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Colorectal carcinoma(CRC)

MedGen UID:
3170
•Concept ID:
C0009402
•
Neoplastic Process
Synonyms: Cancer, Colorectal; Cancers, Colorectal; Carcinoma, Colorectal; Carcinomas, Colorectal; Colorectal Cancer; Colorectal Cancers; Colorectal Carcinoma; Colorectal Carcinomas
 
Monarch Initiative: MONDO:0024331
OMIM®: 114500; 172411; 191170; 516000; 516004; 516020; 516030; 516040

Definition

A malignant epithelial neoplasm that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa. The vast majority are adenocarcinomas. [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Colorectal carcinoma: overview of clinical research and management 2011.
Krishnamurthi SS, Meropol NJ
Semin Oncol 2011 Aug;38(4):481-2. doi: 10.1053/j.seminoncol.2011.05.001. PMID: 21810506
Guidelines for the management of iron deficiency anaemia.
Goddard AF, James MW, McIntyre AS, Scott BB; British Society of Gastroenterology
Gut 2011 Oct;60(10):1309-16. Epub 2011 May 11 doi: 10.1136/gut.2010.228874. PMID: 21561874
Experimental chemotherapeutic agents for the treatment of colorectal carcinoma.
O'Reilly S, Rowinsky EK
Hematol Oncol Clin North Am 1997 Aug;11(4):721-58. doi: 10.1016/s0889-8588(05)70458-5. PMID: 9257153

Curated

DailyMed Drug Label, Capecitabine, 2021

Recent clinical studies

Etiology

An App to Improve Colorectal Carcinoma Follow-Up.
Wyss L, Stierlin M
Stud Health Technol Inform 2019;259:109-112. PMID: 30923285
Food, microbiome and colorectal cancer.
Niederreiter L, Adolph TE, Tilg H
Dig Liver Dis 2018 Jul;50(7):647-652. Epub 2018 Apr 3 doi: 10.1016/j.dld.2018.03.030. PMID: 29705028
Management of colorectal carcinoma in children and young adults.
Goldberg J, Furman WL
J Pediatr Hematol Oncol 2012 May;34 Suppl 2:S76-9. doi: 10.1097/MPH.0b013e31824e38c1. PMID: 22525412
Colorectal carcinoma: etiology, diagnosis, and screening.
Bedine MS
Compr Ther 1999 Mar;25(3):163-8. doi: 10.1007/BF02889613. PMID: 10200906
The evolution of colorectal carcinoma.
Morson BC
Clin Radiol 1984 Nov;35(6):425-31. doi: 10.1016/s0009-9260(84)80033-1. PMID: 6499378

Diagnosis

Histology of Colorectal Carcinoma: Proven and Purported Prognostic Factors.
Johncilla M, Yantiss RK
Surg Pathol Clin 2020 Sep;13(3):503-520. Epub 2020 Jul 9 doi: 10.1016/j.path.2020.05.008. PMID: 32773197
An App to Improve Colorectal Carcinoma Follow-Up.
Wyss L, Stierlin M
Stud Health Technol Inform 2019;259:109-112. PMID: 30923285
Colorectal carcinoma: etiology, diagnosis, and screening.
Bedine MS
Compr Ther 1999 Mar;25(3):163-8. doi: 10.1007/BF02889613. PMID: 10200906
Imaging in colorectal carcinoma.
Taylor AJ, Youker JE
Semin Oncol 1991 Apr;18(2):99-110. PMID: 2014406
Colostomy.
Alterescu KB
Nurs Clin North Am 1987 Jun;22(2):281-9. PMID: 3646660

Therapy

Organ-specific cholesterol metabolic aberration fuels liver metastasis of colorectal cancer.
Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, Lu L, Jia HL, Dong QZ, Chen JH, Lu M, Qin LX
Theranostics 2021;11(13):6560-6572. Epub 2021 Apr 27 doi: 10.7150/thno.55609. PMID: 33995676Free PMC Article
Selective Internal Radiation Therapy in the Multidisciplinary Management of Liver Metastases From Colorectal Carcinoma.
Tchelebi L, Sharma NK
Semin Nucl Med 2019 May;49(3):182-188. Epub 2019 Feb 14 doi: 10.1053/j.semnuclmed.2019.01.002. PMID: 30954183
Targeted therapy in colorectal carcinoma: more than a theory.
Pickering L, Rudman S, Ross PJ, Leslie MD
Colorectal Dis 2008 Mar;10(3):209-18; discussion 218-221. doi: 10.1111/j.1463-1318.2008.01495.x. PMID: 18257846
Resection of liver metastases of colorectal carcinoma.
Nakamura S, Suzuki S, Baba S
World J Surg 1997 Sep;21(7):741-7. doi: 10.1007/s002689900300. PMID: 9276706
Role of leucovorin dosing and administration schedule.
Jolivet J
Eur J Cancer 1995 Jul-Aug;31A(7-8):1311-5. doi: 10.1016/0959-8049(95)00140-e. PMID: 7577042

Prognosis

Ablation for oligometastatic colorectal carcinoma in extrahepatic, extrapulmonary sites.
Thompson SM, Welch BT, Kurup AN
Int J Hyperthermia 2022;39(1):633-638. doi: 10.1080/02656736.2021.1952318. PMID: 35465801
Colorectal carcinoma in children and adolescents.
Mathey MD, Pennella CL, Zubizarreta P
Arch Argent Pediatr 2021 Oct;119(5):e487-e498. doi: 10.5546/aap.2021.eng.e487. PMID: 34569749
Intra-abdominal recurrence from colorectal carcinoma: Differences and similarities between local and peritoneal recurrence.
Dumont F, Joseph S, Lorimier G, De Franco V, Wernert R, Verriele V, Kerdraon O, Campion L, Capitain O, Guerin-Meyer V, Raimbourg J, Senellart H, Hiret S, Raoul JL, Thibaudeau E
Surg Oncol 2020 Mar;32:23-29. Epub 2019 Nov 4 doi: 10.1016/j.suronc.2019.10.018. PMID: 31707314
Management of colorectal carcinoma in children and young adults.
Goldberg J, Furman WL
J Pediatr Hematol Oncol 2012 May;34 Suppl 2:S76-9. doi: 10.1097/MPH.0b013e31824e38c1. PMID: 22525412
Routine imaging studies for the posttreatment surveillance of breast and colorectal carcinoma.
Kagan AR, Steckel RJ
J Clin Oncol 1991 May;9(5):837-42. doi: 10.1200/JCO.1991.9.5.837. PMID: 2016627

Clinical prediction guides

Endoscopic full-thickness resection: Current status.
Schmidt A, Meier B, Caca K
World J Gastroenterol 2015 Aug 21;21(31):9273-85. doi: 10.3748/wjg.v21.i31.9273. PMID: 26309354Free PMC Article
BRAF V600E mutation-specific antibody: A review.
Ritterhouse LL, Barletta JA
Semin Diagn Pathol 2015 Sep;32(5):400-8. Epub 2015 Feb 7 doi: 10.1053/j.semdp.2015.02.010. PMID: 25744437
Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F
J Pathol 2014 Jan;232(2):199-209. doi: 10.1002/path.4287. PMID: 24122236Free PMC Article
Personalized oncology in interventional radiology.
Abi-Jaoudeh N, Duffy AG, Greten TF, Kohn EC, Clark TW, Wood BJ
J Vasc Interv Radiol 2013 Aug;24(8):1083-92; quiz 1093. doi: 10.1016/j.jvir.2013.04.019. PMID: 23885909Free PMC Article
18F-FDG PET evaluation of the response to therapy for lymphoma and for breast, lung, and colorectal carcinoma.
Kostakoglu L, Goldsmith SJ
J Nucl Med 2003 Feb;44(2):224-39. PMID: 12571214

Recent systematic reviews

Systematic Review and Meta-Analysis: Taurine and Its Association With Colorectal Carcinoma.
Sinha A, Griffith L, Acharjee A
Cancer Med 2024 Dec;13(23):e70424. doi: 10.1002/cam4.70424. PMID: 39632512Free PMC Article
Effects and duration of exercise-based prehabilitation in surgical therapy of colon and rectal cancer: a systematic review and meta-analysis.
Falz R, Bischoff C, Thieme R, Lässing J, Mehdorn M, Stelzner S, Busse M, Gockel I
J Cancer Res Clin Oncol 2022 Sep;148(9):2187-2213. Epub 2022 Jun 13 doi: 10.1007/s00432-022-04088-w. PMID: 35695931Free PMC Article
Electrocoagulation for liver metastases.
Storman D, Swierz MJ, Riemsma RP, Wolff R, Mitus JW, Pedziwiatr M, Kleijnen J, Bala MM
Cochrane Database Syst Rev 2021 Jan 28;1(1):CD009497. doi: 10.1002/14651858.CD009497.pub3. PMID: 33507555Free PMC Article
Helicobacter pylori infection and the risk of colorectal carcinoma: a systematic review and meta-analysis.
Yang F, Xu YL, Zhu RF
Minerva Med 2019 Oct;110(5):464-470. doi: 10.23736/S0026-4806.19.05942-1. PMID: 31368293
Medullary carcinoma in the colorectum: a systematic review and meta-analysis.
Pyo JS, Sohn JH, Kang G
Hum Pathol 2016 Jul;53:91-6. Epub 2016 Mar 19 doi: 10.1016/j.humpath.2016.02.018. PMID: 27001432

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