Missing outcomes in randomized trials: addressing the dilemma
- PMID: 19946393
- PMCID: PMC2765768
Missing outcomes in randomized trials: addressing the dilemma
Conflict of interest statement
Competing interests: None declared.
Comment on
-
Have last-observation-carried-forward analyses caused us to favour more toxic dementia therapies over less toxic alternatives? A systematic review.Open Med. 2009 Mar 24;3(2):e31-50. Open Med. 2009. PMID: 19946392 Free PMC article.
Similar articles
-
Addressing missing participant outcome data in dental clinical trials.J Dent. 2015 Jun;43(6):605-18. doi: 10.1016/j.jdent.2015.03.007. Epub 2015 Mar 31. J Dent. 2015. PMID: 25837533 Review.
-
Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals.Clin Trials. 2004;1(4):368-76. doi: 10.1191/1740774504cn032oa. Clin Trials. 2004. PMID: 16279275 Review.
-
A systematic survey of the methods literature on the reporting quality and optimal methods of handling participants with missing outcome data for continuous outcomes in randomized controlled trials.J Clin Epidemiol. 2017 Aug;88:67-80. doi: 10.1016/j.jclinepi.2017.05.016. Epub 2017 Jun 1. J Clin Epidemiol. 2017. PMID: 28579378 Review.
-
A systematic survey on reporting and methods for handling missing participant data for continuous outcomes in randomized controlled trials.J Clin Epidemiol. 2017 Aug;88:57-66. doi: 10.1016/j.jclinepi.2017.05.017. Epub 2017 Jun 3. J Clin Epidemiol. 2017. PMID: 28583378 Review.
-
Simple adjustments for randomized trials with nonrandomly missing or censored outcomes arising from informative covariates.Biostatistics. 2006 Jan;7(1):29-40. doi: 10.1093/biostatistics/kxi038. Epub 2005 May 27. Biostatistics. 2006. PMID: 15923407
Cited by
-
A Dance Movement Psychotherapy Intervention for the Wellbeing of Children With an Autism Spectrum Disorder: A Pilot Intervention Study.Front Psychol. 2021 Jul 19;12:588418. doi: 10.3389/fpsyg.2021.588418. eCollection 2021. Front Psychol. 2021. PMID: 34349692 Free PMC article.
-
Evaluator-blinded trial evaluating nurse-led immunotherapy DEcision Coaching In persons with relapsing-remitting Multiple Sclerosis (DECIMS) and accompanying process evaluation: study protocol for a cluster randomised controlled trial.Trials. 2015 Mar 21;16:106. doi: 10.1186/s13063-015-0611-7. Trials. 2015. PMID: 25872529 Free PMC article. Clinical Trial.
-
Analysis of longitudinal data from animals with missing values using SPSS.Nat Protoc. 2016 Jun;11(6):1112-29. doi: 10.1038/nprot.2016.048. Epub 2016 May 19. Nat Protoc. 2016. PMID: 27196723 Free PMC article.
-
Evidence-Based, Patient-Centered Treatment of Erythema Migrans in the United States.Antibiotics (Basel). 2021 Jun 22;10(7):754. doi: 10.3390/antibiotics10070754. Antibiotics (Basel). 2021. PMID: 34206379 Free PMC article.
-
Awareness on causes, consequences and preventive measures of obesity among urban married women in India.Int J Med Public Health. 2013 Oct;3(4):293-302. doi: 10.4103/2230-8598.123476. Int J Med Public Health. 2013. PMID: 28856116 Free PMC article.
References
-
- Moher D, Schulz K F, Altman D CONSORT Group. The CONSORT Statement: Revised recommendations for improving the quality of reports of parallel-group randomized trials. JAMA. 2001;285(15):1987–1991. http://jama.ama-assn.org/cgi/content/full/285/15/1987. - PubMed
-
- Montori V M, Guyatt G H. Intention-to-treat principle. CMAJ. 2001;165(10):1339–41. http://www.cmaj.ca/cgi/pmidlookup?view=long&pmid=11760981. - PMC - PubMed
-
- Altman Douglas G, Bland J Martin. Missing data. BMJ. 7590;334(7590):424. doi: 10.1136/bmj.38977.682025.2C. projects/linkout/nsh/nsh_display.cgi?PrId=5914&PmId=17322261&Code=tu&JrI.... - DOI - PMC - PubMed
-
- Wood Angela M, White Ian R, Thompson Simon G. Are missing outcome data adequately handled? A review of published randomized controlled trials in major medical journals. Clin Trials. 2004;1(4):368–376. - PubMed
LinkOut - more resources
Full Text Sources