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Benign neoplasm

MedGen UID:
39483
Concept ID:
C0086692
Neoplastic Process
Synonyms: Benign Neoplasm; Benign Neoplasms; Neoplasm, Benign; Neoplasms, Benign
SNOMED CT: Benign tumor morphology (3898006); Benign neoplasm (3898006); Benign neoplastic disease (20376005); Neoplasm, benign (3898006); Tumor, benign (3898006); Unclassified tumor, benign (3898006)
 
Monarch Initiative: MONDO:0005165

Definition

A neoplasm characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm

Professional guidelines

PubMed

Ali M, Ciebiera M, Wlodarczyk M, Alkhrait S, Maajid E, Yang Q, Hsia SM, Al-Hendy A
Drugs 2023 Dec;83(18):1649-1675. Epub 2023 Nov 3 doi: 10.1007/s40265-023-01958-6. PMID: 37922098
Sugai S, Nishijima K, Enomoto T
Sex Transm Dis 2021 Jun 1;48(6):403-409. doi: 10.1097/OLQ.0000000000001322. PMID: 33093288Free PMC Article
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096

Recent clinical studies

Etiology

Chehad AS, Hamza O, Mansoul T
Pediatr Dermatol 2023 Jul-Aug;40(4):647-650. Epub 2023 Jun 14 doi: 10.1111/pde.15363. PMID: 37314056
Sugai S, Nishijima K, Enomoto T
Sex Transm Dis 2021 Jun 1;48(6):403-409. doi: 10.1097/OLQ.0000000000001322. PMID: 33093288Free PMC Article
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Lemaitre L, Claudon M, Dubrulle F, Mazeman E
Semin Ultrasound CT MR 1997 Apr;18(2):100-14. doi: 10.1016/s0887-2171(97)90054-8. PMID: 9163829
Nuzzo G, Lemmo G, Marrocco-Trischitta MM, Boldrini G, Giovannini I
J Surg Oncol 1996 Mar;61(3):234-7. doi: 10.1002/(SICI)1096-9098(199603)61:3<234::AID-JSO14>3.0.CO;2-7. PMID: 8637214

Diagnosis

Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895
Mendenhall WM, Mendenhall CM, Reith JD, Scarborough MT, Gibbs CP, Mendenhall NP
Am J Clin Oncol 2006 Dec;29(6):548-50. doi: 10.1097/01.coc.0000239142.48188.f6. PMID: 17148989
Craver RD, Correa-Gracian H, Heinrich S
Hum Pathol 1997 Jun;28(6):745-7. doi: 10.1016/s0046-8177(97)90186-6. PMID: 9191011
Tomasini C, Aloi F, Pippione M
Dermatology 1996;192(2):160-3. doi: 10.1159/000246348. PMID: 8829503
Beebe MM, Smith MD
J Pediatr Surg 1993 Dec;28(12):1626-7. doi: 10.1016/0022-3468(93)90122-2. PMID: 8301515

Therapy

Lu Y, Yao Y, Zhai S, Ni F, Wang J, Chen F, Zhang Y, Li H, Hu H, Zhang H, Yu B, Chen H, Huang X, Ding W, Lu D
Int J Surg 2024 Oct 1;110(10):6541-6550. doi: 10.1097/JS9.0000000000001814. PMID: 38884272Free PMC Article
Sugai S, Nishijima K, Enomoto T
Sex Transm Dis 2021 Jun 1;48(6):403-409. doi: 10.1097/OLQ.0000000000001322. PMID: 33093288Free PMC Article
D'Angelo SP, Mahoney MR, Van Tine BA, Atkins J, Milhem MM, Jahagirdar BN, Antonescu CR, Horvath E, Tap WD, Schwartz GK, Streicher H
Lancet Oncol 2018 Mar;19(3):416-426. Epub 2018 Jan 19 doi: 10.1016/S1470-2045(18)30006-8. PMID: 29370992Free PMC Article
Schlosser KA
JAAPA 2009 May;22(5):46-9. doi: 10.1097/01720610-200905000-00010. PMID: 19469391
Craver RD, Correa-Gracian H, Heinrich S
Hum Pathol 1997 Jun;28(6):745-7. doi: 10.1016/s0046-8177(97)90186-6. PMID: 9191011

Prognosis

Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895
Mendenhall WM, Mendenhall CM, Reith JD, Scarborough MT, Gibbs CP, Mendenhall NP
Am J Clin Oncol 2006 Dec;29(6):548-50. doi: 10.1097/01.coc.0000239142.48188.f6. PMID: 17148989
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Nuzzo G, Lemmo G, Marrocco-Trischitta MM, Boldrini G, Giovannini I
J Surg Oncol 1996 Mar;61(3):234-7. doi: 10.1002/(SICI)1096-9098(199603)61:3<234::AID-JSO14>3.0.CO;2-7. PMID: 8637214
Pasic TR, Makielski K
Otolaryngol Head Neck Surg 1990 Dec;103(6):943-6. doi: 10.1177/019459989010300610. PMID: 2126128

Clinical prediction guides

Schick B, Pillong L, Wenzel G, Wemmert S
Int J Mol Sci 2022 Feb 9;23(4) doi: 10.3390/ijms23041932. PMID: 35216046Free PMC Article
Ostrofsky M, Morkel JA, Titinchi F
J Stomatol Oral Maxillofac Surg 2019 Dec;120(6):584-587. Epub 2019 Jan 25 doi: 10.1016/j.jormas.2019.01.013. PMID: 30685345
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848
Willcox TM, Speer RW, Schlinkert RT, Sarr MG
J Gastrointest Surg 2000 Nov-Dec;4(6):611-3. doi: 10.1016/s1091-255x(00)80110-9. PMID: 11307096
Gaspar L, Mascarenhas F, da Costa MS, Dias JS, Afonso JG, Silvestre ME
Radiother Oncol 1993 Oct;29(1):45-50. doi: 10.1016/0167-8140(93)90172-5. PMID: 8295987

Recent systematic reviews

Alberto PL, Ashim S, Megan K, Wei Z, Nestor G, Matthew Z, Dayana M, Marcelo V, John W
Head Neck Pathol 2024 Nov 30;18(1):126. doi: 10.1007/s12105-024-01730-6. PMID: 39614964Free PMC Article
Trent MS, Goshtasbi K, Hui L, Stuyt JAG, Adappa ND, Palmer JN, Kuan EC
Otolaryngol Head Neck Surg 2022 Sep;167(3):425-433. Epub 2021 Oct 12 doi: 10.1177/01945998211051975. PMID: 34637363
Le Donne M, Jouan R, Bourlet J, Louvrier A, Ducret M, Sigaux N
J Stomatol Oral Maxillofac Surg 2022 Apr;123(2):233-238. Epub 2021 Apr 30 doi: 10.1016/j.jormas.2021.04.007. PMID: 33933668
Sugai S, Nishijima K, Enomoto T
Sex Transm Dis 2021 Jun 1;48(6):403-409. doi: 10.1097/OLQ.0000000000001322. PMID: 33093288Free PMC Article
Knight J, Ratnasingham K
Int J Surg 2015 Jul;19:137-45. Epub 2015 May 6 doi: 10.1016/j.ijsu.2015.04.084. PMID: 25958295

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