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Select item 119174941.

Multiplexed glycan immunofluorescence identification of pancreatic cancer cell subpopulations in both tumor and blood samples

Braelyn Binkowski, Zachary Klamer, ChongFeng Gao, Ben Staal, Anna Repesh, Hoang-Le Tran, David M. Brass, Pamela Bartlett, Steven Gallinger, Maria Blomqvist, J. Bradley Morrow, Peter Allen, Chanjuan Shi, Aatur Singhi, Randall Brand, Ying Huang, Galen Hostetter, Brian B. Haab

Sci Adv. 2025 Mar 7; 11(10): eadt0029. Published online 2025 Mar 7. doi: 10.1126/sciadv.adt0029

PMCID:: PMC11917494

Article PDF–2.4M

Select item 119085072.

Long-term adhesion durability revealed through a rheological paradigm

Changhong Linghu, Rui Wu, Yuqing Chen, Yulin Huang, Young-Jae Seo, Hua Li, Guannan Wang, Huajian Gao, K. Jimmy Hsia

Sci Adv. 2025 Mar 14; 11(11): eadt3957. Published online 2025 Mar 14. doi: 10.1126/sciadv.adt3957

PMCID:: PMC11908507

Article PDF–2.8M

Select item 119085043.

Broadband uniform-efficiency OAM-mode detector

Suman Karan, Martin P. Van Exter, Anand K. Jha

Sci Adv. 2025 Mar 14; 11(11): eadq7201. Published online 2025 Mar 14. doi: 10.1126/sciadv.adq7201

PMCID:: PMC11908504

Article PDF–2.4M

Select item 119085024.

Spraying of water microdroplets forms luminescence and causes chemical reactions in surrounding gas

Yifan Meng, Yu Xia, Jinheng Xu, Richard N. Zare

Sci Adv. 2025 Mar 14; 11(11): eadt8979. Published online 2025 Mar 14. doi: 10.1126/sciadv.adt8979

PMCID:: PMC11908502

Article PDF–3.3M

Select item 119085005.

Biological age prediction using a DNN model based on pathways of steroidogenesis

Qiuyi Wang, Zi Wang, Kenji Mizuguchi, Toshifumi Takao

Sci Adv. 2025 Mar 14; 11(11): eadt2624. Published online 2025 Mar 14. doi: 10.1126/sciadv.adt2624

PMCID:: PMC11908500

Article PDF–3.3M

Select item 119084976.

Ectopic expression of testis-specific transcription elongation factor in driving cancer

Bin Zheng, Marta Iwanaszko, Shimaa Hassan AbdelAziz Soliman, Yukitomo Ishi, Sarah Gold, Ruxuan Qiu, Benjamin Charles Howard, Madhurima Das, Zibo Zhao, Rintaro Hashizume, Lu Wang, Ali Shilatifard

Sci Adv. 2025 Mar 14; 11(11): eads4200. Published online 2025 Mar 14. doi: 10.1126/sciadv.ads4200

PMCID:: PMC11908497

Article PDF–2.8M

Select item 119084957.

Protein misfolding involving entanglements provides a structural explanation for the origin of stretched-exponential refolding kinetics

Yang Jiang, Yingzi Xia, Ian Sitarik, Piyoosh Sharma, Hyebin Song, Stephen D. Fried, Edward P. O’Brien

Sci Adv. 2025 Mar 14; 11(11): eads7379. Published online 2025 Mar 14. doi: 10.1126/sciadv.ads7379

PMCID:: PMC11908495

Article PDF–4.2M

Select item 119084938.

An enzymatic cleavage-triggered minimally invasive nanosensor for urine-based detection of early atherosclerosis

Zhina Wu, Rui Liu, Jianai Chen, Xueying Cai, Jingzheng Yi, Jiasi Wang, Di Wang, Min Hu

Sci Adv. 2025 Mar 14; 11(11): eadu7614. Published online 2025 Mar 14. doi: 10.1126/sciadv.adu7614

PMCID:: PMC11908493

Article PDF–2.5M

Select item 119084909.

Assessing E. coli levels in surface soils of informal settlements using boot sock and standard grab methods

Lamiya Bata, Rebekah Henry, S. Fiona Barker, John Boyce, Fiona Lynch, Silvia Rosovoa Vilsoni, Autiko Tela, Revoni Vamosi, Ruzka R. Taruc, Andi Zulkifli Agussalim, Maghfira Saifuddaolah, Zainal Handis, David McCarthy, Karin Leder, RISE Consortium

Sci Adv. 2025 Mar 14; 11(11): eadq9869. Published online 2025 Mar 14. doi: 10.1126/sciadv.adq9869

PMCID:: PMC11908490

Article PDF–1.0M

Select item 1190848710.

Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy

Eun Young Jeon, Yejin Kwak, Hyeji Kang, Hanbyeol Kim, Se Young Jin, Soojin Park, Ryeo Gyeong Kim, Dayoung Ko, Jae-Kyung Won, Anna Cho, Inkyung Jung, Chul-Hwan Lee, Jeongbin Park, Hyun-Young Kim, Jong-Hee Chae, Murim Choi

Sci Adv. 2025 Mar 14; 11(11): eadr4443. Published online 2025 Mar 14. doi: 10.1126/sciadv.adr4443

PMCID:: PMC11908487

Article PDF–12M

Select item 1190848411.

PseudoSorter: A self-supervised spike sorting approach applied to reveal Tau-induced reductions in neuronal activity

Marius Brockhoff, Jakob Träuble, Sagnik Middya, Tanja Fuchsberger, Ana Fernandez-Villegas, Amberley Stephens, Miranda Robbins, Wenyue Dai, Belquis Haider, Sulay Vora, Nino F. Läubli, Clemens F. Kaminski, George G. Malliaras, Ole Paulsen, Gabriele S. Kaminski Schierle

Sci Adv. 2025 Mar 14; 11(11): eadr4155. Published online 2025 Mar 14. doi: 10.1126/sciadv.adr4155

PMCID:: PMC11908484

Article PDF–4.1M

Select item 1190848012.

Random encounters dominate water-water interactions at supercritical conditions

Katja Mauelshagen, Philipp Schienbein, Inga Kolling, Gerhard Schwaab, Dominik Marx, Martina Havenith

Sci Adv. 2025 Mar 14; 11(11): eadp8614. Published online 2025 Mar 14. doi: 10.1126/sciadv.adp8614

PMCID:: PMC11908480

Article PDF–2.1M

Select item 1190847413.

Pigment removal from reverse-printed laminated flexible films by solvent-targeted recovery and precipitation

Tianwei Yan, Charles Granger, Kevin L. Sánchez-Rivera, Panzheng Zhou, Steven Grey, Kevin Nelson, Fei Long, Ezra Bar-Ziv, Reid C. Van Lehn, Styliani Avraamidou, George W. Huber

Sci Adv. 2025 Mar 14; 11(11): eadt5841. Published online 2025 Mar 14. doi: 10.1126/sciadv.adt5841

PMCID:: PMC11908474

Article PDF–8.5M

Select item 1190846914.

The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection

Courtney Woolsey, Robert W. Cross, Victor C. Chu, Abhishek N. Prasad, Krystle N. Agans, Viktoriya Borisevich, Daniel J. Deer, Mack B. Harrison, Jasmine K. Martinez, Natalie S. Dobias, Karla A. Fenton, Tomas Cihlar, Anh-Quan Nguyen, Darius Babusis, Roy Bannister, Meghan S. Vermillion, Thomas W. Geisbert

Sci Adv. 2025 Mar 14; 11(11): eadw0659. Published online 2025 Mar 14. doi: 10.1126/sciadv.adw0659

PMCID:: PMC11908469

Article PDF–3.8M

Select item 1190088415.

Shaping early neural development by timed elevated tissue oxygen tension: Insights from multiomic analysis on human cerebral organoids

Yuan-Hsuan Liu, Meng-Ting Chung, Hsi-Chieh Lin, Tse-Ang Lee, Ya-Jen Cheng, Chien-Chang Huang, Hsiao-Mei Wu, Yi-Chung Tung

Sci Adv. 2025 Mar 14; 11(11): eado1164. Published online 2025 Mar 12. doi: 10.1126/sciadv.ado1164

PMCID:: PMC11900884

Article PDF–9.3M

Select item 1190088216.

Confronting Earth System Model trends with observations

Isla R. Simpson, Tiffany A. Shaw, Paulo Ceppi, Amy C. Clement, Erich Fischer, Kevin M. Grise, Angeline G. Pendergrass, James A. Screen, Robert C. J. Wills, Tim Woollings, Russell Blackport, Joonsuk M. Kang, Stephen Po-Chedley

Sci Adv. 2025 Mar 14; 11(11): eadt8035. Published online 2025 Mar 12. doi: 10.1126/sciadv.adt8035

PMCID:: PMC11900882

Article PDF–1.3M

Select item 1190088017.

EBAX-1/ZSWIM8 destabilizes miRNAs, resulting in transgenerational inheritance of a predatory trait

Shiela Pearl Quiobe, Ata Kalirad, Waltraud Röseler, Hanh Witte, Yinan Wang, Christian Rödelsperger, Ralf J. Sommer

Sci Adv. 2025 Mar 14; 11(11): eadu0875. Published online 2025 Mar 12. doi: 10.1126/sciadv.adu0875

PMCID:: PMC11900880

Article PDF–8.7M

Select item 1190087818.

Liquid-bodied antibiofilm robot with switchable viscoelastic response for biofilm eradication on complex surface topographies

Bonan Sun, Junjia Guo, Bo Hao, Yanfei Cao, Tony K. F. Chan, Mengmeng Sun, Joseph J. Y. Sung, Li Zhang

Sci Adv. 2025 Mar 14; 11(11): eadt8213. Published online 2025 Mar 12. doi: 10.1126/sciadv.adt8213

PMCID:: PMC11900878

Article PDF–9.8M

Select item 1190087619.

Spatial 3D genome organization reveals intratumor heterogeneity in primary glioblastoma samples

Qixuan Wang, Juan Wang, Radhika Mathur, Mark W. Youngblood, Qiushi Jin, Ye Hou, Lena Ann Stasiak, Yu Luan, Hengqiang Zhao, Stephanie Hilz, Chibo Hong, Susan M. Chang, Janine M. Lupo, Joanna J. Phillips, Joseph F. Costello, Feng Yue

Sci Adv. 2025 Mar 14; 11(11): eadn2830. Published online 2025 Mar 12. doi: 10.1126/sciadv.adn2830