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Incomplete right bundle branch block

MedGen UID:
82648
Concept ID:
C0262525
Disease or Syndrome
SNOMED CT: Incomplete right bundle branch block (251124007)
 
HPO: HP:6000313

Definition

Right bundle branch block (RBBB) represents an abnormality in the intraventricular electrical conduction system of the human heart, generating enlarged QRS and modified vectors on the electrocardiogram (ECG). Incomplete RBBB (IRBBB) is defined by (i) QRS duration between 110 and 120 ms in adults; (ii) rsr, rsR, or rSR in leads V1 or V2. The R or r deflection is usually wider than the initial R wave. In a minority of patients, a wide and often notched R wave pattern may be seen in leads V1 and/or V2; (iii) S wave of greater duration than R wave or greater than 40 ms in leads I and V6 in adults; and (iv) Normal R peak time in leads V5 and V6 but greater than 50 ms in lead V1. The first 3 criteria should be present to make the diagnosis. When a pure dominant R wave with or without a notch is present in V1, criterion 4 should be satisfied. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncomplete right bundle branch block

Conditions with this feature

Dilated cardiomyopathy 1D
MedGen UID:
316943
Concept ID:
C1832243
Disease or Syndrome
Left ventricular noncompaction is a heart (cardiac) muscle disorder that occurs when the lower left chamber of the heart (left ventricle), which helps the heart pump blood, does not develop correctly. Instead of the muscle being smooth and firm, the cardiac muscle in the left ventricle is thick and appears spongy. The abnormal cardiac muscle is weak and has an impaired ability to pump blood because it either cannot completely contract or it cannot completely relax. For the heart to pump blood normally, cardiac muscle must contract and relax fully.\n\nSome individuals with left ventricular noncompaction experience no symptoms at all; others have heart problems that can include sudden cardiac death. Additional signs and symptoms include abnormal blood clots, irregular heart rhythm (arrhythmia), a sensation of fluttering or pounding in the chest (palpitations), extreme fatigue during exercise (exercise intolerance), shortness of breath (dyspnea), fainting (syncope), swelling of the legs (lymphedema), and trouble laying down flat. Some affected individuals have features of other heart defects. Left ventricular noncompaction can be diagnosed at any age, from birth to late adulthood. Approximately two-thirds of individuals with left ventricular noncompaction develop heart failure.

Professional guidelines

PubMed

Tang J, Yang R, Li H, Wei X, Yang Z, Cai W, Jiang Y, Zhuo G, Meng L, Xu Y
Elife 2024 Nov 11;13 doi: 10.7554/eLife.98169. PMID: 39526735Free PMC Article
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Int Heart J 2011;52(3):159-63. doi: 10.1536/ihj.52.159. PMID: 21646738

Recent clinical studies

Etiology

Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Metsios GS, Wyon M, Patel K, Allen N, Koutedakis Y
Eur J Sport Sci 2020 Aug;20(7):920-925. Epub 2019 Oct 10 doi: 10.1080/17461391.2019.1672793. PMID: 31550203
Alventosa-Zaidin M, Pera G, Roca Saumell C, Mengual Miralles N, Zamora Sanchez MV, Gros Garcia T, Guix Font L, Benitez Camps M, Francisco-Pascual J, Brugada Terradellas J
BMC Fam Pract 2019 May 6;20(1):58. doi: 10.1186/s12875-019-0946-3. PMID: 31060516Free PMC Article
Calcaterra G, Puglisi R
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Rabkin SW, Mathewson FA, Tate RB
J Electrocardiol 1981 Oct;14(4):379-86. doi: 10.1016/s0022-0736(81)81011-4. PMID: 7299308

Diagnosis

Umer M, Sagheer U, Furtado W, Shotwell M, Joshi J, Shetty M, Kalra DK
Radiology 2024 Jul;312(1):e232440. doi: 10.1148/radiol.232440. PMID: 39078295
Floria M, Parteni N, Neagu AI, Sascau RA, Statescu C, Tanase DM
Anatol J Cardiol 2021 Jun;25(6):380-384. doi: 10.5152/AnatolJCardiol.2021.84375. PMID: 34100724Free PMC Article
Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Alventosa-Zaidin M, Pera G, Roca Saumell C, Mengual Miralles N, Zamora Sanchez MV, Gros Garcia T, Guix Font L, Benitez Camps M, Francisco-Pascual J, Brugada Terradellas J
BMC Fam Pract 2019 May 6;20(1):58. doi: 10.1186/s12875-019-0946-3. PMID: 31060516Free PMC Article
Francis J, Antzelevitch C
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Therapy

Minato H, Yoshikawa A, Tsuyama S, Katayanagi K, Hachiya S, Ohta K, Myojo Y
Medicine (Baltimore) 2024 Feb 2;103(5):e37196. doi: 10.1097/MD.0000000000037196. PMID: 38306524Free PMC Article
Mohammadzadeh Shabestari M, Alizadeh L, Moshiri M, Darchini-Maragheh E, Balali-Mood M
Cardiovasc Toxicol 2019 Jun;19(3):220-228. doi: 10.1007/s12012-018-9481-z. PMID: 30242562
Gunes AE, Cimsit M
Diving Hyperb Med 2017 Mar;47(1):55-58. doi: 10.28920/dhm47.1.55-58. PMID: 28357825Free PMC Article
Phillips N, Priestley M, Denniss AR, Uther JB
Anesth Analg 2003 Jul;97(1):264-7, table of contents. doi: 10.1213/01.ane.0000067410.32384.3a. PMID: 12818979
Toubert P, Vorster B
S Afr Med J 1975 Dec 6;49(52):2149. PMID: 1209433

Prognosis

Meziab O, Abrams DJ, Alexander ME, Bevilacqua L, Bezzerides V, Mah DY, Walsh EP, Triedman JK
Congenit Heart Dis 2018 May;13(3):419-427. Epub 2018 Feb 12 doi: 10.1111/chd.12589. PMID: 29431296
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Funct Neurol 2014 Jul-Sep;29(3):159-65. PMID: 25473735Free PMC Article
Calcaterra G, Puglisi R
Int J Cardiol 1989 Aug;24(2):236-8. doi: 10.1016/0167-5273(89)90312-4. PMID: 2767802
Liao YL, Emidy LA, Dyer A, Hewitt JS, Shekelle RB, Paul O, Prineas R, Stamler J
J Am Coll Cardiol 1986 Mar;7(3):492-9. doi: 10.1016/s0735-1097(86)80458-2. PMID: 3950228
Rabkin SW, Mathewson FA, Tate RB
J Electrocardiol 1981 Oct;14(4):379-86. doi: 10.1016/s0022-0736(81)81011-4. PMID: 7299308

Clinical prediction guides

Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Kose S, Vurgun VK, Gokoglan Y, Balli M, Kabul HK
J Cardiovasc Electrophysiol 2020 Dec;31(12):3251-3261. Epub 2020 Oct 11 doi: 10.1111/jce.14765. PMID: 33010075
Diaz-Gonzalez L, Bruña V, Velásquez-Rodriguez J, Valenzuela PL, Valero-Masa MJ, González-Saldívar H, Martinez-Sellés M, Lucia A, Boraita A
Scand J Med Sci Sports 2020 Oct;30(10):1992-1998. Epub 2020 Jul 24 doi: 10.1111/sms.13763. PMID: 32640481
Metsios GS, Wyon M, Patel K, Allen N, Koutedakis Y
Eur J Sport Sci 2020 Aug;20(7):920-925. Epub 2019 Oct 10 doi: 10.1080/17461391.2019.1672793. PMID: 31550203
Alventosa-Zaidin M, Pera G, Roca Saumell C, Mengual Miralles N, Zamora Sanchez MV, Gros Garcia T, Guix Font L, Benitez Camps M, Francisco-Pascual J, Brugada Terradellas J
BMC Fam Pract 2019 May 6;20(1):58. doi: 10.1186/s12875-019-0946-3. PMID: 31060516Free PMC Article

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