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Psychomotor retardation

MedGen UID:
1788358
•Concept ID:
C5441816
•
Finding
Synonyms: Impairment, Psychomotor; Impairments, Psychomotor; Psychomotor Impairment; Psychomotor Impairments
SNOMED CT: Psychomotor retardation (1144814003)

Definition

Abnormally slow physical movement. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • Psychomotor retardation

Professional guidelines

PubMed

Treatment of maple syrup urine disease: Benefits, risks, and challenges of liver transplantation.
Deon M, Guerreiro G, Girardi J, Ribas G, Vargas CR
Int J Dev Neurosci 2023 Oct;83(6):489-504. Epub 2023 Jun 20 doi: 10.1002/jdn.10283. PMID: 37340513
Management of Toxoplasma gondii infection during pregnancy.
Montoya JG, Remington JS
Clin Infect Dis 2008 Aug 15;47(4):554-66. doi: 10.1086/590149. PMID: 18624630
Lorazepam for treatment of catatonic symptoms and severe psychomotor retardation.
Wetzel H, Benkert O
Am J Psychiatry 1988 Sep;145(9):1175-6. doi: 10.1176/ajp.145.9.1175b. PMID: 3414861

Recent clinical studies

Etiology

The why, when, where, how, and so what of so-called rapidly acting antidepressants.
Schatzberg AF, Mathew SJ
Neuropsychopharmacology 2024 Jan;49(1):189-196. Epub 2023 Jul 17 doi: 10.1038/s41386-023-01647-8. PMID: 37460770Free PMC Article
Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article
SSRI antidepressants: altered psychomotor development following exposure in utero?
Prescrire Int 2013 Feb;22(135):43-4. PMID: 23444502
Allergic rhinitis.
Greiner AN, Hellings PW, Rotiroti G, Scadding GK
Lancet 2011 Dec 17;378(9809):2112-22. Epub 2011 Jul 23 doi: 10.1016/S0140-6736(11)60130-X. PMID: 21783242
Cerebral folate deficiency.
Hyland K, Shoffner J, Heales SJ
J Inherit Metab Dis 2010 Oct;33(5):563-70. Epub 2010 Jul 29 doi: 10.1007/s10545-010-9159-6. PMID: 20668945

Diagnosis

Rethinking Catatonia: New Insights from the Autism Spectrum.
Dell'Osso L, Toschi D, Amatori G, Gesi C
CNS Neurol Disord Drug Targets 2023;22(4):462-465. doi: 10.2174/1871527321666220406105844. PMID: 35388766
Catatonia Update.
Brar K, Kaushik SS, Lippmann S
Prim Care Companion CNS Disord 2017 Oct 26;19(5) doi: 10.4088/PCC.16br02023. PMID: 29099544
Anhedonia revisited: is there a role for dopamine-targeting drugs for depression?
Argyropoulos SV, Nutt DJ
J Psychopharmacol 2013 Oct;27(10):869-77. Epub 2013 Jul 31 doi: 10.1177/0269881113494104. PMID: 23904408
Cerebral malformations without antenatal diagnosis.
Girard NJ
Pediatr Radiol 2010 Jun;40(6):834-43. Epub 2010 Apr 30 doi: 10.1007/s00247-010-1595-9. PMID: 20432001
Familial homocystinuria.
Bilwani F, Syed NA, Usman M, Khurshid M
J Coll Physicians Surg Pak 2005 Feb;15(2):106-7. PMID: 15730839

Therapy

Anhedonia revisited: is there a role for dopamine-targeting drugs for depression?
Argyropoulos SV, Nutt DJ
J Psychopharmacol 2013 Oct;27(10):869-77. Epub 2013 Jul 31 doi: 10.1177/0269881113494104. PMID: 23904408
Management of Toxoplasma gondii infection during pregnancy.
Montoya JG, Remington JS
Clin Infect Dis 2008 Aug 15;47(4):554-66. doi: 10.1086/590149. PMID: 18624630
Treatment with amino acids in serine deficiency disorders.
de Koning TJ
J Inherit Metab Dis 2006 Apr-Jun;29(2-3):347-51. doi: 10.1007/s10545-006-0269-0. PMID: 16763900
Tryptophan antidepressant 'physiological sedative': fact or fancy?
Cooper AJ
Psychopharmacology (Berl) 1979 Mar 14;61(1):97-102. doi: 10.1007/BF00426818. PMID: 108727
Apomorphine and psychopathology.
Lal S, De la Vega CE
J Neurol Neurosurg Psychiatry 1975 Jul;38(7):722-6. doi: 10.1136/jnnp.38.7.722. PMID: 1099172Free PMC Article

Prognosis

Treatment of maple syrup urine disease: Benefits, risks, and challenges of liver transplantation.
Deon M, Guerreiro G, Girardi J, Ribas G, Vargas CR
Int J Dev Neurosci 2023 Oct;83(6):489-504. Epub 2023 Jun 20 doi: 10.1002/jdn.10283. PMID: 37340513
Stress, sex hormones, inflammation, and major depressive disorder: Extending Social Signal Transduction Theory of Depression to account for sex differences in mood disorders.
Slavich GM, Sacher J
Psychopharmacology (Berl) 2019 Oct;236(10):3063-3079. Epub 2019 Jul 29 doi: 10.1007/s00213-019-05326-9. PMID: 31359117Free PMC Article
From stress to inflammation and major depressive disorder: a social signal transduction theory of depression.
Slavich GM, Irwin MR
Psychol Bull 2014 May;140(3):774-815. Epub 2014 Jan 13 doi: 10.1037/a0035302. PMID: 24417575Free PMC Article
Lowe syndrome.
Loi M
Orphanet J Rare Dis 2006 May 18;1:16. doi: 10.1186/1750-1172-1-16. PMID: 16722554Free PMC Article
Posttraumatic hydrocephalus.
Beyerl B, Black PM
Neurosurgery 1984 Aug;15(2):257-61. doi: 10.1227/00006123-198408000-00020. PMID: 6384812

Clinical prediction guides

Adenylosuccinate lyase deficiency.
Jurecka A, Zikanova M, Kmoch S, Tylki-Szymańska A
J Inherit Metab Dis 2015 Mar;38(2):231-42. Epub 2014 Aug 12 doi: 10.1007/s10545-014-9755-y. PMID: 25112391Free PMC Article
MAN1B1 deficiency: an unexpected CDG-II.
Rymen D, Peanne R, Millón MB, Race V, Sturiale L, Garozzo D, Mills P, Clayton P, Asteggiano CG, Quelhas D, Cansu A, Martins E, Nassogne MC, Gonçalves-Rocha M, Topaloglu H, Jaeken J, Foulquier F, Matthijs G
PLoS Genet 2013;9(12):e1003989. Epub 2013 Dec 12 doi: 10.1371/journal.pgen.1003989. PMID: 24348268Free PMC Article
Terminal 14q32.33 deletion: genotype-phenotype correlation.
Maurin ML, Brisset S, Le Lorc'h M, Poncet V, Trioche P, Aboura A, Labrune P, Tachdjian G
Am J Med Genet A 2006 Nov 1;140(21):2324-9. doi: 10.1002/ajmg.a.31438. PMID: 17022077
Posttraumatic hydrocephalus.
Beyerl B, Black PM
Neurosurgery 1984 Aug;15(2):257-61. doi: 10.1227/00006123-198408000-00020. PMID: 6384812
Apomorphine and psychopathology.
Lal S, De la Vega CE
J Neurol Neurosurg Psychiatry 1975 Jul;38(7):722-6. doi: 10.1136/jnnp.38.7.722. PMID: 1099172Free PMC Article

Recent systematic reviews

Motor alterations in depression and anxiety disorders: A systematic review and meta-analysis.
Elkjær E, Mikkelsen MB, Michalak J, Mennin DS, O'Toole MS
J Affect Disord 2022 Nov 15;317:373-387. Epub 2022 Aug 28 doi: 10.1016/j.jad.2022.08.060. PMID: 36037990
Actigraphically measured psychomotor slowing in depression: systematic review and meta-analysis.
Wüthrich F, Nabb CB, Mittal VA, Shankman SA, Walther S
Psychol Med 2022 May;52(7):1208-1221. Epub 2022 May 13 doi: 10.1017/S0033291722000903. PMID: 35550677Free PMC Article
The association between hypoparathyroidism and cognitive impairment: a systematic review.
Sardella A, Bellone F, Morabito N, Minisola S, Basile G, Corica F, Catalano A
J Endocrinol Invest 2021 May;44(5):905-919. Epub 2020 Sep 14 doi: 10.1007/s40618-020-01423-1. PMID: 32926396
Melancholia: An Attempt at Definition Based on a Review of Empirical Data.
Martino DJ, Szmulewicz AG, Valerio MP, Parker G
J Nerv Ment Dis 2019 Sep;207(9):792-798. doi: 10.1097/NMD.0000000000001090. PMID: 31464990
Psychomotor retardation in depression: a systematic review of diagnostic, pathophysiologic, and therapeutic implications.
Bennabi D, Vandel P, Papaxanthis C, Pozzo T, Haffen E
Biomed Res Int 2013;2013:158746. Epub 2013 Oct 30 doi: 10.1155/2013/158746. PMID: 24286073Free PMC Article

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