
  Other bacterial phyla
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
502
Fusobacterium nucleatum
AE009951
2066
7
-
-
-
-
-
-
1
-
-
1
8
17
78
503
Rhodopirellula baltica
BX119912
7325
46
-
7
2
1
6
-
3
1
60
3
52
181
70
504
Thermodesulfovibrio yellowstonii
CP001147
2033
32
11
5
-
2
5
-
3
-
1
-
35
92
164
  Archaea
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
  Crenarchaeota
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
505
Aeropyrum pernix
BA000002
1841
-
-
-
-
-
-
-
-
0*
5
-
-
6
38
506
Caldivirga maquilingensis
CP000852
1963
-
-
-
-
-
-
-
-
0*
5
-
-
6
31
507
Cenarchaeum symbiosum
DP000238
2017
-
-
-
-
-
-
-
2
-
5
1
-
6
29
508
Desulfurococcus kamchatkensis
CP001140
1471
-
-
-
-
-
-
-
-
0*
5
-
-
6
60
509
Hyperthermus butylicus
CP000493
1602
-
-
-
-
-
-
-
-
0*
5
-
-
7
59
510
Ignicoccus hospitalis
CP000816
1434
-
-
-
-
-
-
-
-
0*
6
-
-
7
70
511
Metallosphaera sedula
CP000682
2256
-
-
-
-
-
-
-
-
0*
10
-
-
11
48
512
Nitrosopumilus maritimus
CP000866
1795
9
-
-
-
-
-
-
4
-
-
-
10
19
103
513
Pyrobaculum aerophilum
AE009441
2605
-
-
-
-
-
-
-
-
0*
5
-
-
6
3
514
Pyrobaculum arsenaticum
CP000660
2299
-
-
-
-
-
-
-
-
0*
4
-
-
6
16
515
Pyrobaculum calidifontis
CP000561
2149
-
-
-
-
-
-
-
-
0*
4
-
-
6
22
516
Pyrobaculum islandicum
CP000504
1978
-
-
-
-
-
-
-
-
0*
5
-
-
6
31
517
Staphylothermus marinus
CP000575
1570
-
-
-
-
-
-
-
-
0*
5
-
-
6
54
518
Sulfolobus acidocaldarius
CP000077
2223
-
-
-
-
-
-
-
-
0*
10
-
-
11
49
519
Sulfolobus solfataricus
AE006641
2977
-
-
-
-
-
-
-
-
0*
8
-
-
9
10
520
Sulfolobus tokodaii
BA000023
2825
-
-
-
-
-
-
-
-
0*
12
-
-
13
34
521
Thermofilum pendens
CP000505
1876
-
-
-
-
-
-
-
-
0*
4
-
-
5
27
522
Thermoproteus neutrophilus
CP001014
1966
-
-
-
-
-
-
-
-
0*
5
-
-
7
39
  Euryarchaeaota
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
523
Archaeoglobus fulgidus
AE000782
2420
14
2
-
-
-
-
-
-
0*
3
-
10
30
91
524
Candidatus Methanoregula boonei
CP000780
2450
54
4
-
-
-
-
-
-
0*
10
6
40
113
156
525
Haloarcula marismortui
AY596297
4240
59
17
-
-
-
-
-
-
0*
8
1
24
110
100
526
Halobacterium sp. NRC-1
AE004437
2622
13
17
-
-
-
-
-
-
0*
5
-
5
41
99
527
Haloquadratum walsbyi
AM180088
2646
7
-
-
-
-
-
-
-
0*
5
-
3
16
51
528
Methanobrevibacter smithii
CP000678
1793
-
-
-
-
-
-
-
-
0*
3
-
-
4
20
529
Methanocaldococcus jannaschii
L77117
1786
-
-
-
-
-
-
-
-
0*
4
-
-
5
32
530
Methanococcoides burtonii
CP000300
2273
30
1
-
-
-
-
-
-
0*
5
-
14
51
124
531
Methanococcus aeolicus
CP000743
1490
1
-
-
-
-
-
-
-
0*
4
-
1
8
73
532
Methanococcus maripaludis
BX950229
1722
3
4
-
-
-
-
-
-
0*
4
-
3
15
90
533
Methanococcus vannielii
CP000742
1678
5
4
-
-
-
-
-
-
0*
4
-
3
22
112
534
Methanocorpusculum labreanum
CP000559
1739
1
-
-
-
-
-
-
-
0*
5
1
1
10
69
535
Methanoculleus marisnigri
CP000562
2489
28
2
-
-
-
-
-
-
-
5
2
6
44
107
536
Methanopyrus kandleri
AE009439
1687
-
-
-
-
-
-
-
0*
0*
5
-
-
6
47
537
Methanosaeta thermophila
CP000477
1696
7
-
-
-
-
-
-
-
0*
4
1
4
16
95
538
Methanosarcina acetivorans
AE010299
4540
53
2
-
-
-
-
-
1
0*
5
-
15
77
75
539
Methanosarcina barkeri
CP000099
3625
26
1
-
-
-
-
-
-
0*
5
-
11
44
70
540
Methanosarcina mazei
AE008384
3371
33
3
-
-
-
-
-
-
0*
4
-
14
55
88
541
Methanosphaera stadtmanae
CP000102
1534
-
-
-
-
-
-
-
0*
0*
3
-
-
4
36
542
Methanospirillum hungatei
CP000254
3139
76
27
-
-
-
-
-
-
0*
9
6
56
175
153
543
Methanothermobacter thermautotrophicus
AE000666
1873
16
-
-
-
-
-
-
0*
0*
3
-
7
27
111
544
Natronomonas pharaonis
CR936257
2822
33
19
-
-
-
-
-
-
0*
6
-
10
69
117
545
Picrophilus torridus
AE017261
1535
-
-
-
-
-
-
-
-
-
5
-
-
5
47
546
Pyrococcus abyssi
AL096836
1896
1
5
-
-
-
-
-
-
0*
4
-
2
14
77
547
Pyrococcus furiosus
AE009950
2125
-
-
-
-
-
-
-
-
0*
5
-
-
7
31
548
Pyrococcus horikoshii
BA000001
1955
1
5
-
-
-
-
-
-
0*
4
-
2
14
74
549
Thermococcus kodakarensis
AP006878
2306
-
5
-
-
-
-
-
-
0*
4
-
2
13
54
550
Thermococcus onnurineus
CP000855
1976
1
4
-
-
-
-
-
-
0*
3
-
2
13
69
551
Thermoplasma acidophilum
AL139299
1481
-
-
-
-
-
-
-
-
-
4
-
-
4
39
552
Thermoplasma volcanium
BA000011
1499
-
-
-
-
-
-
-
-
-
4
1
-
5
49
553
Uncultured methanogenic archaeon RC-I
AM114193
3103
45
3
1
-
-
1
-
-
0*
8
-
14
73
111
  Other archaea
GenBank
All
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
Total
IQ
554
Candidatus Korarchaeum cryptofilum
CP000968
1602
-
-
-
-
-
-
-
-
0*
-
-
-
1
0
555
Nanoarchaeum equitans
AE017199
535
-
-
-
-
-
-
-
-
-
3
-
-
3
127
No.
Organism
GenBank
All prot.
HisK
MCP
GGDEF
GGDEF
+EAL
EAL
HD-GYP
AC1
AC3
ACIV
STYK
PP2C
RRs
All total
IQ
  Total no.    
15883
4735
4001
2660
952
1198
65
866
147
3356
1460
14986
 
 
  % total    
31.6%
9.4%
8.0%
5.3%
1.9%
2.4%
0.1%
1.7%
0.3%
6.7%
2.9%
29.8%
 
 

a The numbers in the table are linked to protein lists, which are further linked to RefSeq and UniProt database entries, BLink outputs, and CDD and Pfam domain architectures. Numbers with asterisks indicate the presence of proteins with highly divergent and/or truncated domains, not included in the total count but listed at the end of the each protein list. Comments and corrections are welcome.