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Metastatic Breast Lobular Carcinoma

MedGen UID:
437465
•Concept ID:
C2698204
•
Neoplastic Process
Synonym: Metastatic Lobular Breast Carcinoma

Definition

A lobular breast carcinoma that has spread from the original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Breast Lobular Carcinoma

Professional guidelines

PubMed

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Efficacy and toxicity of eribulin treatment in metastatic breast cancer patients.
Brems-Eskildsen AS, Kristoffersen KB, Linnet S, Lörincz T, Langkjer ST
Acta Oncol 2019 Jan;58(1):119-121. Epub 2018 Aug 11 doi: 10.1080/0284186X.2018.1497301. PMID: 30101626
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754

Recent clinical studies

Etiology

Predictors and outcomes of cutaneous metastatic breast carcinoma: a retrospective, single-institution review.
Choo ZY, Xu AZ
Arch Dermatol Res 2023 Nov;315(9):2725-2728. Epub 2023 Jul 25 doi: 10.1007/s00403-023-02676-5. PMID: 37490055
Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
De novo metastatic lobular breast carcinoma: A population-based study from SEER database.
Sun MS, Yan HC, Gao M, Liu HJ, Xu L
Asian J Surg 2022 Dec;45(12):2608-2617. Epub 2022 Jan 7 doi: 10.1016/j.asjsur.2021.12.036. PMID: 35012851
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
Lobular carcinoma of the breast: presentation, histopathological features and management of rectal metastasis.
Elsaify W, Kanwar A, Nagarajan S
Breast J 2012 Nov-Dec;18(6):597-9. doi: 10.1111/tbj.12037. PMID: 23127118

Diagnosis

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Synchronous endometrial and gastric metastases of invasive lobular breast carcinomas.
Lai MJ, Lai CL, Huang IH, Yu JC, Lee HS, Dai MS
Taiwan J Obstet Gynecol 2016 Feb;55(1):131-4. doi: 10.1016/j.tjog.2014.10.012. PMID: 26927266
Relapse of invasive lobular carcinoma.
Mallon E, Varga Z
Breast Dis 2008-2009;30:53-6. doi: 10.3233/BD-2009-0284. PMID: 19850996
Cytomorphological features of metastatic mammary lobular carcinoma in cervicovaginal smears: report of a case and review of literature.
Haji BE, Kapila K, Francis IM, Temmim L, Ahmed MS
Cytopathology 2005 Feb;16(1):42-8. doi: 10.1111/j.1365-2303.2004.00211.x. PMID: 15859315

Therapy

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.
Van Baelen K, Geukens T, Maetens M, Tjan-Heijnen V, Lord CJ, Linn S, Bidard FC, Richard F, Yang WW, Steele RE, Pettitt SJ, Van Ongeval C, De Schepper M, Isnaldi E, Nevelsteen I, Smeets A, Punie K, Voorwerk L, Wildiers H, Floris G, Vincent-Salomon A, Derksen PWB, Neven P, Senkus E, Sawyer E, Kok M, Desmedt C
Ann Oncol 2022 Aug;33(8):769-785. Epub 2022 May 21 doi: 10.1016/j.annonc.2022.05.006. PMID: 35605746
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study.
Kuehn T, Bauerfeind I, Fehm T, Fleige B, Hausschild M, Helms G, Lebeau A, Liedtke C, von Minckwitz G, Nekljudova V, Schmatloch S, Schrenk P, Staebler A, Untch M
Lancet Oncol 2013 Jun;14(7):609-18. Epub 2013 May 15 doi: 10.1016/S1470-2045(13)70166-9. PMID: 23683750
Treatment of breast cancer.
Maughan KL, Lutterbie MA, Ham PS
Am Fam Physician 2010 Jun 1;81(11):1339-46. PMID: 20521754
Breast cancer during pregnancy: cases and review of treatment and prognosis.
Schotte K, Cocquyt V, Van den Broecke R, Dhondt M, Van Belle S
Acta Clin Belg 2000 Mar-Apr;55(2):102-9. doi: 10.1080/17843286.2000.11754279. PMID: 10881376

Prognosis

Predictors and outcomes of cutaneous metastatic breast carcinoma: a retrospective, single-institution review.
Choo ZY, Xu AZ
Arch Dermatol Res 2023 Nov;315(9):2725-2728. Epub 2023 Jul 25 doi: 10.1007/s00403-023-02676-5. PMID: 37490055
Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Metastatic lobular carcinoma of the breast: an unusual case.
Carroll J, Vujcich E, Lambrianides AL
ANZ J Surg 2018 Apr;88(4):378-379. Epub 2015 Nov 17 doi: 10.1111/ans.13370. PMID: 26573996
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.
Sávolt Á, Péley G, Polgár C, Udvarhelyi N, Rubovszky G, Kovács E, Győrffy B, Kásler M, Mátrai Z
Eur J Surg Oncol 2017 Apr;43(4):672-679. Epub 2017 Jan 16 doi: 10.1016/j.ejso.2016.12.011. PMID: 28139362
Metastatic manifestations of invasive lobular breast carcinoma.
Doyle DJ, Relihan N, Redmond HP, Barry JE
Clin Radiol 2005 Feb;60(2):271-4. doi: 10.1016/j.crad.2004.09.005. PMID: 15664584

Clinical prediction guides

Predictors and outcomes of cutaneous metastatic breast carcinoma: a retrospective, single-institution review.
Choo ZY, Xu AZ
Arch Dermatol Res 2023 Nov;315(9):2725-2728. Epub 2023 Jul 25 doi: 10.1007/s00403-023-02676-5. PMID: 37490055
Unexpected finding.
Vallianou NG, Stavrinou N, Panagopoulos F, Geladari E, Sykaras AG, Vourlakou C
J Clin Pathol 2021 Apr;74(4):e6. Epub 2020 Oct 13 doi: 10.1136/jclinpath-2020-206770. PMID: 33051289
Randomized Trial Comparing Resection of Primary Tumor with No Surgery in Stage IV Breast Cancer at Presentation: Protocol MF07-01.
Soran A, Ozmen V, Ozbas S, Karanlik H, Muslumanoglu M, Igci A, Canturk Z, Utkan Z, Ozaslan C, Evrensel T, Uras C, Aksaz E, Soyder A, Ugurlu U, Col C, Cabioglu N, Bozkurt B, Uzunkoy A, Koksal N, Gulluoglu BM, Unal B, Atalay C, Yıldırım E, Erdem E, Salimoglu S, Sezer A, Koyuncu A, Gurleyik G, Alagol H, Ulufi N, Berberoglu U, Dulger M, Cengiz O, Sezgin E, Johnson R
Ann Surg Oncol 2018 Oct;25(11):3141-3149. Epub 2018 May 17 doi: 10.1245/s10434-018-6494-6. PMID: 29777404
Lobular breast cancer: Clinical, molecular and morphological characteristics.
Christgen M, Steinemann D, Kühnle E, Länger F, Gluz O, Harbeck N, Kreipe H
Pathol Res Pract 2016 Jul;212(7):583-97. Epub 2016 May 5 doi: 10.1016/j.prp.2016.05.002. PMID: 27233940
Invasive Pleomorphic Lobular Carcinoma of the Breast: Pathologic, Clinical, and Therapeutic Considerations.
Al-Baimani K, Bazzarelli A, Clemons M, Robertson SJ, Addison C, Arnaout A
Clin Breast Cancer 2015 Dec;15(6):421-5. Epub 2015 Jun 22 doi: 10.1016/j.clbc.2015.06.010. PMID: 26209026

Recent systematic reviews

The Assisi think tank focus review on postoperative radiation for lobular breast cancer.
Kaidar-Person O, Ratosa I, Franco P, Masiello V, Marazzi F, Pedretti S, Ciabattoni A, Leonardi MC, Tramm T, Coles CE, Meattini I, Arenas M, Offersen BV, Boersma LJ, Valentini V, Dodwell D, Poortmans P, Aristei C; Assisi Think Tank Meeting ATTM investigators
Radiother Oncol 2024 Dec;201:110573. Epub 2024 Oct 11 doi: 10.1016/j.radonc.2024.110573. PMID: 39395669
Impact of Preoperative Magnetic Resonance Imaging on Surgical Outcomes in Women with Invasive Breast Cancer: A Systematic Review and Meta-Analysis.
Li L, Zhang Q, Qian C, Lin H
Int J Clin Pract 2022;2022:6440952. Epub 2022 Aug 25 doi: 10.1155/2022/6440952. PMID: 36081810Free PMC Article
Carcinomatous cirrhosis as radiographically occult liver metastases of breast cancer: A systematic literature review.
Hoshina H, Takei H, Nakamura M, Nishimoto F, Hanamura S
Cancer Treat Res Commun 2021;28:100388. Epub 2021 May 13 doi: 10.1016/j.ctarc.2021.100388. PMID: 34022480
Bladder Metastases from Breast Cancer: Managing the Unexpected. A Systematic Review.
Sanguedolce F, Landriscina M, Ambrosi A, Tartaglia N, Cianci P, Di Millo M, Carrieri G, Bufo P, Cormio L
Urol Int 2018;101(2):125-131. Epub 2017 Oct 20 doi: 10.1159/000481576. PMID: 29055945
High frequency of lobular breast cancer in distant metastases to the orbit.
Raap M, Antonopoulos W, Dämmrich M, Christgen H, Steinmann D, Länger F, Lehmann U, Kreipe H, Christgen M
Cancer Med 2015 Jan;4(1):104-11. Epub 2014 Oct 30 doi: 10.1002/cam4.331. PMID: 25355547Free PMC Article

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