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NOR polyagglutination syndrome

MedGen UID:: 762400
•Concept ID:: C3549486
•: Disease or Syndrome

Synonym:	NOR POLYAGGLUTINATION SYNDROME

OMIM®:	111400; 607922

Recent clinical studies

Etiology

A case of Tn polyagglutination discovered by an ABO blood group discrepancy.

Achram R, Denomme GA, Stef MA, Nguyen TTA, Delvadia B, Thompson L, Josephson CD, Roback JD, Sullivan HC
Transfusion 2022 Jul;62(7):1452-1456. Epub 2022 Jun 24 doi: 10.1111/trf.16966. PMID: 35748659

Tn Red cell polyagglutination in a healthy blood donor: A case report.

Ray GK, Mukherjee S, Routray SS, Prakash S
Transfus Apher Sci 2021 Feb;60(1):103013. Epub 2020 Nov 24 doi: 10.1016/j.transci.2020.103013. PMID: 33272849

The classification, recognition and significance of polyagglutination in transfusion medicine.

Horn KD
Blood Rev 1999 Mar;13(1):36-44. doi: 10.1016/s0268-960x(99)90021-8. PMID: 10225607

The origin of human B and T cells from multipotent stem cells: a study of the Tn syndrome.

Brouet JC, Vainchenker W, Blanchard D, Testa U, Cartron JP
Eur J Immunol 1983 Apr;13(4):350-2. doi: 10.1002/eji.1830130416. PMID: 6602054

Galactosyltransferase and membrane glycoprotein abnormality in human platelets from Tn-syndrome donors.

Cartron JP, Nurden AT
Nature 1979 Dec 6;282(5739):621-3. doi: 10.1038/282621a0. PMID: 121764

See all (11)

Diagnosis

Minor Cross-Matching in the Diagnosis of Pneumococcal Hemolytic Uremic Syndrome in an 18-Month-Old Boy.

Routray SS, Tripathy S, Das P, Ray GK
Lab Med 2023 Mar 7;54(2):215-219. doi: 10.1093/labmed/lmac092. PMID: 36124770

A severe case of atypical hemolytic uremic syndrome associated with pneumococcal infection and T activation treated successfully with plasma exchange.

Hopkins CK, Yuan S, Lu Q, Ziman A, Goldfinger D
Transfusion 2008 Nov;48(11):2448-52. Epub 2008 Jul 30 doi: 10.1111/j.1537-2995.2008.01871.x. PMID: 18673349

Monoclonal antibodies for the detection of desialylation of erythrocyte membranes during haemolytic disease and haemolytic uraemic syndrome caused by the in vivo action of microbial neuraminidase.

Seitz RC, Poschmann A, Hellwege HH
Glycoconj J 1997 Sep;14(6):699-706. doi: 10.1023/a:1018565316310. PMID: 9337082

Isolation of Yersinia group in human infections, animals and environment factors.

Constantiniu S
Arch Roum Pathol Exp Microbiol 1990 Apr-Jun;49(2):131-7. PMID: 2101210

Exposure of cryptantigens on red blood cell membranes in patients with acquired immune deficiency syndrome or AIDS-related complex.

Adams M, Toy PT, Reid ME
J Acquir Immune Defic Syndr (1988) 1989;2(3):224-8. PMID: 2656988

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Therapy

A severe case of atypical hemolytic uremic syndrome associated with pneumococcal infection and T activation treated successfully with plasma exchange.

Hopkins CK, Yuan S, Lu Q, Ziman A, Goldfinger D
Transfusion 2008 Nov;48(11):2448-52. Epub 2008 Jul 30 doi: 10.1111/j.1537-2995.2008.01871.x. PMID: 18673349

See all (1)

Prognosis

Haemolytic uraemic syndrome and the Thomsen Friedenreich antigen.

McGraw ME, Lendon M, Stevens RF, Postlethwaite RJ, Taylor CM
Pediatr Nephrol 1989 Apr;3(2):135-9. doi: 10.1007/BF00852894. PMID: 2701864

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Clinical prediction guides

Clonal expression of the Tn antigen in erythroid and granulocyte colonies and its application to determination of the clonality of the human megakaryocyte colony assay.

Vainchenker W, Testa U, Deschamps JF, Henri A, Titeux M, Breton-Gorius J, Rochant H, Lee D, Cartron JP
J Clin Invest 1982 May;69(5):1081-91. doi: 10.1172/jci110543. PMID: 6175663 Free PMC Article

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NOR polyagglutination syndrome

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

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