Benign eccrine breast spiradenoma

MedGen UID:: 231933
•Concept ID:: C1332492
•: Neoplastic Process

Synonyms:	Benign Breast Eccrine Spiradenoma; benign breast eccrine spiradenoma; Benign Eccrine Breast Spiradenoma; benign eccrine breast spiradenoma; Benign Eccrine Spiradenoma of Breast; benign eccrine spiradenoma of breast; Benign Eccrine Spiradenoma of the Breast; benign eccrine spiradenoma of the breast; Breast Spiradenoma

Monarch Initiative:	MONDO:0002055

Definition

A very rare, benign sweat gland neoplasm that affects the breast. It is characterized by the proliferation of basaloid epithelial cells. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBenign eccrine breast spiradenoma

Pathological process
- Disease
  - Neoplasm
    - Neoplasm by Special Category
      - Benign neoplasm
        Breast benign neoplasm
        Benign eccrine breast spiradenoma

Recent clinical studies

Etiology

GATA3 Expression in Normal Skin and in Benign and Malignant Epidermal and Cutaneous Adnexal Neoplasms.

Mertens RB, de Peralta-Venturina MN, Balzer BL, Frishberg DP
Am J Dermatopathol 2015 Dec;37(12):885-91. doi: 10.1097/DAD.0000000000000306. PMID: 26595821 Free PMC Article

Papillary transitional cell carcinoma of the breast: a report of five cases with distinction from eccrine acrospiroma.

Mooney EE, Tavassoli FA
Mod Pathol 1999 Mar;12(3):287-94. PMID: 10102614

See all (2)

Diagnosis

GATA3 Expression in Normal Skin and in Benign and Malignant Epidermal and Cutaneous Adnexal Neoplasms.

Mertens RB, de Peralta-Venturina MN, Balzer BL, Frishberg DP
Am J Dermatopathol 2015 Dec;37(12):885-91. doi: 10.1097/DAD.0000000000000306. PMID: 26595821 Free PMC Article

Eccrine spiradenoma arising in the breast misdiagnosed as an epidermal inclusion cyst.

Lee HH, Park SH, Choi HY, Park HK
Korean J Radiol 2011 Mar-Apr;12(2):256-60. Epub 2011 Mar 3 doi: 10.3348/kjr.2011.12.2.256. PMID: 21430945 Free PMC Article

Carcinoma ex spiradenoma/cylindroma confirmed by immunohistochemical and molecular loss-of-heterozygosity profiling.

Jukic DM, Drogowski LM, Davie JR
Am J Dermatopathol 2009 Oct;31(7):702-8. doi: 10.1097/DAD.0b013e3181a6b6f4. PMID: 19684510

Apocrine poroma of the breast.

Azma A, Tawfik O, Casparian JM
Breast J 2001 May-Jun;7(3):195-8. doi: 10.1046/j.1524-4741.2001.007003195.x. PMID: 11469936

An uncommon breast tumour: the malignant eccrine spiradenoma. A case report.

Thomas B, Duwel V, Proot L, Vanvuchelen J
Acta Chir Belg 1993 Nov-Dec;93(6):295-8. PMID: 8140844

See all (8)