U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chylomicronemia syndrome

MedGen UID:
697577
Concept ID:
C1274228
Disease or Syndrome
Synonym: Chylomicronemia
SNOMED CT: Chylomicronemia syndrome (402786009)
 
Related genes: GPIHBP1, LPL, APOC2

Professional guidelines

PubMed

Gouni-Berthold I, Schwarz J, Berthold HK
Curr Atheroscler Rep 2023 Oct;25(10):701-709. Epub 2023 Aug 29 doi: 10.1007/s11883-023-01140-z. PMID: 37642858Free PMC Article
Hernandez P, Passi N, Modarressi T, Kulkarni V, Soni M, Burke F, Bajaj A, Soffer D
Curr Atheroscler Rep 2021 Sep 13;23(11):72. doi: 10.1007/s11883-021-00962-z. PMID: 34515873Free PMC Article
Parhofer KG, Laufs U
Dtsch Arztebl Int 2019 Dec 6;116(49):825-832. doi: 10.3238/arztebl.2019.0825. PMID: 31888796Free PMC Article

Recent clinical studies

Etiology

Stroes ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, Arca M, Ballantyne CM, Soran H, Prohaska TA, Xia S, Ginsberg HN, Witztum JL, Tsimikas S; Balance Investigators
N Engl J Med 2024 May 16;390(19):1781-1792. Epub 2024 Apr 7 doi: 10.1056/NEJMoa2400201. PMID: 38587247
Gouni-Berthold I, Schwarz J, Berthold HK
Curr Atheroscler Rep 2023 Oct;25(10):701-709. Epub 2023 Aug 29 doi: 10.1007/s11883-023-01140-z. PMID: 37642858Free PMC Article
Berberich AJ, Hegele RA
Endocr Rev 2022 Jul 13;43(4):611-653. doi: 10.1210/endrev/bnab037. PMID: 34676866Free PMC Article
Goldberg RB, Chait A
Front Endocrinol (Lausanne) 2020;11:593931. Epub 2020 Oct 23 doi: 10.3389/fendo.2020.593931. PMID: 33193106Free PMC Article
Parhofer KG, Laufs U
Dtsch Arztebl Int 2019 Dec 6;116(49):825-832. doi: 10.3238/arztebl.2019.0825. PMID: 31888796Free PMC Article

Diagnosis

Wilson DP, Williams L, Kavey RW
J Pediatr 2022 Apr;243:200-207. Epub 2021 Dec 17 doi: 10.1016/j.jpeds.2021.12.017. PMID: 34929246
Berberich AJ, Hegele RA
Endocr Rev 2022 Jul 13;43(4):611-653. doi: 10.1210/endrev/bnab037. PMID: 34676866Free PMC Article
Parhofer KG, Laufs U
Dtsch Arztebl Int 2019 Dec 6;116(49):825-832. doi: 10.3238/arztebl.2019.0825. PMID: 31888796Free PMC Article
Falko JM
Endocr Pract 2018 Aug;24(8):756-763. doi: 10.4158/EP-2018-0157. PMID: 30183397
Chait A, Brunzell JD
Adv Intern Med 1992;37:249-73. PMID: 1557997

Therapy

Stroes ESG, Alexander VJ, Karwatowska-Prokopczuk E, Hegele RA, Arca M, Ballantyne CM, Soran H, Prohaska TA, Xia S, Ginsberg HN, Witztum JL, Tsimikas S; Balance Investigators
N Engl J Med 2024 May 16;390(19):1781-1792. Epub 2024 Apr 7 doi: 10.1056/NEJMoa2400201. PMID: 38587247
Gouni-Berthold I, Schwarz J, Berthold HK
Curr Atheroscler Rep 2023 Oct;25(10):701-709. Epub 2023 Aug 29 doi: 10.1007/s11883-023-01140-z. PMID: 37642858Free PMC Article
Egli M, Manoharan M
Nucleic Acids Res 2023 Apr 11;51(6):2529-2573. doi: 10.1093/nar/gkad067. PMID: 36881759Free PMC Article
Hernandez P, Passi N, Modarressi T, Kulkarni V, Soni M, Burke F, Bajaj A, Soffer D
Curr Atheroscler Rep 2021 Sep 13;23(11):72. doi: 10.1007/s11883-021-00962-z. PMID: 34515873Free PMC Article
Parhofer KG, Laufs U
Dtsch Arztebl Int 2019 Dec 6;116(49):825-832. doi: 10.3238/arztebl.2019.0825. PMID: 31888796Free PMC Article

Prognosis

Watts GF, Rosenson RS, Hegele RA, Goldberg IJ, Gallo A, Mertens A, Baass A, Zhou R, Muhsin M, Hellawell J, Leeper NJ, Gaudet D; PALISADE Study Group
N Engl J Med 2025 Jan 9;392(2):127-137. Epub 2024 Sep 2 doi: 10.1056/NEJMoa2409368. PMID: 39225259
Blanco Echevarría A, Ariza Corbo MJ, Muñiz-Grijalvo O, Díaz-Díaz JL
Clin Investig Arterioscler 2024 Dec;36 Suppl 2:S18-S24. doi: 10.1016/j.arteri.2024.10.006. PMID: 39672668
Vigna GB, Citroni N, Tarugi P, Fellin R
J Clin Lipidol 2022 Sep-Oct;16(5):591-595. Epub 2022 Jul 31 doi: 10.1016/j.jacl.2022.07.013. PMID: 35945124
Calandra S, Priore Oliva C, Tarugi P, Bertolini S
Curr Opin Lipidol 2006 Apr;17(2):122-7. doi: 10.1097/01.mol.0000217892.00618.54. PMID: 16531747
Chait A, Brunzell JD
Adv Intern Med 1992;37:249-73. PMID: 1557997

Clinical prediction guides

Rosenson RS, Gaudet D, Ballantyne CM, Baum SJ, Bergeron J, Kershaw EE, Moriarty PM, Rubba P, Whitcomb DC, Banerjee P, Gewitz A, Gonzaga-Jauregui C, McGinniss J, Ponda MP, Pordy R, Zhao J, Rader DJ
Nat Med 2023 Mar;29(3):729-737. Epub 2023 Mar 6 doi: 10.1038/s41591-023-02222-w. PMID: 36879129Free PMC Article
Fantino M, Paquette M, Blais C, Saint-Pierre N, Bourque L, Baass A, Bernard S
Nutr Res 2022 May;101:43-52. Epub 2022 Feb 18 doi: 10.1016/j.nutres.2022.02.001. PMID: 35367870
Dron JS, Hegele RA
Front Endocrinol (Lausanne) 2020;11:455. Epub 2020 Jul 24 doi: 10.3389/fendo.2020.00455. PMID: 32793115Free PMC Article
Baass A, Paquette M, Bernard S, Hegele RA
J Intern Med 2020 Apr;287(4):340-348. Epub 2020 Jan 8 doi: 10.1111/joim.13016. PMID: 31840878
Paquette M, Bernard S, Hegele RA, Baass A
Atherosclerosis 2019 Apr;283:137-142. Epub 2018 Dec 28 doi: 10.1016/j.atherosclerosis.2018.12.019. PMID: 30655019

Recent systematic reviews

Tripathi M, Wong A, Solomon V, Yassine HN
Endocr Pract 2021 Jan;27(1):71-76. Epub 2020 Nov 18 doi: 10.4158/EP-2020-0135. PMID: 33475504
Green ML
J Gen Intern Med 2002 Oct;17(10):797-810. doi: 10.1046/j.1525-1497.2002.20201.x. PMID: 12390557Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...