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Items: 1 to 20 of 3449

1.
C21ORF2 mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis
Mathias De Decker, Pavol Zelina, Thomas G Moens, Jimmy Beckers, Matilde Contardo, Katarina Stoklund Dittlau, Evelien Van Schoor, Alicja Ronisz, Kristel Eggermont, Matthieu Moisse, Siddharthan Chandran, Jan H Veldink, Dietmar Rudolf Thal, Ludo Van Den Bosch, R Jeroen Pasterkamp, Philip Van Damme
Brain. 2025 Mar; 148(3): 803–816. Published online 2024 Dec 20. doi: 10.1093/brain/awae331
PMCID:
PMC11884758
ArticlePDF–1.3M
2.
Loss of glymphatic homeostasis in heart failure
Marios Kritsilis, Lotte Vanherle, Marko Rosenholm, René in ‘t Zandt, Yuan Yao, Kelley M Swanberg, Pia Weikop, Michael Gottschalk, Nagesh C Shanbhag, Jiebo Luo, Kimberly Boster, Maiken Nedergaard, Anja Meissner, Iben Lundgaard
Brain. 2025 Mar; 148(3): 985–1000. Published online 2024 Dec 18. doi: 10.1093/brain/awae411
PMCID:
PMC11884761
ArticlePDF–1.3M
3.
Optimizing rare disorder trials: a phase 1a/1b randomized study of KL1333 in adults with mitochondrial disease
Chiara Pizzamiglio, Renae J Stefanetti, Robert McFarland, Naomi Thomas, George Ransley, Matilda Hugerth, Alvar Grönberg, Sonia Simon Serrano, Eskil Elmér, Michael G Hanna, Magnus J Hansson, Gráinne S Gorman, Robert D S Pitceathly
Brain. 2025 Jan; 148(1): 39–46. Published online 2024 Dec 9. doi: 10.1093/brain/awae308
PMCID:
PMC11706290
ArticlePDF–804K
4.
Eighty-six billion and counting: do we know the number of neurons in the human brain?
Alain Goriely
Brain. 2025 Mar; 148(3): 689–691. Published online 2024 Nov 27. doi: 10.1093/brain/awae390
PMCID:
PMC11884752
ArticlePDF–307K
5.
Why inflammatory reductionism is a threat to psychiatry (and the rest of medicine)
Thomas A Pollak
Brain. 2025 Feb; 148(2): 349–351. Published online 2024 Nov 21. doi: 10.1093/brain/awae381
PMCID:
PMC11788218
ArticlePDF–275K
6.
Bridging the gaps between JCV infection models and human disease
Irene Cortese, C Sabrina Tan
Brain. 2024 Dec; 147(12): 3976–3978. Published online 2024 Nov 13. doi: 10.1093/brain/awae370
PMCID:
PMC11734337
ArticlePDF–365K
7.
Astroglial reactivity is a key modulator of Alzheimer’s disease pathological progression
Wiesje Pelkmans, Juan Domingo Gispert
Brain. 2024 Dec; 147(12): 3973–3975. Published online 2024 Nov 8. doi: 10.1093/brain/awae354
PMCID:
PMC11629679
ArticlePDF–266K
8.
Phase 2b program with sonlicromanol in patients with mitochondrial disease due to m.3243A>G mutation
Jan Smeitink, Just van Es, Brigitte Bosman, Mirian C H Janssen, Thomas Klopstock, Grainne Gorman, John Vissing, Gerrit Ruiterkamp, Chris J Edgar, Evertine J Abbink, Rob van Maanen, Oksana Pogoryelova, Claudia Stendel, Almut Bischoff, Ivan Karin, Mahtab Munshi, Anne Kümmel, Lydia Burgert, Christianne Verhaak, Herma Renkema
Brain. 2025 Mar; 148(3): 896–907. Published online 2024 Nov 6. doi: 10.1093/brain/awae277
PMCID:
PMC11884763
ArticlePDF–721K
9.
A comprehensive head-to-head comparison of key plasma phosphorylated tau 217 biomarker tests
Noëlle Warmenhoven, Gemma Salvadó, Shorena Janelidze, Niklas Mattsson-Carlgren, Divya Bali, Anna Orduña Dolado, Hartmuth Kolb, Gallen Triana-Baltzer, Nicolas R Barthélemy, Suzanne E Schindler, Andrew J Aschenbrenner, Cyrus A Raji, Tammie L S Benzinger, John C Morris, Laura Ibanez, Jigyasha Timsina, Carlos Cruchaga, Randall J Bateman, Nicholas Ashton, Burak Arslan, Henrik Zetterberg, Kaj Blennow, Alexa Pichet Binette, Oskar Hansson
Brain. 2025 Feb; 148(2): 416–431. Published online 2024 Oct 28. doi: 10.1093/brain/awae346
PMCID:
PMC11788211
ArticlePDF–1.1M
10.
Correction to: Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations
Brain. 2025 Jan; 148(1): e3. Published online 2024 Oct 28. doi: 10.1093/brain/awae332
Corrects:
Brain. 2024 Dec; 147(12): 4121–4130.
PMCID:
PMC11706279
CorrectionPDF–120K
11.
Neurodegenerative fluid biomarkers are enriched in human cervical lymph nodes
Adam Al-Diwani, Nicholas M Provine, Andrew Murchison, Rhiannon Laban, Owen J Swann, Ivan Koychev, Fintan Sheerin, Sandro Da Mesquita, Amanda Heslegrave, Henrik Zetterberg, Paul Klenerman, Sarosh R Irani
Brain. 2025 Feb; 148(2): 394–400. Published online 2024 Oct 21. doi: 10.1093/brain/awae329
PMCID:
PMC11788199
ArticlePDF–537K
12.
Lesion and lesion network localization of dysnomia after epilepsy surgery
Asmaa Mhanna, Joel Bruss, Joseph C Griffis, Alyssa W Sullivan, Hiroto Kawasaki, Jeffrey R Binder, Sara B Pillay, Matthew A Howard, III, Daniel Tranel, Aaron D Boes
Brain. 2025 Mar; 148(3): 776–787. Published online 2024 Oct 18. doi: 10.1093/brain/awae322
PMCID:
PMC11884675
ArticlePDF–650K
13.
Data-driven neuroanatomical subtypes of primary progressive aphasia
Beatrice Taylor, Martina Bocchetta, Cameron Shand, Emily G Todd, Anthipa Chokesuwattanaskul, Sebastian J Crutch, Jason D Warren, Jonathan D Rohrer, Chris J D Hardy, Neil P Oxtoby
Brain. 2025 Mar; 148(3): 955–968. Published online 2024 Oct 7. doi: 10.1093/brain/awae314
PMCID:
PMC11884653
ArticlePDF–1.1M
14.
Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations
Catarina Rua, Betty Raman, Christopher T Rodgers, Virginia F J Newcombe, Anne Manktelow, Doris A Chatfield, Stephen J Sawcer, Joanne G Outtrim, Victoria C Lupson, Emmanuel A Stamatakis, Guy B Williams, William T Clarke, Lin Qiu, Martyn Ezra, Rory McDonald, Stuart Clare, Mark Cassar, Stefan Neubauer, Karen D Ersche, Edward T Bullmore, David K Menon, Kyle Pattinson, James B Rowe
Brain. 2024 Dec; 147(12): 4121–4130. Published online 2024 Oct 7. doi: 10.1093/brain/awae215
Correction in:
Brain. 2025 Jan; 148(1): e3.
PMCID:
PMC7616766
ArticlePDF–561K
15.
High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury
Lucia M Li, Eleftheria Kodosaki, Amanda Heslegrave, Henrik Zetterberg, Neil Graham, Karl Zimmerman, Eyal Soreq, Thomas Parker, Elena Garbero, Federico Moro, Sandra Magnoni, Guido Bertolini, David J Loane, David J Sharp
Brain. 2025 Mar; 148(3): 1015–1030. Published online 2024 Sep 26. doi: 10.1093/brain/awae305
PMCID:
PMC11884744
ArticlePDF–1.0M
16.
BCAS1-positive oligodendrocytes enable efficient cortical remyelination in multiple sclerosis
Caroline Gertrud Bergner, Franziska van der Meer, Jonas Franz, Aigli Vakrakou, Thea Würfel, Stefan Nessler, Lisa Schäfer, Cora Nau-Gietz, Anne Winkler, Nielsen Lagumersindez-Denis, Claudia Wrzos, Ioanna Alkmini Damkou, Christina Sergiou, Verena Schultz, Carolin Knauer, Imke Metz, Erik Bahn, Enrique Garea Rodriguez, Doron Merkler, Mikael Simons, Christine Stadelmann
Brain. 2025 Mar; 148(3): 908–920. Published online 2024 Sep 25. doi: 10.1093/brain/awae293
PMCID:
PMC11884765
ArticlePDF–1.9M
17.
Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis
Kensuke Okada, Daisuke Ito, Satoru Morimoto, Chris Kato, Yuki Oguma, Hitoshi Warita, Naoki Suzuki, Masashi Aoki, Junko Kuramoto, Reona Kobayashi, Munehisa Shinozaki, Masahito Ikawa, Jin Nakahara, Shinichi Takahashi, Yoshinori Nishimoto, Shinsuke Shibata, Hideyuki Okano
Brain. 2024 Nov; 147(11): 3933–3948. Published online 2024 Sep 23. doi: 10.1093/brain/awae224
PMCID:
PMC11684083
ArticlePDF–1.4M
18.
Anatomical and behavioural correlates of auditory perception in developmental dyslexia
Ting Qi, Maria Luisa Mandelli, Christa L Watson Pereira, Emma Wellman, Rian Bogley, Abigail E Licata, Zachary A Miller, Boon Lead Tee, Jessica de Leon, Edward F Chang, Yulia Oganian, Maria Luisa Gorno-Tempini
Brain. 2025 Mar; 148(3): 833–844. Published online 2024 Sep 20. doi: 10.1093/brain/awae298
PMCID:
PMC11884757
ArticlePDF–591K
19.
Decision cost hypersensitivity underlies Huntington’s disease apathy
Lee-Anne Morris, Kyla-Louise Horne, Sanjay Manohar, Laura Paermentier, Christina M Buchanan, Michael R MacAskill, Daniel J Myall, Matthew Apps, Richard Roxburgh, Tim J Anderson, Masud Husain, Campbell J Le Heron
Brain. 2025 Mar; 148(3): 861–874. Published online 2024 Sep 12. doi: 10.1093/brain/awae296
PMCID:
PMC11884755
ArticlePDF–879K
20.
Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis
Rachel J Sharkey, Filomeno Cortese, Bradley G Goodyear, Lawrence W Korngut, Sarah M Jacob, Keith A Sharkey, Sanjay Kalra, Minh Dang Nguyen, Richard Frayne, Gerald Pfeffer
Brain. 2024 Dec; 147(12): 4026–4032. Published online 2024 Sep 6. doi: 10.1093/brain/awae288
PMCID:
PMC11629681
ArticlePDF–434K

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