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Insulin resistance, susceptibility to

MedGen UID:
343716
•Concept ID:
C1852091
•
Finding
Synonym: INSULIN RESISTANCE, SUSCEPTIBILITY TO
 
OMIM®: 125853; 142410; 147545; 173335; 176885; 600917

Professional guidelines

PubMed

Adiposity in Children Born Small for Gestational Age Is Associated With β-Cell Function, Genetic Variants for Insulin Resistance, and Response to Growth Hormone Treatment.
Thankamony A, Jensen RB, O'Connell SM, Day F, Kirk J, Donaldson M, Ivarsson SA, Söder O, Roche E, Hoey H, Ong KK, Dunger DB, Juul A
J Clin Endocrinol Metab 2016 Jan;101(1):131-42. Epub 2015 Nov 20 doi: 10.1210/jc.2015-3019. PMID: 26588449Free PMC Article

Recent clinical studies

Etiology

Metabolic Syndrome: Updates on Pathophysiology and Management in 2021.
Fahed G, Aoun L, Bou Zerdan M, Allam S, Bou Zerdan M, Bouferraa Y, Assi HI
Int J Mol Sci 2022 Jan 12;23(2) doi: 10.3390/ijms23020786. PMID: 35054972Free PMC Article
Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
Malone JI, Hansen BC
Pediatr Diabetes 2019 Feb;20(1):5-9. Epub 2018 Nov 5 doi: 10.1111/pedi.12787. PMID: 30311716
Genetics of Insulin Resistance and the Metabolic Syndrome.
Brown AE, Walker M
Curr Cardiol Rep 2016 Aug;18(8):75. doi: 10.1007/s11886-016-0755-4. PMID: 27312935Free PMC Article
Metabolic syndrome.
Samson SL, Garber AJ
Endocrinol Metab Clin North Am 2014 Mar;43(1):1-23. doi: 10.1016/j.ecl.2013.09.009. PMID: 24582089
Risk factors for type 2 diabetes mellitus.
Fletcher B, Gulanick M, Lamendola C
J Cardiovasc Nurs 2002 Jan;16(2):17-23. doi: 10.1097/00005082-200201000-00003. PMID: 11800065

Diagnosis

Gut microbiota: A new target for T2DM prevention and treatment.
Liu L, Zhang J, Cheng Y, Zhu M, Xiao Z, Ruan G, Wei Y
Front Endocrinol (Lausanne) 2022;13:958218. Epub 2022 Aug 11 doi: 10.3389/fendo.2022.958218. PMID: 36034447Free PMC Article
Metabolic Syndrome: Updates on Pathophysiology and Management in 2021.
Fahed G, Aoun L, Bou Zerdan M, Allam S, Bou Zerdan M, Bouferraa Y, Assi HI
Int J Mol Sci 2022 Jan 12;23(2) doi: 10.3390/ijms23020786. PMID: 35054972Free PMC Article
Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease.
Yanai H, Adachi H, Hakoshima M, Katsuyama H
Int J Mol Sci 2021 Aug 26;22(17) doi: 10.3390/ijms22179221. PMID: 34502127Free PMC Article
Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
Malone JI, Hansen BC
Pediatr Diabetes 2019 Feb;20(1):5-9. Epub 2018 Nov 5 doi: 10.1111/pedi.12787. PMID: 30311716
Polycystic Ovary Syndrome.
Azziz R
Obstet Gynecol 2018 Aug;132(2):321-336. doi: 10.1097/AOG.0000000000002698. PMID: 29995717

Therapy

Microbial Medicine: Prebiotic and Probiotic Functional Foods to Target Obesity and Metabolic Syndrome.
Green M, Arora K, Prakash S
Int J Mol Sci 2020 Apr 21;21(8) doi: 10.3390/ijms21082890. PMID: 32326175Free PMC Article
Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
Malone JI, Hansen BC
Pediatr Diabetes 2019 Feb;20(1):5-9. Epub 2018 Nov 5 doi: 10.1111/pedi.12787. PMID: 30311716
l-Citrulline Supplementation: Impact on Cardiometabolic Health.
Allerton TD, Proctor DN, Stephens JM, Dugas TR, Spielmann G, Irving BA
Nutrients 2018 Jul 19;10(7) doi: 10.3390/nu10070921. PMID: 30029482Free PMC Article
Insulin and the polycystic ovary syndrome.
Macut D, Bjekić-Macut J, Rahelić D, Doknić M
Diabetes Res Clin Pract 2017 Aug;130:163-170. Epub 2017 Jun 12 doi: 10.1016/j.diabres.2017.06.011. PMID: 28646699
Diabetes and Stroke: Epidemiology, Pathophysiology, Pharmaceuticals and Outcomes.
Chen R, Ovbiagele B, Feng W
Am J Med Sci 2016 Apr;351(4):380-6. doi: 10.1016/j.amjms.2016.01.011. PMID: 27079344Free PMC Article

Prognosis

The cause-effect relation of tuberculosis on incidence of diabetes mellitus.
Bisht MK, Dahiya P, Ghosh S, Mukhopadhyay S
Front Cell Infect Microbiol 2023;13:1134036. Epub 2023 Jun 26 doi: 10.3389/fcimb.2023.1134036. PMID: 37434784Free PMC Article
The multiple roles of life stress in metabolic disorders.
Kivimäki M, Bartolomucci A, Kawachi I
Nat Rev Endocrinol 2023 Jan;19(1):10-27. Epub 2022 Oct 12 doi: 10.1038/s41574-022-00746-8. PMID: 36224493Free PMC Article
Nutritional guidelines for the management of insulin resistance.
Muscogiuri G, Barrea L, Caprio M, Ceriani F, Chavez AO, El Ghoch M, Frias-Toral E, Mehta RJ, Mendez V, Paschou SA, Pazderska A, Savastano S, Colao A
Crit Rev Food Sci Nutr 2022;62(25):6947-6960. Epub 2021 Apr 2 doi: 10.1080/10408398.2021.1908223. PMID: 33797999
Epidemiology of Hepatocellular Carcinoma.
McGlynn KA, Petrick JL, El-Serag HB
Hepatology 2021 Jan;73 Suppl 1(Suppl 1):4-13. Epub 2020 Nov 24 doi: 10.1002/hep.31288. PMID: 32319693Free PMC Article
The Genetic Epidemiology of Type 2 Diabetes: Opportunities for Health Translation.
Meigs JB
Curr Diab Rep 2019 Jul 22;19(8):62. doi: 10.1007/s11892-019-1173-y. PMID: 31332628Free PMC Article

Clinical prediction guides

Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease.
Yanai H, Adachi H, Hakoshima M, Katsuyama H
Int J Mol Sci 2021 Aug 26;22(17) doi: 10.3390/ijms22179221. PMID: 34502127Free PMC Article
Precision Nutrition for Alzheimer's Prevention in ApoE4 Carriers.
Norwitz NG, Saif N, Ariza IE, Isaacson RS
Nutrients 2021 Apr 19;13(4) doi: 10.3390/nu13041362. PMID: 33921683Free PMC Article
The Genetic Epidemiology of Type 2 Diabetes: Opportunities for Health Translation.
Meigs JB
Curr Diab Rep 2019 Jul 22;19(8):62. doi: 10.1007/s11892-019-1173-y. PMID: 31332628Free PMC Article
Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
Malone JI, Hansen BC
Pediatr Diabetes 2019 Feb;20(1):5-9. Epub 2018 Nov 5 doi: 10.1111/pedi.12787. PMID: 30311716
Genetics of Insulin Resistance and the Metabolic Syndrome.
Brown AE, Walker M
Curr Cardiol Rep 2016 Aug;18(8):75. doi: 10.1007/s11886-016-0755-4. PMID: 27312935Free PMC Article

Recent systematic reviews

Prevalence of sarcopenic obesity in patients with diabetes and adverse outcomes: A systematic review and meta-analysis.
Zhou YY, Wang JF, Yao Q, Jian QF, Luo ZP
Clin Nutr ESPEN 2023 Dec;58:128-135. Epub 2023 Sep 29 doi: 10.1016/j.clnesp.2023.09.920. PMID: 38056996
Hidradenitis suppurativa and metabolic syndrome - systematic review and adjusted meta-analysis.
Phan K, Charlton O, Smith SD
Int J Dermatol 2019 Oct;58(10):1112-1117. Epub 2019 May 31 doi: 10.1111/ijd.14500. PMID: 31148159
A Systematic Review on Sasang Constitutional Type-Associated Susceptibility to Disorders in Korea.
Lee HY, Lee WJ, Kim HW, Jang ES, Ahn YC, Ku BC, Kang W, Lee SW, Son CG
J Altern Complement Med 2016 Dec;22(12):950-956. Epub 2016 Oct 18 doi: 10.1089/acm.2016.0177. PMID: 27754711
The impact of high-intensity interval training versus moderate-intensity continuous training on vascular function: a systematic review and meta-analysis.
Ramos JS, Dalleck LC, Tjonna AE, Beetham KS, Coombes JS
Sports Med 2015 May;45(5):679-92. doi: 10.1007/s40279-015-0321-z. PMID: 25771785
Genetic variants and the metabolic syndrome: a systematic review.
Povel CM, Boer JM, Reiling E, Feskens EJ
Obes Rev 2011 Nov;12(11):952-67. Epub 2011 Jul 12 doi: 10.1111/j.1467-789X.2011.00907.x. PMID: 21749608

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