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Gallbladder disease 4(GBD4)

MedGen UID:
370601
Concept ID:
C1969115
Disease or Syndrome
Synonym: GBD4
 
Gene (location): ABCG8 (2p21)
 
OMIM®: 611465

Clinical features

From HPO
Cholelithiasis
MedGen UID:
3039
Concept ID:
C0008350
Disease or Syndrome
Hard, pebble-like deposits that form within the gallbladder.

Professional guidelines

PubMed

Lategan C, Wang X, Chisholm C, Hsu Z, Lang E
CJEM 2025 Feb;27(2):134-143. Epub 2025 Jan 3 doi: 10.1007/s43678-024-00832-y. PMID: 39752086

Recent clinical studies

Etiology

Colling KP, Besshoff KE, Forrester JD, Kendrick D, Mercier P, Huston JM
Surg Infect (Larchmt) 2022 May;23(4):339-350. Epub 2022 Mar 31 doi: 10.1089/sur.2021.207. PMID: 35363086
Wilkins T, Agabin E, Varghese J, Talukder A
Prim Care 2017 Dec;44(4):575-597. Epub 2017 Oct 5 doi: 10.1016/j.pop.2017.07.002. PMID: 29132521
Elshaer M, Gravante G, Thomas K, Sorge R, Al-Hamali S, Ebdewi H
JAMA Surg 2015 Feb;150(2):159-68. doi: 10.1001/jamasurg.2014.1219. PMID: 25548894
Ansari S
Indian J Gastroenterol 2014 Jul;33(4):399. doi: 10.1007/s12664-013-0362-x. PMID: 23982704
Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH
BMC Public Health 2009 Mar 25;9:88. doi: 10.1186/1471-2458-9-88. PMID: 19320986Free PMC Article

Diagnosis

Wilkins T, Agabin E, Varghese J, Talukder A
Prim Care 2017 Dec;44(4):575-597. Epub 2017 Oct 5 doi: 10.1016/j.pop.2017.07.002. PMID: 29132521
Rothstein DH, Harmon CM
Semin Pediatr Surg 2016 Aug;25(4):225-31. Epub 2016 May 11 doi: 10.1053/j.sempedsurg.2016.05.005. PMID: 27521713
Baron TH, Grimm IS, Swanstrom LL
N Engl J Med 2015 Jul 23;373(4):357-65. doi: 10.1056/NEJMra1411372. PMID: 26200981
Machi J, Oishi AJ, Furumoto NL, Oishi RH
Surg Clin North Am 2004 Aug;84(4):1085-111, vi-i. doi: 10.1016/j.suc.2004.04.001. PMID: 15261754
Kerstein MD, Sheahan DG, Gudjonsson B, Lewis J
Am J Gastroenterol 1976 Oct;66(4):349-52. PMID: 998596

Therapy

He L, Wang J, Ping F, Yang N, Huang J, Li W, Xu L, Zhang H, Li Y
BMJ 2022 Jun 28;377:e068882. doi: 10.1136/bmj-2021-068882. PMID: 35764326Free PMC Article
Nassar A, Elshahat I, Forsyth K, Shaikh S, Ghazanfar M
HPB (Oxford) 2022 Oct;24(10):1622-1633. Epub 2022 May 6 doi: 10.1016/j.hpb.2022.04.010. PMID: 35597717
Colling KP, Besshoff KE, Forrester JD, Kendrick D, Mercier P, Huston JM
Surg Infect (Larchmt) 2022 May;23(4):339-350. Epub 2022 Mar 31 doi: 10.1089/sur.2021.207. PMID: 35363086
Gallaher JR, Charles A
JAMA 2022 Mar 8;327(10):965-975. doi: 10.1001/jama.2022.2350. PMID: 35258527
Bellows CF, Berger DH, Crass RA
Am Fam Physician 2005 Aug 15;72(4):637-42. PMID: 16127953

Prognosis

Yu Z, Bai X, Zhou R, Ruan G, Guo M, Han W, Jiang S, Yang H
Int J Cancer 2024 Feb 15;154(4):615-625. Epub 2023 Sep 26 doi: 10.1002/ijc.34740. PMID: 37750191
Poddighe D, Sazonov V
World J Gastroenterol 2018 Nov 21;24(43):4870-4879. doi: 10.3748/wjg.v24.i43.4870. PMID: 30487697Free PMC Article
Willekens I, Verdries D, Ceulemans G, Vandenbroucke F, Delvaux G, de Mey J
JBR-BTR 2010 Jan-Feb;93(1):4-6. doi: 10.5334/jbr-btr.24. PMID: 20397425
Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH
BMC Public Health 2009 Mar 25;9:88. doi: 10.1186/1471-2458-9-88. PMID: 19320986Free PMC Article
Paraskevopoulos JA, Dennison AR, Johnson AG
HPB Surg 1991;4(4):277-89. doi: 10.1155/1991/92731. PMID: 1810370Free PMC Article

Clinical prediction guides

Unalp-Arida A, Ruhl CE
Hepatology 2023 Jun 1;77(6):1882-1895. Epub 2023 Jan 13 doi: 10.1097/HEP.0000000000000264. PMID: 36631004
Gallaher JR, Charles A
JAMA 2022 Mar 8;327(10):965-975. doi: 10.1001/jama.2022.2350. PMID: 35258527
Zhang Y, Zuo C, Liu L, Hu Y, Yang B, Qiu S, Li Y, Cao D, Ju Z, Ge J, Wang Q, Wang T, Bai L, Yang Y, Li G, Shao Z, Gao Y, Li Y, Bian R, Miao H, Li L, Li X, Jiang C, Yan S, Wang Z, Wang Z, Cui X, Huang W, Xiang D, Wang C, Li Q, Wu X, Gong W, Liu Y, Shao R, Liu F, Li M, Chen L, Liu Y
J Hepatol 2021 Nov;75(5):1128-1141. Epub 2021 Jun 23 doi: 10.1016/j.jhep.2021.06.023. PMID: 34171432
Madni TD, Leshikar DE, Minshall CT, Nakonezny PA, Cornelius CC, Imran JB, Clark AT, Williams BH, Eastman AL, Minei JP, Phelan HA, Cripps MW
Am J Surg 2018 Apr;215(4):625-630. Epub 2017 Jun 6 doi: 10.1016/j.amjsurg.2017.05.017. PMID: 28619262
O'Connor OJ, Maher MM
AJR Am J Roentgenol 2011 Apr;196(4):W367-74. doi: 10.2214/AJR.10.4340. PMID: 21427298

Recent systematic reviews

Meier J, Guzzetta AA, Huerta S
Am Surg 2020 Jun;86(6):675-684. doi: 10.1177/0003134820923296. PMID: 32683979
Marjoribanks J, Farquhar C, Roberts H, Lethaby A, Lee J
Cochrane Database Syst Rev 2017 Jan 17;1(1):CD004143. doi: 10.1002/14651858.CD004143.pub5. PMID: 28093732Free PMC Article
Coccolini F, Catena F, Pisano M, Gheza F, Fagiuoli S, Di Saverio S, Leandro G, Montori G, Ceresoli M, Corbella D, Sartelli M, Sugrue M, Ansaloni L
Int J Surg 2015 Jun;18:196-204. Epub 2015 May 6 doi: 10.1016/j.ijsu.2015.04.083. PMID: 25958296
Elshaer M, Gravante G, Thomas K, Sorge R, Al-Hamali S, Ebdewi H
JAMA Surg 2015 Feb;150(2):159-68. doi: 10.1001/jamasurg.2014.1219. PMID: 25548894
Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH
BMC Public Health 2009 Mar 25;9:88. doi: 10.1186/1471-2458-9-88. PMID: 19320986Free PMC Article

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